LOCUS       NM_001085493            1083 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase complex assembly factor
            6 (Ndufaf6), mRNA.
ACCESSION   NM_001085493 XM_131300 XM_905831
VERSION     NM_001085493.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1083)
  AUTHORS   Zurkirchen,L., Varum,S., Giger,S., Klug,A., Hausel,J., Bossart,R.,
            Zemke,M., Cantu,C., Atak,Z.K., Zamboni,N., Basler,K. and Sommer,L.
  TITLE     Yin Yang 1 sustains biosynthetic demands during brain development
            in a stage-specific manner
  JOURNAL   Nat Commun 10 (1), 2192 (2019)
   PUBMED   31097699
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1083)
  AUTHORS   Varum,S., Baggiolini,A., Zurkirchen,L., Atak,Z.K., Cantu,C.,
            Marzorati,E., Bossart,R., Wouters,J., Hausel,J., Tuncer,E.,
            Zingg,D., Veen,D., John,N., Balz,M., Levesque,M.P., Basler,K.,
            Aerts,S., Zamboni,N., Dummer,R. and Sommer,L.
  TITLE     Yin Yang 1 Orchestrates a Metabolic Program Required for Both
            Neural Crest Development and Melanoma Formation
  JOURNAL   Cell Stem Cell 24 (4), 637-653 (2019)
   PUBMED   30951662
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732497.15.
            
            On Jan 26, 2013 this sequence version replaced NM_001085493.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009547.1, SRR7345562.2109584.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AL732497.15        170925-171150       c
            227-326             AL732497.15        168089-168188       c
            327-449             AL732497.15        165145-165267       c
            450-506             AL732497.15        161596-161652       c
            507-609             AL732497.15        156995-157097       c
            610-743             AL732497.15        155806-155939       c
            744-845             AL732497.15        153957-154058       c
            846-902             AL732497.15        148377-148433       c
            903-1083            AL732497.15        145990-146170       c
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 4.91 cM"
     gene            1..1083
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /note="NADH:ubiquinone oxidoreductase complex assembly
                     factor 6"
                     /db_xref="GeneID:76947"
                     /db_xref="MGI:MGI:1924197"
     exon            1..226
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..1031
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /note="UPF0551 protein C8orf38 homolog, mitochondrial;
                     NADH dehydrogenase (ubiquinone) complex I, assembly factor
                     6"
                     /codon_start=1
                     /product="NADH dehydrogenase (ubiquinone) complex I,
                     assembly factor 6 precursor"
                     /protein_id="NP_001078962.1"
                     /db_xref="CCDS:CCDS38691.1"
                     /db_xref="GeneID:76947"
                     /db_xref="MGI:MGI:1924197"
                     /translation="MATSMLGSVRGPRPFGLANLFHRQPPRDAWERVRRLPGPSAVRR
                     SVAAASGPGIPGSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQVKD
                     SVSEKTIGLMRMQFWKKAVEDMYCDNPPHQPVAIELWKAVKKHNLTKRWLMRIIDERE
                     KNLDDKAYRSMQELENYAENTQGSLLYLTLEVLGVKDLHADHAASHIGKAQGIVTCLR
                     ATPYHSSRRQVFLPMDVCVQHGVSQEDFLRRNQDKNVRDVVYDIASQAHLHLKHARSF
                     HRSVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNMLLPLSLYIQSWRKRY"
     exon            227..326
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            327..449
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            450..506
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            507..609
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            610..743
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            744..845
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            846..902
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1083
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1027..1032
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /note="hexamer: ACTAAA"
     polyA_site      1050
                     /gene="Ndufaf6"
                     /gene_synonym="2310030N02Rik"
                     /note="major polyA site"
ORIGIN      
        1 agggtcggag ggcacccgaa gcgggtgtca tggcgacctc catgctgggt tctgtccgcg
       61 gcccaaggcc attcggtttg gctaacctgt tccatcgcca gccgcctcgg gatgcgtggg
      121 aacgtgtgcg gcgcctgccg gggccctcgg cggtccggcg cagcgtggcg gcggccagcg
      181 ggccaggcat ccccggttcc cacctctact gcctggagct gctgaggaaa cgagattatg
      241 aaagctactt gtgttcctta ctgttccctg cagagtgtca aaggtctgct tctgcactgc
      301 gggccttcaa tgtggaactg gctcaggtta aggactcagt ctctgagaaa acaattggac
      361 tgatgcgcat gcagttctgg aaaaaagctg tggaagatat gtactgtgac aacccaccac
      421 accagccggt ggccattgaa ctctggaagg ctgtcaagaa acataaccta actaaaaggt
      481 ggctcatgag aatcattgat gaaagagaaa aaaatctgga tgacaaagcg taccgcagta
      541 tgcaggaact tgaaaattat gctgagaata cgcagggttc cctgctctac ctgacactgg
      601 aggtgctggg cgtgaaggat cttcatgcag atcatgctgc aagccacatt ggaaaggcac
      661 aaggcattgt cacgtgcttg agagcaacac cctatcacag tagcaggaga caggtgttcc
      721 tgcccatgga tgtctgtgtg cagcatggtg tttcacaaga ggactttcta cggaggaacc
      781 aagataaaaa tgtgagagat gtagtatatg acattgccag ccaggcccac ttgcacctaa
      841 agcatgcgag gtccttccac agaagcgtcc ctgcggaagc gtttcctgct tttcttcaga
      901 cggtttctct agaggactac ttaaagaaaa tccagcgagt agactttgat atattccatc
      961 cgtctttaca gcagaagaac atgttacttc cattatcttt gtatattcaa tcatggagaa
     1021 aaagatacta aaatgatttt atgttgctca tactgattta cttttagttt attggtttaa
     1081 aaa
//
