LOCUS       NM_001136073            6845 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus nuclear factor of activated T cells, cytoplasmic,
            calcineurin dependent 2 (Nfatc2), transcript variant 4, mRNA.
ACCESSION   NM_001136073
VERSION     NM_001136073.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6845)
  AUTHORS   Bulow,S., Ederer,K.U., Holzinger,J.M., Zeller,L., Werner,M.,
            Toelge,M., Pfab,C., Hirsch,S., Gopferich,F., Hiergeist,A.,
            Berberich-Siebelt,F. and Gessner,A.
  TITLE     Bactericidal/permeability-increasing protein instructs dendritic
            cells to elicit Th22 cell response
  JOURNAL   Cell Rep 43 (3), 113929 (2024)
   PUBMED   38457343
REFERENCE   2  (bases 1 to 6845)
  AUTHORS   Vittal,R., Walker,N.M., McLinden,A.P., Braeuer,R.R., Ke,F.,
            Fattahi,F., Combs,M.P., Misumi,K., Aoki,Y., Wheeler,D.S.,
            Wilke,C.A., Huang,S.K., Moore,B.B., Cao,P. and Lama,V.N.
  TITLE     Genetic deficiency of the transcription factor NFAT1 confers
            protection against fibrogenic responses independent of immune
            influx
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 326 (1), L39-L51 (2024)
   PUBMED   37933452
  REMARK    GeneRIF: Genetic deficiency of the transcription factor NFAT1
            confers protection against fibrogenic responses independent of
            immune influx.
REFERENCE   3  (bases 1 to 6845)
  AUTHORS   Shim,J.A., Lee,S.M., Jeong,J.W., Kim,H., Son,W.J., Park,J.H.,
            Song,P., Im,S.H., Bae,S., Park,J.H., Jo,Y. and Hong,C.
  TITLE     NFAT1 and NFkappaB regulates expression of the common gamma-chain
            cytokine receptor in activated T cells
  JOURNAL   Cell Commun Signal 21 (1), 309 (2023)
   PUBMED   37904191
  REMARK    GeneRIF: NFAT1 and NFkappaB regulates expression of the common
            gamma-chain cytokine receptor in activated T cells.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6845)
  AUTHORS   Fu,Y., Wang,J., Liu,C., Liao,K., Gao,X., Tang,R., Fan,B., Hong,Y.,
            Xiao,N., Xiao,C. and Liu,W.H.
  TITLE     Glycogen synthase kinase 3 controls T-cell exhaustion by regulating
            NFAT activation
  JOURNAL   Cell Mol Immunol 20 (10), 1127-1139 (2023)
   PUBMED   37553428
  REMARK    GeneRIF: Glycogen synthase kinase 3 controls T-cell exhaustion by
            regulating NFAT activation.
REFERENCE   5  (bases 1 to 6845)
  AUTHORS   Wan,X., Zhao,S., Dai,Y., Zhang,J., Shen,Y., Gong,L. and Le,Q.
  TITLE     WNT16b promotes the proliferation and self-renewal of human limbal
            epithelial stem/progenitor cells via activating the
            calcium/calcineurin A/NFATC2 pathway
  JOURNAL   Cell Prolif 56 (10), e13460 (2023)
   PUBMED   36974338
  REMARK    GeneRIF: WNT16b promotes the proliferation and self-renewal of
            human limbal epithelial stem/progenitor cells via activating the
            calcium/calcineurin A/NFATC2 pathway.
REFERENCE   6  (bases 1 to 6845)
  AUTHORS   Vihma,H., Pruunsild,P. and Timmusk,T.
  TITLE     Alternative splicing and expression of human and mouse NFAT genes
  JOURNAL   Genomics 92 (5), 279-291 (2008)
   PUBMED   18675896
REFERENCE   7  (bases 1 to 6845)
  AUTHORS   Ho,S.N., Thomas,D.J., Timmerman,L.A., Li,X., Francke,U. and
            Crabtree,G.R.
  TITLE     NFATc3, a lymphoid-specific NFATc family member that is
            calcium-regulated and exhibits distinct DNA binding specificity
  JOURNAL   J Biol Chem 270 (34), 19898-19907 (1995)
   PUBMED   7650004
REFERENCE   8  (bases 1 to 6845)
  AUTHORS   Jain,J., Burgeon,E., Badalian,T.M., Hogan,P.G. and Rao,A.
  TITLE     A similar DNA-binding motif in NFAT family proteins and the Rel
            homology region
  JOURNAL   J Biol Chem 270 (8), 4138-4145 (1995)
   PUBMED   7876165
REFERENCE   9  (bases 1 to 6845)
  AUTHORS   Li,X., Ho,S.N., Luna,J., Giacalone,J., Thomas,D.J., Timmerman,L.A.,
            Crabtree,G.R. and Francke,U.
  TITLE     Cloning and chromosomal localization of the human and murine genes
            for the T-cell transcription factors NFATc and NFATp
  JOURNAL   Cytogenet Cell Genet 68 (3-4), 185-191 (1995)
   PUBMED   7842733
REFERENCE   10 (bases 1 to 6845)
  AUTHORS   Ho,A.M., Jain,J., Rao,A. and Hogan,P.G.
  TITLE     Expression of the transcription factor NFATp in a neuronal cell
            line and in the murine nervous system
  JOURNAL   J Biol Chem 269 (45), 28181-28186 (1994)
   PUBMED   7961754
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK135414.1, EU887582.1 and BP757417.1.
            
            On Mar 27, 2014 this sequence version replaced NM_001136073.1.
            
            Transcript Variant: This variant (4, also known as IB-IIL-Xa)
            contains an additional exon that results in an alternate 3' coding
            region and 3' UTR, compared to variant 1. The encoded isoform (d)
            has a distinct C-terminus and is shorter than isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU887582.1, SRR10223971.3526.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AK135414.1         2-175
            175-6825            EU887582.1         1-6651
            6826-6845           BP757417.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..6845
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 88.91 cM"
     gene            1..6845
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /note="nuclear factor of activated T cells, cytoplasmic,
                     calcineurin dependent 2"
                     /db_xref="GeneID:18019"
                     /db_xref="MGI:MGI:102463"
     exon            1..304
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..2946
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /note="isoform d is encoded by transcript variant 4;
                     nuclear factor of activated T-cells, cytoplasmic 2; NFAT
                     pre-existing subunit; T-cell transcription factor NFAT1"
                     /codon_start=1
                     /product="nuclear factor of activated T-cells, cytoplasmic
                     2 isoform d"
                     /protein_id="NP_001129545.1"
                     /db_xref="CCDS:CCDS50803.1"
                     /db_xref="GeneID:18019"
                     /db_xref="MGI:MGI:102463"
                     /translation="MDVPEPQPDPDGGDGPGHEPGGSPQDELDFSILFDYDYLNPIEE
                     EPIAHKAISSPSGLAYPDDVLDYGLKPCNPLASLSGEPPGRFGEPDSIGFQNFLSPVK
                     PAGASGPSPRIEITPSHELMQAGGALRGRDAGLSPEQPALALAGVAASPRFTLPVPGY
                     EGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNAGPDDLCPQFQNIPAHYSPRT
                     SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRS
                     PSPQPSPHVALQDDSIPAGYPPTAGSAVLMDALNTLATDSPCGIPSKIWKTSPDPTPV
                     STAPSKAGLARHIYPTVEFLGPCEQEERRNSAPESILLVPPTWPKQLVPAIPICSIPV
                     TASLPPLEWPLSNQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGY
                     MENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPK
                     NNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHVPEPSGRIVSLQAAS
                     NPIECSQRSAHELPMVERQDMDSCLVYGGQQMILTGQNFTAESKVVFMEKTTDGQQIW
                     EMEATVDKDKSQPNMLFVEIPEYRNKHIRVPVKVNFYVINGKRKRSQPQHFTYHPVPA
                     IKTEPSDEYEPSLICSPAHGGLGSQPYYPQHPMLAESPSCLVATMAPCQQFRSGLSSP
                     DARYQQQSPAAALYQRSKSLSPGLLGYQQPSLLAAPLGLADAHRSVLVHAGSQGQGQG
                     STLPHTSSASQQASPVIHYSPTNQQLRGGGHQEFQHIMYCENFGPSSARPGPPPINQG
                     QRLSPGAYPTVIQQQTAPSQRAAKNGPSDQKEALPTGVTVKQEQNLDQTYLDDELIDT
                     HLSWIQNIL"
     exon            305..1340
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1512
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1715
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1888
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..2029
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2085
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2212
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2902
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..2988
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     exon            2989..6828
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6804..6809
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /note="hexamer: AATAAA"
     polyA_site      6828
                     /gene="Nfatc2"
                     /gene_synonym="NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp"
                     /note="major polyA site"
ORIGIN      
        1 aggctgcaac aggtgccttg agcaggaagc tcgcgccgcc acccgctccc cggacgcgtc
       61 caggacccac tgcgccgtga gccatcctcg gcctcaccgt gcgccacaga tacggtgacc
      121 cctgctctgc gccccgcgac tctatacgaa cccgcatccc gaacgccccg agccatggac
      181 gtcccggagc cgcagcccga ccccgatggc ggggacggcc ccggccacga gcccgggggc
      241 agtccccaag acgagctgga cttttccatc ctcttcgatt atgactatct gaaccctatc
      301 gaagaagaac cgatcgcaca taaggccatc agctcaccct ccggactcgc atacccggat
      361 gatgtcctgg actatggcct caagccatgc aacccccttg ccagtctctc tggcgagccc
      421 cctggccggt tcggagagcc ggatagtata gggttccaga actttctgag cccggtcaag
      481 ccagcagggg cttcgggccc gagccctcgg atcgagatca ctccatccca cgaactgatg
      541 caggcagggg gggccctccg tgggagagac gccggcctgt cccccgagca gccggccctg
      601 gccctggccg gcgtggccgc cagcccgagg ttcacactgc ccgtgcccgg ctacgagggc
      661 taccgcgagc cgctttgctt gagccccgct agcagcggct cctctgccag cttcatttct
      721 gacaccttct ccccctacac ctcgccctgc gtctcaccca ataacgccgg gcccgacgac
      781 ctgtgtcccc agtttcaaaa catccctgct cattattccc ccagaacctc tccaataatg
      841 tcacctcgaa ccagcctcgc cgaggacagc tgcctgggcc gacactcgcc cgtgccccgt
      901 ccggcatccc gctcctcctc acccggtgcc aagcggaggc attcgtgcgc agaggctttg
      961 gttgctcctc tgcccgcagc ctcaccccag cgctcccgga gcccctcgcc acagccctcg
     1021 cctcacgtgg cactgcagga cgacagcatc cccgctgggt acccccccac ggccggctct
     1081 gctgttctca tggatgccct caacaccctg gccaccgact cgccctgcgg gatcccctcc
     1141 aagatatgga agaccagtcc tgacccgacg cctgtgtcca ccgctccgtc caaggctggc
     1201 ctggcccgcc acatctaccc tactgtggag ttcctggggc catgtgagca ggaggagagg
     1261 aggaattccg ctccagagtc catcctgctg gtaccaccta cttggcccaa gcagttggtg
     1321 ccggccattc ccatctgcag catccctgtg actgcatccc tcccaccact cgagtggcca
     1381 ctctccaatc agtcgggctc ctatgagcta cggattgagg tccaacccaa gccccatcac
     1441 cgggcccact atgagacgga gggcagccgt ggcgctgtca aagccccaac aggaggacac
     1501 cctgtggtgc agctccacgg ctacatggag aacaagcctc tggggcttca gatcttcatt
     1561 gggacagcag atgagaggat ccttaagccg cacgccttct accaagtaca caggatcact
     1621 gggaaaacgg tcaccaccac gagctatgag aagatcgtag gcaacaccaa ggtcctggag
     1681 atccccctgg agccaaagaa caacatgaga gccaccatcg actgtgcagg catcctgaag
     1741 ctccgaaacg ctgacatcga gctgcggaag ggcgagacgg acatcggcag gaagaacacg
     1801 cgtgtgcgcc tggtgttccg cgtgcacgtc ccagagccca gtgggcgcat cgtctccctg
     1861 caggctgcgt ccaaccccat cgagtgctct cagcgctctg cccacgagct gcccatggtg
     1921 gagagacaag acatggacag ctgcctggtc tacgggggcc agcagatgat cctcacgggc
     1981 cagaacttca cagcggagtc caaggttgtg ttcatggaga agactacaga tgggcagcag
     2041 atttgggaga tggaagctac ggtggataaa gacaagagcc agcctaacat gctttttgtt
     2101 gagatccccg agtatcggaa caagcacatc cgcgtgcccg tgaaagtcaa cttctacgtc
     2161 atcaacggaa agaggaaacg aagtcagcca cagcacttta cctaccaccc agtccctgcc
     2221 atcaagacag agcccagcga tgagtatgaa ccatctttga tctgcagccc cgcccatgga
     2281 ggcctgggga gccagccata ttacccacag cacccaatgc tggccgagtc cccctcctgc
     2341 cttgtggcta ccatggcccc ctgccaacag ttccgctcgg ggctctcatc ccccgatgct
     2401 cgctaccaac agcagagccc cgcagctgcc ctctaccaga gaagcaagag cctgagtccc
     2461 ggcctgctgg gctaccagca gccgtccctc ctggcagcac ccttgggtct ggctgatgcc
     2521 caccgctctg tgctggtgca tgctggttct caggggcagg ggcagggctc caccctgcca
     2581 cacacatcct cggccagcca gcaggcctca cccgtgatcc actactcacc caccaaccag
     2641 cagcttcgcg gtgggggtca ccaggagttc cagcatatca tgtactgtga aaacttcggc
     2701 cccagctctg ccaggcctgg cccgcctccc atcaaccaag gtcagaggct gagcccgggc
     2761 gcctacccca cagtcatcca acaacagact gccccgagcc aaagagctgc caaaaacgga
     2821 cccagtgacc agaaggaagc tctgcccacg ggagtgaccg tcaaacagga acagaacctg
     2881 gaccagacct acctggatga cgagttgata gacacacacc ttagctggat acaaaacata
     2941 ttatgagacc cagtgactgg tctttgatcc gagaaatcaa agtgaaagtt aatgaaatca
     3001 tcaggaagga gttttcagga cctccctccc gaaatcagac ctagaaacaa acataatctc
     3061 gcgacgcctt ctactctgga ccgcttctgt ctcctcctgc cgtctgtgac tggaacactg
     3121 cgcatgcgca cagtgcacgc agatggtgtc agagcctggg agcctgctgc cgcgcaaaca
     3181 gcatcttagc cgttgtccat ggtgactgga cacgaaaagc aactgcctgc tgaccaaagc
     3241 ctcattctca actcaccagg atgctgaacc tgagacgcca ggctgcgctg gcaggagaac
     3301 tggagaaact gcgatagccc acagacatgg cttcattttt tttgaatttt ctctttccaa
     3361 agccaaacag ccttgccctg acaggaccac ctgtcccaac ttctcagcct taagttataa
     3421 cacacgtacg tgtctgccag cttctgggcc tttgctgtgt tttcctctgc ttcaaagagc
     3481 caaccaagga ggccgtgggc tgagagccct ctcggccagc tattccctaa cctgctgcct
     3541 acaccagact ggctggtggc atccagtccc ggctgcctgt tgggaaccct gcttctgaag
     3601 gttcccctct ccaccccctc cacccagagg tcgggagaac cttctggatc cttgcattga
     3661 ctgttaagga gctaaaacca ccaaacccag tcaaaaccta cacgtgtttg tcatgaccgc
     3721 caccaaacag aacaaagggg ccgaaatctc cctttgctct gaactcaaag caggaaagtg
     3781 ctggcttcac cctagtttgt tttttgtttt ttgtttttaa cctgaattca ggtaaagcct
     3841 ccatagactc ctgaacgctg ctgtatgagc tgtgactcag gcggatccac cccagcatat
     3901 gccttagtgt gatcaagccc tgcctggccc ggttgtgtgt cctgtgggat tctccacaca
     3961 cactgcctgc tacaggcggt cctccatggt cttcctcctg gttcagtttt cttcttccaa
     4021 cagcgtttcc cccaatcatg tacgcaagac cgtcctctcc ccttgccttc atcccagatg
     4081 tctctattgg gcatcttctt aaagtgactt tctcggcttt gtgtgctagg cagaggaccc
     4141 gagaagcaag ctacagtggc taagtacccg tggttggttt cttacgtcct ggctttcttg
     4201 tcaaagtcat ctgaaaggaa atggctggag ccgggccagc tgtcgctggt tctccttaca
     4261 gagaccccat gcccagggtt cagcttgaac atgcaaatat gactttgtgg tcaggaccta
     4321 gagtgtctcc cccttgctgc agccctgggc tttccctcca ctgaccccat gcgtagacct
     4381 gggcagaatt ctcgtgtgaa cccagaatgt ctgtaagaag ttgagcacta agccgctatg
     4441 agtctaagta cttcctgcta agcaagaaac gttctgctgg ccctttacgg ccaggagctt
     4501 ctgactggag caatgccgac ttctctgggg aagggtgatg agggttcggt gagtgacagt
     4561 tcacacttgc cctggctgag agccacgttt tgcacatgag ggagtcaggc ccttcctcag
     4621 atatctccaa gttttaccca agtgccttcc tgcaattgta gtcattgtaa ttgtagctca
     4681 gctgcactgt ccacagggag acaaagggct aactcacttc ccattagttt tcatgtcagc
     4741 gaaggggttc ctggtagctc agactcctat actttcctct gtgtgtatgt gtgcatgtgt
     4801 gtgtgtgtgt gtgtgtgtgt atatacgtgt acacaattct cttcccttta tactatctta
     4861 gccagatagt ctcagaaact tgctgataaa tatcccaaac agccaaggag agaaagcagc
     4921 atctgttacc agacaaacag gccatagaag gtgtatgagc ggcagagagc tatggagaag
     4981 gtttggtcag ttacagactc caggggaaac gtggccggga gtgactgctt atcaaccatt
     5041 tccaggatgg ggagatgcag tctgatctta gcgaatgaga aaagatgccc gagcagtgac
     5101 gacgagtgta ccgcacgtgg gttagagggg cggaagcgga aatgtgtcct tgctaaatct
     5161 gtggtgtcgt tccggtgaca gttccatatt gctaaatgtg gcactttctc ttccaagtcc
     5221 acacatctcc ctgactgtac aaaggcaccg ctgatgggga gtatatctat ctacccagat
     5281 cagtatggta ttaaatttta ttttcttatt tgtattttga tgctttttat ctgcctttaa
     5341 aatatctcac ccctgttgga gttagaacat atttataaat gaccagatgt ctttttttaa
     5401 gggtctattt ctttttttaa aaaaaatcta tatcttcatt ttctgtaaga gaaatggtat
     5461 actcctgagt tttgttttat tttgttttgt tttgttttgc tttttgtttc tcattctggg
     5521 aaacaaatcc aaagactcac ctcgggtcct atcaagacct caggatggga gagaaaggga
     5581 ctttgtagga gagaacacct tttttagctt gagaaagagg gcctgctcct tcagctccat
     5641 gtcagggctg tccctgagaa ccgtacgtga aaggtttggt tggtggtctc aatctaaagc
     5701 cacagaactc tgcctttcca tggacaagct ccttcaggca ggctgacagt tgacagagcc
     5761 aaccacgtgg agtcctcaga ggtgacactg aggtgcagca tccaaagaac agccaccttc
     5821 tccccagcgc agcgtagcca cggaccaagt gacctgggat aacactgttc acatgcagca
     5881 gcctggtcat ccattatcca gcaccaccag ccgtggccag ccgccggcag cactgtcaca
     5941 cagggaggcc agaagccagt gtgttttaat tagcactcag aacctatagg aggctgagtt
     6001 ggtttatctt cacaccacag tgctcagcat caggagaaac gggggctacg taacaactgt
     6061 gttcatttgc cgcgcttccg aaaagacaga ggtggccagg ctagggcgag tattcctgga
     6121 ctctttgccg tcagggaagg ctggaggaac ccgacacatc ctcaccactg gcatctccca
     6181 agtttggaca ccaaccttca tggacccaaa ccaggcagct gcagagcggg aggtttccct
     6241 gcagcccagc agttgcttaa atgaggcaac atcaccttca cctacgacca gcttacccgt
     6301 gccttgacag acatacggcc accatcgttg tcttaatcca gtttgtttac agctaactct
     6361 aaatggtggg ccaggagtgg tgcttccctg agcaggaccc ctctgagatc acaatgaagt
     6421 cctgggaact ggagtcaaaa gtgttaatgc tttcagatgg gaataaacgt ccctgccctg
     6481 cctggccctg cctggctctg ccctctcagg ctttagatgg actgggtgca gacagtgctg
     6541 ttgctatgtg agtaggaacc ccagcattct gtgagagcat cccagacatc agacatcccc
     6601 gtccccctgt catttctcag ccctcatggg agcctgctca tcgggctctg aaggccgggg
     6661 tttgggaaaa tctccacccc actacctgag gagtcgggat atatcacatt cctatgcaaa
     6721 acgattttaa tctccggttt cctgcagttt atttttgcta tatgtaaagt atttttatac
     6781 ggcttatatg atgacagctt agcaataaac agttgagagc aactctaaaa aaaaaaaaaa
     6841 aaaaa
//
