LOCUS       NM_001013414            5219 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus neuralized E3 ubiquitin protein ligase 4 (Neurl4),
            transcript variant 1, mRNA.
ACCESSION   NM_001013414 XM_618898
VERSION     NM_001013414.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5219)
  AUTHORS   Di Michele,M., Attina,A., Roux,P.F., Tabet,I., Laguesse,S.,
            Florido,J., Houdeville,M., Choquet,A., Encislai,B., Arena,G., De
            Blasio,C., Wendling,O., Frenois,F.X., Papon,L., Stuani,L.,
            Fuentes,M., Jahannault Talignani,C., Rousseau,M., Guegan,J.,
            Buscail,Y., Dupre,P., Michaud,H.A., Rodier,G., Bellvert,F.,
            Kulyk,H., Ferraro Peyret,C., Mathieu,H., Close,P., Rapino,F.,
            Chaveroux,C., Pirot,N., Rubio,L., Torro,A., Sorg,T., Ango,F.,
            Hirtz,C., Compan,V., Lebigot,E., Legati,A., Ghezzi,D., Nguyen,L.,
            David,A., Sardet,C., Lacroix,M. and Le Cam,L.
  TITLE     E4F1 coordinates pyruvate metabolism and the activity of the
            elongator complex to ensure translation fidelity during brain
            development
  JOURNAL   Nat Commun 16 (1), 67 (2025)
   PUBMED   39747033
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5219)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5219)
  AUTHORS   Xing,L., Simon,J.M., Ptacek,T.S., Yi,J.J., Loo,L., Mao,H.,
            Wolter,J.M., McCoy,E.S., Paranjape,S.R., Taylor-Blake,B. and
            Zylka,M.J.
  TITLE     Autism-linked UBE3A gain-of-function mutation causes interneuron
            and behavioral phenotypes when inherited maternally or paternally
            in mice
  JOURNAL   Cell Rep 42 (7), 112706 (2023)
   PUBMED   37389991
REFERENCE   4  (bases 1 to 5219)
  AUTHORS   Cardamone,M.D., Gao,Y., Kwan,J., Hayashi,V., Sheeran,M., Xu,J.,
            English,J., Orofino,J., Emili,A. and Perissi,V.
  TITLE     Neuralized-like protein 4 (NEURL4) mediates ADP-ribosylation of
            mitochondrial proteins
  JOURNAL   J Cell Biol 221 (3) (2022)
   PUBMED   35157000
REFERENCE   5  (bases 1 to 5219)
  AUTHORS   Valnegri,P., Huang,J., Yamada,T., Yang,Y., Mejia,L.A., Cho,H.Y.,
            Oldenborg,A. and Bonni,A.
  TITLE     RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the
            mammalian brain
  JOURNAL   Nat Commun 8 (1), 1271 (2017)
   PUBMED   29097665
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5219)
  AUTHORS   Imai,Y., Kobayashi,Y., Inoshita,T., Meng,H., Arano,T., Uemura,K.,
            Asano,T., Yoshimi,K., Zhang,C.L., Matsumoto,G., Ohtsuka,T.,
            Kageyama,R., Kiyonari,H., Shioi,G., Nukina,N., Hattori,N. and
            Takahashi,R.
  TITLE     The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates
            Notch Signaling through the Endosomal Pathway
  JOURNAL   PLoS Genet 11 (9), e1005503 (2015)
   PUBMED   26355680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5219)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   8  (bases 1 to 5219)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596185.12.
            
            On Nov 18, 2022 this sequence version replaced NM_001013414.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14995048.913311.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-324               AL596185.12        13507-13830
            325-769             AL596185.12        14653-15097
            770-835             AL596185.12        15299-15364
            836-1134            AL596185.12        15510-15808
            1135-1246           AL596185.12        15978-16089
            1247-1335           AL596185.12        16179-16267
            1336-1408           AL596185.12        17176-17248
            1409-1673           AL596185.12        17366-17630
            1674-1855           AL596185.12        17871-18052
            1856-1941           AL596185.12        18163-18248
            1942-2104           AL596185.12        18371-18533
            2105-2303           AL596185.12        18629-18827
            2304-2380           AL596185.12        18909-18985
            2381-2459           AL596185.12        19069-19147
            2460-2635           AL596185.12        19482-19657
            2636-2767           AL596185.12        19741-19872
            2768-2913           AL596185.12        20104-20249
            2914-3138           AL596185.12        20323-20547
            3139-3237           AL596185.12        20639-20737
            3238-3399           AL596185.12        20862-21023
            3400-3564           AL596185.12        21193-21357
            3565-3723           AL596185.12        21906-22064
            3724-3903           AL596185.12        22380-22559
            3904-3991           AL596185.12        22671-22758
            3992-4099           AL596185.12        22863-22970
            4100-4244           AL596185.12        23089-23233
            4245-4357           AL596185.12        23387-23499
            4358-4523           AL596185.12        23574-23739
            4524-5219           AL596185.12        24772-25467
FEATURES             Location/Qualifiers
     source          1..5219
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.92 cM"
     gene            1..5219
                     /gene="Neurl4"
                     /note="neuralized E3 ubiquitin protein ligase 4"
                     /db_xref="GeneID:216860"
                     /db_xref="MGI:MGI:1921092"
     exon            1..324
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..4728
                     /gene="Neurl4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     neuralized-like protein 4; neuralized homolog 4"
                     /codon_start=1
                     /product="neuralized-like protein 4 isoform 1"
                     /protein_id="NP_001013432.1"
                     /db_xref="CCDS:CCDS24921.1"
                     /db_xref="GeneID:216860"
                     /db_xref="MGI:MGI:1921092"
                     /translation="MAAGSGGSGGSGAGPGPGPGPGGGGGPGSSGPGLGSGGGLGGGG
                     ELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSG
                     SIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLVEGDR
                     VGVERTATGELRLWVNGRDCGVAATGLPARVWAVVDLYGKCTQITVLPSEPGFSPPTP
                     VPTPPLEPLAPPEDSALLEQGTSVDEAFMVSPAQARPETFPNSLDSHNDFASMELSEV
                     VSNAILSAYNGGLLNVSLSSPPAGDGLASSGPATSPILTSNDALLFHEKCGTLIKLSN
                     NNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSL
                     EYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHF
                     FINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDRLRRNNAILRALSPEGA
                     LRRAAPAAQAEPERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGE
                     VFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTIL
                     DEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQ
                     ATIVDDVEVPPVSEPLPEGNNQMSPSSPSSAAGGSDLRFHQLHGSNAVITNGGRTALR
                     HNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMT
                     DIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQG
                     AACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNTATEKSFPLHSPVAGV
                     AHRFHSMCGKNVTLEEDGTRAVRVAGYAHGLVFSTKELKAEEVFEVKVEELDEKWAGS
                     LRLGLTTLAPEDMGPGAGSGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNL
                     ERLGVGSRVGIRRCADDTMHILVDGEDMGPAAAGIAKNVWAVLDLYGPVRSVAIVSST
                     RLEEPEGTQPPSPSSDTGSEVEEDDEVEEQGLRGQNQVGIVPTALEFLENHGKNILLS
                     NGNRTATRVASYNQGIVVISQPLVPHMLVQVRIDFLNRQWTSSLVLGVITCPPERLNF
                     PASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHIN
                     GVDQGVAVPDVPQPCHALVDLYGQCEQVTIVSPDPGTASGKIAGTQGDMEKADMVDGI
                     KESVCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKRSLCYCESCRKLRGD
                     EAHRRRGEPPREYALPFGWCRFNLRVNPHLEAGTLTKKWHMAYHGSSVAVVRRVLDRG
                     ELGAGTTSILSCRPLKGEPGVGFEEPGENCAPPREEQPPPVLLSPSLQYAGAEMLASK
                     VQFRDPKSQRTHQAQVAFQVCVRPGSYTPGPPSAALRELPDQHFSPSELEWVTKEKGA
                     TLLYALLVRVE"
     exon            325..769
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            770..835
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            836..1134
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1246
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1335
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1408
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1673
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1855
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1941
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1942..2104
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2105..2303
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2304..2380
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2381..2459
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2460..2635
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2636..2767
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2913
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2914..3138
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3139..3237
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3238..3399
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3400..3564
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3565..3723
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3724..3903
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3904..3991
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            3992..4099
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            4100..4244
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            4245..4357
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            4358..4523
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     exon            4524..5219
                     /gene="Neurl4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5198..5203
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Neurl4"
                     /note="hexamer: AATAAA"
     polyA_site      5217
                     /gene="Neurl4"
                     /note="major polyA site"
ORIGIN      
        1 aagcgcggct gtcgcgcggc cgcggtatca gcggcgatgg cggcggggtc gggtgggagt
       61 gggggctctg gggcgggccc cgggccagga ccggggcccg gcgggggtgg gggccctggc
      121 agcagcggac caggcctggg gtccggcggg ggtctcggcg gtggcgggga gctgcacccg
      181 cgcaccgggc gcttggtcag cctgtcggcc tgcgggcgca cggcgcggcg gcagcagccg
      241 ggccaagagt ttaaccacgg gctggtgctg agccgagaac ccttgcgcga tggacgcgtc
      301 ttcaccgtcc gcatcgaccg caaggtcaac tcctggagtg gctccattga gattggagtg
      361 acagcactgg atcccagtgt gttggacttc ccgagcagtg ccaccgggct gaagggaggc
      421 tcctgggtag tgtcaggctg ctcagtgctg cgggacgggc gctctgtgtt ggaggaatat
      481 ggccaggacc tggaccagct tgtcgaaggg gaccgtgtgg gtgtggaacg cacagccact
      541 ggggagctcc ggctctgggt aaacgggcgg gattgtggtg tggcagccac aggcctgcct
      601 gctcgtgtct gggctgttgt ggacctttat ggcaagtgca cccagatcac tgtgctgccc
      661 tccgagccag gcttcagccc tcccactcct gtccccacac ctccccttga gcccttggcc
      721 cctccagaag attcagccct gttggaacag gggacctctg tggatgaagc cttcatggtg
      781 tccccagcgc aggcacggcc ggagacgttt cctaacagcc ttgattcgca taatgacttt
      841 gccagtatgg agctgtctga ggtggtgagc aacgccatcc tgtctgccta caatgggggc
      901 ctccttaatg tgagcctgag ctccccacca gcaggggacg gactggcatc cagtgggcca
      961 gccacttctc ccatcctcac ttccaacgat gccctgctct tccatgagaa gtgtgggacc
     1021 ctcatcaaac tcagcaacaa caataagaca gcagagcgcc ggaggcccct ggatgaattc
     1081 aacaatggag ttgtcatgac caaccgccca cttcgggata atgaaatgtt tgagatccgg
     1141 atcgacaagc ttgtagacaa gtggtctggt tccatcgaga ttggtgtcac cacccacaac
     1201 cccaatagcc tggagtaccc agccaccatg accaacctgc agtcaggcac catcatgatg
     1261 agtggctgtg ggatcctgac caacggcaaa ggcactcggc gggagtactg cgagttcagt
     1321 ctggacgagc tgcaggaggg tgaccatatt ggcctcacga ggaagtccaa ctctgcccta
     1381 cacttcttca ttaatggcat cgatcagggc gtagctactc cattgacacc accagttgta
     1441 tatggtgtag tagacttgta tggaatggca gtgaaagtga ccatcgtcca taataacaac
     1501 cacagtgacc gtctccgccg gaacaacgct atcctgaggg ctctgtcccc cgagggtgct
     1561 cttcgtcgtg ctgcccctgc agcccaggca gaacctgaac gcttgctctt ccatcctaac
     1621 tgtggccaga aggcagctat cacccacgaa ggacgcactg ccctgaggcc ccatgccact
     1681 gatgacttca atcatggcgt ggtactgagc agcagagccc tccgggatgg agaggtgttc
     1741 caggtgcgca ttgacaagat ggtggacaaa tgggctggct ccattgagat tggtgtcacc
     1801 acccataacc ctgcctacct ccagctaccc tctactatga ccaacttacg ctctgggacc
     1861 tggatgatga ctgggaatgg ggtcatgcac aatgggacaa ccatcctaga tgaatatggg
     1921 cacaacctgg accgcctcaa ggcaggggac accgtgggtg tggtgcggcg ggaggatgga
     1981 acgctccact tcttcgtcaa tgggatgact cagggccctg ctgcctggaa tgtccccccg
     2041 ggggtctatg ctgttgttga tctctacggc caggctgccc aggctactat tgtggatgac
     2101 gtggaggtgc ctccagtctc tgagccactc cctgaaggaa acaaccagat gtctcccagt
     2161 tctccatcct cagcagctgg gggctctgac cttcgcttcc accagctgca cggcagtaat
     2221 gcagtcatca ccaatggtgg ccgcactgct ctccgccaca actgccgcag cgagttcaac
     2281 gatgccattg tcatttccaa ccgagccctg cgggatggag aactgtttga aattgtcatt
     2341 cagaagatgg tagatcgttg gtcaggctcc atcgaagctg gagttactgc tattcggccg
     2401 gaagacctag aatttcccaa caccatgaca gacattgact atgatacgtg gatgctgagt
     2461 ggtacagcta tcatgcaaga tggcaatacg atgcgcaaca actatgggtg tgatctggac
     2521 gcgctgggca caggtgcacg aattggcatg atgcgaactg ccaagggtga tctgcactat
     2581 ttcattaatg gacaggacca aggcgctgcc tgctcaggct tgcctccggg taaagaggtg
     2641 tatgcagttg tggatctcta tggccagtgt gtccaagtgt ctatcaccaa tgctaccggc
     2701 cccatggaca acagcctggc caccagcaat actgccactg agaagtcatt ccccttgcat
     2761 tccccagtgg cgggtgtggc tcaccgattc catagcatgt gtggcaagaa tgtcactctg
     2821 gaggaggatg gcacacgggc agtccgtgtg gctggctacg cacatggcct cgttttcagc
     2881 accaaagagc tcaaggctga agaagttttt gaggtgaaag tggaagagct agacgagaag
     2941 tgggcaggct ccctccggct ggggctgacc acacttgcac cagaggacat ggggcctgga
     3001 gcgggcagtg gtccagggct gcctccttcc ttgcctgaac tccggacaaa gaccacctgg
     3061 atggtgtcca gctgtgaagt gaggcgtgat gggcacctcc aaaggatgaa ctatggccgg
     3121 aacctcgaga gactaggggt gggaagccgt gtgggcattc gtcggtgtgc agatgacaca
     3181 atgcacatct tggtagatgg agaagatatg gggcctgctg ccgctggcat tgccaagaat
     3241 gtgtgggctg tgttggatct gtatgggcca gtacgcagtg tggccattgt cagctccaca
     3301 aggctggagg aaccagaagg cacccagccg ccttctccca gctcagacac tggcagtgag
     3361 gtcgaggaag atgatgaggt cgaggagcag gggctgagag gccagaatca agtggggatt
     3421 gtgcccacag cccttgaatt cctggagaac catgggaaga atatcctctt atccaacggg
     3481 aaccgcacag ccactcgggt ggccagctat aaccagggca tcgttgtcat cagtcagccc
     3541 ctggtgcccc atatgcttgt tcaggtgcga atagacttcc tgaaccgaca gtggacatct
     3601 tctcttgttc tgggagttat cacctgccca cctgagaggc ttaacttccc tgcctctgct
     3661 tgtgccctta aacgggcagc ctggctcctg cggggccggg gtgtcttcca caatggtctg
     3721 aagatctgtg agaagtttgg gccaaatctt gacacctgcc ctgaaggcac catcctggga
     3781 ctgcggctag actcctctgg agggcttcat ctccacatca atggggtgga ccaaggggta
     3841 gctgtaccag atgtgcccca gccatgccat gcactggtgg acctctatgg acagtgtgag
     3901 caggtgacaa ttgtgagccc tgacccaggg actgccagtg ggaagattgc tggaactcaa
     3961 ggggacatgg aaaaagctga tatggtagac ggtatcaagg agagtgtgtg ctggggtcca
     4021 ccgcctgctg ctagcccttt aaagagctgc gagtaccatg ccctttgctc ccgcttccaa
     4081 gaactgctgt tgcttcctga agattatttc atgcctccac cgaagcgtag cttatgctac
     4141 tgtgaatctt gccggaagtt gcgaggagat gaggcccaca ggcgccgagg agagcctccc
     4201 cgggagtacg ccctgccttt cggatggtgc aggttcaacc ttagggtgaa tccccatctg
     4261 gaagctggca cactaacaaa gaagtggcac atggcatatc atggaagcag tgtagctgtt
     4321 gtgcggagag tgctggaccg aggggagttg ggagcaggta ctacctccat cctgagctgc
     4381 cgacctttga agggagagcc tggggtggga tttgaggagc ctggtgagaa ctgtgcacct
     4441 ccccgggaag agcagccccc tccagtgctg ctctccccct cccttcagta tgccggggca
     4501 gagatgctgg cctccaaagt gcaattccgg gacccaaaat cccagcggac acaccaggct
     4561 caggtggcct ttcaggtgtg tgtgcgccct ggctcctata ctcctggccc tccctctgcg
     4621 gccctcagag aacttcctga ccagcacttc agcccatcgg aacttgagtg ggtcactaag
     4681 gagaagggag ccacactcct ctatgccctg ctggtacgag tggaataagg ggtgacatac
     4741 cactactcca agcacagccg ggcctcaagc ccaggactct tgaatgacga ctgcctccac
     4801 ctcattcccg tgactgagag catgtccagt gctgtcctgg caaggaggag cacgtaggca
     4861 ggctttgatt tagagcaggt gtgaagcaca tctctacatt cagggcccag cacactccct
     4921 ctgctgagag ggagcccagc tcgtctcggg gtcccccctt catgcactga cttggggaac
     4981 atgactccct attattaccc tcccccatat cacttaattt atttccgttt ttgtttctgg
     5041 ttactgtgaa tcccaaagga gtctctctgt gcccacatga agctgctttt tccgtggcca
     5101 ctgggcgcca tggggaggga gtgggtaaaa ggaagggctg cccgaggacg ctgtgggcct
     5161 ctgtacagtt gttactgact ctgatttcta aggagccaat aaatactgtc ttcagagca
//
