LOCUS       NM_025523                410 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit C1 (Ndufc1),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_025523
VERSION     NM_025523.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Chen,Y., Wu,J., Zhang,S., Gao,W., Liao,Z., Zhou,T., Li,Y., Su,D.,
            Liu,H., Yang,X., Su,P. and Xu,C.
  TITLE     Hnrnpk maintains chondrocytes survival and function during growth
            plate development via regulating Hif1alpha-glycolysis axis
  JOURNAL   Cell Death Dis 13 (9), 803 (2022)
   PUBMED   36127325
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 410)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 410)
  AUTHORS   Varum,S., Baggiolini,A., Zurkirchen,L., Atak,Z.K., Cantu,C.,
            Marzorati,E., Bossart,R., Wouters,J., Hausel,J., Tuncer,E.,
            Zingg,D., Veen,D., John,N., Balz,M., Levesque,M.P., Basler,K.,
            Aerts,S., Zamboni,N., Dummer,R. and Sommer,L.
  TITLE     Yin Yang 1 Orchestrates a Metabolic Program Required for Both
            Neural Crest Development and Melanoma Formation
  JOURNAL   Cell Stem Cell 24 (4), 637-653 (2019)
   PUBMED   30951662
REFERENCE   5  (bases 1 to 410)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 410)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 410)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   8  (bases 1 to 410)
  AUTHORS   Jiang,C.H., Tsien,J.Z., Schultz,P.G. and Hu,Y.
  TITLE     The effects of aging on gene expression in the hypothalamus and
            cortex of mice
  JOURNAL   Proc Natl Acad Sci U S A 98 (4), 1930-1934 (2001)
   PUBMED   11172053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC105966.11.
            
            On Jan 12, 2022 this sequence version replaced NM_025523.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028011.1, BU555460.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                AC105966.11        145246-145320       c
            76-179              AC105966.11        144527-144630       c
            180-256             AC105966.11        143718-143794       c
            257-410             AC105966.11        141848-142001       c
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 22.47 cM"
     gene            1..410
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /note="NADH:ubiquinone oxidoreductase subunit C1"
                     /db_xref="GeneID:66377"
                     /db_xref="MGI:MGI:1913627"
     exon            1..75
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..239
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /note="NADH dehydrogenase [ubiquinone] 1 subunit C1,
                     mitochondrial; complex I-KFYI; NADH-ubiquinone
                     oxidoreductase KFYI subunit; NADH dehydrogenase
                     (ubiquinone) 1, subcomplex unknown, 1"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 subunit C1,
                     mitochondrial precursor"
                     /protein_id="NP_079799.1"
                     /db_xref="CCDS:CCDS38426.1"
                     /db_xref="GeneID:66377"
                     /db_xref="MGI:MGI:1913627"
                     /translation="MAPSVVLRSFSRLLAPARLPSCSSTRSKFYVREPVNAKPNWLAV
                     GLSVGASVFMWIYLIQTHNEDVLEYKRRNGLE"
     exon            76..179
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /inference="alignment:Splign:2.1.0"
     exon            180..256
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /inference="alignment:Splign:2.1.0"
     exon            257..410
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      376..381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /note="hexamer: AATAAA"
     polyA_site      410
                     /gene="Ndufc1"
                     /gene_synonym="2310016K22Rik; CI-KFYI; KFYI"
                     /note="major polyA site"
ORIGIN      
        1 ggaacaagat ggcgccgtcc gtagtgctgc gctcgttttc gcggctgctg gcccccgccc
       61 ggctgccgag ctgctcttca acacggtcga agttctatgt ccgggagcca gtcaatgcca
      121 aacctaactg gttggcagtt ggactgtccg tgggcgcctc ggttttcatg tggatttatc
      181 tcatccaaac acacaatgaa gatgttttgg agtataaaag aagaaatgga ttggaataaa
      241 ctttggaaat aatacagtca gcttcatgtg atgatcacag tccttcctct ggattcaccc
      301 tcagtgacgg atgtgagaaa agagttacat gcgaatatga gtcagtcaac acgttttgca
      361 tggttaagtt aaagaaataa aaatactcgc gctcctcatg tgtagacgga
//
