LOCUS       NM_025597                769 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit B3 (Ndufb3),
            mRNA.
ACCESSION   NM_025597
VERSION     NM_025597.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 769)
  AUTHORS   Minati,M.A., Assi,M., Libert,M., Cordi,S., Lemaigre,F. and
            Jacquemin,P.
  TITLE     KRAS protein expression becomes progressively restricted during
            embryogenesis and in adulthood
  JOURNAL   Front Cell Dev Biol 10, 995013 (2022)
   PUBMED   36238685
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 769)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 769)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 769)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 769)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC118698.7, BC028669.1 and CK621544.1.
            
            On Aug 27, 2015 this sequence version replaced NM_025597.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK621544.1, CA456626.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AC118698.7         152435-152480
            47-708              BC028669.1         1-662
            709-769             CK621544.1         466-526
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 29.13 cM"
     gene            1..769
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /note="NADH:ubiquinone oxidoreductase subunit B3"
                     /db_xref="GeneID:66495"
                     /db_xref="MGI:MGI:1913745"
     exon            1..274
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /inference="alignment:Splign:2.1.0"
     exon            275..434
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..591
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /note="complex I-B12; NADH-ubiquinone oxidoreductase B12
                     subunit; NADH dehydrogenase (ubiquinone) 1 beta subcomplex
                     3"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 3"
                     /protein_id="NP_079873.1"
                     /db_xref="CCDS:CCDS14977.1"
                     /db_xref="GeneID:66495"
                     /db_xref="MGI:MGI:1913745"
                     /translation="MAAGHGHEHGHEHGHGHGKMELPDYRQWKIEGTPLETVQKKLAA
                     RGLRDPWARNEAWRYMGGFAGNITFPSVILKGFKWGFAAFVVALGAEYFLDSQNGDKK
                     HH"
     exon            435..750
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      689..694
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /note="hexamer: AATAAA"
     polyA_site      708
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /note="major polyA site"
     regulatory      726..731
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /note="hexamer: AATAAA"
     regulatory      732..737
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
                     /note="hexamer: ATTAAA"
     polyA_site      744
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
     polyA_site      750
                     /gene="Ndufb3"
                     /gene_synonym="2700033I16Rik; CI-B12"
ORIGIN      
        1 gtcctggagc aagacaaaca cggctttatc gtccttctcc tcaatatctt ctacctcaag
       61 cagactccag ctgcaaagtg tgggaaataa tctctacttc caggctcctt catgtcatct
      121 ctacgttgtc tgggagcctt gcgccagtac cggaacgttt accatctccc ccattttcct
      181 gtcgtaagaa actagaggaa acaacgtccg tttccggttg tctccggctg taaggttgaa
      241 tattgagtgt cccgggaggt cagattgctg tcagacatgg ctgctggaca tggacatgaa
      301 catggacatg aacatggaca tggccatggt aaaatggaac ttccagatta cagacagtgg
      361 aaaattgaag ggacgccatt agaaacggtg cagaagaagc ttgctgcccg agggctgagg
      421 gatccatggg ctcgcaatga ggcttggaga tacatgggcg gctttgcagg caacatcacc
      481 ttcccgagtg taatattaaa aggattcaaa tgggggtttg ctgcgtttgt ggtagctttg
      541 ggggctgaat atttcctgga ttcccagaat ggtgataaga agcatcactg aagagagcgc
      601 cttgtgacgt ctcttccata aaaataagat tctctcactg tagcattctt ggctgtatgt
      661 ttgtccttga aagaatatta tatggtttaa taaagtaaga aaaactgttg tttttgtaac
      721 tcttaaataa aattaaaaag aaaactgtaa aaaaaaaaaa aaaaaaaaa
//
