LOCUS       NM_028611               2303 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase complex assembly factor
            7 (Ndufaf7), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_028611
VERSION     NM_028611.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2303)
  AUTHORS   Zurita Rendon,O., Silva Neiva,L., Sasarman,F. and Shoubridge,E.A.
  TITLE     The arginine methyltransferase NDUFAF7 is essential for complex I
            assembly and early vertebrate embryogenesis
  JOURNAL   Hum Mol Genet 23 (19), 5159-5170 (2014)
   PUBMED   24838397
  REMARK    GeneRIF: NDUFAF7 functions to methylate NDUFS2 after it assembles
            into a complex I, stabilizing an early intermediate in the assembly
            pathway, and that this function is essential for normal vertebrate
            development.
REFERENCE   2  (bases 1 to 2303)
  AUTHORS   Boon,A.C., deBeauchamp,J., Hollmann,A., Luke,J., Kotb,M., Rowe,S.,
            Finkelstein,D., Neale,G., Lu,L., Williams,R.W. and Webby,R.J.
  TITLE     Host genetic variation affects resistance to infection with a
            highly pathogenic H5N1 influenza A virus in mice
  JOURNAL   J Virol 83 (20), 10417-10426 (2009)
   PUBMED   19706712
REFERENCE   3  (bases 1 to 2303)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX236822.1, AK010752.1, CF617214.1 and AC154274.1.
            
            On Oct 31, 2007 this sequence version replaced NM_028611.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.149680.1, AK010752.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               CX236822.1         1-291
            292-1750            AK010752.1         291-1749
            1751-2243           CF617214.1         103-595
            2244-2303           AC154274.1         128490-128549
FEATURES             Location/Qualifiers
     source          1..2303
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 49.67 cM"
     gene            1..2303
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="NADH:ubiquinone oxidoreductase complex assembly
                     factor 7"
                     /db_xref="GeneID:73694"
                     /db_xref="MGI:MGI:1920944"
     exon            1..67
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..1341
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /EC_number="2.1.1.320"
                     /note="protein midA homolog, mitochondrial; NADH
                     dehydrogenase [ubiquinone] complex I, assembly factor 7;
                     protein arginine methyltransferase NDUFAF7, mitochondrial;
                     NADH dehydrogenase (ubiquinone) 1 alpha subcomplex
                     assembly factor 7"
                     /codon_start=1
                     /product="protein arginine methyltransferase NDUFAF7,
                     mitochondrial precursor"
                     /protein_id="NP_082887.2"
                     /db_xref="CCDS:CCDS28982.1"
                     /db_xref="GeneID:73694"
                     /db_xref="MGI:MGI:1920944"
                     /translation="MNALVRRCVARAGLPCIWRGKCYSSGNEPAESNQVTPMLRHLMY
                     KIKSTGPITVAEYMKEVLTNPAKGYYVHQDMLGEKGDFITSPEISQIFGELLGVWFVS
                     EWIASGKSPAFQLVELGPGRGTLTADILRVFSQLGSVLKTCAISIHLVEVSQKLSEIQ
                     ALTLAEEKVPLERDAESLVYMKGVTKSGIPVSWYRDLKDVPEGYSLYLAHEFFDVLPV
                     HKFQKTPRGWREVFVDVDPQASDKLRFVLAPCATPAEAFIQRDERREHVEVCPDAGVI
                     IQELSQRIASTGGAALIADYGHDGTKTDTLRGFYGHQLHDVLIAPGTADLTADVDFSY
                     LRRMAQGKVASLGPVEQRTFLKNMGIDVRLKVLLDKAGEPSAKQQLLGGYDMLMNPQK
                     MGERFHFFALLPHQRLHGGSQERNACQSKTPSSSVAGFDELVWQ"
     exon            68..231
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            232..312
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            313..423
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            424..637
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            638..696
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            697..807
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            808..951
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1125
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..2303
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1387..1392
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="hexamer: AATAAA"
     regulatory      1391..1396
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="hexamer: AACAAA"
     polyA_site      1408
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="major polyA site"
     polyA_site      1419
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="major polyA site"
     regulatory      1734..1739
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="hexamer: AGTAAA"
     polyA_site      1755
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
     regulatory      2166..2171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="hexamer: AATAAA"
     polyA_site      2188
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
     regulatory      2215..2220
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
                     /note="hexamer: AATAAA"
     polyA_site      2238
                     /gene="Ndufaf7"
                     /gene_synonym="2410091C18Rik; PRO1853"
ORIGIN      
        1 cggggcggag cctggcctcg gggtgtagga atgaatgctt tggtgagacg ctgcgtggcc
       61 cgcgcgggcc ttccctgtat ttggagaggg aaatgctaca gctccgggaa tgagccggca
      121 gaaagcaacc aggtgacacc gatgctgcgg catcttatgt acaaaataaa gtctacaggt
      181 cccatcactg tggccgagta catgaaggag gttttgacta acccagccaa gggatattat
      241 gtgcatcagg atatgctagg agaaaaagga gactttatta cttcacctga aataagccaa
      301 atcttcgggg agctactagg ggtgtggttt gttagtgaat ggatagcctc tggaaaaagc
      361 ccagcattcc agctggtgga acttggccct ggtcggggca ccctcacagc agatattttg
      421 agggtgttca gtcagcttgg gtctgtgcta aagacctgtg ccatctcaat acaccttgta
      481 gaggtgagcc agaaactaag tgagatccaa gcactgacac tggctgagga gaaggtccca
      541 ttggagagag acgctgaatc cctggtgtac atgaaaggtg tcacaaagtc tgggattcca
      601 gtctcctggt accgagacct gaaggatgtt cctgaaggat acagcttgta cctcgcccat
      661 gagttttttg atgttcttcc tgtgcataaa tttcagaaaa caccacgcgg atggagagaa
      721 gtgtttgttg atgtcgaccc acaagcttct gataaactga ggttcgtctt ggcgccttgt
      781 gcgacccctg cagaagcctt cattcaacgt gatgaaagga gggaacatgt ggaagtatgt
      841 cccgatgctg gggttatcat ccaagaactg tcccagcgca ttgcgtcaac tggaggtgca
      901 gccctgattg cggattacgg tcacgatggc acaaagacag acaccttgag agggttttat
      961 ggacaccagc ttcacgatgt cttaatcgct cctggaacag cagacctgac agctgatgtg
     1021 gacttcagtt acctgcgcag aatggcacaa ggaaaagtag cctctctggg tccagtggaa
     1081 cagcgaacat ttttaaaaaa catgggcatt gatgtccggc tgaaggttct cttggataaa
     1141 gcaggtgagc catctgcgaa gcagcagcta cttggagggt atgatatgtt aatgaatcct
     1201 cagaagatgg gagaaagatt tcacttcttt gccttgctac ctcatcagag acttcatggg
     1261 gggagtcaag aaaggaatgc ctgccagtca aaaaccccct cctcctctgt agctgggttt
     1321 gatgaacttg tttggcagtg atacttcagc ttgaactttt attcctcagt gggccttaaa
     1381 aatcaaaata aacaaaattc actttgcata ttgaagtaac ataagttttc aaactagtat
     1441 ctcttttcag tcaataaaaa tagcctgttt atgctgggca gtggtggcgc atgcctttaa
     1501 tcctagcact cgggaggcag aggcaggcgg atttctgagt tcgaggccag cctggtctac
     1561 agagtgagtt ccaggacagc cagggctata cagagaaacc ctgtctcgaa aaaacaaaca
     1621 aaaaaaccaa aaaaaccaaa aacaaacaaa aaatagcctg tttatataaa tacaatcaaa
     1681 atggtagaat gtcaaaggtt ataactaact cttggtataa ttgttttcaa cccagtaaag
     1741 tgatttattg tgaaattgtc tccttatcaa cttactgtat ttctatttga tttttaaaaa
     1801 cacatatgag cactgattgg tttgttagaa actggagata aggtaaatgg ctatttcaag
     1861 tcaacagatc tgggtatttt taaagggcaa aagcagtcag tgtattctgg tagaaggctc
     1921 tcttagggtt agtaaatgga agaagtcaga tgtgcgtttc tagagttaag atcctgtttt
     1981 tgctaaagga aagaattaac tgagtacgtc agtatagact tagtttcctg ttctgtgcac
     2041 aagtgaagga ggagtaactg ggaaggagtc ggcagctctc cactctggaa gcaggattcg
     2101 gaaggattcc aatgcctcta tggatgaacg taaagagtgg taacacaaat attaaagacg
     2161 taagaaataa aagtcatagt tagaaaaacc tgtaccaaat ctgactttta ctgaaataaa
     2221 aattaagagt aatgttaact ctccaggagg agcaacttcc taagctgagc tcattctcag
     2281 ataaatacac aattttagct gtg
//
