LOCUS       NM_010880               8257 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus nucleolin (Ncl), mRNA.
ACCESSION   NM_010880
VERSION     NM_010880.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8257)
  AUTHORS   Zhu,J., Mo,L., Li,M., Wang,Y., Zhang,G., Tao,Z., Liao,X., Du,M. and
            He,H.
  TITLE     Long non-coding RNA Snhg15 promotes preosteoblast proliferation by
            interacting with and stabilizing nucleolin
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1871 (8), 119847 (2024)
   PUBMED   39288892
  REMARK    GeneRIF: Long non-coding RNA Snhg15 promotes preosteoblast
            proliferation by interacting with and stabilizing nucleolin.
REFERENCE   2  (bases 1 to 8257)
  AUTHORS   Tang,Y., Yin,L., Yuan,L., Lin,X. and Jiang,B.
  TITLE     Nucleolin myocardial-specific knockout exacerbates glucose
            metabolism disorder in endotoxemia-induced myocardial injury
  JOURNAL   PeerJ 12, e17414 (2024)
   PUBMED   38784400
  REMARK    GeneRIF: Nucleolin myocardial-specific knockout exacerbates glucose
            metabolism disorder in endotoxemia-induced myocardial injury.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8257)
  AUTHORS   Sengar,A.S., Kumar,M., Rai,C., Chakraborti,S., Kumar,D., Kumar,P.,
            Mukherjee,S., Mondal,K., Stewart,A. and Maity,B.
  TITLE     RGS6 drives cardiomyocyte death following nucleolar stress by
            suppressing Nucleolin/miRNA-21
  JOURNAL   J Transl Med 22 (1), 204 (2024)
   PUBMED   38409136
  REMARK    GeneRIF: RGS6 drives cardiomyocyte death following nucleolar stress
            by suppressing Nucleolin/miRNA-21.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8257)
  AUTHORS   Bernheim,S., Borgel,A., Le Garrec,J.F., Perthame,E., Desgrange,A.,
            Michel,C., Guillemot,L., Sart,S., Baroud,C.N., Krezel,W.,
            Raimondi,F., Bonnet,D., Zaffran,S., Houyel,L. and Meilhac,S.M.
  TITLE     Identification of Greb1l as a genetic determinant of crisscross
            heart in mice showing torsion of the heart tube by shortage of
            progenitor cells
  JOURNAL   Dev Cell 58 (21), 2217-2234 (2023)
   PUBMED   37852253
REFERENCE   5  (bases 1 to 8257)
  AUTHORS   Singh,V.P., Hassan,H., Deng,F., Tsuchiya,D., McKinney,S., Ferro,K.
            and Gerton,J.L.
  TITLE     Myc promotes polyploidy in murine trophoblast cells and suppresses
            senescence
  JOURNAL   Development 150 (11) (2023)
   PUBMED   37278344
REFERENCE   6  (bases 1 to 8257)
  AUTHORS   Pasternack,M.S., Bleier,K.J. and McInerney,T.N.
  TITLE     Granzyme A binding to target cell proteins. Granzyme A binds to and
            cleaves nucleolin in vitro
  JOURNAL   J Biol Chem 266 (22), 14703-14708 (1991)
   PUBMED   1860869
REFERENCE   7  (bases 1 to 8257)
  AUTHORS   Van den Eynde,B., Lethe,B., Van Pel,A., De Plaen,E. and Boon,T.
  TITLE     The gene coding for a major tumor rejection antigen of tumor P815
            is identical to the normal gene of syngeneic DBA/2 mice
  JOURNAL   J Exp Med 173 (6), 1373-1384 (1991)
   PUBMED   1903428
REFERENCE   8  (bases 1 to 8257)
  AUTHORS   Aitman,T.J., Hearne,C.M., McAleer,M.A. and Todd,J.A.
  TITLE     Mononucleotide repeats are an abundant source of length variants in
            mouse genomic DNA
  JOURNAL   Mamm Genome 1 (4), 206-210 (1991)
   PUBMED   1794049
  REMARK    Review article
REFERENCE   9  (bases 1 to 8257)
  AUTHORS   Biggiogera,M., Burki,K., Kaufmann,S.H., Shaper,J.H., Gas,N.,
            Amalric,F. and Fakan,S.
  TITLE     Nucleolar distribution of proteins B23 and nucleolin in mouse
            preimplantation embryos as visualized by immunoelectron microscopy
  JOURNAL   Development 110 (4), 1263-1270 (1990)
   PUBMED   2100262
REFERENCE   10 (bases 1 to 8257)
  AUTHORS   Bourbon,H.M., Prudhomme,M. and Amalric,F.
  TITLE     Sequence and structure of the nucleolin promoter in rodents:
            characterization of a strikingly conserved CpG island
  JOURNAL   Gene 68 (1), 73-84 (1988)
   PUBMED   2906027
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ084318.1, AK144894.1 and AC102609.7.
            
            On Jan 14, 2006 this sequence version replaced NM_010880.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144894.1, AK031606.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                CJ084318.1         33-123
            92-2995             AK144894.1         2-2905
            2996-3180           AK144894.1         2907-3091
            3181-5450           AK144894.1         3093-5362
            5451-8257           AC102609.7         153231-156037
FEATURES             Location/Qualifiers
     source          1..8257
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 43.94 cM"
     gene            1..8257
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="nucleolin"
                     /db_xref="GeneID:17975"
                     /db_xref="MGI:MGI:97286"
     exon            1..250
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..2356
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /codon_start=1
                     /product="nucleolin"
                     /protein_id="NP_035010.3"
                     /db_xref="CCDS:CCDS35646.1"
                     /db_xref="GeneID:17975"
                     /db_xref="MGI:MGI:97286"
                     /translation="MVKLAKAGKTHGEAKKMAPPPKEVEEDSEDEEMSEDEDDSSGEE
                     EVVIPQKKGKKATTTPAKKVVVSQTKKAAVPTPAKKAAVTPGKKAVATPAKKNITPAK
                     VIPTPGKKGAAQAKALVPTPGKKGAATPAKGAKNGKNAKKEDSDEDEDEEDEDDSDED
                     EDDEEEDEFEPPIVKGVKPAKAAPAAPASEDEEDDEDEDDEEDDDEEEEDDSEEEVME
                     ITTAKGKKTPAKVVPMKAKSVAEEEDDEEEDEDDEDEDDEEEDDEDDDEEEEEEEPVK
                     AAPGKRKKEMTKQKEAPEAKKQKVEGSEPTTPFNLFIGNLNPNKSVNELKFAISELFA
                     KNDLAVVDVRTGTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVR
                     AARTLLAKNLSFNITEDELKEVFEDAMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEE
                     KQGAEIDGRSVSLYYTGEKGQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEEVFE
                     KATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGSNSRSQ
                     PSKTLFVKGLSEDTTEETLKESFEGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAK
                     EAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFG
                     GRGGFRGGRGGGGDFKPQGKKTKFE"
     exon            251..367
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            368..863
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1049
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1136
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1278
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1403
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1527
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1528..1682
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..1806
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1928
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2055
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            2056..2279
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     exon            2280..8257
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2461..2466
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="hexamer: AGTAAA"
     polyA_site      2493
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="major polyA site"
     regulatory      3295..3300
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="hexamer: AATACA"
     regulatory      3323..3328
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="hexamer: AATGAA"
     polyA_site      3343
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
     polyA_site      3347
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
     regulatory      8050..8055
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="hexamer: AGTAAA"
     polyA_site      8071
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
     polyA_site      8126
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
     regulatory      8189..8194
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
                     /note="hexamer: ATTAAA"
     polyA_site      8224
                     /gene="Ncl"
                     /gene_synonym="B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl"
ORIGIN      
        1 cgcgagctct ggttggtgga gccgaagtca cgaggacccc cttcgtcgcc tttccagagg
       61 cgattactgg gcaggctcag tcttttgcct cagacgctag ctgtagctgg caggcggttg
      121 tacgtgctcc agagtcgtcg gtacccgcta ctgcagtcgc tttcgtgtgg cttccgctga
      181 gctcttccga gctgctcgct ctccacacgc gccgccgccg taatccgcca ccatggtgaa
      241 gctcgcaaag gctggcaaaa cccacggtga ggccaagaaa atggctcctc ctccaaagga
      301 ggtggaagag gatagtgaag atgaagaaat gtcagaagat gaagatgaca gcagtggaga
      361 agaggaggtt gtcatccctc agaaaaaagg caaaaaggct accacaaccc cagcaaagaa
      421 ggtggttgtt tcacaaacaa aaaaggctgc agttcccaca ccagctaaga aagcagctgt
      481 gaccccaggc aaaaaggcag tagccacacc agctaagaaa aacattacac cagccaaagt
      541 cattccaaca ccgggtaaga agggagctgc acaagcaaaa gcgttggtac caactcctgg
      601 taaaaaggga gctgccactc cagctaaggg ggctaagaac ggtaagaatg ccaagaagga
      661 agacagtgat gaggatgaag atgaagagga tgaagatgat agcgatgagg atgaagatga
      721 tgaggaagag gatgagtttg agccaccaat agtaaaagga gtgaagccag caaaagcagc
      781 tcctgctgct cctgcctcag aggatgagga agatgatgag gatgaagatg atgaggaaga
      841 tgatgatgaa gaggaggaag atgactctga ggaagaagtt atggagatca caacagccaa
      901 aggaaagaaa actcctgcaa aagttgttcc tatgaaagcc aagagtgtgg ctgaggagga
      961 ggatgatgag gaagaggatg aagatgacga ggatgaggat gatgaggaag aggatgacga
     1021 agatgatgat gaggaagaag aggaggaaga acctgttaaa gcagcacctg gaaaacggaa
     1081 gaaggagatg accaagcaga aagaagcccc tgaagccaag aaacagaaag tagaaggctc
     1141 agaaccaact acacctttca atctgttcat tggaaacctt aatccaaaca agtctgttaa
     1201 tgaattaaaa tttgccatca gtgaactttt tgctaaaaat gatcttgctg ttgtggatgt
     1261 cagaactggt acaaatagga aatttggtta tgtggacttt gagtctgctg aagacctaga
     1321 aaaggccttg gagctcactg gtttaaaagt gtttggcaat gaaattaaac tagaaaaacc
     1381 aaaaggaaga gatagtaaga aagttcgagc tgcaagaaca cttctagcca aaaacctctc
     1441 tttcaacatc actgaggatg aattaaagga agtgtttgaa gacgccatgg agatcagatt
     1501 agtcagccag gatgggaaaa gtaaagggat tgcttatatt gaatttaagt ctgaagctga
     1561 tgcagagaaa aatttggaag aaaagcaggg ggcagaaatt gatggacgat ctgtttcact
     1621 ctactatact ggagagaaag gtcaaaggca agagagaact ggaaagacca gcacttggag
     1681 tggtgaatca aagactttgg ttttaagtaa cctttcctac agtgcaacaa aagaaactct
     1741 tgaggaagta tttgagaaag caacttttat caaagtgccc cagaacccac atggcaaacc
     1801 taaagggtat gcatttatag aatttgcttc atttgaagat gctaaagaag ctttaaattc
     1861 ctgtaataaa atggaaattg agggcagaac aatcaggctg gagttgcaag gatccaattc
     1921 gagaagtcaa ccatccaaaa ctctgtttgt caaaggtctg tctgaggata ccactgaaga
     1981 gaccttaaaa gaatcatttg agggctctgt tcgtgcaaga atagtcactg atcgggaaac
     2041 tggttcttcc aaagggtttg gttttgtaga ctttaatagt gaggaagatg ccaaagctgc
     2101 caaggaggcc atggaagatg gagaaattga cggaaacaaa gttaccttgg actgggccaa
     2161 acctaagggt gaaggtggct ttggtggtcg aggtggaggc agaggaggtt tcggaggcag
     2221 aggtggaggc agaggtggaa gaggtggatt tggaggaaga ggccggggag gctttggagg
     2281 tagaggaggc ttccgaggcg gcagaggagg agggggagac ttcaagccac aaggaaagaa
     2341 gacgaagttt gaatagttcc ttccatccca ttctttccct cttcatttta aagaaaggac
     2401 tctggggttt ttactctgtt acctgttcaa tgacagagcc ttctaaggac attccaagac
     2461 agtaaagatc ctaaactctg ttgccagact taatacttcc tagaggttac atttggattg
     2521 ttgcttaaga gcttggcaag accaactctg cccagtggga atttcagttg tgttcctact
     2581 gctttcaaga attcccagct acaaatgtgg aaattggtgg ggaacagctt catcatgatt
     2641 ctgatctgga agatttaatt tgtatcttag aagggtgtgt actggaaaag tggttgatag
     2701 agcacatgga tcagtgctgg aaataccata caagagcttg tgtggtatgt aattctattc
     2761 ccagcataat aagaacaaac agtacagtgc aatctgaaat gacctggaca aggaatggta
     2821 ccccattggg ttgaaaaatt cacatagcca ggatggttgc acatgccttt aaccccagca
     2881 cttgggaggg agaggctggt agatctgagt ttgatctggt gtacagagag ttccagaaca
     2941 gccagggctg tttattagag aaaaaaccct gtcttgaaaa aacaagaaaa aaaaacctca
     3001 cagacaacca aatacagagt tttagccact gagtaccaag tctcagcagc aagctgggag
     3061 tgacgtaatc caatcccatg ggaggctaaa gcagtctatg acttcaatgc cagttgggtc
     3121 tgcagaactg agttgctgga tagtgaggga tacttagaaa ctttgtcttg aaaaaaaaaa
     3181 caagacctgt caaatttgag agaagctttg ggaaacaagg tttgtaagtt ccaacagagg
     3241 gaacagtggc ctttttgact taaaggttgt cagaggtcca gtttaactag ggataataca
     3301 gtggcccttg gcctgtgtac ttaatgaatt tttcagtgat ctatcaagga tgtttggttt
     3361 ttttgttttt tgtttgtttt gtataaggca tgggtgccta gataacctta atagaaactt
     3421 tcctgtaggt gtttttccaa gtcccactcc caacaaactg attttcaaga aagaccagtc
     3481 agctattctc aaccaaagac cctctgtagg gttgcgctta gcacctgtct ggtggcttga
     3541 gtatgtggta tgaccattgc agtcgcagtc ctgtctaaaa gtgaggatgg cgtgggcatt
     3601 agatttgtgt agcagggaac agtttggtgg gttcttttgc tgtggggagt ggagcccttg
     3661 attatgttaa cctccttgtt aaagattaat ggcatgtagc tgaaggcact cagctgtcat
     3721 taatcctaga aggcagacca atttgaggct aaggaattcc agaatagcca gtgctacaca
     3781 gaagaccccc aagactacaa tagcaaagga aaggttcaac tctggtgcta gcagacatca
     3841 tttttttgtg gattgaggac atagttaacc tataggatca tcagaagatt tacagttgaa
     3901 tagctctccc taaacgaggc agacatttta gaaaagcagc aaacctttct ggaaatggtt
     3961 gtttgctttc ttttctcatt cttccagcag gtggcaacat gagaactgaa gaaagggtgg
     4021 agggaaggca gttaatctgc cttcacctaa tagataaaca caaagctctt attctggtgg
     4081 tagagtagct tgtagaggtc ttttaaagag caacaaagct ttctcatttg aaagattcac
     4141 ttcagctggg cgtggtggcg cacgccttta gtcccagcac ttgggaggca gaggcaagtg
     4201 attttctgag tgagttcgag gccagcctag gtctacagag tgagttctag gacagccagg
     4261 gctacacaga gaaaccctgc ctcaaaaaac aaaaagattc actcctgacc atttatcacc
     4321 tgcttttgac tatacactac cccttcagtg tggctttttt cctacggatg ctagtgatag
     4381 gagttaccta atgtagtttt cagttcaatc tgcctgaacc ttttcaactc ttaaggaaca
     4441 taggcagatg ctaagggtgt aggtcttgac cctatactga ggtagaaagg aaggggaaat
     4501 ggaagaggag catgtactct ttacttctaa gctggatcta tagccttagg attaccatct
     4561 ataacaggct aatttcattc agttagtggt aaaacccttt gccatagaat aaaagggctc
     4621 tcaaggttct agtagtaaaa caagttttgg ttgctgtcct ccattaagtg cctactaaat
     4681 gataagtgat ggagaggatg gaactgattc caagaaatac tcaacagtga ggacttatag
     4741 gccacttaac ctgtgtgtgc ttgtgggata tttctacctt ttgaagcagg gtctcttatt
     4801 ttcttactca ctacaagctt tcaagtactt ctggcaatac gaatgggatt agcaatgcat
     4861 gccatttcag tggccttatc tgggtttcag gggtcctggt catcaggttc tcgctggtaa
     4921 atcttaaaga ccaccgtctt tttttttttt ttttttttga gacagggtct ttagctctgt
     4981 ggccatcatg gaactcaata ggtagactag gctgacctca agatgtctgc ctcttgagtg
     5041 ttgcattaaa ggcctgtgcc accatgtcag gctccattat agaaacacac tactatcaga
     5101 aggatgatag gctgaggccc attttttaac cctttgaaaa aaattctggc tgggcagtgg
     5161 tgacactgcc tttaatccca gcacttggga gacaggcagg tggatttctg agttcaaggc
     5221 cagctgggtc tatagagtaa gttccaggac agccagagct atacagagaa acaaaaaaaa
     5281 aacaagggtt tattggggag ggaagggaag tacttatttt gaataaggtt ttattgtgta
     5341 tccctgattg tctttgaaat taatttgctt caactcgaag tgctgagact gcaagtatgt
     5401 acaaccacag tactcttagg ttctaactga attctcaccc attatttttc aaatacggcc
     5461 tttcagtttt attctctact ggactcttag ataaccagat actggcattg aaactagttt
     5521 ttttctcttt gaatattaat ttggatacat tctattgttt tggattctag ttcactgatt
     5581 cttctgttag gccctttagt gaagctttca ggtgtcttta gttttttttt aatttgtgtg
     5641 tgtgggtata gtgtctgtat ttctccatgt gcatgcaatg ccacaggagg ccagaagagg
     5701 gtggatcttc caaccttttt ttttttttta aagattttta ttttatgtat atgagtacac
     5761 tgtagctgtc ttcagacaca ccagaagagg gcatagaatc ccattacaga ttattgagag
     5821 ccaccatgtg attactgggg attgaactca tgacctctga aagagcagtc agtgctctga
     5881 actactgagc catctcacca gccgccttca agttcttgtg aaccaccatg tgggtactgt
     5941 gaatcaaact tgtgttttct ggactcttaa cagctgagtc atctctctag cccttcaagt
     6001 gtttcctttc tcttctaggt ttccagttta tgaagccccc attttgtcat ttaaattctt
     6061 ttcctgcaaa ttcctataca tctacaatca ttgaagtcat ttgtaaattt ttttatgtgc
     6121 attagtattt ggtctttatg tgtgtgagga gtcagaccca ccatgttaca aacagttgtg
     6181 agctgctatg tgggtgctgg gaattgaact tgggtcccct ggaagagtga ccagtgccct
     6241 taagtcgccc cttatttgta gttttaacag gagttatggt tgagtacttg ttaggattat
     6301 gaagagttgt ttctctttca ttgcatgtct aaactggaca ttgacccata tttagaggcc
     6361 agccatgtgc taattcaagt acattttgta ctggcattct taagtagcta gcaaaatctg
     6421 agtttctgtt tttcatagaa tatgatgaga tttactttaa agccaggtaa tgtgtttatc
     6481 ctgagaatac cagctgtgta ttttcttgag ccaaccaaat tgaaagtgag gagtttcagt
     6541 gattaaacac tggctgttta catgcagaga accccagttc acttcccagc atccagatgc
     6601 tgcttgactg taactagttc cagggaccca aggtcctttt ctgctttttg ggcactttct
     6661 tgggtgctag caaaacaccc atatacataa aaatgaatag gaaaatgaaa aatttaggaa
     6721 aagttggaag cgattttatg tcaaatttac tgttcctgtt catggtcccc cccaaacttc
     6781 cagactcact cctcagtacc cctctgttgc ccagaaatcc ggctaatctt ggcacacctg
     6841 tagcgcgcca gactaaacac tgactttgag agtatgtgcc tcagttctat ctggtaatta
     6901 tttttatggt gcttggaatt agaccaggac cttggtttgt acatataatt aggtgattgc
     6961 agtttttctt gactttggtt tttttgtttt tttcctttac atttctgtca gatttctgtt
     7021 tttttgagac agggtctctc tcactatgta gctttggtta tcctagaact tactatttag
     7081 accagctggc ctttaattcc cagaggttca ttcacctctg ccttctgagt gctggcatca
     7141 aagagagtgg attcgtagct gttaatatca gctataaact tgatcagatt gataagtgtc
     7201 tagggcacta gggaattact ctacatgttg ctataacaga atacctgacc aaagcaattt
     7261 aaagaaaagg ggtttatttt gattcacagt tccagaatat agtccatcat ggcagggaca
     7321 aggacgacat gatgccagaa gcttgaagca gctggtcaca ttgcatctat agttagaaaa
     7381 agttgatgga tgcttgtatt cagctagctt tcctttccat gcagactagg actccaacct
     7441 agggatggtt ttacatacct gaggtaattc aagataatct cataggcata gccagaagtt
     7501 aacctgatct agataatttc ctacagatat gcttagaagc gtgtctattt ccttctagat
     7561 ccagttcagt tgacaatgtg gtttggcata ctctagggtg tgtgtgtgag tatttccaga
     7621 aaggactagc tgaactacaa acactcaccc taagccatga aatctggggc atggtggctg
     7681 ggatttgaac tcaggacctt tgctgagcca tccaccagcc ccaagtttct ctgtgtagcc
     7741 ctggctgtcc tggaactcac tctgtagacc aggctcagag atctgcctgt ttctgcctcc
     7801 caagtgctgg gattaaaggt gtgcgccgcc accgcctggt aaagcaattt tgataatctt
     7861 ttgtctctat tctatcataa cactcccagt gtctaatcat ttggaagggt gccatctcta
     7921 gtttcttttc ccatatcaaa gaaagtgcaa attttttagg ggcatcataa tggtaacttg
     7981 gacattaatt aggaagaaac tgcatttgtt ggttaaaaat atctgtaaag ggggccagtg
     8041 agttcaatta gtaaaggtgc ctgccaccaa acctgacagc ctgtgtttga tctctagaag
     8101 atgtaaaagc tgaaggagag aaacaatagg tttgtctggc ctctctgtag caagcatgta
     8161 cctgaacatg catatcactc atacagtaat taaacatcgg aatgattcac atccacaagg
     8221 taaactatgg gaaggataaa cctctagtaa acatgtc
//
