LOCUS       NM_001394992            8865 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus NIMA (never in mitosis gene a)- related kinase 10
            (Nek10), transcript variant 2, mRNA.
ACCESSION   NM_001394992
VERSION     NM_001394992.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8865)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8865)
  AUTHORS   You,L., Yan,K., Zou,J., Zhao,H., Bertos,N.R., Park,M., Wang,E. and
            Yang,X.J.
  TITLE     The chromatin regulator Brpf1 regulates embryo development and cell
            proliferation
  JOURNAL   J Biol Chem 290 (18), 11349-11364 (2015)
   PUBMED   25773539
REFERENCE   3  (bases 1 to 8865)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 8865)
  AUTHORS   Church,D.M., Goodstadt,L., Hillier,L.W., Zody,M.C., Goldstein,S.,
            She,X., Bult,C.J., Agarwala,R., Cherry,J.L., DiCuccio,M.,
            Hlavina,W., Kapustin,Y., Meric,P., Maglott,D., Birtle,Z.,
            Marques,A.C., Graves,T., Zhou,S., Teague,B., Potamousis,K.,
            Churas,C., Place,M., Herschleb,J., Runnheim,R., Forrest,D.,
            Amos-Landgraf,J., Schwartz,D.C., Cheng,Z., Lindblad-Toh,K.,
            Eichler,E.E. and Ponting,C.P.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129580.14 and AC117608.13.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AC129580.14        106537-106628
            93-200              AC129580.14        123176-123283
            201-261             AC129580.14        123505-123565
            262-392             AC129580.14        129334-129464
            393-491             AC129580.14        130841-130939
            492-576             AC129580.14        138541-138625
            577-618             AC129580.14        142961-143002
            619-697             AC129580.14        145184-145262
            698-765             AC129580.14        146245-146312
            766-845             AC129580.14        147896-147975
            846-932             AC129580.14        149003-149089
            933-1157            AC129580.14        153158-153382
            1158-1297           AC129580.14        156242-156381
            1298-1359           AC129580.14        158074-158135
            1360-1437           AC129580.14        160181-160258
            1438-1502           AC129580.14        161693-161757
            1503-1605           AC129580.14        163137-163239
            1606-1734           AC129580.14        163324-163452
            1735-1872           AC129580.14        163949-164086
            1873-1918           AC129580.14        165854-165899
            1919-2040           AC129580.14        167791-167912
            2041-2143           AC129580.14        168031-168133
            2144-2219           AC117608.13        51533-51608
            2220-2349           AC117608.13        97055-97184
            2350-2420           AC117608.13        97730-97800
            2421-2634           AC117608.13        104054-104267
            2635-2818           AC117608.13        121975-122158
            2819-2905           AC117608.13        122251-122337
            2906-2960           AC117608.13        124031-124085
            2961-2998           AC117608.13        135955-135992
            2999-3031           AC117608.13        145336-145368
            3032-3132           AC117608.13        146995-147095
            3133-3243           AC117608.13        153147-153257
            3244-3352           AC117608.13        165564-165672
            3353-3405           AC117608.13        167492-167544
            3406-3461           AC117608.13        167625-167680
            3462-8865           AC117608.13        173125-178528
FEATURES             Location/Qualifiers
     source          1..8865
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 7.08 cM"
     gene            1..8865
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /note="NIMA (never in mitosis gene a)- related kinase 10"
                     /db_xref="GeneID:674895"
                     /db_xref="MGI:MGI:2685128"
     exon            1..92
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            93..200
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..3510
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /EC_number="2.7.11.1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     nimA-related protein kinase 10; never in mitosis A-related
                     kinase 10; serine/threonine-protein kinase Nek10"
                     /codon_start=1
                     /product="serine/threonine-protein kinase Nek10 isoform 2"
                     /protein_id="NP_001381921.1"
                     /db_xref="GeneID:674895"
                     /db_xref="MGI:MGI:2685128"
                     /translation="MPDQDTKAKSTEKTADKQQGTTTRDYSDLKRLRCLLNVQSSKQQ
                     LPAINFDSAQNNMTKSEPTIRTGGHRARGQWHESTEAVELENFSINYKNERNFSKHPQ
                     HQLFQEIFTALVRNRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGIED
                     LAQYMEIVANEYLGYAEEQHCVDKLVNMTYIFQKLAAVKDQREWVTASGAHKTLVSLL
                     GARDTTVLLGALLALASLAESSECREKISELNVVENLLMILHEYDLLSKRLTAELLRL
                     LCAEPQIKEQVKLYEGIPILLSLLHSDHLKLLWSVIWILVQVCEDPETSVEIRIWGGI
                     KQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIEENTVSLQAACC
                     AALTELALNDTNAHQVVQENGVYTIAKLILPNKQSNAAQTNLLQCYAFRTLRFLFSME
                     RNRPLFKRLFPTDLFETFIDIGHYVRDIGAYKDLVSQLNLLLEDELKQIAENIESINQ
                     KKAPLKYIGDYAVLDHLGSGAFGCVYKVRKRSGQNLLAMKEVNLHNPAFGKDKKDRDS
                     SVKNIVSELTIIKEQLYHPNVVRYYKTFLENDRLYIVMELIEGAPLGEHFNSLKEKHH
                     HFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDFGLAKQKQE
                     SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAAGCILYQMATLSPPFCSTNMLSLATK
                     IVEAVYEPVPEGIYSEKVTDTIRRCLTPDAEARPDIVEVSSMISDVMMKYLDRLSTSQ
                     LALERKLERERRRTQRYFMEANRNAVTCHHELALLSQETFEKASLSSSSSGAASLKSE
                     LSESAELPGEGCHIPCGKEEDRVCEEVLSEDNFQLESVEKDLYSELDDELDVSDNCSS
                     SSSSPLKESTFSILKRSFSASGRERHSQARDFIAGLGSRPRPGPQMSTFVVESASAGI
                     AVSQRKVRQICDPIQQILIQLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPC
                     NLKSEIKKLSQGSPEPIELNFLTSDYHSLRHSRAANNWSPSDPTGSPSSFEVEEGVTY
                     EQMQTVIEEVLEESGYYNFTTKRCHSFPWVTKSYTAKR"
     exon            201..261
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            262..392
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            393..491
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            492..576
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            577..618
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            619..697
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            698..765
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            766..845
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            846..932
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1157
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1297
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1359
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1437
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1502
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1605
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1734
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1872
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..1918
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2040
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2143
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2144..2219
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2220..2349
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2350..2420
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2421..2634
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2635..2818
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2819..2905
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..2960
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2961..2998
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            2999..3031
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            3032..3132
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            3133..3243
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            3244..3352
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            3353..3405
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            3406..3461
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     exon            3462..8865
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6546..6551
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /note="hexamer: ATTAAA"
     polyA_site      6567
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /note="major polyA site"
     regulatory      8126..8131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /note="hexamer: AATAAA"
     polyA_site      8147
                     /gene="Nek10"
                     /gene_synonym="Gm282"
     regulatory      8843..8848
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nek10"
                     /gene_synonym="Gm282"
                     /note="hexamer: AATAAA"
     polyA_site      8865
                     /gene="Nek10"
                     /gene_synonym="Gm282"
ORIGIN      
        1 agactggagc tggtttgagc ttgtagggag gattctgcag caagaggagg aagacttgag
       61 gctggcctga aagagggccg ccctcctgcg cggaatgcaa tgttaattct gaggtgttga
      121 tgttttacaa tgcccgatca agatacaaag gcgaagagca cagagaaaac cgctgataag
      181 caacaaggga ccaccaccag ggactattca gatcttaaaa gacttcggtg cctgttgaac
      241 gttcagtcaa gcaaacagca gcttccagcc attaactttg acagtgccca aaataacatg
      301 acaaagtctg agccaaccat caggacaggg ggacatagag ctcgtggtca atggcatgag
      361 tccacagaag cagttgaact tgaaaatttt agtataaact ataagaatga aaggaatttc
      421 agcaaacatc cacagcatca gttatttcaa gagatcttca cagctctggt gagaaacaga
      481 cttatatgca gagagtgggt taatcgtgct ccatccattc attttctgag agtgttaatt
      541 tgtctgaggc tgctgatgcg ggatccatgt tatcaggaaa tactccataa attgggtggt
      601 attgaagacc ttgctcagta catggagatc gtggccaacg agtacctggg ctacgctgag
      661 gagcagcact gtgtggacaa gctggtcaat atgacgtata tttttcaaaa acttgctgct
      721 gtgaaagacc aaagagaatg ggttactgca agtggagccc acaagacatt agtgagtttg
      781 cttggtgccc gagacaccac tgtcctcttg ggtgctctgc tggcactggc cagcttagca
      841 gagagttcag agtgtaggga gaagatcagt gaactcaacg tagtagaaaa tctgttgatg
      901 attctgcacg aatatgattt actctccaaa agactcactg ccgagctcct gcgcctgctt
      961 tgtgctgagc cccagatcaa ggagcaggtg aaactctatg aagggatccc catcctgctc
     1021 agtctgcttc attctgatca cttgaagctg ctgtggagtg tgatctggat tctggtccag
     1081 gtgtgtgagg acccggagac tagtgtggaa atccgaatct ggggtggcat caagcagctc
     1141 cttcatattt tacaaggaga cagaaatttt gtttctgacc gttcttccat cggaagcctg
     1201 tccagtgcaa atgccgcagg acgcatccag cagcttcatt tgtcagaaga tttaagccct
     1261 ggggaaatcg aggaaaatac tgtctctctc caagcagcct gctgtgctgc cctcaccgag
     1321 ctggccctca atgataccaa tgcccaccaa gtggtacagg aaaatggtgt atatacaata
     1381 gcaaaattaa ttttaccaaa taaacaatcg aatgcagcac aaactaatct actacagtgt
     1441 tatgctttca gaaccctgag gtttctcttc agtatggaaa ggaacaggcc actctttaaa
     1501 agactttttc ccaccgacct gtttgagacc ttcattgaca taggacatta cgttcgtgat
     1561 attggtgctt ataaggactt ggtatcacag ttgaatttac tattggaaga tgagctgaag
     1621 caaattgctg agaatattga aagcatcaat cagaagaaag cgcccttgaa gtacataggt
     1681 gactatgctg tgttggacca ccttggaagt ggagcttttg gctgtgttta taaggttaga
     1741 aagcgtagtg gtcaaaatct tttagcaatg aaggaggtca atttgcataa cccagcattt
     1801 ggaaaggata agaaagaccg agacagcagt gtcaagaaca ttgtttctga attaacaata
     1861 attaaggagc agctttatca tcccaatgtt gtacgttatt ataaaacatt tttggaaaat
     1921 gacaggttgt atatcgttat ggagctgata gaaggagccc cacttggaga gcactttaat
     1981 tctttgaagg aaaaacatca ccatttcagt gaagagcgac tgtggaaaat atttatacag
     2041 ctgtgcttag ctcttcggta tctgcacaag gagaagagga ttgttcacag agatctcacg
     2101 ccaaacaaca ttatgctggg agataaggac aaagtgacag ttactgactt tggcctggca
     2161 aagcaaaaac aggaaagcag taagcttaca tctatggtgg gaacgatcct ctattcttgc
     2221 ccagaggtcc tgaagagtga gccatatgga gagaaggccg atgtctgggc tgctggctgc
     2281 atcctttatc agatggcgac tctaagtcct cccttctgta gcaccaacat gctctccttg
     2341 gctactaaaa tagtggaggc tgtatatgag ccagtgccag aaggtatcta ctctgaaaaa
     2401 gtgacagata ccattagaag gtgcctcact cctgatgcag aagcccgtcc agatattgta
     2461 gaagttagtt ccatgatatc agatgtcatg atgaagtatt tagacagatt atccacatcc
     2521 cagctagcct tggagaggaa actggaaagg gagcggaggc gcacacagag atactttatg
     2581 gaagccaaca ggaatgctgt cacatgtcac catgagctgg ctcttctgtc ccaggagacc
     2641 tttgagaagg caagcctgag cagcagtagc agcggggcag ccagcctgaa aagtgagctt
     2701 tcagagagcg cagagctgcc tggagagggc tgccacatcc cctgcgggaa ggaggaggac
     2761 agggtctgtg aggaggtgct gtcagaagac aacttccagc tggagagtgt ggagaaagac
     2821 ctgtattctg agctagacga tgagctggac gtctcggaca actgtagcag ctccagttca
     2881 agccccctaa aggagtctac attcagcatt ttaaagcgaa gtttcagtgc ttcgggaaga
     2941 gaaaggcact cacaggcaag ggacttcatt gctggactag gatcaagacc aagaccaggg
     3001 ccacagatga gcacctttgt ggtagagtca gcatctgcag gcatcgctgt atcccagcgg
     3061 aaagtgcggc agatctgcga ccccattcag cagatcctga tccagctaca taaagttatc
     3121 tacatcacgc agctccctcc agctctgcac catgatctga agagaagggt tatagagaga
     3181 ttcaagaagt ccctgttcag tcagcagagc aacccatgta acctgaaatc tgaaattaag
     3241 aagttgtctc aggggtctcc agaacccatc gagctgaact ttcttacctc agattatcat
     3301 tcacttcgcc attcacgagc tgcaaacaac tggtccccaa gtgaccccac aggttcaccc
     3361 agcagctttg aagtggaaga gggagtcaca tatgagcaga tgcagactgt gattgaagaa
     3421 gtcctagagg aaagtggcta ttacaacttt acaactaaga ggtgtcactc ttttccatgg
     3481 gtgaccaaga gctacacagc caaaagatga gagccctgca ttggaaaaaa tggagtttcc
     3541 cagtcaagtt caagttccgg tgggcttcaa ctgtgacatg acagcaagat gcccagaaca
     3601 gcacaggaaa gagccatgat gctgccggag tgttcttata gtcctgtgga ggtgtgaggc
     3661 aaccccagtg ctgggctcta ttcccagtgt gcattgcatg cacaataaca ggctatcagt
     3721 gtacttctgg gagaaaacat ggcaaaatgg ctaccaggac tggggtggag tggcagcagc
     3781 acagaatttc cctagaggtt aaatgactta tatttttcaa aggaacattt tatactcaag
     3841 atagctggaa ctatgcttaa aagtatgttg tcttccatgt acacagaata gttttagata
     3901 aaataattac aggaccctgt gcaacatatt aggtattcca ttgggttccc attttttaat
     3961 cttaaaagaa attcagaaca tggtagttta taaattaaat gactggttct ctctgatcca
     4021 cttgggtgct agaggttctg aaacatgaca cagtgtagac agtatttgta accttgcaca
     4081 caagttttcg agtttgaata cccagatcgc acctagacta gtaaagtcta ttgctataca
     4141 atatgtgtat atggcatatg tccagtgatg gagggaggct tgcttaggct ggtgcttgct
     4201 gctaatcaag cttgctgtgt ttctaaaaca cattaaagaa gctatagact atgaaagaga
     4261 taacagttct tattctagac cttactgaat cacctgtgtg taagacaaac atttattttt
     4321 tgaggacttc ccaaaagtta tacactaaaa tataaattcc ttctttattc actgagatgg
     4381 cccaaagaga aatcagaatg tcaatcctag gggttagaat agcatcccat ctctatgcag
     4441 agtggattta ctagggcact ggcctcaaat tcctcctctt caacaggctt ctgataactc
     4501 cagtgcagca ccaactcaaa ctctacatgg tcccacttca ggaacaacac attgcatgta
     4561 attagcaagt ttaacttccc attggttttt gttgtcttta attacattac tgtattttag
     4621 catgattgaa tagtacaata atattggcca tcgttagaac acagtataac cttcctgaat
     4681 agtataccaa ttacttaatg tgaagtcata ctatttctta gaattggtgt gtttgacatt
     4741 taaaccacac ttctgtcctc cttgatcaca cactaactga tgcctttgag ggttactagt
     4801 gatttttttt ttgtctttaa gccaaggtga caactaaaat acctgtaatt ttaaatatta
     4861 aatacattca tgaaacaact caatttcagc tttcaaaaca attccatcca tatataaatt
     4921 tcactgaatt attattgatt tactgaagca atgctttatt tctgtctgca tagtcattgt
     4981 ttagctcatc tgatatgttg caggaggcag agccctagag ggacataggc ttgagtcatg
     5041 acagaaacct ttcatagaat gcactaagct gtggggtgaa tgctcagaga gacaaattct
     5101 ttctcaaata acaattcata tacttataaa ataatggcat ctgttgcctt gataaagaaa
     5161 aaaattttat tgaggtattt ttttaaatga gtgcagtgaa aatgtgaaag agatagtttc
     5221 tctgtacctc ttctgggcca taggagtggt atttattata gaacaattag caaaattgta
     5281 aaattaatac aataagccaa caaataccct tgttacagct gctcaggctc agctgtgcag
     5341 tagctggtgg attccccttg agtccctatt ccctgaactt ccatcctccc atctctgtgg
     5401 ccaaggaggc cttatcctcc atgtcagcac tgtctaagga agccctgtaa tgcagccatt
     5461 ctcccacagt gaagttagcc ttcgaaagtg ctcattctgt gaccttcaca caggaacaag
     5521 aacagtcatt tcatcttgat cagtggaatt gtctttattg caaagaagtg gctatttgag
     5581 actaacatgc ttcataattt cttcttcgtt gcatttacat ttttcttttt gtcttgtata
     5641 atttttaatg atttgttgta cagtgaaatc ctgtgaattg ttgaatctat ctcactttca
     5701 gtgacaaaat attgtatagg gtagaatttg aattaatctc ttcagataac ttttgatgca
     5761 caaatgtttc ggctaattat gttttgaccc agcagctctt tctgtttatc tgtacttgaa
     5821 acttcaattc atttcttaaa cgcacaacgc tccattctca gggaaccggt tacagcaaag
     5881 acatttcttg ctgtattttt ttttttcttg tcttgtgaca gatgtgcagt ctttatggga
     5941 ataagtagtg acaagcagac agacacagtt gttagaagaa tttcagaaac atacacacgc
     6001 atgaatgcat gcacattgcg gggcactgct atgaagttta tgcaagttca ggtcttccta
     6061 cataagtgcc acctgagact cattacatgt aatgcattta atgctcaggg acaaacaggg
     6121 aactggatga ttagatgtga ttccactgat atcaccacca agtcaccact tatgtttgag
     6181 atttgtgaag gcaataatat tgactagtcc actctatcag tattaataag catagaacat
     6241 atatataccc ccttttaatc tctcgttctc tctagaatta cctaagtgaa catgatgtga
     6301 tcctttagaa atgcccacat cttatgtatg tgtgtaaaga tacaaagaat tgatgtgaag
     6361 caacttttat tgttcacttc ctactttttg aaaatgttgg tttccatgag taccagaatc
     6421 acctgccaga cagtgcaagg tcacctgagt aagacagcgt ctcagcatcc aaagcatgca
     6481 gcagcaaatg gaaactgaag actaccacac cctgacctta atcctgtgtg aaattctgtc
     6541 tgaacattaa attctttatg atcaagacct ggatgagata catatatgtt tgttgccttt
     6601 cagattgtgt taatgtcctt tggtataagg ctttgaataa gttgttttta tggttacaat
     6661 gttctgctag cacatgccac ttttagatgc agataaaccc acttggacac taactcatgt
     6721 gtctcaagga agcaacttta tgaagagacg ttcattaact tgcatgtggc aaatgtggct
     6781 gttaggactg cactgctgat ttttttgaga ttttaagagg gacagggaag attttgcaaa
     6841 tttgatgagg tgacaggtgg atatttctag cttatgcatc ctctgggcaa tagtcatttg
     6901 caaaagtgag gatggaatac tctgaagtcc cagcaggctc ttcatgtggg aagtctgctg
     6961 gacttcacat ctgtgcagca tttggctgat tatattggga tgcgtaagtt tggttcatat
     7021 tgtaaaaatg agttcatctt agtttaaagt gggctactat gtttctgaaa gcaagatggt
     7081 gttccccttc ctttcactat attccgtgaa gccagctctg ctctgcctat tattgttaga
     7141 aacaagaaaa acacatgaac aatgtggctg ctacatgagc tcttccaggt agcctgtttc
     7201 ccctgagcaa ggggtttaat cattatggaa aataatgtct agatgccacg ttgatgacca
     7261 gcagggaaga tggctgcttg gaattgatat ggtgaggtca ctggtgaaca cttgattaag
     7321 tattggaaaa catgccaaga aagaactgtc ccctgaaaca aagagagtct ctaccagaaa
     7381 caatgatctg aggaaggcaa tgcttaagga cctgtcactg cttagccatt caatgaagac
     7441 cccttattga atgtattatc ccaccattta gctctatatg ctgaatgcca ttggagccaa
     7501 ggttgtaaga aagaatttaa gacatggaag tgctattagg ttttagctaa attcctaaca
     7561 ttccctgtca tgtttgcctc acaggatttg agctccatgt tatgacagaa catagtgctt
     7621 gtggggaccc agaacttctg ccttttaaag ctgacagatt ttccaaggaa gttaagtcaa
     7681 ctcccagaca caatcttgct ttcagtagat ggagggcaca aaaatcccag ggcagggcat
     7741 cacccagagg tagagcagtc gatcagaagc tcaagtactt tctactgttg ggtctactgg
     7801 gaatagcagc tgggcccagt cccagcaagc tggcctctca gacatcagca gagctccatt
     7861 aaagtctcat gacatgcaag tggatcctca gagcagatcc ccgtgaggca tagagggagg
     7921 cattgagctc catgtagagc tgctgctgct gtctttgatg ctagggattg agcccagagc
     7981 atagcacata gtaaacaagc actctgttgc taaacaagaa acaggcccca aagcagcagt
     8041 tttatctgcc tgtaagtcaa catggctgcc tccccggggc cttgttttct tccccatctt
     8101 cctacttagg ctcattttgt atgacaataa aattttttac aaaacaattt gtgaagaatt
     8161 tgaatgggta gatgcgagga tgtgtgaata tgattgctga gtgtgattgg gcaagggaca
     8221 ctgcagatat tttcatgatt tgcctgcatg gtgactagct gtggaaagat tccattgttt
     8281 tcttccttca aactgggaaa cagaaatcat ttgaagaaaa atcatttcag tgttttgctt
     8341 gctgacattt agcaggtacg atctgaattg aaaggctttc tgacttctgt ggtttccagt
     8401 ggtgattccg tgaagatcaa agagtggtgc tgtcctctga gaggaagcgg agcctctgtt
     8461 ttttctccag cagtgcagtt atttctagat gtgcctgaaa cagacaagaa tcctcccaat
     8521 gtgccttctc cttggttcct gagctaggat attgttttgt cctagcacct tccattcagg
     8581 tcgcccatgt tttgcagatc atcagtgccc tcatccctac cacagaaggg ggcctgcatt
     8641 ttagggggac acaaaggcag caagtgtatc tgttggctgc tccccaaagc tctctgtgaa
     8701 cacaatgagt ctctaacaca accacacagt catagcctga aaaagagaaa gagatgcctc
     8761 tatagaagat tcacccgaaa gatgaaagag tatgttattt tttctgctat tgtgtaaatg
     8821 agctttgtaa aatgctgaca aaaataaaaa tgtattttca aatta
//
