LOCUS       NM_026742               3632 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase complex assembly factor
            4 (Ndufaf4), mRNA.
ACCESSION   NM_026742
VERSION     NM_026742.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3632)
  AUTHORS   Schlehe,J.S., Journel,M.S., Taylor,K.P., Amodeo,K.D. and
            LaVoie,M.J.
  TITLE     The mitochondrial disease associated protein Ndufaf2 is dispensable
            for Complex-1 assembly but critical for the regulation of oxidative
            stress
  JOURNAL   Neurobiol Dis 58, 57-67 (2013)
   PUBMED   23702311
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY163651.1, AK160341.1 and AL772223.7.
            
            On May 9, 2009 this sequence version replaced NM_026742.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034728.1, SRR7652917.969821.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 BY163651.1         6-10
            6-988               AK160341.1         2-984
            989-3632            AL772223.7         123345-125988
FEATURES             Location/Qualifiers
     source          1..3632
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 10.52 cM"
     gene            1..3632
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /note="NADH:ubiquinone oxidoreductase complex assembly
                     factor 4"
                     /db_xref="GeneID:68493"
                     /db_xref="MGI:MGI:1915743"
     exon            1..220
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..606
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /note="hormone-regulated proliferation-associated protein
                     of 20 kDa homolog; NADH dehydrogenase (ubiquinone) 1 alpha
                     subcomplex, assembly factor 4"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 alpha
                     subcomplex assembly factor 4"
                     /protein_id="NP_081018.1"
                     /db_xref="CCDS:CCDS18007.1"
                     /db_xref="GeneID:68493"
                     /db_xref="MGI:MGI:1915743"
                     /translation="MGARVTRALRNFNVEKRAEREISKRKPSMAPKHPSTRDLLQEHR
                     SQYPEIEEVVSKKDNKLLSLLRDVYVDSKDPVPALPVKVEPRQEPKEFRLPIGNHFDK
                     NITDIPKGKITVVEALTLLNNHKLSPETWTAEKIAQEYYLELKDVNSLLKYFVTFEVK
                     ILPPEDRKAIQSK"
     exon            221..324
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            325..3632
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      825..830
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      848
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /note="major polyA site"
     regulatory      2105..2110
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2131
                     /gene="Ndufaf4"
                     /gene_synonym="1110007M04Rik; 3000003G13Rik"
                     /note="major polyA site"
ORIGIN      
        1 tgcgcatgct ccgtgcgtac agaggtcacc ggtgccggtg gcttctacac gtgcgtagtg
       61 aactaagggc atcatgattt agagatgggg gctcgcgtga cccgcgcctt aaggaacttc
      121 aacgtggaga agcgagcgga gcgagagatc agcaagagga agccctccat ggcacccaag
      181 cacccttcta cccgcgacct cctgcaggag caccggagtc agtatccaga aatcgaagaa
      241 gttgtttcta aaaaagataa caagctgctg tcattgctaa gagatgtata tgtcgattcc
      301 aaagatccgg tgcctgcctt gccggtaaaa gttgaaccac gacaagaacc aaaggaattc
      361 agactgccga taggaaatca ctttgataag aatatcacgg acattcccaa aggcaagatt
      421 actgttgtag aggcattgac ccttctcaat aaccataaac tctctccaga aacatggact
      481 gctgagaaaa tcgctcaaga gtactattta gaactgaagg atgtaaattc ccttctcaaa
      541 tattttgtta cttttgaagt caaaatctta cctccagaag acaggaaagc aatacaatca
      601 aaatgaagaa aatcacgaaa caacttcccc tgtatgtgtt cccaagctcc gcgcccttgt
      661 tttgcgtgta ttaaattata caagttcctg tgagttgagg gccataacgt ttgaaagctc
      721 tttgacctcc tcaggattgt tcatataatt ttttaaaaat ttatgtatgt gtagttcctg
      781 ggtatatgtt agctgtattg atcatgtggc ccaaatgagt caatattaaa ttccactttc
      841 tagtttaagt tggtttgttc tttgtagtag acactgaaag caagagtcct cctgactcct
      901 ataagactgg cattgtgtta gggacagata atcagcaggg aaacacagtg actatatttc
      961 ccaagtgaag aaagagagaa aactgagtga aaagaaagaa aaatacatat tactactcta
     1021 gagatgaaaa atccatgagg atctttttaa tgttttaaat ttgttttaaa tattaaataa
     1081 ttttatagaa gaattagtgg tatctgacat gctggctgtc tctcttttga caaatagaaa
     1141 taggtaactt gaaaaggttt ctaagagcga ggcaatactt aaagattatt tgaacaaata
     1201 gcttctttaa tttagaagtg agagaagtat gaaagaacag ctaaaaataa gagaatccaa
     1261 tttgataacc aaacattcat acctgttttt attttaggag gaaaaataac cagtagaagt
     1321 atagaataaa tccctgaagg gacctagaaa gttaccaatt cattcactta agctctggaa
     1381 tgttacattc cagtaataga atctcagata aggtgagatg agtttggctc attctggcat
     1441 gttatacttg tgggttcttg cccatattgt ttgacctctc tgaaattgaa tttctataaa
     1501 agtatacctg ccttatataa attccaggac aacaatgaag ataaatgaca aaagaccagg
     1561 caaatacaaa gtcttgtagt taaaatgggt gtctacaaaa cacacaacag agttacctgt
     1621 agtttatgat gcaaggaagc cagaatttag gttctcgaaa tcctagtagt atttttactt
     1681 attctgtaaa atgaaataca tttcaaaagg acagaatgga gttggggtaa ctgggctcgt
     1741 ccatattctt tcacgggaac agacagacat acttgcctcg agattccacg ggaaaagatg
     1801 tggaagatga gaagaatcca gcgatgatgg agggaggcag atggaacagc aaagatggga
     1861 ggtgactgga gagtttgtca gcttcttcat atctagttcc agtgaagaaa ctatccctac
     1921 ttatatgtga ttcaatacag aagtttaagg gaacctacta attccaatca ttgctgatta
     1981 tggtggaaag tgccgtcaaa accatcctcc attaattcaa aatgaatatg tgaatcagca
     2041 gtactgactc aggtttcctg ggtggctagc agatgtaaat atggtttctt aactggtatc
     2101 acacaataaa atccttccat tttgcacatt agcccacttt tctggttttt tctttcatgt
     2161 agaacaccaa ttgtaacgtc acacaaggtg catgaaattt acatttggaa aagcggagtt
     2221 tagatgtcgg ttccttaact agctgtgtct gacttgtcta caactaaagt gcagtttata
     2281 tactggacac taacctaggt gccttacatg tcttagcttt gttagcattg tggtaacaag
     2341 cgtgaagtta agaatgcttt cctgggaaag ttgcagcccg ggaaacttca gtaactacaa
     2401 agattagtgg atactgaaga gtaaatagaa tattttgtac tgactactac actggattgc
     2461 ctgtatggga gttgtaagaa ttatgtgaat tgatacacgg gttacctgag cacaaagggc
     2521 caaaacttct caaatgtctg cttctgtaag tcctttgtag agctctgggc taatagatga
     2581 ctaaacgctc tctgctatga gagactggat agcaagatta aaatccctga ataaatggat
     2641 tctagatcaa agatgctcta aaactgacca gtgactggta ttggggtctc acatttattt
     2701 tgaaaagtga ggaatgggaa actgaatttg aaggaatgga attgaataag gaggagagga
     2761 gaaaaaaact agatttggct tttgtaaaaa tgagagctga gagagctgtt catgaagaag
     2821 cctgcagcag aagagtgggt ggtttgggta aagttctact ctaaagagat aggctatcca
     2881 aacttaggca taccagcaaa accaaccact tagtgtcaag acacacatag atacactcag
     2941 gtaagctcac ccaaccacaa agactgtctc aaagccattt gatataacat cttagcttta
     3001 ccttttactt ttggagtggg ttggtgtttg aggtaatatc ttactgtgta ggccaagctg
     3061 tcctcaaact ctttaaccca gctgcagcac ccctcccccc ccatccccca gtgctgtcct
     3121 tagctccagt atgttatcat ttagtgcctc atcactctga aagagctgtg tgtttgctca
     3181 ggaatgaaca tccttctttc catatttact cagtgcactt aaacactcat gatctttgat
     3241 ctgaatctct atatgataaa tagctattta atacagagct ttttagtgat taattccaga
     3301 gaccctgtct cccccaatgg ttagttactg ggtagtgtta acaataaagc tagtcatggg
     3361 ttcagcctga tcatcttcat tcacagttgc cataactgcc cagaataaca ctgcttttca
     3421 ttgcaatgat tggcttttat tggtagaatt ggaatgtgtc tgtctgatat aagcttgaga
     3481 taacccaggt acattctggt ttggatgaag tcatttttgc tctgactact ttataaacta
     3541 ctgtcattct aacttatggg aattcaccaa ctcctgatgt catccaggac tgcttttgtc
     3601 aatcagtccc caataaactg cactgcaatc ct
//
