LOCUS       NM_001358797             841 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit B2 (Ndufb2),
            transcript variant 2, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001358797 XM_006506529
VERSION     NM_001358797.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 841)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 841)
  AUTHORS   Yao,Y., Liu,Q., Adrianto,I., Wu,X., Glassbrook,J., Khalasawi,N.,
            Yin,C., Yi,Q., Dong,Z., Geissmann,F., Zhou,L. and Mi,Q.S.
  TITLE     Histone deacetylase 3 controls lung alveolar macrophage development
            and homeostasis
  JOURNAL   Nat Commun 11 (1), 3822 (2020)
   PUBMED   32732898
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 841)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 841)
  AUTHORS   Dai,N., Zhao,L., Wrighting,D., Kramer,D., Majithia,A., Wang,Y.,
            Cracan,V., Borges-Rivera,D., Mootha,V.K., Nahrendorf,M.,
            Thorburn,D.R., Minichiello,L., Altshuler,D. and Avruch,J.
  TITLE     IGF2BP2/IMP2-Deficient mice resist obesity through enhanced
            translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial
            proteins
  JOURNAL   Cell Metab 21 (4), 609-621 (2015)
   PUBMED   25863250
REFERENCE   5  (bases 1 to 841)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122345.4 and AK028334.1.
            
            On Dec 9, 2017 this sequence version replaced XM_006506529.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028334.1, BU843358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 AC122345.4         182295-182303
            10-841              AK028334.1         1-832
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 18.42 cM"
     gene            1..841
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /note="NADH:ubiquinone oxidoreductase subunit B2"
                     /db_xref="GeneID:68198"
                     /db_xref="MGI:MGI:1915448"
     exon            1..148
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..368
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
                     subunit 2, mitochondrial; complex I-AGGG; NADH-ubiquinone
                     oxidoreductase AGGG subunit; NADH dehydrogenase
                     (ubiquinone) 1 beta subcomplex, 2"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 2, mitochondrial precursor"
                     /protein_id="NP_001345726.1"
                     /db_xref="CCDS:CCDS20025.1"
                     /db_xref="GeneID:68198"
                     /db_xref="MGI:MGI:1915448"
                     /translation="MSALTRLVPFGRVGGRLLRGCRARAAGDSGVRHAGGGVHIQPRY
                     REFPQLTRSQVIQGEFLSSLMWFWILWRFWHDSDAVLGHFSYPDPSQWTDEELGIPPD
                     DED"
     exon            149..293
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /inference="alignment:Splign:2.1.0"
     exon            294..389
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /inference="alignment:Splign:2.1.0"
     exon            390..841
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /inference="alignment:Splign:2.1.0"
     regulatory      439..444
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /note="hexamer: ATTAAA"
     polyA_site      462
                     /gene="Ndufb2"
                     /gene_synonym="1810011O01Rik; 8kDa; AGGG; CI-AGGG"
                     /note="major polyA site"
ORIGIN      
        1 gggactcggg gaagtgacgc atcaggggtg ggaactgcag tcttgctagt atgtctgcgc
       61 tcacccgtct ggtacctttc ggccgcgtcg gaggccgcct gctccggggc tgccgcgcgc
      121 gggcggctgg agacagtgga gtccgtcacg ctggcggtgg tgtacatatt cagccccggt
      181 acagggagtt tccccagctt acccggtccc aggtgatcca gggtgagttc ttaagctcac
      241 tcatgtggtt ctggattctt tggcgatttt ggcatgactc ggatgctgtg ctgggtcact
      301 tttcatatcc agatccttca cagtggacag atgaagaact gggaatccct cctgatgacg
      361 aggactgaca ctgtaaactc tctggacgag agcaaggtga gacatttcaa gaaattacag
      421 acttcattaa aggtgtaaat taaagtggct tgccaaaaac gaggaactga gttatgtttc
      481 tgatgacaac tgtcctttat ttcctatcct ctaactgctt gctggtccag tggtttgtgc
      541 cctttcagct gaccctctcg ggtcccctat gatgtaggta gatgttcttt gaggctatca
      601 aggaccacgg agattgtttc ttgcttagca tcactcactt gttaggttac ctatgactcc
      661 aaagcttacg tataacttaa gtaccatgcc tctgcctcgt gtgctgacag gtgatgtgac
      721 catatagatg ctccagagat tgttgcccca gaggttaggg gtcagaagag tccattgctt
      781 tccaagtggc ctcttgtagg actcataagt cacgtgtgac ttagaacttc ttagggatgg
      841 a
//
