LOCUS       NM_134009               2893 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus nicalin (Ncln), mRNA.
ACCESSION   NM_134009
VERSION     NM_134009.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2893)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC019501.1.
            
            On Jun 10, 2007 this sequence version replaced NM_134009.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019501.1, AK128887.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2893
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..2893
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /note="nicalin"
                     /db_xref="GeneID:103425"
                     /db_xref="MGI:MGI:1926081"
     exon            1..284
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1792
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /note="nicastrin-like protein; nicalin homolog; BOS
                     complex subunit NCLN"
                     /codon_start=1
                     /product="BOS complex subunit NCLN precursor"
                     /protein_id="NP_598770.1"
                     /db_xref="CCDS:CCDS36000.1"
                     /db_xref="GeneID:103425"
                     /db_xref="MGI:MGI:1926081"
                     /translation="MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAH
                     EFTVYRMQQYDLQGQPYGTRNAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALR
                     QSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETVVPVYFAVEDEALLSIYEQTQ
                     AASASQGSASAAEVLLHTATANGFQMVTSGAQSQAVSDWLITSVEGRLTGLGGEDLPT
                     IVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFSRLYTYKRTHAAYNLLFFASG
                     GGKFNYQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGRGSHLRLHVSKPPREGTLQ
                     HAFLRELETVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFTLSHLESHR
                     AGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQVQEE
                     QIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYD
                     QLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ"
     exon            285..475
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            476..620
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            621..715
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            716..796
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            797..900
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            901..989
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1308
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1309..1396
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1435
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1599
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1653
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1654..1732
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1733..2879
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2859..2864
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2879
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggacctcagc agccgcccat gccgagctga gtccgccgag cctcggccgc ttcccgtcgc
       61 cctccgtcgc tgccgccttt gcggcctgcc gcccgccggg atgttggagg aagcgggcga
      121 ggtgctcgag aacgtgctga aggcgtcgtg cctgccactc ggctttatcg tcttcttgcc
      181 cgccgtgttg ctgctcgtgg cgccgccgct gcccgccgcc gacgccgcgc acgagttcac
      241 cgtgtaccgc atgcagcagt acgacctgca gggccagcca tacggcacgc ggaatgcagt
      301 gctcaacaca gaggcccgca cggtggacgc agatgtgctg agccgccgct gcgtgcttat
      361 gcggctcctg gacttttcct atgagcacta tcagaaggct ctgcgacagt cagcaggtgc
      421 tgtggttatc atcctgcccc gggccatggc tgccgtgccc caggatgtcg tccggcaatt
      481 catggagatt gagcctgaga tgctggccat ggagactgtg gtccctgtgt actttgctgt
      541 ggaggacgag gcactgctgt ccatctatga gcagacccag gctgcctctg cctcccaggg
      601 ctctgcctct gccgctgaag tactgctgca cacggccaca gccaatggtt tccagatggt
      661 gaccagtgga gcccagagcc aggcagtgag cgattggctc atcaccagcg tggaggggcg
      721 gctaacgggg ctgggaggcg aggaccttcc caccattgtc atcgtggctc attacgacgc
      781 ctttggggta gccccatggc tgtccctggg cgcagactca aatgggagtg gcatctctgt
      841 gctgctggag ctggctcgcc tcttctcgcg cctctacaca tacaagcgca cacatgcagc
      901 gtacaacctc ctgttcttcg catccggagg gggcaagttc aactaccagg gcaccaaacg
      961 ctggcttgag gacagcctgg accacacaga ctccagcctc ctgcaggaca acgtagcctt
     1021 cgttctgtgc ctggacactg tgggacgtgg cagccacctg cgcctgcatg tgtccaagcc
     1081 tccacgggaa gggacactgc agcatgcctt cctgcgagag ctggagacgg tggctgcgca
     1141 ccagttccct gatgtcagct tctccatggt acacaagaag atcaatctag cggatgacgt
     1201 gcttgcctgg gaacacgagc gctttgccat ccgaaggctt cctgccttca cgctgtcaca
     1261 tctggagagc caccgtgcag ggcctcgcag cagcatcatg gatgtgcggt cccgggtgga
     1321 ctccaagacc ctgactcgga acacgaggat aatcgcggag gccctgacca gggtcatcta
     1381 caacctgaca gagaagggga cgcccccaga catgccagtg ttcacggagc agatgcaggt
     1441 ccaggaggag cagatagact cagtcatgga ctggctcacc aaccagccac gggccgccca
     1501 gcttctcgac aaggacggga cattcctgag cacactggag cactttctga gccgctacct
     1561 gaaggacgtg cgacagcacc atgtgaaggc tgacaagcgg gaccctgagt ttgtcttcta
     1621 tgaccagttg aagcaagtga tgaatgctta cagggtcaag ccagccatct ttgacctgct
     1681 gctggcattg tgcattgggg cataccttgg catggcgtac acagccgtcc agcacttcca
     1741 cgtgctatac aagacggtgc agagactgct gctcaaggcc aaggcacagt agcagtggcc
     1801 atgtacaggt ggcccaggag gtactattca cacacccaca gcggccagac cgaacgaacc
     1861 acagagggtt ttgatgggtc actaggatgc aaggacacct ctccctgtcc atttcgttga
     1921 atgaccctgg aggagagccc cgcacacctg cagatgagcc cactgggatg gaatgatggc
     1981 ccgggccacg tgcactgaag ggccacacac tagtgttggc ctccccagtg gctgggtccc
     2041 agaagccggt ctctgcggtt gtgcagaggc atccgctgtc agcctgcctc cccctagcgc
     2101 tggccagcac ctgacagtgt ctccctgctt ttcctcctca taccccgccc tgcctgttgt
     2161 cacatcctcc accactggac atacctggtc ccccagctga tctgagcccc ctgaggttct
     2221 gtcccctcct gcaagtgtcc cttcgctcag tcctgacgct ggtgactggg caggagttgg
     2281 tcctgttctg gagtgtgcag tcctgaggtc tccccacctt ccacccccca gcctcagttt
     2341 ccctacctgt gatacattct ggggagtcca cccctctgtc atagtgtctg atggaacagc
     2401 caggcccagc acagccctgg atgtccccaa caggatggcc ttgggagggg gacactagtg
     2461 ctgacggttg acctcaggga ccccacggtg aatcaattca atagcaatat gacccaagag
     2521 gtgtcaggct ggggaccagc tgaagaccag ctgcttctgt ccctcacgcc tgctgaggcc
     2581 tggcccaccc ccacccgctg tgggctgcct ctgctcagca gtgatggctg ccaccctcgt
     2641 ggcatgcgtg tcgtagagcg agagggctca gcctgctgcc ctggccctgg gcactcttgt
     2701 tctttctact cttaccctgg cagctggtta tgggtctgag gccagtgcca cctgtcactg
     2761 ggaaaggaca cagggcacgc ccccttcctc tgtcctcaca gggcatgggg atggatggcc
     2821 cctggggtgg ccgtgggtct gcagttggtg ggttacaaaa taaaagccat attgaaggaa
     2881 aaaaaaaaaa aaa
//
