LOCUS       NM_144946               7089 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus neuropilin (NRP) and tolloid (TLL)-like 1 (Neto1),
            transcript variant 1, mRNA.
ACCESSION   NM_144946
VERSION     NM_144946.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7089)
  AUTHORS   Greene,S.M., Klein,P.R., Alcala,G.A., Bustamante,I., Bordas,B.,
            Johnson,A., Vu,V., Uhm,S.Y. and Gould,G.G.
  TITLE     Aging to 24 months increased C57BL/6J mouse social sniffing and
            hippocampal Neto1 levels, and impaired female spatial learning
  JOURNAL   Behav Processes 211, 104929 (2023)
   PUBMED   37586617
  REMARK    GeneRIF: Aging to 24 months increased C57BL/6J mouse social
            sniffing and hippocampal Neto1 levels, and impaired female spatial
            learning.
REFERENCE   2  (bases 1 to 7089)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7089)
  AUTHORS   Li,Y.J., Duan,G.F., Sun,J.H., Wu,D., Ye,C., Zang,Y.Y., Chen,G.Q.,
            Shi,Y.Y., Wang,J., Zhang,W. and Shi,Y.S.
  TITLE     Neto proteins regulate gating of the kainate-type glutamate
            receptor GluK2 through two binding sites
  JOURNAL   J Biol Chem 294 (47), 17889-17902 (2019)
   PUBMED   31628192
  REMARK    GeneRIF: Neto1 and Neto2 differentially regulate GluK2 fast gating
            kinetics
REFERENCE   4  (bases 1 to 7089)
  AUTHORS   Tenney,A.P., Livet,J., Belton,T., Prochazkova,M., Pearson,E.M.,
            Whitman,M.C., Kulkarni,A.B., Engle,E.C. and Henderson,C.E.
  TITLE     Etv1 Controls the Establishment of Non-overlapping Motor
            Innervation of Neighboring Facial Muscles during Development
  JOURNAL   Cell Rep 29 (2), 437-452 (2019)
   PUBMED   31597102
REFERENCE   5  (bases 1 to 7089)
  AUTHORS   Copits,B.A., Robbins,J.S., Frausto,S. and Swanson,G.T.
  TITLE     Synaptic targeting and functional modulation of GluK1 kainate
            receptors by the auxiliary neuropilin and tolloid-like (NETO)
            proteins
  JOURNAL   J Neurosci 31 (20), 7334-7340 (2011)
   PUBMED   21593317
  REMARK    GeneRIF: Assembly with NETO1 and NETO2 differentially modifies
            homomeric glutamate K1 (GluK1) kainate receptor gating.
REFERENCE   6  (bases 1 to 7089)
  AUTHORS   Ng,D., Pitcher,G.M., Szilard,R.K., Sertie,A., Kanisek,M.,
            Clapcote,S.J., Lipina,T., Kalia,L.V., Joo,D., McKerlie,C.,
            Cortez,M., Roder,J.C., Salter,M.W. and McInnes,R.R.
  TITLE     Neto1 is a novel CUB-domain NMDA receptor-interacting protein
            required for synaptic plasticity and learning
  JOURNAL   PLoS Biol 7 (2), e41 (2009)
   PUBMED   19243221
  REMARK    GeneRIF: Neto1 regulates NMDA receptor-dependent synaptic
            plasticity and cognition.
REFERENCE   7  (bases 1 to 7089)
  AUTHORS   Fernandez,E., Collins,M.O., Uren,R.T., Kopanitsa,M.V.,
            Komiyama,N.H., Croning,M.D., Zografos,L., Armstrong,J.D.,
            Choudhary,J.S. and Grant,S.G.
  TITLE     Targeted tandem affinity purification of PSD-95 recovers core
            postsynaptic complexes and schizophrenia susceptibility proteins
  JOURNAL   Mol Syst Biol 5, 269 (2009)
   PUBMED   19455133
REFERENCE   8  (bases 1 to 7089)
  AUTHORS   Michishita,M., Ikeda,T., Nakashiba,T., Ogawa,M., Tashiro,K.,
            Honjo,T., Doi,K., Itohara,S. and Endo,S.
  TITLE     Expression of Btcl2, a novel member of Btcl gene family, during
            development of the central nervous system
  JOURNAL   Brain Res Dev Brain Res 153 (1), 135-142 (2004)
   PUBMED   15464227
REFERENCE   9  (bases 1 to 7089)
  AUTHORS   Michishita,M., Ikeda,T., Nakashiba,T., Ogawa,M., Tashiro,K.,
            Honjo,T., Doi,K., Itohara,S. and Endo,S.
  TITLE     A novel gene, Btcl1, encoding CUB and LDLa domains is expressed in
            restricted areas of mouse brain
  JOURNAL   Biochem Biophys Res Commun 306 (3), 680-686 (2003)
   PUBMED   12810072
  REMARK    GeneRIF: Data describe the isolation and characterization of a
            novel gene, Btcl1 (brain-specific transmembrane protein containing
            two CUB and an LDLa domains), which has significant homology with
            neuropilin-1 and -2 in their CUB domains. [Btcl1]
REFERENCE   10 (bases 1 to 7089)
  AUTHORS   Stohr,H., Berger,C., Frohlich,S. and Weber,B.H.
  TITLE     A novel gene encoding a putative transmembrane protein with two
            extracellular CUB domains and a low-density lipoprotein class A
            module: isolation of alternatively spliced isoforms in retina and
            brain
  JOURNAL   Gene 286 (2), 223-231 (2002)
   PUBMED   11943477
  REMARK    GeneRIF: Focuses mainly on human NETO1 but also describes
            identification of mouse Neto1.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113599.10.
            
            On Feb 17, 2018 this sequence version replaced NM_144946.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK081325.1, AK043710.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-959               AC113599.10        61535-62493
            960-1013            AC113599.10        64541-64594
            1014-1151           AC113599.10        64835-64972
            1152-1400           AC113599.10        71223-71471
            1401-1442           AC113599.10        127625-127666
            1443-1570           AC113599.10        127783-127910
            1571-1799           AC113599.10        140198-140426
            1800-1913           AC113599.10        161333-161446
            1914-2472           AC113599.10        165125-165683
            2473-2546           AC113599.10        166596-166669
            2547-7089           AC113599.10        167496-172038
FEATURES             Location/Qualifiers
     source          1..7089
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 58.47 cM"
     gene            1..7089
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /note="neuropilin (NRP) and tolloid (TLL)-like 1"
                     /db_xref="GeneID:246317"
                     /db_xref="MGI:MGI:2180216"
     exon            1..959
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             932..2533
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; neuropilin and tolloid-like protein 1;
                     brain-specific transmembrane protein containing 2 CUB and
                     1 LDL-receptor class A domains protein 1"
                     /codon_start=1
                     /product="neuropilin and tolloid-like protein 1 isoform 1
                     precursor"
                     /protein_id="NP_659195.3"
                     /db_xref="CCDS:CCDS29387.1"
                     /db_xref="GeneID:246317"
                     /db_xref="MGI:MGI:2180216"
                     /translation="MIYGRSLFHIIASLIILHSSGATKKGTEKQITPETQKSVQCGTW
                     TKHAEGGVFTSPNYPSKYPPDRECVYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIE
                     VRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDF
                     KDLGVLKPLPACEFEMGGPEGIVESIQILKEGKASASEAVDCKWYIRAPPRSKIYLRF
                     LDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSR
                     NSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSL
                     LDQLTNTSGTVIGVTSCIVIILIIVSVIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPH
                     YELCTLRGTGATADFADVAEDFENYHKLRRSSSKCIHDHHCGSQLSSAKGSRSNLSTR
                     DASILAEIPTQPVKPLIPPVNRRNILVMKHNYSQDAADACDIDEIEEVPTTSHRLSRH
                     EKSVQRFCLIGSLSKHESEYNTTRV"
     exon            960..1013
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1151
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1400
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1442
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1443..1570
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1799
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1913
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2472
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2546
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2547..7089
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3509..3514
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /note="hexamer: TATAAA"
     polyA_site      3533
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /note="major polyA site"
     regulatory      3698..3703
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3728
                     /gene="Neto1"
                     /gene_synonym="Btcl1; C130005O10Rik"
                     /note="major polyA site"
ORIGIN      
        1 gccgccccat tccgccgcgc accagccctg ggggcaccgg ctgtgctcag ctgcccagtc
       61 tcacccaggc ttcaggcttc ctggagggtc atgcaaccta tagctatgat taagactctc
      121 acttggtaac tctgccatat tccttatctt tccccccctt ccctcccctc cccctttaac
      181 cacccccgtg ttcccctcca ccacccttga gccctccccc gcccccagac gcccaccctt
      241 agactccttt tcctgcaaga tcgcagaggt ggcgcgcagc ccgacgagcc gatgacggac
      301 ccctgcctcc cgccttcaat gcctcagcag aagaccccca aaggctggag agaggagggc
      361 tgcggctgga catcctccgg gcgacgctgc tcggacctgg tgctagtggt ggatgagact
      421 ggcgactgaa caagtccctg cctctgactt cgctgtcgtc tgcccagtcg ttgccgtcga
      481 tccggaccgg tccccacctt gcgccttctg cctctcacac cagatcgggt cccggcttcg
      541 ggcgccccgg ggctcgcccc gcgcctgccg ccgcccgcgc gccgactgcc cgccgcgtcc
      601 tcctgacagc tgcggcggcg gtgatgcaga ggaggagggc gctgccggcg gcggtgctca
      661 tggtggcggt cggcgcccgg gtgtaatgcg agcgtcatgg tggagatgct ggcttcgcgg
      721 cggtgagaga gcaaaggagg gcgagagtca gccaagggcg gaagacaaac cagttccgat
      781 gctttctttc ctctgtcgct ttcccccact ctattttacc cgtggtttgc atatttaaaa
      841 tctctggact caatcctctc cctaccaccg aagtctcccc gcttctaaat ggaattagtg
      901 gagatcggag cctctggtgt aacgcacaga catgatctat ggacgcagtt tgtttcacat
      961 tatagcaagt ttaatcatcc tccattcttc tggagcaacc aagaaaggaa cagaaaaaca
     1021 aatcacccca gaaacacaga agtcagtgca gtgtggaacg tggacaaagc atgcagaggg
     1081 aggtgtcttt acgtctccca attatcccag caaatatccc ccagaccgag agtgtgtcta
     1141 catcatagaa gctgccccaa ggcagtgcat tgaactttac tttgatgaaa aatactcaat
     1201 cgaaccatct tgggagtgca aatttgatca tattgaagtt cgagatggac cctttggctt
     1261 ttctccaata attggaaggt tctgtggaca acagaatcca cctgtaataa aatctagtgg
     1321 aagatttctg tggattaaat tttttgctga tggcgagctg gagtctatgg gattttcagc
     1381 tcgatataat ttcacacctg atcccgactt taaggacctt ggagttttga aaccattgcc
     1441 agcgtgtgag tttgagatgg gcggcccgga aggaattgtg gagtccatac agattctgaa
     1501 ggaaggcaaa gcttctgcca gtgaagccgt ggattgcaaa tggtacatcc gagccccacc
     1561 acgatccaag atttacttac gtttcttgga ctatgagatg cagaattcaa atgagtgcaa
     1621 aagaaacttt gtggcggtct atgacggaag cagctccgtg gaggatttga aggccaagtt
     1681 ctgcagcaca gtggctaatg acgtcatgct gcgcacaggc cttggggtga tccgcatgtg
     1741 ggcagacgag ggtagccgta acagcaggtt tcagatgctc ttcacatcct ttcaagaacc
     1801 tccctgtgaa ggcaacacat tcttctgcca cagtaacatg tgtattaaca acacgctagt
     1861 ctgcaatggg ctccagaact gtgtatatcc ctgggatgaa aatcactgta aagaaaagag
     1921 gaaaaccagc ctgctggatc agctgaccaa caccagtggg acggtcattg gcgtgacttc
     1981 ctgcattgtg atcatcctta ttatcgtttc tgtcattgta cagatcaaac agcctcgtaa
     2041 aaaatacgtc caaaggaagt cagactttga ccagaccgtt ttccaggagg tgtttgagcc
     2101 tccccactat gagttatgta cgctcagagg aactggagca acagccgact ttgcagacgt
     2161 ggcggaagac tttgaaaatt accataaact gaggagatca tcttccaaat gcatccatga
     2221 ccatcactgt ggatcccaac tgtccagcgc gaaaggcagt cgcagtaacc tcagcacaag
     2281 ggacgcttcc attttggcag agatacccac acagccagtc aagcccctca tcccacccgt
     2341 gaacagaagg aacatcctgg tcatgaaaca caactactca caagatgccg ccgatgcctg
     2401 tgacatcgac gagattgagg aggtgcccac cacaagccac aggctatcca gacacgaaaa
     2461 atctgtccag cggttctgcc tcattgggtc tctaagcaaa catgaatctg aatacaacac
     2521 aactagggtc taaacgaaaa ttcaagagaa gaactattta tacaaacatg gggactgtga
     2581 aaagaaaatt ccgtagtgaa ttgtgaaaag tggacatatt tctaaattca ttccactgcc
     2641 tttatccaaa cttaagagtt gcagacatgt gttattcctt cggcaagact ccctgctgct
     2701 gcacaatgat gtgtccattt cctaatttgg ttgctgatca ccaagtgctc cttaggtttt
     2761 aaatacattc tgagatttac ggaaacttga agaagaaatt agttcctgat tgagactacc
     2821 ccagctttat gtttactgtc gttttcacat tatttatatg ttgtttacgt gtctttgtta
     2881 catgattgta cttatgtgat ttgtgggaaa agaaaaaaaa aaaccacaac tttgggtgaa
     2941 ccttgtgtta catgtccatt gttttcatta tatagactgc ttgaaaatag tgcattcctg
     3001 cgtgattttg agcaagcttc agtgaaaaat gctaaagtgg accatgaaaa caccatctag
     3061 aggctcaatg gactgtacac acctgttgtt ttattataat taaatttagt aaaacataat
     3121 gagtaaaatc tagattgcaa taagacaaat ctctctctcc ccctctctgt cgttatcttt
     3181 gtcctccgcc cttattgttt ctatgtaccc ctgctttcct ttttgttttt accaagggaa
     3241 gataccgagt ttcacaaatg gctttttgaa atcaggtatt ttaccattca aactctacaa
     3301 cagaatttcg tttgattaag cacttagcaa tatgactgaa ctgacagttt gagaaaatac
     3361 cctgcatgtc agtactggat atttaggttg gaaaaaaatg ccctctttct tagacacatt
     3421 gtaaaaagca tgcattctca aatactgctg ttactgttcc atttctttgt gtcatatgct
     3481 tgctacttgt aacttttata taaatatata taaaatgtat aataatttcc taatttgagt
     3541 taagagaatt gtttcttcta ctgtgataaa aagcagagtt acctaagtac atgatttgtt
     3601 actttcaaca ctctctaggt tacaggatgc catttgatac tgaggcttac ttccctacat
     3661 atttgattat taacatctta caagtatctt cttttatatt aaaagtctct ctaagtcaat
     3721 ccttaaaagt catagaccat tttatgactg aactgtaacc ttctgagtta cttcttaccc
     3781 atacacacct atacctgaat gcttaatggt tgcagtaagt ttcatacaga aaaactaaaa
     3841 cccttatatc acacagaagt tctgttgaat tatattcatc ctcataaaca ctaaatggat
     3901 acctttttaa ataaaaaaat gtactcttaa acaattaaat ttaaagttac atttacagta
     3961 agcccgttta ctactttcaa aatagccaaa ttctcaataa taaaaccagg aacttcaaat
     4021 agcaaagaaa tctagtctaa gacaacagcc ggagaagcat ttacaatcta aatggatatt
     4081 cctgtcatat ggccctaata ggaggccaat ccagtatata ttacagtata aataaaagaa
     4141 aacatcaaca agtaaacaga gataaagtaa attgtaatag aaaacactaa ctaaaaaata
     4201 cagcaattct tgaatattgg aaacattatc aaggtacttt gtggggtact tgcagcacac
     4261 ggacaggagt actcggtggc caacctgtaa ttacagctat atgaagacag agaagggcaa
     4321 acaatttaac taaatgagct gaaagagaga agcctgaact caacaagagc cccttcctta
     4381 gcaaacagtg gaaactgagt gaagacgatg ctcagtgtgg acttctggcc tacacacaca
     4441 cacacacaca cacacacaca cacacacgct cataaaaaga aaatagcata caaaggatca
     4501 ttctttgagt taatttaaca aattgtccca gaagaaaatg tactgacata atgaatatca
     4561 tctttcttta gcatgatact tacacatatc ttgataaaaa ttcaccttta cccactgtgc
     4621 tagacaaatt atttgttacc acatataatg ttgtgcccat taattaaaag ttggcactcc
     4681 agattatcat tcaacttagt tctactattt tgggttatgt catctcttta ggggtcctca
     4741 ttggacatta ttaactttga atgaacaatc tcaaagactt gatatatgtg tccctgtgtg
     4801 tttcattaca caacaatgaa gacaactaaa ttgagtagat acatcaccat gcacctgtca
     4861 tgtagattta caggtttttc caattttttt gcagatctat aaaatcctgc aaatccgctt
     4921 attctatgct gaaaggtatt tatgcctcaa acccactaag tggatacctt cttttttgac
     4981 attaaagtga attaagtata aatttaagga tggatgactc acatgtattt gattatgatt
     5041 actccatggg aaaaataatc ccttttagaa gatgtacatc attatggatg atgatcaatc
     5101 aacttacaga tattgacttg tcgatagggg agatgctagg atcactttcc agagtccttg
     5161 aggcctgtga ttgttcctat tagagatgct atattgtaat ccagatgtgg gagtcaagaa
     5221 aaggattcaa ttatatattg gaactcccta caggtgcctt cataaagtcc aatattgaga
     5281 tttttgacat taaaaataaa tattaactac atcagacgtt tttggtttaa tataaacctt
     5341 tggacaatct tttaaaaatg cgtaacactt gtagtagaaa gaagtgttca aaaccatcaa
     5401 acaagtttat caattaatat tttattcaca aagtgaattt aaataaacta gcataagagc
     5461 tatattgatt caatgagctc cttttaaata catcactatg taaatttgtt gattcattct
     5521 ttagaatctt ggtggtagcc catgttacat gaaataccca cgtcagcttg agtttagctt
     5581 tgcaattctg tccaagggca gtgcaattgc tcaacacaag gttgatgttc tgatgtctaa
     5641 ttcttgattt tttttctgta cctgttttta taaacatgca tattttatgc ataatttcac
     5701 aaagtagacc tgatatttga tttgccataa cttaatttag tcatgtaatt aaaatatgca
     5761 gtaagcataa ctggagatca atgtcacaag gtccttagag gagagtcagc cctgtcctag
     5821 agatgcggat tcttttacct actttttgtt ctattgagaa tatttaagag cattgagtag
     5881 actcacaatt ctgcctccca acattttaag tttgttcttt tgcattatgt gaatattctc
     5941 ttaagctttg cattagcttc ctctgtatcc cccaaaggaa gtcaagattt tcttacaata
     6001 caggttttgc ttcttttatt tttagatcaa gaatggattt tcatggacta aaagtattga
     6061 aataagttgg ataatattgt tctgagtctt atcacctttg agtagcaaca acaaactgca
     6121 tcattttttt gatagtcaaa taaatgatac tatccagttt gaatgatagt aattctcaat
     6181 tctgtaggga agtgaaataa ataaatgatt taaaattcat ctgaattcta aatggatatg
     6241 atagagactg taagattttt catctaatga gcacaagggt tagttgctat gcatacattc
     6301 ctccattaaa caatatttat cactgcttga tgagatagat gcagacaaaa tatcatcaag
     6361 tagttaaaag aatatgataa atggaacttg agttaattag ttgttcttta tttctttagt
     6421 taatattcct tatattccct ttaaaaaatt ggagaaaaaa aactacatat caattttttt
     6481 cttaaaaaat gtcttttaat cacttataca actcaataat tccaaagcaa cttttaattt
     6541 agaattgtaa ctattcatct tgtaatgaat ttagattgtt ctaaaattta actaaatcat
     6601 attatttgag taaacctaac agagaaacaa agggaagaaa taagtaagta atgtcaggaa
     6661 cacaatttag gactttcccc gggtaccaaa ctgtgtgctt tctgttgttt tcctaaggag
     6721 ggacatgctt ttctctaaca tcccttcatt tccttatgtc aggaaacaaa tgcaaaagca
     6781 agcttcatca agcttctgtc atttgcttgg agcatttgga gaagttttgt attcatgtga
     6841 accagcatga gcataccatc ggttgctttt ctctttggga atcattacag ttgtgcagcc
     6901 agcacattct ttgtccctat catctttctc tcttcaactg ctgagccatg ctattttcca
     6961 gccattcatt gaaaaattgt ttgggggtgt ctcttgctac tcaccaatac tcaagcaaaa
     7021 attacatctg accaggacgt atgatgtgta agttatttaa aataaaatta ttccttttgt
     7081 atcacatta
//
