LOCUS       NM_172495               5353 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus nuclear receptor coactivator 7 (Ncoa7), transcript
            variant 1, mRNA.
ACCESSION   NM_172495
VERSION     NM_172495.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5353)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5353)
  AUTHORS   Guo,J., Ke,S., Chen,Q., Zhou,J., Guo,J. and Qiu,T.
  TITLE     NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell
            Carcinoma via MAPK/ERK Signaling Pathway
  JOURNAL   Int J Mol Sci 24 (14), 11584 (2023)
   PUBMED   37511343
  REMARK    GeneRIF: NCOA7 Regulates Growth and Metastasis of Clear Cell Renal
            Cell Carcinoma via MAPK/ERK Signaling Pathway.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5353)
  AUTHORS   Castroflorio,E., den Hoed,J., Svistunova,D., Finelli,M.J.,
            Cebrian-Serrano,A., Corrochano,S., Bassett,A.R., Davies,B. and
            Oliver,P.L.
  TITLE     The Ncoa7 locus regulates V-ATPase formation and function,
            neurodevelopment and behaviour
  JOURNAL   Cell Mol Life Sci 78 (7), 3503-3524 (2021)
   PUBMED   33340069
  REMARK    GeneRIF: The Ncoa7 locus regulates V-ATPase formation and function,
            neurodevelopment and behaviour.
REFERENCE   4  (bases 1 to 5353)
  AUTHORS   Ihara,D., Watanabe,Y., Seya,D., Arai,Y., Isomoto,Y., Nakano,A.,
            Kubo,A., Ogura,T., Kawamura,T. and Nakagawa,O.
  TITLE     Expression of Hey2 transcription factor in the early embryonic
            ventricles is controlled through a distal enhancer by Tbx20 and
            Gata transcription factors
  JOURNAL   Dev Biol 461 (2), 124-131 (2020)
   PUBMED   32035085
REFERENCE   5  (bases 1 to 5353)
  AUTHORS   Gargaro,M., Vacca,C., Massari,S., Scalisi,G., Manni,G.,
            Mondanelli,G., Mazza,E.M.C., Bicciato,S., Pallotta,M.T.,
            Orabona,C., Belladonna,M.L., Volpi,C., Bianchi,R., Matino,D.,
            Iacono,A., Panfili,E., Proietti,E., Iamandii,I.M., Cecchetti,V.,
            Puccetti,P., Tabarrini,O., Fallarino,F. and Grohmann,U.
  TITLE     Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid
            Enhances Activation of Aryl Hydrocarbon Receptor in
            Immunoregulatory Dendritic Cells
  JOURNAL   Front Immunol 10, 1973 (2019)
   PUBMED   31481962
  REMARK    GeneRIF: Engagement of Nuclear Coactivator 7 by
            3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon
            Receptor in Immunoregulatory Dendritic Cells.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5353)
  AUTHORS   Finelli,M.J., Sanchez-Pulido,L., Liu,K.X., Davies,K.E. and
            Oliver,P.L.
  TITLE     The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif
            (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against
            Oxidative Stress
  JOURNAL   J Biol Chem 291 (6), 2751-2763 (2016)
   PUBMED   26668325
REFERENCE   7  (bases 1 to 5353)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   8  (bases 1 to 5353)
  AUTHORS   Paramanik,V. and Thakur,M.K.
  TITLE     Interaction of Estrogen Receptor Associated Protein (ERAP) 140 with
            ER beta decreases but its expression increases in aging mouse
            cerebral cortex
  JOURNAL   Cell Mol Neurobiol 30 (6), 961-966 (2010)
   PUBMED   20446107
  REMARK    GeneRIF: ERAP 140 interacts with ER beta and its interaction
            decreases but its expression increases with age in mouse cerebral
            cortex.
REFERENCE   9  (bases 1 to 5353)
  AUTHORS   Shkolnik,K., Ben-Dor,S., Galiani,D., Hourvitz,A. and Dekel,N.
  TITLE     Molecular characterization and bioinformatics analysis of Ncoa7B, a
            novel ovulation-associated and reproduction system-specific Ncoa7
            isoform
  JOURNAL   Reproduction 135 (3), 321-333 (2008)
   PUBMED   18299425
REFERENCE   10 (bases 1 to 5353)
  AUTHORS   Shao,W., Halachmi,S. and Brown,M.
  TITLE     ERAP140, a conserved tissue-specific nuclear receptor coactivator
  JOURNAL   Mol Cell Biol 22 (10), 3358-3372 (2002)
   PUBMED   11971969
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125532.3, BB870337.1, BC076623.1 and BC080742.1.
            
            On Dec 12, 2017 this sequence version replaced NM_172495.5.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and it encodes the longest protein (isoform 1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164140
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-388               AC125532.3         74511-74898
            389-729             BB870337.1         2-342
            730-5320            BC076623.1         117-4707
            5321-5353           BC080742.1         3857-3889
FEATURES             Location/Qualifiers
     source          1..5353
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 17.11 cM"
     gene            1..5353
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /note="nuclear receptor coactivator 7"
                     /db_xref="GeneID:211329"
                     /db_xref="MGI:MGI:2444847"
     exon            1..498
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            499..619
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            620..840
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            841..920
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1028
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1142
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1268
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1453
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..2484
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2485..2653
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..2801
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2802..2933
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2934..3086
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3087..3182
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3183..3256
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3257..5326
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5298..5303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5326
                     /gene="Ncoa7"
                     /gene_synonym="9030406N13Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggctgtccag cctgcggctc cgaggtcgca cggggcaggc aagatgtcgc agctgcagcc
       61 cgcatcgcta aggcggtcgg ctgagctccc gggtcccagc cgcagcagac gagtgcagcg
      121 cgcgccccgg gtcgggcgga gctagaggcg ggcgccgggc tggcgtcgcg ccaccgcagc
      181 tccccgcctt ccgcccagct cgcgcccggc gccctgaccg tgggtgctgc tgcaggtacc
      241 tgggcgaggc ctcgagcacc ccggcggcgg ctgctcgggc cagatcggca ctccggagcc
      301 cttcaggagc gcaccccgca gcgcctgacg cctcccttag ctcctcctcg gcgggcgatc
      361 ccctccccgg ccctccccct cctcccaccc cggaggatgc gcttcccagc gcccagcggc
      421 agaggccacg gctcccagaa atgcgtgctc ccgaaccact tcgcccagac ccgcggagcc
      481 cgcgcccccg cccagtagga atatgactca ctgattaaag aggacgtttc caaatacttt
      541 ttcactttta gctgtgtatt atggatacta aggaagagaa gaaggaacag aaggaacgga
      601 aacagagtta ttttgctaga ctaaaaaaga aaaaacaagc caaacaaaat gcagagatag
      661 tttcagctgc gtcctcgaag agtcgttccg ggaaagatga tgctaattca gacattttgg
      721 aacaagacaa gttcaacgtt acagcagagg gggaccatag cactgatgac aaaaagaaga
      781 gaaaaagtaa ccagttaaag gaaatcaggc gcacggaact gaagagatac tacagtgttg
      841 atgacaatca aaacaaaact catgataaaa aagagaagaa gatgatggtc caaaagccac
      901 agggcaccat ggaatacact gctggaagcc aggacaccct caactctgtt gcactgaagt
      961 ttaacgtcac tcccaataaa ttagtggaat tgaataaact cttcacacac actattgttc
     1021 caggccaggt cctgtttgtg ccagatgcca acatctcttc tagtaccata cagctttctt
     1081 catccacccc tggtgctact gtctctccat catcatcaga tgcagagtat gataagctgc
     1141 ctgatgcaga tttagcaaga aaggccttaa aacccatcga gagggtctta tcatctactt
     1201 ccgaagaaga tgagccaggt gttgtaaaat tcctcaaaat gaactgtcgc tacttcactg
     1261 atggaaaggg tgtggttggg ggtgtcatga ttgtcactcc taacaacatc atgtttgacc
     1321 ctcataagtc cgatccctta gtgattgaaa acggttgcga agaatatggt ctcatctgcc
     1381 ccatggaaga ggtggtctcc attgccctgt acagtgacat atcccacatg aagatcaaag
     1441 acgccttgcc atctgaccta cctcgggatc tttgtcctct gtacaggcct ggagaatggg
     1501 aggacctggc ttcagagaaa gatatcaatc cattcagtaa attcaagtcc atcaacaagg
     1561 aaaaacgaca gcagaatggg gagaggaccc ttgctttaga tgccaaatca gtgcgctctc
     1621 ctgaggagtc aactgaacgt acttgcacac gcatagagcc cccagacaac tctgaattgt
     1681 ggaaattaaa gaatctgcaa tcttccaggg gaacaaccag tgagtctccc tcagtgaccc
     1741 agctcagcat gcgtgctgcc ttggaaccta cagccaaaga aaactgtctt ttaaaaggag
     1801 atgaggactt tgttgacttg gaagaacttt cttctcaacc tgagagtgga atcaacaaag
     1861 gagatgccac gaaagaatgt ctttcctatg accaaaagaa ggatgggccg catacagtca
     1921 tgtctgcaaa gaaggggcac gtgcagtcag cccaggaagt tatgggacca gagagtgata
     1981 ctgaactgaa gggagcccta gatctagaaa ctgctgagaa gcaagatgaa gccccagaag
     2041 tagacaaaca ctctggatcc ccagaaaact tgggggaaag cacgctgaat atacacgaag
     2101 atctagataa aattaaactc attgaatttt acctaaataa aaacaaggaa gggtcacagc
     2161 tgttagaaaa tgtgcagaag tcagagttaa gtgaccgcaa aagtattgaa ccaggaggaa
     2221 tagacatcac acttagtagc tctcttcccc aagcaggtga ttccccacct gaggacaaca
     2281 aagagccagg tacactctgg gtaaaagggg gagaaactct gcccctgaaa ctagatccta
     2341 gtgcagagga aactgtaatt aacaataaag aggttctgga ttctttggga tcatctctag
     2401 acaagatgtg tcacagtgca cagatggata acaaatctga gattcagtta tggctgttaa
     2461 agagaattca ggtaccaatt gaagatatac ttccctcaaa agaagagaag agtaagaccc
     2521 cgcccatgtt tctgtgcatc aaagtgggaa agccaatgag aaaatccttt gccagtcaca
     2581 ccgccaccat ggttcagcag tatagcaaga gaagaaagca gcctgaatac tggtttgctg
     2641 ttccccggga gagggtggat cacttgtaca ccttctttgt tcagtggtct cctgatgtct
     2701 atgggaaaga tgccaaggag caaggctttg tggtggtgga gaaggaagag ctgaacatga
     2761 tcgacaattt cttcagtgag ccgaccacca agagctggga gatcatcaca gttgaggagg
     2821 caaaacgcag gaagagcact tgcagctact acgaggaaga ggaagaagag gaagagggac
     2881 tgcctatcct acagccccac agtgcactcc tggaaaacat gcacatcgaa cagctggccc
     2941 gacgacttcc agccagggta caaggctatc catggagact ggcctacagc acattagagc
     3001 atggaacgag cttgaagact ctctacagga aatcagcatc tctagatagt cctgttcttt
     3061 tggtcatcaa agacatggat aaccagatat ttggggcata tgcaactcat cccttcaagt
     3121 tcagtgacca ctattatggc acaggcgaaa cgtttctcta cacctttagt ccgaatttca
     3181 aggtctttaa gtggagtgga gaaaactcat attttatcaa tggagacata agttctttag
     3241 aacttggtgg tggaggggga cgatttggtc tgtggctaga tgctgattta tatcatggac
     3301 gcagcaactc ttgcagtact tttaataatg atatcctttc aaaaaaagaa gacttcatag
     3361 ttcaggacct agaggtatgg acatttgagt gaaactcagg ctgccttaaa ataaaacatg
     3421 gaaaagactg ggttagatta gccgtcttac tggaagacga gccccagccc tggctgcctc
     3481 atcctacagc aatgctttct tcctgcggtt gtctcagagc atcatagcaa tgcagacaga
     3541 ttctggaagg tactgtggag ggcagacact gaagacagaa atctcaagtc caggttgttt
     3601 taaaaaaaca aaacaaaaag actttgtacc tccactgctt tcaaattcac accatgagaa
     3661 atcagagtgt tttttgatgt atgagttgaa tgcaattttt atttttggta actgtgaaaa
     3721 aatatgatac tgtggaaata cataccttcc ttgtgtattt atcagcataa ttttaccaaa
     3781 tatatacttt ttgtttgcca tagaaagcta aatctgattt agagaaattg aaaggatata
     3841 gcacttaaag ggaatatctg attttttaaa aacttttatt tattattttt agtatattgt
     3901 ctgaaatata ttgatttttt tcttttaatg tgtcaaatcc tgaaataaag aaatgtatat
     3961 gttttgtgct attgggaaac aaggctcttt tgatttgtat agttttttat tcattttttg
     4021 ccctgattat ttagggtaat ataatcttta tttattaaga gagtgagaga gagggagaga
     4081 gagagagaga gagagtcaaa aagacagaga cagagttttc aaaagctcat taccaatgtt
     4141 ttttgatcta ttatagacca actttttatt tagtttttaa ggtaatcttt gaaaacccta
     4201 agcatttgtg tgaagcagaa tatagcttct ctcacagttg taagatggtg tttattgaaa
     4261 tacagatctt tatgaacatg aatgtacaag tcctacttct acagagtgtt tgtttcttat
     4321 gaaattgtgt gaattgtata ttaataacag taactaagtt tcttagtttt ttttcttttt
     4381 ttcattcctt ttcttttttt tcttttacgt tgtttctttc caggtgttta cattaatggt
     4441 agccatctgt tttaaaagag agtatataat ttgtgcattt ttaatgttgg ataaaagatg
     4501 ccaagttgga ccaactttct tggtttcttg aatcttactg gagaaaaaac aattcaaaga
     4561 attacattca tatcacaatt gaaagaaaaa agaaaatcta tattttttta aatataaact
     4621 cattttcaca tcagtagaca tcttttattt taaatagtag gatataaaat cattaatgtt
     4681 aatgattgcc tccctcttat gaaagccaaa gactactaat ggaaaaaatt taaataatag
     4741 ccaaagctga aaagtagtct atcgcgaatt atttccccag agatttttga acagaaaatg
     4801 agcaaaccgt gtttacatgt ctgtttatgt ttgtcatatt ttcaagtctt tcttccattt
     4861 tagcctcctt gtaagaaaac actgtccagt ggtctccatc aggccgatca ctatattcac
     4921 tgccatccca tgctagttta aaggaatgct atgaaaattt aaatctgtag accatatata
     4981 cttttcaccc aagttctccc attgaggact cttgcttaaa aatatacaat ttgactttgg
     5041 tctgctcaca cacatgagtt ggcgagatcc caggaatgtc gtgtggtgat gatgttcact
     5101 gtttgtaacc atgctgttaa tgaacaagat ggtcattttg cctctagatt actcttgcct
     5161 agtttagtcc atgatgctat actcgtgaga gcatatccag atgctgtgtt ctctatttaa
     5221 aacagtattg tctgaacagg aatgtgtggc cctttattat ggatttcaac tacatgtaat
     5281 gatattccaa tattttcaat aaaggaattt atgcattcag tgtgaaaaaa aaaaaaaaaa
     5341 aaaaaaaaaa aaa
//
