LOCUS       NM_010889              22489 bp    mRNA    linear   ROD 23-NOV-2023
DEFINITION  Mus musculus nebulin (Neb), mRNA.
ACCESSION   NM_010889 XM_130232 XM_976519
VERSION     NM_010889.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 22489)
  AUTHORS   Lindqvist J and Granzier H.
  TITLE     Pharmacological Inhibition of Myostatin in a Mouse Model of Typical
            Nemaline Myopathy Increases Muscle Size and Force
  JOURNAL   Int J Mol Sci 24 (20), 15124 (2023)
   PUBMED   37894805
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22489)
  AUTHORS   Slick RA, Tinklenberg JA, Sutton J, Zhang L, Meng H, Beatka MJ,
            Vanden Avond M, Prom MJ, Ott E, Montanaro F, Heisner J, Toro R,
            Granzier H, Geurts AM, Stowe DF, Hill RB and Lawlor MW.
  TITLE     Aberrations in Energetic Metabolism and Stress-Related Pathways
            Contribute to Pathophysiology in the Neb Conditional Knockout Mouse
            Model of Nemaline Myopathy
  JOURNAL   Am J Pathol 193 (10), 1528-1547 (2023)
   PUBMED   37422147
  REMARK    GeneRIF: Aberrations in Energetic Metabolism and Stress-Related
            Pathways Contribute to Pathophysiology in the Neb Conditional
            Knockout Mouse Model of Nemaline Myopathy.
REFERENCE   3  (bases 1 to 22489)
  AUTHORS   Ranu N, Laitila J, Dugdale HF, Mariano J, Kolb JS,
            Wallgren-Pettersson C, Witting N, Vissing J, Vilchez JJ, Fiorillo
            C, Zanoteli E, Auranen M, Jokela M, Tasca G, Claeys KG, Voermans
            NC, Palmio J, Huovinen S, Moggio M, Beck TN,
            Kontrogianni-Konstantopoulos A, Granzier H and Ochala J.
  TITLE     NEB mutations disrupt the super-relaxed state of myosin and remodel
            the muscle metabolic proteome in nemaline myopathy
  JOURNAL   Acta Neuropathol Commun 10 (1), 185 (2022)
   PUBMED   36528760
  REMARK    GeneRIF: NEB mutations disrupt the super-relaxed state of myosin
            and remodel the muscle metabolic proteome in nemaline myopathy.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 22489)
  AUTHORS   Wang Z, Grange M, Pospich S, Wagner T, Kho AL, Gautel M and Raunser
            S.
  TITLE     Structures from intact myofibrils reveal mechanism of thin filament
            regulation through nebulin
  JOURNAL   Science 375 (6582), eabn1934 (2022)
   PUBMED   35175800
  REMARK    GeneRIF: Structures from intact myofibrils reveal mechanism of thin
            filament regulation through nebulin.
REFERENCE   5  (bases 1 to 22489)
  AUTHORS   Zhang X, Wang Z, Xu Q, Chen Y, Liu W, Zhong T, Li H, Quan C, Zhang
            L and Cui CP.
  TITLE     Splicing factor Srsf5 deletion disrupts alternative splicing and
            causes noncompaction of ventricular myocardium
  JOURNAL   iScience 24 (10), 103097 (2021)
   PUBMED   34622152
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 22489)
  AUTHORS   Miner JH, Miller JB and Wold BJ.
  TITLE     Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic
            mouse heart
  JOURNAL   Development 114 (4), 853-860 (1992)
   PUBMED   1618148
REFERENCE   7  (bases 1 to 22489)
  AUTHORS   Askew DS, Bartholomew C, Buchberg AM, Valentine MB, Jenkins NA,
            Copeland NG and Ihle JN.
  TITLE     His-1 and His-2: identification and chromosomal mapping of two
            commonly rearranged sites of viral integration in a myeloid
            leukemia
  JOURNAL   Oncogene 6 (11), 2041-2047 (1991)
   PUBMED   1682866
REFERENCE   8  (bases 1 to 22489)
  AUTHORS   Siracusa LD, Alvord WG, Bickmore WA, Jenkins NA and Copeland NG.
  TITLE     Interspecific backcross mice show sex-specific differences in
            allelic inheritance
  JOURNAL   Genetics 128 (4), 813-821 (1991)
   PUBMED   1916246
REFERENCE   9  (bases 1 to 22489)
  AUTHORS   Malo D, Schurr E, Dorfman J, Canfield V, Levenson R and Gros P.
  TITLE     Three brain sodium channel alpha-subunit genes are clustered on the
            proximal segment of mouse chromosome 2
  JOURNAL   Genomics 10 (3), 666-672 (1991)
   PUBMED   1679748
REFERENCE   10 (bases 1 to 22489)
  AUTHORS   Schurr E, Skamene E and Gros P.
  TITLE     Mapping of the gene coding for the muscle protein nebulin (Neb) to
            the proximal region of mouse chromosome 2
  JOURNAL   Cytogenet Cell Genet 57 (4), 214-216 (1991)
   PUBMED   1683831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845355.11 and AL844571.8.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_976519.2, XM_130232.8.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849375
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-308               AL845355.11        80803-81110         c
            309-390             AL845355.11        77346-77427         c
            391-455             AL845355.11        76758-76822         c
            456-497             AL845355.11        73121-73162         c
            498-698             AL845355.11        71030-71230         c
            699-806             AL845355.11        69248-69355         c
            807-911             AL845355.11        68982-69086         c
            912-1016            AL845355.11        68009-68113         c
            1017-1121           AL845355.11        67275-67379         c
            1122-1226           AL845355.11        61946-62050         c
            1227-1331           AL845355.11        56088-56192         c
            1332-1439           AL845355.11        55430-55537         c
            1440-1556           AL845355.11        52841-52957         c
            1557-1661           AL845355.11        50998-51102         c
            1662-1769           AL845355.11        50797-50904         c
            1770-1874           AL845355.11        50588-50692         c
            1875-1973           AL845355.11        49998-50096         c
            1974-2078           AL845355.11        48841-48945         c
            2079-2186           AL845355.11        47596-47703         c
            2187-2300           AL845355.11        47406-47519         c
            2301-2402           AL845355.11        46342-46443         c
            2403-2510           AL845355.11        46139-46246         c
            2511-2615           AL845355.11        45943-46047         c
            2616-2714           AL845355.11        44754-44852         c
            2715-2819           AL845355.11        41789-41893         c
            2820-2927           AL845355.11        41121-41228         c
            2928-3041           AL845355.11        40931-41044         c
            3042-3239           AL845355.11        38551-38748         c
            3240-3347           AL845355.11        37603-37710         c
            3348-3446           AL845355.11        35940-36038         c
            3447-3551           AL845355.11        35113-35217         c
            3552-3659           AL845355.11        34925-35032         c
            3660-3971           AL845355.11        33354-33665         c
            3972-4178           AL845355.11        33066-33272         c
            4179-4283           AL845355.11        31938-32042         c
            4284-4391           AL845355.11        31083-31190         c
            4392-4703           AL845355.11        29356-29667         c
            4704-4910           AL845355.11        28267-28473         c
            4911-5015           AL845355.11        26562-26666         c
            5016-5123           AL845355.11        24902-25009         c
            5124-5435           AL845355.11        23776-24087         c
            5436-5642           AL845355.11        22748-22954         c
            5643-5747           AL845355.11        22156-22260         c
            5748-5855           AL845355.11        21944-22051         c
            5856-6167           AL845355.11        21086-21397         c
            6168-6374           AL845355.11        19670-19876         c
            6375-6479           AL845355.11        16197-16301         c
            6480-6587           AL845355.11        15172-15279         c
            6588-6899           AL845355.11        13611-13922         c
            6900-7106           AL845355.11        13283-13489         c
            7107-7211           AL845355.11        12520-12624         c
            7212-7319           AL845355.11        10006-10113         c
            7320-7631           AL845355.11        6198-6509           c
            7632-7835           AL845355.11        5808-6011           c
            7836-7940           AL845355.11        2806-2910           c
            7941-8048           AL844571.8         181804-181911       c
            8049-8360           AL844571.8         181178-181489       c
            8361-8564           AL844571.8         180673-180876       c
            8565-8669           AL844571.8         180341-180445       c
            8670-8777           AL844571.8         180147-180254       c
            8778-9089           AL844571.8         179166-179477       c
            9090-9293           AL844571.8         178675-178878       c
            9294-9398           AL844571.8         178117-178221       c
            9399-9506           AL844571.8         174292-174399       c
            9507-9818           AL844571.8         171788-172099       c
            9819-10022          AL844571.8         169741-169944       c
            10023-10127         AL844571.8         169345-169449       c
            10128-10235         AL844571.8         167866-167973       c
            10236-10547         AL844571.8         166427-166738       c
            10548-10751         AL844571.8         165778-165981       c
            10752-10856         AL844571.8         164581-164685       c
            10857-10964         AL844571.8         160777-160884       c
            10965-11276         AL844571.8         159437-159748       c
            11277-11480         AL844571.8         158065-158268       c
            11481-11585         AL844571.8         156852-156956       c
            11586-11693         AL844571.8         155506-155613       c
            11694-12005         AL844571.8         154552-154863       c
            12006-12209         AL844571.8         152541-152744       c
            12210-12314         AL844571.8         151333-151437       c
            12315-12422         AL844571.8         151083-151190       c
            12423-12734         AL844571.8         149829-150140       c
            12735-12938         AL844571.8         149028-149231       c
            12939-13043         AL844571.8         148154-148258       c
            13044-13151         AL844571.8         147099-147206       c
            13152-13463         AL844571.8         145322-145633       c
            13464-13667         AL844571.8         139467-139670       c
            13668-13772         AL844571.8         138837-138941       c
            13773-13877         AL844571.8         135492-135596       c
            13878-14189         AL844571.8         135075-135386       c
            14190-14294         AL844571.8         134067-134171       c
            14295-14393         AL844571.8         133416-133514       c
            14394-14495         AL844571.8         133135-133236       c
            14496-14603         AL844571.8         132913-133020       c
            14604-14915         AL844571.8         131926-132237       c
            14916-15020         AL844571.8         130861-130965       c
            15021-15125         AL844571.8         130644-130748       c
            15126-15230         AL844571.8         130246-130350       c
            15231-15338         AL844571.8         129467-129574       c
            15339-15452         AL844571.8         129250-129363       c
            15453-15650         AL844571.8         128651-128848       c
            15651-15755         AL844571.8         128207-128311       c
            15756-15860         AL844571.8         127412-127516       c
            15861-15965         AL844571.8         127209-127313       c
            15966-16073         AL844571.8         126811-126918       c
            16074-16187         AL844571.8         125094-125207       c
            16188-16385         AL844571.8         124399-124596       c
            16386-16490         AL844571.8         123983-124087       c
            16491-16595         AL844571.8         123211-123315       c
            16596-16703         AL844571.8         121989-122096       c
            16704-16808         AL844571.8         120382-120486       c
            16809-16916         AL844571.8         118877-118984       c
            16917-17021         AL844571.8         118205-118309       c
            17022-17126         AL844571.8         118005-118109       c
            17127-17225         AL844571.8         116965-117063       c
            17226-17336         AL844571.8         116461-116571       c
            17337-17441         AL844571.8         115755-115859       c
            17442-17546         AL844571.8         115055-115159       c
            17547-17651         AL844571.8         114511-114615       c
            17652-17756         AL844571.8         112439-112543       c
            17757-17861         AL844571.8         112184-112288       c
            17862-17966         AL844571.8         111268-111372       c
            17967-18071         AL844571.8         109996-110100       c
            18072-18176         AL844571.8         108597-108701       c
            18177-18281         AL844571.8         106317-106421       c
            18282-18389         AL844571.8         105858-105965       c
            18390-18494         AL844571.8         102047-102151       c
            18495-18599         AL844571.8         100554-100658       c
            18600-18704         AL844571.8         100107-100211       c
            18705-18809         AL844571.8         99372-99476         c
            18810-18920         AL844571.8         99171-99281         c
            18921-19031         AL844571.8         98192-98302         c
            19032-19133         AL844571.8         97874-97975         c
            19134-19238         AL844571.8         97664-97768         c
            19239-19349         AL844571.8         93024-93134         c
            19350-19454         AL844571.8         92428-92532         c
            19455-19559         AL844571.8         91644-91748         c
            19560-19664         AL844571.8         90145-90249         c
            19665-19775         AL844571.8         87752-87862         c
            19776-19886         AL844571.8         87177-87287         c
            19887-20000         AL844571.8         86522-86635         c
            20001-20105         AL844571.8         85490-85594         c
            20106-20210         AL844571.8         84653-84757         c
            20211-20315         AL844571.8         83956-84060         c
            20316-20408         AL844571.8         83241-83333         c
            20409-20501         AL844571.8         82062-82154         c
            20502-20594         AL844571.8         80417-80509         c
            20595-20687         AL844571.8         79876-79968         c
            20688-20780         AL844571.8         75641-75733         c
            20781-20873         AL844571.8         73949-74041         c
            20874-20966         AL844571.8         73552-73644         c
            20967-21059         AL844571.8         73122-73214         c
            21060-21167         AL844571.8         72175-72282         c
            21168-21351         AL844571.8         71679-71862         c
            21352-21444         AL844571.8         71346-71438         c
            21445-21597         AL844571.8         70222-70374         c
            21598-21704         AL844571.8         69725-69831         c
            21705-22489         AL844571.8         59232-60016         c
FEATURES             Location/Qualifiers
     source          1..22489
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 29.98 cM"
     gene            1..22489
                     /gene="Neb"
                     /note="nebulin"
                     /db_xref="GeneID:17996"
                     /db_xref="MGI:MGI:97292"
     exon            1..308
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            309..390
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            391..455
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     CDS             420..21878
                     /gene="Neb"
                     /codon_start=1
                     /product="nebulin"
                     /protein_id="NP_035019.1"
                     /db_xref="CCDS:CCDS50584.1"
                     /db_xref="GeneID:17996"
                     /db_xref="MGI:MGI:97292"
                     /translation="MADEEEYEEVIEYYTEETVYEEVPGETITEVYETTTTRTSDYGQ
                     SETATPALAQPQPAKPVERKKVIRKKVDSSKFMTPYIQHSQKMQDLFSSNKYKENYEK
                     AKGQPYAITSDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQ
                     QVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKALFYPYND
                     SPELRRVAQAQKALSDIAYKKGLTEQQTQFTSLPDPPEVEFAKKVTNQVSKQKYKEDY
                     EKKVKGKWSETPCFEIATARMNADNLSSRKYQEDFENMKDQIYFMQTETPEYKMNKQA
                     GVAASKVKYKQDYEKNKGKADYNVLPASENPLLRQLKTAGNVLSDKLYKENYEKTKAR
                     SINYCETPKFQLDTVLQNFSSDTKYKDSYLKNILGHYVGSFEDPYHTHCMKVTAQNSD
                     KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHAYKVHPDKTKFTQVTDSPVLVQ
                     AQVNSKQLSDLNYKAKHESEKFKCHIPPDAPAFIQHRVNAYNLSDNVYKQDWEKSKAK
                     KFDIKVDAIPLLAAKANSKNASDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN
                     QSDRLYRENYEKTKAKSMNYCETPKYQLDTLLKNFSEAKYKDSYVKNMLGHYVGSFED
                     PYHTHCMKVSAQNSDKSYKAEYEEDKGKCYFPQTITQEYESIKKLDQCKDHTYKVHPD
                     KTRFTAVTDTPVLLQAQLNTKQLSDLNYKAKHEGEKFKCSVPADAPEFIQHRVNAYNL
                     SDNVYKHDWEKSKAKKFDIKVDAIPLLAAKANSKNASDVMYKKDYEKSKGKMIGALSI
                     NDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMIQVTQAKKSQAIASDVDYKH
                     VLHNYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASE
                     ILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEILHKYNLPADLP
                     QFIQAKVNAYNISENMYKADLKDLSKKGYDLRIDAIPIKAAKAARQAASDIHYKKDYE
                     KAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKTKYNTPHDMFDVVAAKK
                     AQDVISNTNYKHSLHHYTYLPDAMDLELSKNMMHIQSDNAYKEDYNTWMKGIGWIPIG
                     SLDQEKVKKAGDALSEKKYRQHPDTLKFTSIVDSPVMVQAKQNTQQASDILYKAKGED
                     VKHKYTLNPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLADAIPITAAKSSRN
                     IASDYKYKEAYEKAKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHT
                     PGDMVSITAARMAQDVATNVNYKQPLHHYTYLPDALSLEHTRNANQIQSDNVYKDEYN
                     SFFKGIGWIPIGSLEVEKAKKAGEALNERKYRQHPDTIKFTSVPDSMGMVLAQQNTKQ
                     LSDLNYKVEGEKMKHKYTMDPELPQFIQAKVNAINMSDAHYKADWKKTLAKGYDLRPD
                     AIPIVAAKSSRNIASDCKYKEAYEKARGKQIGFLSLQDDPKLVHYMNVAKIQSDREYK
                     KGYEASKTRYHTPLDMFSVTAAKKSQEVATNSNYRQPYHNYTLLPDALNVEHSRNAMQ
                     IQSDNLYKSDFTHWMKGIGWVPIDSLEVEKAKKAGEILSERKYRQHPEKLKFTYSMDT
                     MEQALNKSNKLTMDKRLYTEKWNKDKTSIHVMPDTPDILLSRVNQITMSDKLYKAGWE
                     EEKTKGYDLKPDAIAIKAAKASRDIASDYKYKQAYEQSKGKHIGFRSLEDDPKLVHFM
                     QVAKIQSDREYKKGYEKSKTSFHTPVDMFSVVAAKKSQEVATNANYRNIIHTYNMLPD
                     AMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQH
                     PDTLKYSTLMDSMNMVLAQNNAKIMNKNLYKQAWEADKTKIHIMPDIPEIVLAKANAI
                     NMSDKLYKLSLEESRKKGYDLRTDAIPIKAAKASRDIASDYKYKHSYEKEKGKMVGFR
                     SLEDDPKLVHSMQVAKMQSDREYKKNYEKTKTSYHTPADMLSVTAAKDAQANITNTNY
                     KRLIHKYILLPDAMNIELTRNMNHIQSDNEYKQDYREWYRGLGWSPAGSLEVEKAKKA
                     TEYASDQKYRQHPSTFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPD
                     TPDILQAKQNQTLYSQKSYRLGWEEALKKGYDLPVDAISVQLAKTSRDIASDFKYKQG
                     YRKQLGHHIGFLSVQDDPKLVLSMNVAKMQSDREYKKDFEKWKTKYTSPVDMLGVVLA
                     KKCQALVSDADYRNYLHQWTCLPDQNDVIQAKKVYELQSENMYKSDLEWLRGIGWSPL
                     GSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWD
                     KDKTQIHIMPDTPDIILAKANLINTSDKLYKMGYEELKKKGYDLPVDAIPIKAAKASR
                     EIASEYKYKEGFRKQLGHHIGARNIKDDPKMMWSMHVAKIQSDREYKKDFEKWKTKYS
                     SPVDMLGVVLAKKCQTLVSDADYRNYLHQWTCLPDQNDVIHARQAYDLQSDNVYKADL
                     QWLKGIGWIPSGSLEDEKNKRATQILSDHVYRQHPNKFKFSSLMDSMPMVLAKNNAIT
                     MNHHLYTEAWNKDKTTVHIMPDTPEVILAKQNKVNYSEKLYKLGLEEAKRKGYDMRLD
                     AIPIKTAKASRDIASDFKYKEGYRKQLGHHIGARGIHDDPKMMWSMHVAKIQSDREYK
                     KDFEKWKTKYSSPVDMLGVVLAKKCQTLVSDADYRNYLHQWTCLPDQNDVIHARQAYD
                     LQSDNMYKSDLQWMRGIGWVPIGSLDVEKCKRATEILSDKIYRQPPDKFKFTSVTDSL
                     EQVLAKNNAITMNKRLYTEAWDKDKTQIHIMPDTPEIMLARMNKVNYSESLYKLANEE
                     AKKKGYDLRSDAIPIVAAKASRDIASDYKYKDGYRKQLGHHIGARNIKDDPKMMWSMH
                     VAKIQSDREYKKDFEKWKTKYSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQ
                     NDVIHARQAYDLQSDNVYKSDLQWMRGIGWVPIGSLDVVKCKRAAEILSDNIYRQPPN
                     KFKFTSVTDSLEQVLAKSNALNMNKRLYTEAWDKDKIQIHVMPDTPEIMLARQNRINY
                     SESLYKLANEEAKKKGYDLRVDAIPIVAAKASRDIASDYKYKVGYRKQLGHHIGARNI
                     EDDPKMMWSMHVAKIQSDREYKKDFEKWKTKYSSPVDMLGVVLAKKCQTLVSDVDYRN
                     YLHQWTCLPDQNDVIHARQAYDLQSDNVYKSDLQWMRGIGWVPIGSLDVVKCKRAAEI
                     LSDNIYRQPPNKFKFTSVTDSLEQVLAKSNALNMNKRLYTEAWDKDKTQIHIMPDTPE
                     IMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRK
                     QLGHHIGARAIHDDPKMMWSLHIAKVQSDREYKKEFEKYKTRYSSPVDMLGIVLAKKC
                     QTLVSDVDYKHPLHEWTCLPDQNDVIQARKAYDLQSDNLYKADLEWMKGIGWVPIGSL
                     EVVKAKRATEILSDNIYRQRPDTLKFTSITDSLEQVLAKNNAITMNKRLYTEAWDNDK
                     KTIHVMPDTPEIMLAKLNRINYSDKLYKVSLEEARRQGYDLRVDAIPIRSAKASREIA
                     SDYKYKEGYRKQLGHHIGARNIKDDPKMMWSMHVAKIQSDREYKKDFEKWKTKYSSPV
                     DMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAVYKADLEWL
                     RGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKSNAITMSK
                     HLYTEAWDADKASIHVMPDTPEILLAKSNSANISHKLYTKGWDESKMKDYDLREDAIS
                     IKSAKASRDIASDYKYKEAYEKQKGHHIGAQSVEDDPRILCAMHAGKIYSDREYKKEF
                     QKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYRNYLHNWTCLPDQNDIIQAKKAYELQS
                     DSVYKADLEWLRGIGWMPEGSIEMTRVKGAQDLVNERLYRTRPEALKFTSIVDTPEVV
                     LAKANSLQMSERLYQEAWNKDKTNISLPLDTPAMLQAQINALQISNKLYQKDWDEAKQ
                     KGYDLRADAIEIKHAKASREIASEYKYKEGYRKQLGHHVGFRSLQDDPKLVWSIHAAK
                     IQSDREYKKAYEKSKGIYNTPLDMMSIVQAKKCQVLVSDVDYRNYLHQWTCLPDQNDV
                     IQAKKAYELQSDAIYKADLEWLRGIGWMPEGSPEVLRVKNAQEILCDSVYRTPVVKLK
                     YTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNK
                     LYREGWDEVKMSCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDN
                     KIRWALIAGKIQNEREYRLQWAKWKTKFQSPVDMLSILHSKKCQTLVSDIDYRNYLHE
                     WTCMPDQNDVIQAKKAYELQSDAVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEK
                     KYRTKIETLNFTPVDDRVDYVTAKQSSEIRDDIKYRKDWNAIKSKYTLTETPLLHTAQ
                     EAARILDQYLYKEGWEKQKATGYILPPDAVPFVHAHHSSDVQSELKYKAEHVKQRGHY
                     VGVPTMRDDPKLVWFEHAGQIQNDRLYKESYHKSKAKINIPADMVSVVAAKEGQNLVS
                     DIDYRQYLHQWTCHPDQNDVIQAKIAYDLQSDNVYKADLEWLRGIGWIPLDSVDHVRV
                     TKNQEMVNQIKYKKDALANYPNFTSVEDPPEIVLAKINSVNQSDVKYKETFNKAKGKY
                     IFSPDTPYISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSEL
                     KYKETYEKQKGHYLAGKEISEFPGVVHCLDFQQMRSALNYRRDYEDTKANVHIPNDMM
                     NHVLAKRCQYILSDLEYRHYFHQWTSLPEEPNVIRARNAQEILSDNVYKDDLNWLKGI
                     GCYVWDTPQILHAKKSYDLQSQLQYTAASKENLQNYNLVTDTPVYVTALQSGINASEV
                     KYKENYHQIKDKYTTVLETADYDRTKHLKSLYSSNIYKEAWDKVKATSYNLPTSTLSL
                     THAKNQKHLASHIKYREEYEKFKALYTLPKSVDDDPNTARCLRVGKLNIDRLYRSVYE
                     KNKMKINIVPDMVEMVTAKDSQKKVSEIDYRLHLHEWICHPDLQVNSHVRKVTDQISD
                     IVYKDDLTWLKGIGCYVWDTPEILHAKHAYDLRNDIKYKAHVQKTRNDYKLVTDTPVY
                     VQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSENLYKKGLRFL
                     PTGYRLPVDTPHFNHTKDTRYMSSYFKYKEAYEHIKANGYTLGPKDVPFVHVRRVNNV
                     TSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYT
                     PQVLHCRYVGDITSDIKYKEDLQILKGLGCFLYDTPDMVRSRHLRKLWSNYLYTDNAR
                     KMRDKYKVVLDTPEYRKVQELKTHLSELVYRASGKKQKSIFTSVPDTPDLLRAKRGQK
                     LQSQYLYVELATKERPHHHAGNQTTALQHAKDVKDMVSEKKYKIQYEKMKDKYTPVAD
                     TPILIRAKRAYWNASDLRYKETFQKTKGRYHTVKDALDIVYHRKVTDDISKVKYKENY
                     MSQLGIWSSIPDRPEHFHHRAVTDAVSDVKYKEDLTWLKGIGCYAYDTPDLTLAEQNK
                     TLYSKYKYKEVFERTKSNFKYVADCPINRHFKYATQLMNEKKYRADYEQRKDKYHLVV
                     DEPRHLLAKTAGDQISQIKYRKKYEKSKDKFTSVVDTPEHLRTTKVNKQISDILYKLE
                     YNKARPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIKPDAVHIKAAKD
                     AYKVNTNLDYKKQYEANKAYWKWTPDRPDFIQAAKSSLQQSDFEYKLDREFLKGCKLS
                     VTDDKDMVLALRNSLIESDLKYKEKHVKERGSCHAVPDTPQILLAKTVSNLVSENKYK
                     DHVKKHLAQGSYTTLPETRDTVHVKAVTKHVSDTNYKKKFVKEKGKSNYSIMQEPPEV
                     KHAMEVAKKQSDVAYKKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGS
                     HGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKTMKDANNLA
                     SEVKYKADLKKLHKPVTDMKESLIMHHVLNTSQLASSYQYKKNYEKSKGHYHTIPDNL
                     EQLHHREATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEE
                     SIKGRNLTGLEVTPALLHVRHATKIASEKEYRKDLEESIRGRGLTEMEDTPDMLRAKN
                     ATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKAN
                     FTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEMQRVRENQKNFSLL
                     QYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMLRVKQ
                     TQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENPGTGIPTTVTPEIE
                     RVKRNQENFSSVLYKESLGKGTPTAITPEMERVKRNQENFSSVLYKENMGKGTPLPVT
                     PEMERVKHNQENISSVLYKENVGKATPTPVTPEMQRVKRNQENISSVLYKENMGKATP
                     TPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPDMERAKRNQENISSVLYSDSFR
                     KQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNT
                     QDFSDINYRGIQRKVVEMEQKRNDQDQDTITGLRVWRTNPGSVFDYDPAEDNIQSRSL
                     HMINVQAQRRSRDQSRSASALSISGGEEKSEHSEAADQRLSTYSDGGAFFSATSTAYK
                     HVKTTQLPQQRSSSVATQQTTLSSIPSHPSTAGKIFRAIYDYIAADADEVSFKDGDAI
                     VNAQAIDEGWMYGTVQRTGRTGMLPANYVEAI"
     exon            456..497
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            498..698
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            699..806
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            807..911
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1016
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1121
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1226
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1331
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1439
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1556
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1661
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1769
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1874
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..1973
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2078
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2079..2186
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2300
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2402
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2403..2510
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2615
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2714
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2715..2819
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2927
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2928..3041
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3042..3239
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3240..3347
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3446
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3447..3551
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3552..3659
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3660..3971
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3972..4178
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4179..4283
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4284..4391
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4392..4703
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4704..4910
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4911..5015
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5016..5123
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5124..5435
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5436..5642
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5643..5747
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5748..5855
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5856..6167
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6168..6374
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6375..6479
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6480..6587
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6588..6899
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6900..7106
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7107..7211
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7212..7319
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7320..7631
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7632..7835
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7836..7940
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7941..8048
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8049..8360
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8361..8564
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8565..8669
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8670..8777
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8778..9089
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9090..9293
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9294..9398
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9399..9506
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9507..9818
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9819..10022
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10023..10127
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10128..10235
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10236..10547
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10548..10751
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10752..10856
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10857..10964
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10965..11276
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11277..11480
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11481..11585
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11586..11693
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11694..12005
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12006..12209
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12210..12314
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12315..12422
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12423..12734
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12735..12938
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12939..13043
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13044..13151
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13152..13463
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13464..13667
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13668..13772
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13773..13877
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13878..14189
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14190..14294
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14295..14393
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14394..14495
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14496..14603
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14604..14915
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14916..15020
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15021..15125
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15126..15230
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15231..15338
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15339..15452
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15453..15650
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15651..15755
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15756..15860
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15861..15965
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15966..16073
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16074..16187
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16188..16385
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16386..16490
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16491..16595
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16596..16703
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16704..16808
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16809..16916
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16917..17021
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17022..17126
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17127..17225
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17226..17336
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17337..17441
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17442..17546
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17547..17651
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17652..17756
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17757..17861
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17862..17966
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17967..18071
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18072..18176
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18177..18281
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18282..18389
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18390..18494
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18495..18599
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18600..18704
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18705..18809
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18810..18920
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18921..19031
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19032..19133
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19134..19238
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19239..19349
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19350..19454
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19455..19559
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19560..19664
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19665..19775
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19776..19886
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19887..20000
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20001..20105
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20106..20210
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20211..20315
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20316..20408
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20409..20501
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20502..20594
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20595..20687
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20688..20780
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20781..20873
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20874..20966
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20967..21059
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21060..21167
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21168..21351
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21352..21444
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21445..21597
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21598..21704
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21705..22489
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagtcagg tgcaagtctt agctgcagtc ccggacgcca tcttggaact gctgccacac
       61 ccgctcctca catctccctc ttttttcttt ttctgccttt tttcttttct gacctccctg
      121 ggtgcccggg gtccccgtag cagcattgag gcgttcctgc aataaaggct gttgagaaga
      181 atccgaccat gttgtgtctt ccttgccggc caaggtggcc gcaacatact gatccaacag
      241 ggagcagaca aatttagctg ggaatttggg actttcattt aggaaggaat gaactcaaga
      301 agtctaaggt ttgaacaaga gctacagaaa gggaaggata tccgtggaag ccaatggttt
      361 tccggaagaa aataaccccg ttgccttgag tttgtaggtg ccactactac tctggaaaaa
      421 tggcggatga ggaagagtat gaggaggtga tagagtacta cacagaggag acagtttacg
      481 aagaggtgcc aggagagaca attacagaag tctatgagac cacaacgaca aggacatcgg
      541 actatggcca atcagaaact gccacaccag cgctggcaca gccacaacca gcaaagccgg
      601 tggagcggaa gaaggtcatc cgaaagaagg tggactcgtc caagttcatg accccctaca
      661 ttcaacacag tcagaaaatg caggatcttt tcagctcaaa taaatacaaa gagaactatg
      721 agaaagcaaa gggacagcca tacgccatca caagtgatac tccagaactt cgcagaatca
      781 agaaagtcca ggatcaactc agtgaggtta agtatcgaat ggatggagat gttgctaaaa
      841 ctatctgtca tgtggatgaa aaagcaaaag acattgaaca tgctaagaaa gtgtcgcagc
      901 aagtcagcaa ggttttatac aagcagaact gggaagacac caaggataag tacctgcttc
      961 cccctgatgc ccctgaactt gtccaagccg tcaagaacac agccatgttc agtaagaaac
     1021 tgtacactga agactgggaa gcagacaagg cattgtttta tccctataat gacagtccgg
     1081 agctgagaag ggtagcccag gcccagaaag cactgagtga tattgcctac aaaaaaggac
     1141 tcactgagca gcaaactcag ttcacgtccc tgcctgatcc tcctgaggtc gaatttgcca
     1201 agaaagtaac caaccaagtg agcaagcaaa aatataaaga agactatgag aagaaagtca
     1261 aaggaaaatg gagtgagaca ccatgctttg aaattgcaac agccagaatg aatgctgaca
     1321 atctcagctc aaggaagtat caggaagact ttgagaacat gaaagaccag atctacttca
     1381 tgcagaccga aacacctgag tataaaatga ataaacaggc tggagtcgct gctagcaagg
     1441 taaaatacaa acaagactat gaaaagaata aaggaaaagc agactataat gtactccctg
     1501 cttcagagaa cccactgctc aggcagctga agacagctgg aaacgtcctc agtgataaac
     1561 tatacaagga aaactatgaa aagaccaaag caaggagcat caattactgt gagaccccca
     1621 agtttcagct tgacacagtg ctacagaact tcagtagtga cactaaatat aaagattcct
     1681 acctaaagaa tatcttggga cactacgtgg gcagctttga ggacccgtat cacacacact
     1741 gtatgaaagt tacagcccaa aatagtgata aaaactacaa agctgagtat gaagaggaca
     1801 gaggcaaagg cttcttcccc cagaccatta cccaggaata tgaagcaatc aagaaactgg
     1861 accagtgtaa agatcacgcc tacaaagtcc acccagataa gacaaagttc actcaagtca
     1921 cagactctcc tgtcctggtg caagcccagg tcaattccaa acagctgagt gatctaaatt
     1981 acaaagccaa acatgaaagt gaaaaattca agtgtcatat acctccggat gctcctgcct
     2041 ttatccagca cagagtgaac gcctataacc taagtgacaa tgtctacaaa caagactggg
     2101 agaagagcaa agctaagaag tttgacatca aggtggatgc catcccactg ctggcagcca
     2161 aagccaacag caagaatgcc agtgatgtga tgtacaagaa ggactatgag aagagcaaag
     2221 gcaagatgat cggtgccctc agcatcaatg atgaccccaa gatgctgcac tccctgaaga
     2281 ccgccaagaa ccagagtgat agactctaca gagaaaacta tgagaagaca aaggccaaga
     2341 gtatgaatta ctgtgagacc cccaagtatc aacttgacac ccttctgaag aacttcagtg
     2401 aggctaaata taaagattcc tatgtaaaga atatgttggg ccactacgta ggcagctttg
     2461 aagacccata ccatacacac tgcatgaagg tttctgctca aaacagtgat aagagttaca
     2521 aagcagaata tgaagaagat aaagggaaat gctatttccc tcagacaata acccaagaat
     2581 atgaatctat caagaagttg gaccagtgta aagatcacac ctacaaagtg catcctgata
     2641 agaccaggtt cacagcagtc accgacactc ccgtgctgtt gcaagcccag ctcaacacca
     2701 aacagctcag tgatctgaat tacaaagcaa agcatgaagg tgagaaattc aagtgcagcg
     2761 tgccagcaga tgcaccggaa ttcatccagc acagagtcaa tgcttataac ctgagtgata
     2821 atgtctacaa gcatgactgg gagaagagca aagctaagaa gttcgacatc aaggtggatg
     2881 ccatcccact gctggcagcc aaagccaaca gcaagaatgc cagtgatgtg atgtacaaga
     2941 aggactatga gaagagcaaa ggcaagatga tcggtgccct cagcatcaat gatgacccca
     3001 agatgctgca ctcgctgaag accgccaaga accagagcga ccgtgaatat cggaaggact
     3061 atgaaaagtc aaaaacgatc tacacagccc ctcttgacat gatccaagtc acccaagcta
     3121 agaaatctca ggcgattgcc agcgacgtgg actataaaca tgtcttgcac aactatagct
     3181 accctcctga cagcatcaat gtggacctgg ccaagaaggc ctacgcattg cagagtgatg
     3241 tggagtacaa agctgactac aacagttgga tgaagggctg tggctgggtg ccctttggtt
     3301 ccctggagat ggaaaaggca aagcgcgcct cggaaattct taacgagaaa aaataccgcc
     3361 aacatccaga tacgctcaag tttacctcaa ttgaagatgc tcccattaca gtgcagtcta
     3421 aaattaacca ggcccagagg agcgatattg cttacaaagc caagggggag gaaattctgc
     3481 ataagtacaa cctgccagca gacctgccgc agttcattca ggctaaggtg aacgcctaca
     3541 acatcagcga gaatatgtac aaggctgact tgaaagactt aagcaagaag ggctatgacc
     3601 tgagaattga tgccatcccc atcaaagccg ccaaagctgc ccgacaggct gcaagtgata
     3661 ttcactataa gaaagattat gaaaaggcca aagggaaaat ggtcggattc caaagtctcc
     3721 aagacgatcc taaactggtt cattacatga atgtggccaa gatacagtca gacagggagt
     3781 ataagaaaga ctacgaaaag acgaagacca aatacaatac acctcacgac atgttcgacg
     3841 ttgtggcggc taagaaggca caggatgtga tcagcaatac caactacaag cactctctcc
     3901 accactacac ctacctgccg gacgctatgg acctggagct atccaagaac atgatgcaca
     3961 tacagagcga taatgcctac aaggaagatt ataatacctg gatgaagggc attggctgga
     4021 ttccgattgg tagccttgac caagagaaag ttaaaaaggc aggggatgcc ctgagtgaaa
     4081 agaaatacag gcaacatccg gacacactca agttcaccag catcgtggac tccccggtga
     4141 tggtgcaggc aaagcagaac acgcagcaag ccagtgatat cttatacaaa gctaaaggag
     4201 aagacgtgaa gcataagtat actctgaatc ctgatctccc acagtttctc caggccaagt
     4261 gcaatgctta caacataagt gacgtctgct acaagcggga ctggcatgac ttaatagcca
     4321 aaggcaacaa tgtcctggct gatgctattc cgatcaccgc ggccaagtca tcaagaaaca
     4381 ttgccagtga ttataaatac aaagaggctt atgagaaggc aaagggaaag cacgttggct
     4441 tcagaagcct ccaggacgac cccaagttgg tccattatat gaatgtggcg aagttgcagt
     4501 cagaccgaga atacaagaaa aactatgaga acaccaagac aagttaccac acccctggag
     4561 acatggtcag catcactgct gcaaggatgg cccaggacgt ggctaccaac gtcaactaca
     4621 aacaaccctt acatcactat acatacctgc ctgatgcctt gagtcttgag cacacaagga
     4681 atgccaatca aattcagagt gacaatgtgt acaaagacga gtacaacagc ttcttcaagg
     4741 gcattgggtg gatccccatc ggctcgctgg aagtggagaa ggccaagaaa gcaggcgagg
     4801 cactgaatga gaggaagtac cgacaacacc cagacaccat caagttcaca agtgtgccag
     4861 actccatggg catggttttg gctcagcaga acacaaagca gctaagtgat ttgaactaca
     4921 aagtagaggg agagaaaatg aagcataaat atacaatgga ccctgaatta ccacagttca
     4981 ttcaagccaa agttaatgcc atcaacatga gtgatgctca ttacaaagca gactggaaga
     5041 aaacgctggc caagggttac gacttgagac cagatgccat tcccatcgtt gctgccaaaa
     5101 gttcaaggaa catcgctagt gactgcaaat acaaggaggc ctatgagaaa gccagaggca
     5161 agcaaattgg ctttctcagt cttcaggatg accctaagct ggttcactac atgaatgtgg
     5221 ccaaaataca atcagaccgt gaatataaga agggatatga ggccagcaag acccggtacc
     5281 acacacccct ggatatgttc agtgtgactg ctgcaaagaa atctcaggaa gttgcgacca
     5341 acagcaacta caggcagccc taccacaact acaccctctt gcctgatgcc ttgaatgtgg
     5401 aacactccag gaatgccatg caaatccaga gtgataatct atacaaatcc gacttcaccc
     5461 actggatgaa aggtatcggc tgggtcccca tagactcctt ggaggtagag aaggcaaaga
     5521 aagctgggga gattctgagt gagagaaagt atcgccagca ccccgagaag ctgaagttca
     5581 catattccat ggacaccatg gaacaggcac ttaacaaaag caacaagctg actatggata
     5641 agaggctgta cactgagaag tggaacaaag acaagaccag cattcatgtc atgcctgaca
     5701 ctccagacat cttgctctcc agagtaaacc agatcacaat gagtgataaa ctctacaagg
     5761 ctggctggga agaagagaag acgaaaggct atgatctcaa gcctgatgcc atcgcaataa
     5821 aggctgcaaa ggcctccaga gatattgcca gtgattacaa gtacaagcaa gcctatgaac
     5881 aatccaaagg gaagcacatt ggcttccgca gcctggaaga cgaccccaag ctggtgcact
     5941 tcatgcaggt ggccaagatt cagtcagacc gggaatacaa gaagggctat gagaaatcca
     6001 agacatcttt ccacaccccg gtggacatgt tcagtgtggt ggcagccaag aagtcccagg
     6061 aagtggccac caacgccaac tacaggaaca tcatccacac ctacaacatg cttcctgatg
     6121 ccatgagctt tgagttggcc aagaacatga tgcagattca aagtgataat cagtataagg
     6181 cagactatgc cgacttcatg aagggcattg gatggctccc cctcggctcc ctggaagctg
     6241 agaaaaacaa gaaagccatg gagattatca gtgagaagaa gtaccggcaa cacccagata
     6301 ctttgaagta ctccacacta atggactcaa tgaacatggt cttggctcag aataatgcaa
     6361 aaattatgaa taaaaatctc tataaacaag catgggaggc tgacaagaca aaaatccaca
     6421 tcatgcctga tatccccgag atcgttttgg ccaaagcaaa tgcaatcaac atgagcgata
     6481 aactctataa gctctctctg gaagaatcta gaaagaaagg ctatgacctc agaacggatg
     6541 caattcctat caaagctgcc aaagcatcaa gagatattgc aagtgattat aaatacaagc
     6601 acagttatga aaaggagaaa ggaaaaatgg ttggttttcg cagtctggag gatgatccca
     6661 aattagtcca ttccatgcaa gtggctaaga tgcagtctga tcgagagtac aagaaaaact
     6721 atgagaagac gaagaccagc taccatactc ctgccgacat gctgagcgtc acagcagcca
     6781 aggatgcgca agccaacatc accaacacca actacaagcg cctcattcac aagtacatcc
     6841 tcctcccaga cgcaatgaac atcgagctga ccaggaacat gaatcacatt cagagtgaca
     6901 atgaatataa gcaagactac agggagtggt accgagggct tggctggagc ccagctggct
     6961 ccctagaggt ggagaaggcc aagaaagcaa cggaatatgc cagcgatcag aagtaccggc
     7021 agcatcccag caccttccag tttaaaaagt tgactgactc catggacatg gtactggcga
     7081 agcagaatgc tcacaccatg aataagcatt tatacactat tgactggaat aaagacaaaa
     7141 ccaagattca tgtgatgccg gatacaccag atattttgca agccaagcag aatcaaacac
     7201 tttacagtca gaaatcctat agacttggtt gggaagaggc tctgaagaaa ggctatgatc
     7261 tccctgttga tgcgatttct gtccagctgg ccaagacatc aagggacatt gctagtgact
     7321 ttaaatataa acaaggctac cggaaacaac tgggacacca tattggattc ctcagtgtgc
     7381 aagatgaccc aaagcttgtg ctatcaatga atgtagccaa aatgcagagc gacagggagt
     7441 acaagaagga ctttgagaag tggaaaacca aatacaccag ccctgtggac atgctggggg
     7501 tggtgttggc caagaagtgc caggccttgg tcagtgatgc tgactacagg aactacctac
     7561 accagtggac gtgcctacct gaccagaatg acgtcatcca agctaaaaag gtctatgagc
     7621 tacaaagtga gaatatgtat aagtctgacc tagagtggct gagaggcata ggatggagtc
     7681 ccctgggttc tttggaagca gaaaagaaca agcgggcttc agaaatcatc agtgagaaga
     7741 aataccgcca acctccagac agaaataagt tcaccagcat ccctgacgcc atggacatag
     7801 ttctggctaa aacaaatgcc aaaaacagga gtgacagact ttatagagaa gcttgggaca
     7861 aggacaagac tcagatccac atcatgcctg acactcctga catcattctg gctaaagcaa
     7921 acttaatcaa tacaagtgat aaactctaca aaatgggtta tgaagaactg aagaagaaag
     7981 gatatgatct tcctgtggac gccattccaa tcaaagcagc aaaagcatcc cgggagattg
     8041 ccagtgaata caaatacaaa gaaggcttcc gaaagcaact cggccaccac attggggctc
     8101 ggaacatcaa ggatgacccc aagatgatgt ggtccatgca cgtggccaag atccagagtg
     8161 acagggagta caagaaggac tttgagaagt ggaagaccaa gtatagcagc ccagtggaca
     8221 tgctgggggt ggtgctggcc aagaagtgcc agaccttggt cagcgatgct gactacagga
     8281 actacctaca ccaatggaca tgcctgcctg atcagaatga tgtcatccac gctcggcagg
     8341 cctatgatct ccagagcgat aatgtgtaca aggctgatct tcagtggctg aaaggcattg
     8401 gctggatacc ttctggttcc ctcgaggatg agaaaaacaa acgagccact cagatcctga
     8461 gtgaccatgt ttaccgtcag cacccaaata aattcaagtt ttccagcctt atggactcca
     8521 tgccaatggt cttggcaaaa aataatgcta taaccatgaa ccatcacctc tatacagaag
     8581 cttggaataa ggataaaacc actgtccaca ttatgccaga tacccctgaa gttatactgg
     8641 ctaaacaaaa caaagtaaat tacagtgaga aattatataa gcttggcctg gaagaagcca
     8701 agaggaaagg ctatgacatg cggcttgatg ccattcctat caagacagcc aaggcctcca
     8761 gggacattgc aagtgacttc aagtacaagg aaggctaccg taagcagctg ggccaccaca
     8821 ttggtgcccg tggtatacat gatgacccca agatgatgtg gtccatgcac gtagccaaga
     8881 tccagagtga cagggagtac aagaaggact ttgagaagtg gaagaccaag tatagcagcc
     8941 cagtggacat gctgggagtg gtgctggcca agaagtgcca gaccttggtc agcgatgctg
     9001 actacaggaa ctacctacat cagtggacat gcctccctga ccagaatgac gtcatccatg
     9061 ctcggcaggc ttatgatctc cagagcgata atatgtacaa gtctgacctc cagtggatga
     9121 gaggcatcgg ctgggtgccc attggctctt tggatgtgga aaaatgcaaa cgggccactg
     9181 aaatcttgag tgacaaaatc taccgtcagc ccccagacaa gttcaagttt accagtgtga
     9241 ctgattctct ggagcaagta ttggccaaga ataatgccat cactatgaac aagcgtttgt
     9301 acacagaagc ctgggacaaa gacaagacgc aaatccacat catgccagat acaccagaaa
     9361 tcatgttggc gcgaatgaat aaagtcaact acagcgagag tctgtataaa cttgccaatg
     9421 aagaagcaaa gaaaaaaggc tatgacttac gaagtgatgc catccctatt gtggcagcca
     9481 aggcctccag agacatcgcc agtgactaca aatacaaaga tggctaccgc aagcagctgg
     9541 gccaccatat tggggctcgg aacatcaaag atgaccccaa gatgatgtgg tccatgcacg
     9601 tggccaagat ccagagtgac agggagtaca agaaggactt tgagaagtgg aagaccaagt
     9661 atagcagccc agtggacatg ctgggcgtgg tactggccaa gaagtgccag atccttgtaa
     9721 gcgacataga ctacaagcat cctctccatg agtggacatg cctgcctgac cagaatgatg
     9781 tcatccacgc tcggcaggcc tatgatctcc agagtgataa tgtgtacaag tcagatctcc
     9841 agtggatgag aggcattggc tgggttccca tcgggtctct ggatgtggtc aagtgtaaga
     9901 gagctgcaga gatcctgagc gacaacatct atcgccagcc tccaaacaag tttaagttca
     9961 ccagtgtgac tgattctctg gagcaggtgc tggccaagag caacgccctc aacatgaaca
    10021 agcgattata cacagaggcc tgggacaaag acaagattca aattcatgta atgcctgata
    10081 caccggagat tatgctggca aggcagaaca gaatcaacta cagcgagagt ctatataaac
    10141 tggccaatga agaagcaaag aagaaaggct atgacctgcg tgtcgatgct atccccattg
    10201 tggcggccaa ggcctccaga gatattgcca gtgactacaa atacaaagtt ggctaccgta
    10261 agcagctggg acaccacatt ggagcccgca acattgaaga tgaccccaag atgatgtggt
    10321 ccatgcacgt ggccaagatc cagagtgaca gggagtacaa gaaggacttt gagaaatgga
    10381 agactaagta tagcagccca gtggacatgc tgggggtggt attggccaag aagtgccaga
    10441 ccttggtcag cgatgtggac tacaggaact acctacacca gtggacatgt ctacctgacc
    10501 agaatgatgt catccacgct cggcaggcct atgatctcca gagtgataat gtgtacaagt
    10561 cagatctcca gtggatgaga ggcattggct gggtccccat cgggtctctg gatgtggtca
    10621 agtgtaagag agctgcagag atcctgagcg acaacatcta tcgccagcct ccaaacaagt
    10681 ttaagttcac cagtgtgact gattctctgg agcaggtgct ggccaagagc aacgccctca
    10741 acatgaacaa gcgcttgtac acagaagcct gggacaaaga caagacccag atccacatca
    10801 tgcctgatac accagaaatc atgttggcca gacaaaataa aataaactac agtgagagcc
    10861 tgtaccgcca ggccatggaa gaagctaaga aggaaggcta tgacttgaga agtgatgcca
    10921 ttcccattgt ggctgccaag gcttcccggg acattgctag tgattacaaa tacaaagaag
    10981 cctatcggaa gcagttgggt caccacattg gcgctagagc gatacatgat gatcccaaga
    11041 tgatgtggtc cctccacatt gccaaagtgc agagtgaccg tgagtataag aaagaatttg
    11101 agaaatacaa gacaagatac agcagccctg tggacatgct tggtattgtg ttggccaaga
    11161 aatgccaaac cttggtcagt gatgtggact acaaacaccc actgcacgaa tggacctgcc
    11221 tgccggacca gaatgatgtc atccaggccc ggaaagcata tgacctccag agtgataatc
    11281 tgtacaaggc agacctggaa tggatgaaag gcattggctg ggttcccatt ggttccttgg
    11341 aagttgtcaa agccaagagg gccacagaga tactgagtga caacatctac cgccagcgtc
    11401 ccgacacact gaaattcacc agtataaccg actcgctgga gcaggtgctg gcaaagaata
    11461 atgcaatcac catgaacaag cgactgtaca cggaagcctg ggacaatgac aagaaaacga
    11521 tccatgtcat gccagacacg ccagaaatca tgctggccaa actcaacagg ataaactaca
    11581 gcgataaact ctacaaagtg tctctggagg aggccaggag gcaaggctat gacctgcgcg
    11641 tggatgctat tcctatccga tcagccaagg catcaagaga gatcgctagt gattacaagt
    11701 acaaggaagg ctaccgcaaa cagctgggcc accacattgg tgctcggaac atcaaggatg
    11761 accccaagat gatgtggtcc atgcacgtgg ccaagatcca gagtgacagg gagtacaaga
    11821 aggactttga gaagtggaag accaagtata gcagcccagt ggacatgctg ggcgtggtgc
    11881 tggccaagaa gtgccagatc cttgtaagcg acatagacta caagcatcct ctccatgagt
    11941 ggacatgcct gcctgaccag aatgatgtca ttcaggcacg gaaggcctat gatcttcaga
    12001 gcgatgctgt gtacaaggct gatcttgagt ggctgagagg catcggatgg gttcccattg
    12061 gctctgtaga ggtcgagaag gtgaagagag caggtgaaat cctgagtgac aggaagtatc
    12121 gccagcctgc agaccagctg aagttcacat gtattacaga caccccagaa attgtcctgg
    12181 caaagagtaa tgccatcact atgagcaagc atttgtatac agaagcttgg gatgctgaca
    12241 aagcctccat ccatgtcatg ccagacaccc ctgaaatcct gctggccaag agcaattctg
    12301 ccaatatcag ccataaacta tataccaagg gatgggatga atcaaagatg aaggactatg
    12361 atctgagaga ggatgctatt tccatcaaaa gtgccaaggc ctccagggac attgccagtg
    12421 attacaaata taaggaagcc tatgaaaaac aaaaaggcca ccacatcgga gcccagagtg
    12481 tggaagatga tcccaggatc ctttgcgcca tgcacgcagg gaagatttac agtgacaggg
    12541 agtacaagaa ggaattccag aaatggaaga ccaagttcag cagcccagtg gacatgctgg
    12601 gggtggtgct ggccaagaag tgccagacct tggtcagcga tgtggactac aggaactacc
    12661 tgcacaactg gacttgcctg cctgaccaga acgacattat tcaagcaaag aaggcctacg
    12721 aactgcagag tgatagtgtg tataaagcag atctggagtg gctgcgtggc attggctgga
    12781 tgccggaagg ctccatagaa atgaccagag tgaagggcgc ccaagacctt gtgaatgaga
    12841 gactgtatag gacacgacca gaagccttga agtttacctc cattgttgat actccagaag
    12901 ttgtcctggc aaaagccaat tctctgcaaa tgagtgagag gctgtatcag gaagcctgga
    12961 ataaggataa aaccaatatc agccttccct tggacacccc agcgatgcta caggcccaaa
    13021 tcaatgcctt gcagattagc aataaactct atcaaaaaga ctgggatgaa gccaagcaga
    13081 aaggctacga cttgcgagca gatgccattg aaatcaagca tgccaaagcc tccagggaga
    13141 tcgccagtga gtacaaatac aaagaaggtt acagaaagca gctgggccac cacgtgggtt
    13201 tccgcagcct gcaagatgac cccaagttgg tatggtctat acatgctgct aagatccaga
    13261 gtgacagaga atacaagaaa gcctatgaga agtcgaaagg catttacaac acacccttgg
    13321 atatgatgtc aattgttcaa gccaagaaat gccaagtcct ggtcagcgac gttgattatc
    13381 gcaattacct gcaccagtgg acgtgcctgc cggatcagaa cgatgtgatc caggctaaga
    13441 aagcctacga gctgcagagc gatgccatct acaaggctga cctggagtgg ctgcgtggca
    13501 ttggctggat gccagaaggg tctcctgaag tcctgagagt caaaaatgcc caggagatcc
    13561 tctgtgacag tgtctaccgg acccccgtgg tgaagctcaa gtacacaagt attgtggaca
    13621 cacccgaagt tgtccttgct aagtcaaatg ctgaaaatat tagcattcca aaatacagag
    13681 aagtttggga caaagataaa acttccatcc acataatgcc agacacgcct gaaattaatc
    13741 tcgctcgagc aaacgctctt aatgtgagca ataaactcta ccgtgagggg tgggatgaag
    13801 tcaagatgag ctgtgatgtc cggttggatg ctatccccat ccaggctgcc aaggcctcca
    13861 gggagattgc cagtgactat aaatacaagc ttgaccatga gaagcagaag ggacactacg
    13921 tgggcaccct cacagccagg gatgacaaca agatccggtg ggccctcatc gctggcaaga
    13981 ttcagaatga aagggagtac aggctgcagt gggccaaatg gaagaccaag ttccagagcc
    14041 ccgtggacat gctttctatc ctgcattcga agaagtgcca gacgctggtc agcgacattg
    14101 actatcgcaa ttacctacac gagtggacgt gcatgcctga ccaaaacgat gtgatccagg
    14161 ccaagaaagc ctacgagctg cagagcgatg ctgtctacaa ggctgacttg gaatggttac
    14221 gtggaattgg gtggatgccg aatgattctg tctctgtcaa tcatgccaaa catgctgcag
    14281 atatcttcag tgagaaaaaa tatcgcacaa aaatagaaac tctcaacttc actcctgtgg
    14341 atgacagagt ggattatgtg acagcaaaac agagcagtga gatccgagat gatattaaat
    14401 atcgcaaaga ttggaatgcc atcaagtcaa agtataccct tacagaaacc ccactgctgc
    14461 acactgccca ggaggctgcc cggatcctgg accagtacct ctacaaggaa ggctgggaga
    14521 aacagaaagc cacaggctac attctgccac ccgatgctgt gccattcgtt catgcccatc
    14581 attccagcga tgttcaaagt gagctgaaat acaaagctga gcacgttaag cagcgaggcc
    14641 actacgttgg cgttcctaca atgagagacg atcccaagct ggtttggttt gagcacgcag
    14701 gccagattca gaacgacagg ctctacaagg agagctacca taagtcaaag gccaaaatca
    14761 atatccctgc tgacatggtg tcggttgtgg ccgccaagga agggcagaac cttgtcagtg
    14821 acatcgatta ccgtcaatac ctacaccagt ggacgtgcca ccctgaccaa aatgatgtta
    14881 ttcaggcaaa aattgcctat gaccttcaga gtgacaatgt ctacaaagct gacctggaat
    14941 ggctccgagg tattggctgg atccctctgg attctgtgga ccatgtgagg gttacaaaga
    15001 accaggaaat ggtgaatcag ataaaataca agaaagatgc tcttgccaac tatcccaact
    15061 ttacaagtgt ggaggaccct ccagagattg ttctagccaa gattaactca gtcaatcaaa
    15121 gtgatgtgaa atataaagaa acatttaata aagccaaggg caagtacata ttttctccag
    15181 acacaccata catctcccac tccaaagaca tggggaaact ctatagtact atactataca
    15241 agggagcctg ggagggcacc aaggcctatg gctacaccct ggatgagcgc tatattccaa
    15301 ttgttggagc caagcatgct gacctggtga acagtgagct taaatacaaa gaaacctatg
    15361 agaagcagaa aggtcactac ctggctggaa aagaaataag tgagtttcct ggtgtggtcc
    15421 actgcctgga tttccagcag atgcggagtg cgttgaacta cagaagagat tatgaagaca
    15481 ccaaagcaaa tgtgcatatt cccaatgaca tgatgaacca cgtgctggcg aagaggtgcc
    15541 agtatatcct cagtgacctg gagtaccgac actactttca tcagtggacg tcacttcccg
    15601 aggagcccaa tgttatccgc gcccgaaacg cccaggagat cttaagtgat aatgtatata
    15661 aagatgactt gaattggctg aagggcattg gctgctatgt ttgggacaca ccccagattc
    15721 tccatgccaa gaaatcatat gacctccaga gtcagctaca atacacagca gcaagtaaag
    15781 aaaatctgca gaactataac ctggtcacag atacgccagt ttacgtgact gctcttcaga
    15841 gtggcattaa tgccagtgag gtgaaatata aagaaaatta ccatcagatt aaggacaagt
    15901 acaccacagt gctagagacg gcagactacg acagaaccaa gcacctcaag agtctgtaca
    15961 gcagcaacat atacaaagag gcctgggata aggtgaaagc caccagctat aacctgccta
    16021 ccagcacctt gtccctgaca catgccaaga accagaagca cctggccagc catatcaaat
    16081 accgagaaga atatgaaaag ttcaaagccc tttacacatt accaaaaagt gttgacgacg
    16141 atccaaacac agcgcggtgt ctccgagtgg gcaaacttaa catcgaccgc ctgtacagat
    16201 cagtgtacga gaagaacaag atgaaaatca acatcgtgcc cgacatggtg gagatggtga
    16261 ctgccaagga ctctcagaag aaagtcagcg agatcgacta ccgcctgcac ctccatgagt
    16321 ggatttgcca ccctgactta caagtcaaca gtcacgtcag aaaagtgaca gaccagatca
    16381 gcgacattgt atacaaggat gacctcacct ggctgaaagg cattggttgc tacgtctggg
    16441 acactcctga aattctccat gcaaagcatg cttatgacct acgcaatgat atcaagtata
    16501 aagctcacgt gcagaagaca aggaatgact acaagctggt gactgacaca ccggtttacg
    16561 ttcaggcagt caagagtggg aagcagctga gtgatgctgt ctaccactat gactacgtgc
    16621 acagtgtcag aggcaaagtg gccccaacta caaaaacggt ggatctggac cgggccctcc
    16681 atgcatacaa gcttcagagt gagaatttgt acaagaaagg cctgcgcttc ctgcccactg
    16741 ggtacaggct ccctgttgat acccctcatt tcaatcacac caaggatacc cgctacatga
    16801 gcagctattt caaatacaaa gaagcctatg aacacatcaa ggcaaatggg tacacacttg
    16861 gacccaagga tgtcccgttt gtccatgtcc ggagagtcaa caacgttact agtgagagac
    16921 tatatcgaga actgtatcac aaactaaaag acaagataca tacaacccca gacacacctg
    16981 aaatccgcca agtcaagaag acacaagaag ctgtcagtga gttgatctac aaatcagact
    17041 tcttcaagat gcagggccac atgatctccc tgccgtatac accccaagtg ttgcactgtc
    17101 gctacgtggg agacatcacg agtgatatta aatacaaaga ggatctgcag atcttgaagg
    17161 ggcttggctg cttcctgtat gacactcctg acatggtccg ctcccggcac ctaaggaaac
    17221 tctggtcgaa ctacctgtac acggataatg ccaggaagat gagagacaaa tacaaagtgg
    17281 tgcttgacac cccagaatac agaaaagtgc aggaactgaa gacgcatctg agtgagctgg
    17341 tgtacagagc ctcaggcaag aagcagaagt ccatcttcac ttcagttcct gatacccctg
    17401 accttctaag agccaagcga ggacagaagc ttcagagtca gtatctctat gttgaacttg
    17461 ctactaaaga gagacctcat caccatgctg gaaatcagac cacagctttg caacacgcta
    17521 aagacgtgaa ggacatggtc agcgagaaaa agtacaagat tcaatatgaa aagatgaaag
    17581 acaagtatac accagttgca gacacaccaa tcctcatcag agccaagaga gcttactgga
    17641 acgccagtga tcttcgctac aaagaaacat ttcaaaagac taaagggaga tatcacacag
    17701 tgaaggacgc cctggacatt gtgtatcatc gcaaagtcac agacgacatc agtaaagtga
    17761 aatacaagga aaactacatg agccagctgg gaatctggag ctccatccct gatcgccctg
    17821 aacacttcca tcaccgggca gtcaccgatg ctgtcagcga tgtaaaatat aaagaagatt
    17881 tgacctggct taaaggcatt ggttgctatg cctatgatac ccctgacttg acgctagctg
    17941 aacagaacaa gactctctac agcaagtata agtataaaga agtatttgaa agaacaaagt
    18001 caaacttcaa gtatgttgct gactgtccaa ttaacaggca tttcaagtat gcaactcagt
    18061 tgatgaatga gaaaaaatac agagctgatt atgagcagcg gaaagataaa taccacctgg
    18121 tagtcgatga acctagacat ctgctggcta agaccgcagg cgaccagatc agccagatca
    18181 aatacaggaa aaagtatgag aagtcaaagg acaaattcac ctcggttgtg gacaccccag
    18241 agcacctgcg caccacaaaa gtcaacaagc aaatcagtga tatactttat aaactggaat
    18301 acaacaaggc cagaccaaga ggctacacca ccatccatga cacacccatg ctgctgcatg
    18361 tccgcaaagt gaaggatgaa gtcagcgatc tgaaatataa ggaagtttac caaagaaata
    18421 aatctaactg caccatcaag ccagatgctg ttcatatcaa agcagcgaaa gatgcctaca
    18481 aagtcaacac aaatctggac tacaagaaac agtacgaagc caataaagca tactggaagt
    18541 ggacgcccga ccgcccagac ttcatccagg cggccaagtc atctctccag cagagtgact
    18601 ttgaatataa gctggaccga gagtttctca agggctgcaa gctttctgtc actgacgata
    18661 aagacatggt gctggccctc aggaattcct taatagagag cgatctgaaa tacaaagaga
    18721 aacacgtaaa ggaaagagga agctgtcatg ctgtgcctga caccccacag atcctcttgg
    18781 cgaagactgt cagcaatctg gtgtctgaga acaagtacaa ggaccatgtc aagaagcacc
    18841 tggcccaagg ctcgtatacg accctgccag agaccaggga tacagttcac gtcaaggcag
    18901 tgaccaagca cgtcagtgat acaaactaca aaaagaagtt tgtcaaggag aaaggcaagt
    18961 ccaactactc catcatgcaa gagcctccag aggtgaagca cgccatggaa gtggctaaga
    19021 agcagagtga tgttgcctat aaaaaagatg ccaaagagaa tctgcattac accacagtgg
    19081 ctgaccggcc agacatcaag aaggccaccc aggcagccaa acaggccagt gaggtggagt
    19141 acagagccaa gcatcgcaag gaaggcagcc atgggttaag catgcttggc cgcccagaca
    19201 ttgaaatggc caagaaggca gccaagctga gcagccaggt taaataccgc gaaaattttg
    19261 acaaggagaa gggcaaaaca cccaaataca acccgaaaga cagccagctc tacaaaacta
    19321 tgaaagatgc caacaacctt gcaagcgagg tcaaatataa ggctgacctg aagaaactcc
    19381 acaaacctgt gactgacatg aaggagtctc tgataatgca ccacgtccta aatacaagcc
    19441 agctcgccag ttcttaccag tacaagaaga actatgagaa gagcaaaggc cactaccaca
    19501 caatacctga caacctggaa cagctacacc acagagaagc cacagagctg cagagtatcg
    19561 tgaaatacaa agaaaaatat gaaaaagaac gaggcaagcc catgctggac tttgagactc
    19621 caacatacat cactgccaaa gagtctcagc agatgcagag tgggaaagaa tataggaaag
    19681 attatgaaga gtccattaaa ggcagaaacc tgacgggcct ggaggtcacg ccagcattgt
    19741 tacatgtcag acatgcaacc aaaatagcaa gcgagaaaga gtataggaaa gacctggaag
    19801 aaagcatccg aggcagaggt ctcactgaga tggaagatac tcctgacatg ctgagagcca
    19861 agaatgccac tcagatcctc aatgagaaag aatataagcg agacctggag ctggaagtca
    19921 aaggaagagg cctgaatgcc atggccaacg agactccaga ttttatgcgg gccaggaatg
    19981 ctaccgacat tgccagccag attaagtaca agcaatcggc agaaatggaa aaggccaatt
    20041 ttacttctgt tgttgatacc ccagaaatta tccatgctca gcaagtgaag aacctttcca
    20101 gccagaaaaa gtacaaggaa gatgcagaga agtccatgtc atattatgag actgtcttgg
    20161 acacgccaga gatgcaaaga gtccgcgaga accagaagaa cttcagcctg cttcaatacc
    20221 agtgtgacct taaaaacagt aaagggaaaa ttacagttgt tcaagacacg ccagaaatac
    20281 tgcgtgttaa agaaaaccaa aagaatttca gctcggtttt atataaagag gatgtatccc
    20341 cggggacggc aattggaaag acgcctgaga tgctcagagt gaagcaaacg caggaccaca
    20401 ttagctcggt caagtataaa gaagcaatcg gacaaggaac tccgatccct gacctgcccg
    20461 aagtgaaacg cgtcaaggag acccagaagc acattagctc ggttatgtac aaagaaaacc
    20521 cgggaacagg catcccgacc actgtcactc cagagattga gagagtcaaa cgcaaccaag
    20581 agaactttag ctcggttttg tacaaagaaa gtttgggaaa aggaacccct acagctatca
    20641 ctccagagat ggagagagtc aaacgcaatc aagagaactt tagctcggtg ctatacaaag
    20701 agaacatggg caagggaacc cctttacctg tcactccaga gatggagaga gtcaaacaca
    20761 atcaagaaaa tattagctcg gttttgtaca aagaaaatgt ggggaaagcc accccaaccc
    20821 ctgtcactcc agagatgcag agagtcaaac gcaatcaaga aaacattagc tcggtgctat
    20881 acaaagagaa catggggaaa gcaaccccca cacccttcac tcctgagatg gaaagagtca
    20941 aacgcaatca agaaaacttt agctcggtat tgtacaaaga gaacatgaga aaagcaacac
    21001 caacgcctgt cactccagac atggagagag ccaaacgcaa ccaagaaaac attagctcgg
    21061 ttctttactc cgatagcttc cggaaacaaa tacaagggaa agctgcctat gtgctagata
    21121 caccagagat gaggcgggtt agggaaaccc aacggcacat ctcaacagtg aaatatcatg
    21181 aagactttga gaaacacaaa ggctgcttta caccagtggt gacagaccct atcactgaac
    21241 gagtaaagaa aaacacacag gacttcagtg acattaacta ccgaggtatt cagagaaaag
    21301 tggtggaaat ggaacaaaag cggaatgacc aggatcaaga taccattaca ggtctgcgtg
    21361 tctggcgtac taaccctggt tcagtttttg actatgatcc ggcagaagac aacattcaat
    21421 cccgaagtct gcacatgatt aatgtccaag ctcaacgccg gagccgggac cagtcaagat
    21481 ctgccagtgc actgagtatc agtgggggcg aggagaaatc tgagcactcc gaagctgcgg
    21541 accagcgcct ttccacatac agtgacggag gtgccttctt ctctgcaact tcaacagctt
    21601 acaaacatgt gaaaaccact cagctcccac agcaacggtc atcttcagtt gccacccagc
    21661 agacaacact gtcctctatc ccatcacacc cgtctactgc cgggaaaatc ttccgtgcta
    21721 tatatgacta tatagctgca gatgcggatg aagtgtcctt taaggatgga gatgctatag
    21781 tgaatgctca ggcgattgat gaaggctgga tgtatggcac tgtgcagaga actggcagga
    21841 ccggtatgct ccctgccaac tatgtggaag ctatttaagc acttcaagac ctccatcagt
    21901 ctgcagtatc tgcaactctg caggcaacat ttcagtggag acttcagtac accagggctt
    21961 tcaagctctc tcatgttttc acctgtagca atatcatttc atgtgttaca atctcttcta
    22021 tagaaaccat ggttactctc catgtataaa cttaccagca aatgacttac aaatatttta
    22081 cccaacatca attcatctgc tcagttctta aactagattt acagcttaat ttttttcccc
    22141 tggatttata catggaactg tagacagtaa acatgtaaaa atttactttc caaataagct
    22201 tttacattat gaactcttca gttttaaagt aaattcaaat tcacaataga attgttaaat
    22261 gcttctgtag tgttatgtaa ccaaaccagt ccttcccaat tataaaaaca tttgacatca
    22321 ttctgaacat ccaaactttg taaaagaaaa caagagaagc cctttccctt gtttactatg
    22381 tgttaatgct tgcgtttcat ttctgtaaga atgaacagtc aatatcaagt gttgagaaag
    22441 tagaaactaa taaaatctat agtactgaaa taaactgttc atgggcaac
//
