LOCUS       NM_145555               1834 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus noncompact myelin associated protein (Ncmap),
            transcript variant 1, mRNA.
ACCESSION   NM_145555
VERSION     NM_145555.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1834)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1834)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   3  (bases 1 to 1834)
  AUTHORS   Ryu,E.J., Yang,M., Gustin,J.A., Chang,L.W., Freimuth,R.R.,
            Nagarajan,R. and Milbrandt,J.
  TITLE     Analysis of peripheral nerve expression profiles identifies a novel
            myelin glycoprotein, MP11
  JOURNAL   J Neurosci 28 (30), 7563-7573 (2008)
   PUBMED   18650334
  REMARK    GeneRIF: This study identified an evolutionarily conserved novel
            component of myelin called Mp11. The Mp11 genomic locus contains
            multiple conserved Egr binding sites, and Mp11 induction is
            regulated by the expression of Egr2 and expression in peripheral
            nerve.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK167453.1, AK039485.1 and BB093741.1.
            
            On Jan 15, 2010 this sequence version replaced NM_145555.1.
            
            Transcript Variant: This variant (1) encodes isoform 1. Variants 1,
            2, 3, 4 and 6 encode the same isoform.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167453.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1502              AK167453.1         2-1503
            1503-1831           AK039485.1         1146-1474
            1832-1834           BB093741.1         327-329
FEATURES             Location/Qualifiers
     source          1..1834
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 67.47 cM"
     gene            1..1834
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /note="noncompact myelin associated protein"
                     /db_xref="GeneID:230822"
                     /db_xref="MGI:MGI:2444888"
     exon            1..345
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /inference="alignment:Splign:2.1.0"
     exon            346..532
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /inference="alignment:Splign:2.1.0"
     exon            533..615
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /inference="alignment:Splign:2.1.0"
     CDS             540..842
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /note="isoform 1 is encoded by transcript variant 1;
                     myelin protein of 11 kDa"
                     /codon_start=1
                     /product="noncompact myelin-associated protein isoform 1"
                     /protein_id="NP_663530.1"
                     /db_xref="CCDS:CCDS18784.1"
                     /db_xref="GeneID:230822"
                     /db_xref="MGI:MGI:2444888"
                     /translation="MTTATTLGDAVFSLNMTRGEDALYKSSGAIVAAIVVVVIIIVTL
                     VLILLKMYNRRMRTRRELEPKSPKPPVPPALDPSSNGSQQPATVTFDPANVHVETR"
     exon            616..700
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /inference="alignment:Splign:2.1.0"
     exon            701..1834
                     /gene="Ncmap"
                     /gene_synonym="A330049M08Rik; Mp11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggctgggg tgtggagcag gtagggcgca gggcacggaa cgcgggggct tggaaggaca
       61 gcgcacaggg gctcaggccc gcggaagata gctctccgga cccccagggg tccccagcct
      121 ggcgcgcgcc ttggcgtgag ccggtagctg aaaggtcagc aacatctccc ggttgtctgc
      181 agacaccggt gcacagaggt gttcagggtg caagctgaga agcaccccga agctgggtgc
      241 attcggggct acatctctgg catgcggaaa gctggtggtt tccttgtccg ctcctacgaa
      301 gtcacaggga gcgacctgga ctcccggaag aaaagcctac gagaggaaca gagatgccat
      361 tgagagctgt cgctgccggc atgaggcaag atcggctctg gggttgctca ctgttcttct
      421 tgaaggagga gtgactggcc gccaccggca cctgaaccca gcacccagga ggtgaacccg
      481 gacggacctg aggaggatcc tgtgtcctgt gtccttggga gactactcac tggggcgaga
      541 tgaccacagc caccactttg ggggacgccg tcttctcgct gaacatgacc aggggagagg
      601 acgccctgta taagagctct ggagccatcg tggctgccat tgtggtggtt gtcatcatca
      661 ttgtcacctt ggtgctgatc ctgctgaaga tgtacaacag gagaatgagg accaggcggg
      721 agctggagcc caagagccca aagccacctg tccctcctgc cctggacccc agcagcaatg
      781 gcagccagca gcctgctact gtgaccttcg accctgccaa tgtccatgtg gagactcggt
      841 gaccctgcct tggcgccatt cctgcctctc tgcaaagagc tttgatgacc tgaaagtcca
      901 ctctgctggc agcttcacca agttctttct ggttgggtaa actgaggcac ccttcaaaca
      961 gcccctgcag cttgaagcca ccctcacctg tgctctggcc accccagcta tgtccacgtc
     1021 cctgctgcca ctcgaccaaa gctctgagga catttcttct gttacctgac gagaagcact
     1081 gagctgggga aactggtgtg agtctggttg tcgcctcaca agtgcgacgg ctagacagct
     1141 tgatagacag acatctgagt cttctgctca tggtcaggga gtgttaaaga gagtgttccc
     1201 cagggagcca ctgggagcat ctcaacttaa gggcatgtcc acagcttcct caatcccata
     1261 gccagatgca gggaaactaa cttggactaa ctagccacaa aaccaacttg gtagcatcta
     1321 actgatgcag tactagatgg ccactagcca gctcctaatg gccagtcagc gctctccccc
     1381 tttaacaaag ggtacagagg ctggataaag tggcacgtgc ctgtcatcac agtgctcagt
     1441 aaaagcggga acactgggat tgcaggacca gctttgacca cattcagaga tgcttctctt
     1501 ttaaaaaaaa aaaaaaaaga aagaaagaaa gaaaaagaat aaacagtatt cttcaaaact
     1561 tctacttcat taatagtcag aaggaagatg taccccgagg agcagaggct agctcaagga
     1621 tgagaagcat aggctagctc taggataaga attgttgcat tgctcaaggt cctgggctat
     1681 gtggtagctg ctctgggctc tttctgctgc cccaggcaga ctaccctgac cccccatttc
     1741 ctggctctct tttatttggt tgctaagctt ccctggcagt cctcttgcct ctggggacaa
     1801 gtattttgaa cccattaaac cttgtatttc ctgc
//
