LOCUS       NM_019443                516 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus NADH:ubiquinone oxidoreductase subunit A1 (Ndufa1),
            mRNA.
ACCESSION   NM_019443
VERSION     NM_019443.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Wu,Y., Chen,S., Huang,G., Zhang,L., Zhong,L., Feng,Y., Wen,P. and
            Liu,J.
  TITLE     Transcriptome analysis reveals EBF1 ablation-induced injuries in
            cardiac system
  JOURNAL   Theranostics 14 (12), 4894-4915 (2024)
   PUBMED   39239522
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   3  (bases 1 to 516)
  AUTHORS   Beutner,G., Burris,J.R., Collins,M.P., Kulkarni,C.A.,
            Nadtochiy,S.M., de Mesy Bentley,K.L., Cohen,E.D., Brookes,P.S. and
            Porter,G.A. Jr.
  TITLE     Coordinated metabolic responses to cyclophilin D deletion in the
            developing heart
  JOURNAL   iScience 27 (3), 109157 (2024)
   PUBMED   38414851
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 516)
  AUTHORS   Ishikawa,K. and Nakada,K.
  TITLE     Attempts to understand the mechanisms of mitochondrial diseases:
            The reverse genetics of mouse models for mitochondrial disease
  JOURNAL   Biochim Biophys Acta Gen Subj 1865 (3), 129835 (2021)
   PUBMED   33358867
  REMARK    Review article
REFERENCE   5  (bases 1 to 516)
  AUTHORS   Signes,A. and Fernandez-Vizarra,E.
  TITLE     Assembly of mammalian oxidative phosphorylation complexes I-V and
            supercomplexes
  JOURNAL   Essays Biochem 62 (3), 255-270 (2018)
   PUBMED   30030361
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 516)
  AUTHORS   Oda,M., Yamagiwa,A., Yamamoto,S., Nakayama,T., Tsumura,A.,
            Sasaki,H., Nakao,K., Li,E. and Okano,M.
  TITLE     DNA methylation regulates long-range gene silencing of an X-linked
            homeobox gene cluster in a lineage-specific manner
  JOURNAL   Genes Dev 20 (24), 3382-3394 (2006)
   PUBMED   17182866
REFERENCE   7  (bases 1 to 516)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   8  (bases 1 to 516)
  AUTHORS   Yadava,N., Potluri,P., Smith,E.N., Bisevac,A. and Scheffler,I.E.
  TITLE     Species-specific and mutant MWFE proteins. Their effect on the
            assembly of a functional mammalian mitochondrial complex I
  JOURNAL   J Biol Chem 277 (24), 21221-21230 (2002)
   PUBMED   11937507
  REMARK    GeneRIF: Species-specific and mutant MWFE proteins effect on the
            assembly of a functional mammalian mitochondrial complex I.
REFERENCE   9  (bases 1 to 516)
  AUTHORS   Gaikwad,J.S., Cavender,A. and D'Souza,R.N.
  TITLE     Identification of tooth-specific downstream targets of Runx2
  JOURNAL   Gene 279 (1), 91-97 (2001)
   PUBMED   11722849
REFERENCE   10 (bases 1 to 516)
  AUTHORS   Frattini,A., Faranda,S., Bagnasco,L., Patrosso,C., Nulli,P.,
            Zucchi,I. and Vezzoni,P.
  TITLE     Identification of a new member (ZNF183) of the Ring finger gene
            family in Xq24-25
  JOURNAL   Gene 192 (2), 291-298 (1997)
   PUBMED   9224902
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI844651.1, AK007840.1 and CF383819.1.
            
            On Jul 19, 2006 this sequence version replaced NM_019443.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AI844651.1, BU554753.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                AI844651.1         405-499             c
            96-491              AK007840.1         3-398
            492-516             CF383819.1         276-300
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 21.61 cM"
     gene            1..516
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /note="NADH:ubiquinone oxidoreductase subunit A1"
                     /db_xref="GeneID:54405"
                     /db_xref="MGI:MGI:1929511"
     exon            1..250
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /inference="alignment:Splign:2.1.0"
     CDS             149..361
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /EC_number="1.6.99.3"
                     /note="NADH ubiquinone oxidoreductase subunit MWFE; NADH
                     dehydrogenase 1 alpha subcomplex, 1; CI-MWFE; complex
                     I-MWFE; NADH-ubiquinone oxidoreductase MWFE subunit; NADH
                     dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD,
                     MWFE)"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 alpha
                     subcomplex subunit 1"
                     /protein_id="NP_062316.1"
                     /db_xref="CCDS:CCDS40928.1"
                     /db_xref="GeneID:54405"
                     /db_xref="MGI:MGI:1929511"
                     /translation="MWFEILPGLAIMGVCLVIPGVSTAYIHKFTNGGKEKRVARVQYQ
                     WYLMERDRRISGVNRYYVSKGLENID"
     exon            251..340
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /inference="alignment:Splign:2.1.0"
     exon            341..494
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      470..475
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /note="hexamer: AATAAA"
     polyA_site      494
                     /gene="Ndufa1"
                     /gene_synonym="1810049F12Rik; MWFE"
                     /note="major polyA site"
ORIGIN      
        1 gtcacttttg ggcccccaca gccaccgtcg cttcctcctc cggagccgta cggggcaccg
       61 cccctcccgc gtgctgccgg aagagaggta aagccgggtc acctctgagg agccggtgac
      121 gggttggcgt gcgagtaacg gtgcggagat gtggttcgag attctccctg gcctcgccat
      181 tatgggggtg tgcttggtca tccccggggt gtccactgcg tacatccaca aattcaccaa
      241 cgggggcaag gaaaaacgag ttgctcgtgt tcagtaccag tggtatctga tggaacgcga
      301 tagacgtatc tctggagtca atcgctacta tgtgtccaag ggcctggaaa acattgacta
      361 aggaagcatt ttcctggctg attaaaagaa attactcagc tatggtcatc tgttcctgtt
      421 agaaggctat gcagcatatt atatactatg cgcatgttat gaaatgcata ataaaaaatt
      481 ttaaaaaatc taaaaaaaaa aaaaaaaaaa aaaaaa
//
