LOCUS       NP_598770                563 aa            linear   ROD 27-APR-2025
DEFINITION  BOS complex subunit NCLN precursor [Mus musculus].
ACCESSION   NP_598770
VERSION     NP_598770.1
DBSOURCE    REFSEQ: accession NM_134009.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 563)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC019501.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019501.1, AK128887.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Mus musculus"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     Protein         1..563
                     /product="BOS complex subunit NCLN precursor"
                     /note="nicastrin-like protein; nicalin homolog; BOS
                     complex subunit NCLN"
                     /calculated_mol_wt=58581
     sig_peptide     1..42
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=4345
     mat_peptide     43..563
                     /product="BOS complex subunit NCLN. /id=PRO_0000019688"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VCM8.2)"
                     /calculated_mol_wt=58581
     Region          127..429
                     /region_name="M28_nicalin_like"
                     /note="M28 Zn-Peptidase Nicalin, Nicastrin-like protein;
                     cd03882"
                     /db_xref="CDD:349878"
     Site            241
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8VCM8.2)"
     Site            428
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8VCM8.2)"
     Site            523..543
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VCM8.2)"
     CDS             1..563
                     /gene="Ncln"
                     /gene_synonym="3100002P13Rik"
                     /coded_by="NM_134009.3:101..1792"
                     /db_xref="CCDS:CCDS36000.1"
                     /db_xref="GeneID:103425"
                     /db_xref="MGI:MGI:1926081"
ORIGIN      
        1 mleeagevle nvlkasclpl gfivflpavl llvapplpaa daaheftvyr mqqydlqgqp
       61 ygtrnavlnt eartvdadvl srrcvlmrll dfsyehyqka lrqsagavvi ilpramaavp
      121 qdvvrqfmei epemlametv vpvyfavede allsiyeqtq aasasqgsas aaevllhtat
      181 angfqmvtsg aqsqavsdwl itsvegrltg lggedlptiv ivahydafgv apwlslgads
      241 ngsgisvlle larlfsrlyt ykrthaaynl lffasgggkf nyqgtkrwle dsldhtdssl
      301 lqdnvafvlc ldtvgrgshl rlhvskppre gtlqhaflre letvaahqfp dvsfsmvhkk
      361 inladdvlaw eherfairrl paftlshles hragprssim dvrsrvdskt ltrntriiae
      421 altrviynlt ekgtppdmpv fteqmqvqee qidsvmdwlt nqpraaqlld kdgtflstle
      481 hflsrylkdv rqhhvkadkr dpefvfydql kqvmnayrvk paifdlllal cigaylgmay
      541 tavqhfhvly ktvqrlllka kaq
//
