LOCUS       NM_025843                533 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit B7 (Ndufb7),
            mRNA.
ACCESSION   NM_025843 XM_907064
VERSION     NM_025843.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 533)
  AUTHORS   Milenkovic,D., Misic,J., Hevler,J.F., Molinie,T., Chung,I.,
            Atanassov,I., Li,X., Filograna,R., Mesaros,A., Mourier,A.,
            Heck,A.J.R., Hirst,J. and Larsson,N.G.
  TITLE     Preserved respiratory chain capacity and physiology in mice with
            profoundly reduced levels of mitochondrial respirasomes
  JOURNAL   Cell Metab 35 (10), 1799-1813 (2023)
   PUBMED   37633273
REFERENCE   3  (bases 1 to 533)
  AUTHORS   Ponce,J.M., Coen,G., Spitler,K.M., Dragisic,N., Martins,I.,
            Hinton,A. Jr., Mungai,M., Tadinada,S.M., Zhang,H., Oudit,G.Y.,
            Song,L.S., Li,N., Sicinski,P., Strack,S., Abel,E.D., Mitchell,C.,
            Hall,D.D. and Grueter,C.E.
  TITLE     Stress-Induced Cyclin C Translocation Regulates Cardiac
            Mitochondrial Dynamics
  JOURNAL   J Am Heart Assoc 9 (7), e014366 (2020)
   PUBMED   32248761
REFERENCE   4  (bases 1 to 533)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 533)
  AUTHORS   Yavari,A., Stocker,C.J., Ghaffari,S., Wargent,E.T., Steeples,V.,
            Czibik,G., Pinter,K., Bellahcene,M., Woods,A., Martinez de
            Morentin,P.B., Cansell,C., Lam,B.Y., Chuster,A., Petkevicius,K.,
            Nguyen-Tu,M.S., Martinez-Sanchez,A., Pullen,T.J., Oliver,P.L.,
            Stockenhuber,A., Nguyen,C., Lazdam,M., O'Dowd,J.F., Harikumar,P.,
            Toth,M., Beall,C., Kyriakou,T., Parnis,J., Sarma,D., Katritsis,G.,
            Wortmann,D.D., Harper,A.R., Brown,L.A., Willows,R., Gandra,S.,
            Poncio,V., de Oliveira Figueiredo,M.J., Qi,N.R., Peirson,S.N.,
            McCrimmon,R.J., Gereben,B., Tretter,L., Fekete,C., Redwood,C.,
            Yeo,G.S., Heisler,L.K., Rutter,G.A., Smith,M.A., Withers,D.J.,
            Carling,D., Sternick,E.B., Arch,J.R., Cawthorne,M.A., Watkins,H.
            and Ashrafian,H.
  TITLE     Chronic Activation of gamma2 AMPK Induces Obesity and Reduces beta
            Cell Function
  JOURNAL   Cell Metab 23 (5), 821-836 (2016)
   PUBMED   27133129
REFERENCE   6  (bases 1 to 533)
  AUTHORS   Dai,N., Zhao,L., Wrighting,D., Kramer,D., Majithia,A., Wang,Y.,
            Cracan,V., Borges-Rivera,D., Mootha,V.K., Nahrendorf,M.,
            Thorburn,D.R., Minichiello,L., Altshuler,D. and Avruch,J.
  TITLE     IGF2BP2/IMP2-Deficient mice resist obesity through enhanced
            translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial
            proteins
  JOURNAL   Cell Metab 21 (4), 609-621 (2015)
   PUBMED   25863250
REFERENCE   7  (bases 1 to 533)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 533)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   9  (bases 1 to 533)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151992.3.
            
            On Apr 29, 2007 this sequence version replaced NM_025843.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003300.1, BY703189.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               AC151992.3         80427-80599         c
            174-342             AC151992.3         76359-76527         c
            343-533             AC151992.3         75734-75924         c
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 40.22 cM"
     gene            1..533
                     /gene="Ndufb7"
                     /gene_synonym="1110002H15Rik"
                     /note="NADH:ubiquinone oxidoreductase subunit B7"
                     /db_xref="GeneID:66916"
                     /db_xref="MGI:MGI:1914166"
     exon            1..173
                     /gene="Ndufb7"
                     /gene_synonym="1110002H15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..475
                     /gene="Ndufb7"
                     /gene_synonym="1110002H15Rik"
                     /note="CI-B18; complex I-B18; NADH-ubiquinone
                     oxidoreductase B18 subunit; NADH dehydrogenase
                     (ubiquinone) 1 beta subcomplex, 7"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 7"
                     /protein_id="NP_080119.1"
                     /db_xref="CCDS:CCDS22455.1"
                     /db_xref="GeneID:66916"
                     /db_xref="MGI:MGI:1914166"
                     /translation="MGAHLTRRYLWDASVEPDPEKIPSFPPDLGFPERKERVMVATQQ
                     EMMDAQLTLQQRDYCAHYLIRLLKCKRDSFPNFLACKHEQHDWDYCEHLDYVKRMKEF
                     ERERRLLQRKKRRALKEARVAQGQGEGEVGPEVAL"
     exon            174..342
                     /gene="Ndufb7"
                     /gene_synonym="1110002H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            343..533
                     /gene="Ndufb7"
                     /gene_synonym="1110002H15Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgcttcca ggtgggagcg aggtgacccc ggctactaaa gaagggtaag gcagagtagc
       61 catgggggcg cacctgaccc ggcgctatct gtgggatgcc tcggtggagc ctgaccccga
      121 gaagataccc agcttcccgc cggacctcgg ctttccggag cgcaaggagc gagtgatggt
      181 ggccacacaa caagagatga tggatgccca gctgacactg cagcaacgtg actactgtgc
      241 ccactacctc atccggctgc tgaagtgcaa gcgagacagc ttccccaact tcctggcctg
      301 caagcacgag cagcacgact gggactactg cgagcacctg gattacgtga aacgcatgaa
      361 ggagtttgaa cgtgagcggc gactgctcca aaggaagaag cgaagggcac tgaaggaagc
      421 acgggtagcc caaggccagg gagaaggaga ggtgggccct gaggtggccc tgtagggatt
      481 acccgccagc ctgtggacct atcagtgaaa taaaagcttt gggtcacctg cct
//
