LOCUS       NM_025987                504 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit A6 (Ndufa6),
            mRNA.
ACCESSION   NM_025987
VERSION     NM_025987.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 504)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 504)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 504)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 504)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 504)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104325.28.
            
            On Jan 23, 2023 this sequence version replaced NM_025987.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU562908.1, BU524958.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AC104325.28        202997-203153       c
            158-273             AC104325.28        199895-200010       c
            274-504             AC104325.28        199057-199287       c
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.56 cM"
     gene            1..504
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /note="NADH:ubiquinone oxidoreductase subunit A6"
                     /db_xref="GeneID:67130"
                     /db_xref="MGI:MGI:1914380"
     exon            1..157
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..405
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /note="CI-B14; complex I-B14; NADH-ubiquinone
                     oxidoreductase B14 subunit; NADH dehydrogenase
                     (ubiquinone) 1 alpha subcomplex, 6 (B14)"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 alpha
                     subcomplex subunit 6"
                     /protein_id="NP_080263.1"
                     /db_xref="CCDS:CCDS27689.1"
                     /db_xref="GeneID:67130"
                     /db_xref="MGI:MGI:1914380"
                     /translation="MAAAATGLRQAAAAAASTSVKPIFSRDLNEAKRRVRELYRAWYR
                     EVPNTVHLMQLDITVKQGRDKVREMFMKNAHVTDPRVVDLLVIKGKMELQETIKVWKQ
                     RTHVMRFFHETETPRPKDFLSKFYMGHDP"
     exon            158..273
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            274..504
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      451..456
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /note="hexamer: AATAAA"
     regulatory      480..485
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /note="hexamer: GATAAA"
     polyA_site      486
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
                     /note="major polyA site"
     polyA_site      504
                     /gene="Ndufa6"
                     /gene_synonym="14kDa; 2700038D15Rik; B230217P19Rik"
ORIGIN      
        1 ctcggcaaga tggcggccgc ggccaccggc ctgcgccaag ctgctgctgc ggcagccagt
       61 acctcggtga agcccatttt cagtcgcgac ctgaacgagg ccaagcggag ggtgcgcgag
      121 ctctaccgcg cttggtatcg ggaggtgccg aacaccgtgc acttaatgca gctggatatc
      181 acggtgaaac aaggacggga taaagtccga gaaatgttca tgaagaatgc ccatgtcaca
      241 gaccccagag tggttgatct gctggtcatt aagggaaaga tggagctcca ggaaaccatc
      301 aaagtatgga agcagcggac acacgttatg cggtttttcc atgaaacaga aacaccaagg
      361 ccaaaggatt tcttatctaa gttctatatg ggccatgacc catgaggtca cctgatggga
      421 aggtgcatgt taatatttaa ctagagtata aataaactca ttatttgatg gttggttgtg
      481 ataaaattgc actggtgaac ccct
//
