LOCUS       NM_026610                505 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit B4 (Ndufb4),
            mRNA.
ACCESSION   NM_026610
VERSION     NM_026610.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 505)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 505)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 505)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 505)
  AUTHORS   Li,X.Y., Cui,X.S. and Kim,N.H.
  TITLE     Transcription profile during maternal to zygotic transition in the
            mouse embryo
  JOURNAL   Reprod Fertil Dev 18 (6), 635-645 (2006)
   PUBMED   16930510
REFERENCE   6  (bases 1 to 505)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129539.11.
            
            On Feb 28, 2022 this sequence version replaced NM_026610.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU562956.1, BY702780.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-238               AC129539.11        183647-183884
            239-385             AC129539.11        188904-189050
            386-505             AC129539.11        190345-190464
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 26.43 cM"
     gene            1..505
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /note="NADH:ubiquinone oxidoreductase subunit B4"
                     /db_xref="GeneID:68194"
                     /db_xref="MGI:MGI:1915444"
     exon            1..238
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..448
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /note="NADH:ubiquinone oxidoreductase B15 subunit; complex
                     I-B15; NADH dehydrogenase (ubiquinone) 1 beta subcomplex
                     4"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 4"
                     /protein_id="NP_080886.1"
                     /db_xref="CCDS:CCDS28161.1"
                     /db_xref="GeneID:68194"
                     /db_xref="MGI:MGI:1915444"
                     /translation="MSGSKYKPAPLATLPSTLDPAEYDVSPETRRAQVERLSIRARLK
                     REYLLQYNDPKRVSHIEDPALIRWTYARSANIYPNFRPTPKNSLLGAVAGFGPLIFWY
                     YVFKTDRDRKERLIQEGKLDRKFNISY"
     exon            239..385
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /inference="alignment:Splign:2.1.0"
     exon            386..505
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      477..482
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /note="hexamer: AATAAA"
     polyA_site      505
                     /gene="Ndufb4"
                     /gene_synonym="0610006N12Rik; 1300010H20Rik; CI-B15"
                     /note="major polyA site"
ORIGIN      
        1 agactcgaga gggcagccct catatccgcg caggcgcaga tgtgcgccgg gagtcaagat
       61 gtcgggttcc aagtataagc ctgcgcccct ggccactctc cccagtaccc tcgaccctgc
      121 cgagtatgac gtgtctccgg agaccagaag ggcgcaggtc gagcgcttga gcataagggc
      181 ccggcttaaa cgggagtatc tgcttcagta caacgacccc aaacgcgtgt cgcacatcga
      241 ggatcctgcc ttgattcgct ggacctatgc aagatcagca aatatttatc ctaatttcag
      301 gcccactccc aagaactcac ttttaggagc tgtggcaggg tttgggcccc tcatcttctg
      361 gtattatgtt ttcaaaacag acagggacag aaaggaaaga cttatccagg aaggaaaact
      421 ggacagaaaa tttaacatct cctactaagt tcggcaagga tgactattct tgcataaata
      481 aatctcctat taattaatca ccgaa
//
