LOCUS       NM_001030274             540 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase core subunit S5
            (Ndufs5), mRNA.
ACCESSION   NM_001030274
VERSION     NM_001030274.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Di Michele,M., Attina,A., Roux,P.F., Tabet,I., Laguesse,S.,
            Florido,J., Houdeville,M., Choquet,A., Encislai,B., Arena,G., De
            Blasio,C., Wendling,O., Frenois,F.X., Papon,L., Stuani,L.,
            Fuentes,M., Jahannault Talignani,C., Rousseau,M., Guegan,J.,
            Buscail,Y., Dupre,P., Michaud,H.A., Rodier,G., Bellvert,F.,
            Kulyk,H., Ferraro Peyret,C., Mathieu,H., Close,P., Rapino,F.,
            Chaveroux,C., Pirot,N., Rubio,L., Torro,A., Sorg,T., Ango,F.,
            Hirtz,C., Compan,V., Lebigot,E., Legati,A., Ghezzi,D., Nguyen,L.,
            David,A., Sardet,C., Lacroix,M. and Le Cam,L.
  TITLE     E4F1 coordinates pyruvate metabolism and the activity of the
            elongator complex to ensure translation fidelity during brain
            development
  JOURNAL   Nat Commun 16 (1), 67 (2025)
   PUBMED   39747033
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   3  (bases 1 to 540)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 540)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 540)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   6  (bases 1 to 540)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 540)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU534760.1 and BC081434.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CN840205.1, BU530781.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN02415123
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BU534760.1         4-59
            57-540              BC081434.1         1-484
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 57.42 cM"
     gene            1..540
                     /gene="Ndufs5"
                     /note="NADH:ubiquinone oxidoreductase core subunit S5"
                     /db_xref="GeneID:595136"
                     /db_xref="MGI:MGI:1890889"
     exon            1..74
                     /gene="Ndufs5"
                     /inference="alignment:Splign:2.1.0"
     exon            75..292
                     /gene="Ndufs5"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..397
                     /gene="Ndufs5"
                     /EC_number="7.1.1.2"
                     /note="CI-15 kDa; NADH dehydrogenase (ubiquinone) Fe-S
                     protein 5; complex I-15 kDa; NADH-ubiquinone
                     oxidoreductase 15 kDa subunit"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] iron-sulfur
                     protein 5"
                     /protein_id="NP_001025445.1"
                     /db_xref="CCDS:CCDS18618.1"
                     /db_xref="GeneID:595136"
                     /db_xref="MGI:MGI:1890889"
                     /translation="MPFLDIQKKLGISLDRHFMFLSAEQPYKNAARCHAFEKEWIECA
                     HGIGGTRAKKECKIEFDDFEECLLRYKTMRRMHDIKKQREKLMKEGKYTPPPHHSGRE
                     EPRP"
     exon            293..509
                     /gene="Ndufs5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      488..493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufs5"
     polyA_site      509
                     /gene="Ndufs5"
ORIGIN      
        1 acggcaggcg tctgcgtcct cccgcagccg gcggtcggga attgcaccag ggacctgaca
       61 agggcactgc agagccatgc ctttccttga catacagaaa aagctgggca tcagcctgga
      121 ccggcacttt atgttcctaa gcgcagaaca gccctataag aacgccgctc ggtgccacgc
      181 atttgaaaaa gagtggatag agtgtgcaca cgggatcggt gggacccggg cgaaaaagga
      241 gtgcaagata gagttcgatg acttcgaaga gtgcttgctt cggtacaaaa cgatgaggcg
      301 aatgcatgat atcaagaaac agcgggagaa gctaatgaaa gagggcaaat acacccctcc
      361 acctcaccat tcgggcaggg aggagcccag gccctgagcg gggcagctgg aggccgctgt
      421 catgctctgt tttcccctgg agagaatatt taaggaaagc tccttcatta agtattaagt
      481 atgtggaaat aaagaattac tcagtcttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
