LOCUS       NM_024197               1222 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit A10 (Ndufa10),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_024197
VERSION     NM_024197.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 1222)
  AUTHORS   Guo,P., Hu,S., Liu,X., He,M., Li,J., Ma,T., Huang,M., Fang,Q. and
            Wang,Y.
  TITLE     CAV3 alleviates diabetic cardiomyopathy via inhibiting
            NDUFA10-mediated mitochondrial dysfunction
  JOURNAL   J Transl Med 22 (1), 390 (2024)
   PUBMED   38671439
  REMARK    GeneRIF: CAV3 alleviates diabetic cardiomyopathy via inhibiting
            NDUFA10-mediated mitochondrial dysfunction.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1222)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 1222)
  AUTHORS   Chong,D., Gu,Y., Zhang,T., Xu,Y., Bu,D., Chen,Z., Xu,N., Li,L.,
            Zhu,X., Wang,H., Li,Y., Zheng,F., Wang,D., Li,P., Xu,L., Hu,Z. and
            Li,C.
  TITLE     Neonatal ketone body elevation regulates postnatal heart
            development by promoting cardiomyocyte mitochondrial maturation and
            metabolic reprogramming
  JOURNAL   Cell Discov 8 (1), 106 (2022)
   PUBMED   36220812
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1222)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1222)
  AUTHORS   Wirtz,S. and Schuelke,M.
  TITLE     Region-specific expression of mitochondrial complex I genes during
            murine brain development
  JOURNAL   PLoS One 6 (4), e18897 (2011)
   PUBMED   21556144
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1222)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   8  (bases 1 to 1222)
  AUTHORS   Cui,X.S., Li,X.Y., Shen,X.H., Bae,Y.J., Kang,J.J. and Kim,N.H.
  TITLE     Transcription profile in mouse four-cell, morula, and blastocyst:
            Genes implicated in compaction and blastocoel formation
  JOURNAL   Mol Reprod Dev 74 (2), 133-143 (2007)
   PUBMED   16998848
  REMARK    Review article
REFERENCE   9  (bases 1 to 1222)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   10 (bases 1 to 1222)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC003439.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003439.1, AK013675.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 46.4 cM"
     gene            1..1222
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /note="NADH:ubiquinone oxidoreductase subunit A10"
                     /db_xref="GeneID:67273"
                     /db_xref="MGI:MGI:1914523"
     exon            1..96
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..1089
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
                     subunit 10, mitochondrial; CI-42kD; complex I-42kD;
                     NADH-ubiquinone oxidoreductase 42 kDa subunit; NADH
                     dehydrogenase (ubiquinone) 1 alpha subcomplex 10"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 alpha
                     subcomplex subunit 10, mitochondrial precursor"
                     /protein_id="NP_077159.1"
                     /db_xref="CCDS:CCDS15167.1"
                     /db_xref="GeneID:67273"
                     /db_xref="MGI:MGI:1914523"
                     /translation="MALRLLRLVPASAPARGLAAGAQRVGRIHTSVHCKLRYGLLAAI
                     LGDKTTKKLHEYSRVITVDGNICSGKNKLAKEIAQQLGMKHYPEAGIQYSSTTTGDGR
                     PLDIEFSGSCSLEKFYDDPKSNDGNSYRLQSWLYASRLLQYADALEHLLSTGQGVVLE
                     RSIYSDFVFLEAMYNQGYIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVPEVQSRI
                     QKKGDPHEMKVTSAYLQDIENAYKKTFLPKMSEMCEVLVYDSWEAEDPTKVVEDIEYL
                     KYNKGPWLKQDDWTFHYLRMLVQDKTEVLNYTTIPVYLPEITIGAHQGSRIYNSFREL
                     PGRKYAPGYNAEVGDKWIWLK"
     exon            97..265
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            266..481
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            482..568
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            569..690
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            691..770
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            771..825
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            826..911
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1020
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1220
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1175
                     /gene="Ndufa10"
                     /gene_synonym="2900053E13Rik"
                     /note="major polyA site"
ORIGIN      
        1 gccggcgcag acggcgaagt catggccttg aggttgctga gactcgtccc ggcgtcggct
       61 cccgcgcgcg gcctcgcggc cggagcccag cgcgtgggac gaattcatac cagtgtgcac
      121 tgcaagctga ggtatgggct tttggccgcc attcttggtg ataagacaac caaaaagctg
      181 catgagtaca gccgagtgat aacagtagat gggaacatat gctctgggaa aaacaagctc
      241 gcaaaggaga tcgcacagca actaggcatg aagcactacc cagaagcagg gatacagtac
      301 tcaagcacca ccacaggcga tggaaggccc ctcgacatag agtttagtgg cagctgtagt
      361 ttagagaaat tttatgatga tcccaagagc aacgatggca acagctaccg cctgcagtcc
      421 tggctgtatg ccagccgcct tcttcagtat gcagatgccc tggagcacct gctgagcaca
      481 ggacaaggtg tggtcttgga gcgctccatc tacagtgact ttgtcttcct ggaggcaatg
      541 tacaaccagg gctatatccg aaagcagtgt gtggaccact ataatgaaat taagcggctc
      601 actctcccgg agtacctgcc accacacgca gtcatctata tcgatgtgcc cgtgccggag
      661 gtacagagca ggatccagaa gaaaggagat ccacatgaaa tgaaggtcac ctctgcctat
      721 ctccaggaca tcgagaatgc gtacaagaaa accttcctcc ccaaaatgag tgaaatgtgt
      781 gaggtgttgg tgtacgattc ctgggaagct gaagacccaa ccaaggtggt agaggacatt
      841 gaatacctta agtacaacaa agggccttgg ctgaaacagg acgactggac ctttcactac
      901 ctgcggatgc tggttcagga taagacagaa gtgctgaatt acacgaccat tccggtctac
      961 ctcccagaaa tcactattgg agctcatcag ggtagccgga tctacaacag cttcagagag
     1021 ctgccaggcc gcaagtatgc ccctgggtac aatgccgagg tgggtgacaa gtggatctgg
     1081 ctgaagtgaa gggtcccctc cgcccagccg tgtcatagcc atggagatgc ctgctctgcc
     1141 caactctgtg aactccagag ctttccaaga caacaggaaa aaaagcaaat gatcaagaaa
     1201 ttgccagaaa aaaaaaaaaa aa
//
