LOCUS       NM_025818               6284 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nuclear cap binding subunit 3 (Ncbp3), mRNA.
ACCESSION   NM_025818
VERSION     NM_025818.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6284)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6284)
  AUTHORS   Linden,J., Schnepf,D., Wischnewski,M., Ye,L., Gawron,J.,
            Ohnemus,A., Friedrich,C., Gasteiger,G. and Staeheli,P.
  TITLE     Interferon-lambda Receptor Expression: Novel Reporter Mouse Reveals
            Within- and Cross-Tissue Heterogeneity
  JOURNAL   J Interferon Cytokine Res 40 (6), 292-300 (2020)
   PUBMED   32364818
REFERENCE   3  (bases 1 to 6284)
  AUTHORS   Gebhardt,A., Bergant,V., Schnepf,D., Moser,M., Meiler,A., Togbe,D.,
            Mackowiak,C., Reinert,L.S., Paludan,S.R., Ryffel,B., Stukalov,A.,
            Staeheli,P. and Pichlmair,A.
  TITLE     The alternative cap-binding complex is required for antiviral
            defense in vivo
  JOURNAL   PLoS Pathog 15 (12), e1008155 (2019)
   PUBMED   31856218
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6284)
  AUTHORS   Gebhardt,A., Habjan,M., Benda,C., Meiler,A., Haas,D.A., Hein,M.Y.,
            Mann,A., Mann,M., Habermann,B. and Pichlmair,A.
  TITLE     mRNA export through an additional cap-binding complex consisting of
            NCBP1 and NCBP3
  JOURNAL   Nat Commun 6, 8192 (2015)
   PUBMED   26382858
  REMARK    GeneRIF: Study proposes the existence of an alternative cap-binding
            complex involving NCBP1 and NCBP3 that plays a key role in mRNA
            biogenesis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6284)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 6284)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ093775.1, AK153241.1, CN666791.1, AL670399.4 and AK081659.1.
            
            On Aug 1, 2009 this sequence version replaced NM_025818.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004766.1, AK153241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-386               CJ093775.1         87-472
            387-2755            AK153241.1         375-2743
            2756-3106           CN666791.1         212-562
            3107-3978           AL670399.4         104263-105134
            3979-5252           AK081659.1         1-1274
            5253-6284           AL670399.4         106409-107440
FEATURES             Location/Qualifiers
     source          1..6284
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.16 cM"
     gene            1..6284
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="nuclear cap binding subunit 3"
                     /db_xref="GeneID:66874"
                     /db_xref="MGI:MGI:1914124"
     exon            1..216
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            217..282
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            283..388
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            389..514
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            515..643
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            644..720
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            721..829
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            830..929
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1033
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1328
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1483
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1645
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..6284
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2735..2740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="hexamer: AATATA"
     regulatory      2742..2747
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="hexamer: ATTATA"
     polyA_site      2757
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
     polyA_site      2766
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="major polyA site"
     polyA_site      2922
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
     regulatory      2970..2975
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="hexamer: AATAAG"
     polyA_site      2992
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
     regulatory      4681..4686
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="hexamer: CATAAA"
     polyA_site      4705
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
     regulatory      5304..5309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5325
                     /gene="Ncbp3"
                     /gene_synonym="1200014J11Rik; C130061O14Rik"
ORIGIN      
        1 gcgggctttc ggtggtgcgg ccggctggca gctatggcgg ccgtccgcgg cctgcgagtg
       61 tctgtgaagg cggaggcccc cgctgggccg gctttggggc ttccgtcgcc cgaggtggag
      121 tccggtttgg agcgtggcga gccggagccc atggaagtgg aagaaggcga gctggaaatc
      181 gtgccggtgc ggcgctccct aaaggaactg ctcccggaca caagcagaag atatgaaaac
      241 aaggctggca gcttcatcac tgggatcgat gtcacctcca aggaagcaat tgaaaagaaa
      301 gaacagcgag ccaagcgctt ccactttcga gcagaagtaa atcttgccca gagaaatgta
      361 gccttggacc gagacatgat gaagaaagca attcccaagg tgagactgga gacaatctac
      421 atttgtggag tggatgaaat gagcacccag gatatcttct cctattttaa ggaatatcct
      481 ccagctcaca ttgagtggtt ggatgacacc tcctgcaatg tggtttggct ggacgagatg
      541 acggccacac gagctctcat caatatgagt tctctgccag cccaggataa gatgagaagc
      601 agagatgcca gtgaagacaa gtcgtcggag aagaacaaga aagacaagca ggaagacagt
      661 tcagatgacg acgagactga agaaggagaa gtggaagatg agaattcaag tgatgtagag
      721 ttggacacgt tgtctcaggt agaagaagag tctctgttac gaaatgatct tcgtccagct
      781 aacaaacttg ctaaaggaaa tagactattc atgagatttg ctacaaaaga tgacaaaaag
      841 gaacttggag cagccagaag aagtcaatac tacatgaagt atggaaatcc aaattatgga
      901 ggcatgaaag gaattcttag caattcatgg aagcgaagat atcattcccg tcgcattcag
      961 cgggatgtga tcaagaagag agccctgatt ggggatgacg ttggcttgac gtcgtataaa
     1021 caccgacatt ccggattagt gaatgttcct gaggaaccca ttgaggaaga ggaggaggag
     1081 gaggaggaag aggaggacca ggacatggat gccgatgaca gagtcgtggt ggagtaccat
     1141 gaggagctcc caggtctcaa gcagccccgt gagcggagcc tgtctaggcg atccagtgcg
     1201 agcagctcag actcagatga gatggactat gatctggaac tgaagatgat ttctactccc
     1261 tccccaaaga aaagcatgaa aatgaccatg tatgcagatg aagtagagtc ccaactgaaa
     1321 agtattagga atcccatgag ggcagatagt atatccacaa gcaatataaa aaaccgaatt
     1381 ggtaacaaat tgcctcctga gaaatttgca gatgtccgtc atctcttaga tgaaaagagg
     1441 cagcattcct gtccacggcc agcagtcagc agtactaaac cagatattcg ccagcggtta
     1501 ggaaaaagac cgtattctcc agagaaggct tttagtagta accaggtggt tcggagagag
     1561 ccctcttcag atgtacatag taggctaggt gttcccaggc aagatgttaa aggcctctac
     1621 tctgatactc gggagaggaa atcaggtggt ttgtggactc gcttaggatc tacacccaag
     1681 accaaagaaa agaacacgaa gaaagtggat cacagggcat ctggtgctga ggaagatgac
     1741 tcggagcttc agagagcatg gggtgctctg atcaaggaga aagaagagtc tcgccagaag
     1801 aagagtcggc tggatagctt gccttcgctc cagattgaag tcagccggga aagtagctct
     1861 ggttcagagg cagagtcctg atgccctggc cttggcaact gcccttaaat ctgacattct
     1921 tacataaggt ggggcgtgca gtgggaacct cccttgcagg agctggcgcc ctttcctcct
     1981 acctgcaccc tgaacacttg ctgtcctagt aggacagctt aagagtgtga tgagttttga
     2041 aggaagggtg tctctgtctt gtgctgcaga gttacagttc tgggtcctca agtcttcccc
     2101 accaccccac aagctttacc cttggagtta aaggcaaccc tccagatttt gtagacattt
     2161 tcttaatatt tttaacattg tgtcttttaa aagcaatgtt ttacacagtc atccaaagag
     2221 ccgagaactg aacttctcat tgttgccttg gccctgacag atcttgccag caccctgttc
     2281 caagaaaagt cagttctcag gtgcttactg gacagtcttt gagggggaag atgagggaag
     2341 ctgccagctc agccttccag ggccttagtg tggtggctaa gtctctcaga cctgacctga
     2401 gaccctcccg agtagatatg cttgcagcag cagtcagcag tggcttccat tcctcccggg
     2461 gggagtcttt tagagccttt tgctggctgg tagcctggtg taaagaccaa gttcagtgct
     2521 gtaggacttc tagggacaaa caactgtgac ttctggattt ggagttgatt tctgtgctta
     2581 ggggtggggt cttgggttga tgttgaacaa tttttaagtc tgtattatgt ttaaaaacta
     2641 ttaatgactt aaaagtttaa atttttaatt tttatatgtg gatattcctc ctgttggcta
     2701 aggggaagct caagtggtgt cttttgtgtt gttaaatata cattatatac tttggaagaa
     2761 ggcaaagaaa ggagtgtcat tattttgaat ggtaccaatt gtatggtctg ttgtacttga
     2821 gttcaacttg ctttgtggcc actgtaggaa agaaactgct gtccatctgt gatgggctct
     2881 tgtttattcc cacttttcta gaaatgatac cctgagaatt cactctttgt gtctctgact
     2941 tattattgaa gacttattca aaactagcaa ataagacagt agtttcagaa aatgtaagtt
     3001 tatgtttatt ctcctttcaa atgattttac catggaaagg gagtaagtag attatttggc
     3061 ttctcatctg actttacttt atagtattta atactgtatt gctctacagg cttaaaagtg
     3121 gtgtttcact tgagtgcata agcatgcctt tgggatgtca agctcttcac ctgctcggct
     3181 tgttctgtgc ccagtaggtc acagagcact tgacttgtgg ttgagcacgt gtcccttggt
     3241 ggctgcctac actgtgaatg aacagtgatg cacatgaaga agcagaagac ttcagaacta
     3301 agtcgtaaca aaactgtatc atatgtatca tttggttagc aaccccaccc cacccccatc
     3361 tccaccctac ccccagaaag atgggagcat ataaccaaag tggtttggct tctgaggatc
     3421 ctagaaaaag gtagttctaa tttctctgcc agttcagacc taagtcctcc aaggtttcta
     3481 agtttatctt gccctttgta gctcacagct tacagtcagg ttcttagagg ttcagacttt
     3541 ggtagagtaa gaagaaaaat ggcctgagaa cagagacctg gatgccaacc aggactctac
     3601 acactgggcc tgagccttgg tttccccatg aagcaaggaa atggtctggt gcagagattc
     3661 tggctttgtt gatatctctc agtggtattt tattcttgga agttgtggct gcagcatgtt
     3721 tttctgttga ggtggccaaa gtgtcaggga acaaggtggc catgagattg tgaacagaga
     3781 ctcaccccat ccgtttacag gctccagttc tcccagtgtg ttgaagatgt gcctgtgggg
     3841 tctagagccc caacccatcc tcagctttct tattgttcta tctggcaacc caggcccatt
     3901 tgcctagggt ctttgagcac ttgtcaacct cctgctagag atgaggggag gactttatgg
     3961 aaggtaggca gtatgtattc aaaactaact ccttgagctg accaggaaag atgcccttga
     4021 gcagcattgc agtttttaca gcacagacaa cccagaaacg tacatactgc ctaaagtgat
     4081 ggtctgccca gcatctctct ctccagccag ctctcagagc tgcccagagc ttcaacacct
     4141 tgaaccctat gtgcttagga gtgacagtag tcaggatagc ccagcaggca gctgggtata
     4201 ctttattcag ggcactttct gtacatgtgg ggttagtctt tatatgtagg agattattaa
     4261 atgccctttt gctgcttcat aataattgca gatacctcat ctttgtttcc tactactctt
     4321 ctttgtagag gggcctgatg gcctctggcc ctcctctatc ataattccat gattccttcc
     4381 cctgcttctg tctttccttt ctgcggcagc ttctctcaac cctccctctt cattctacac
     4441 attgtagtgg gggcaaattt ttacttgaga gatacgtaca tagtatgcag tttatccttg
     4501 tacagtgtac atttgattgt cgtctattta cagagctgtg gaaccattat catcatcagt
     4561 tttagaacat atttatcacc agaaaaatcc tgttcccact agcagtcctc cttcacctct
     4621 cctcagacct ggcaactact aatctttctg tccttgtgga tttgcctata acggaccttt
     4681 cataaatgtt atatgcgatg tgcaatgtgt ctgtttactt agttttaagg ttcatctgtg
     4741 ccatggtata tatcatcatt tcaagtagtg agtacctctc tctctctctc tctctttctc
     4801 tctctctctg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg cgcgtgtgcg cttagacatt
     4861 ttcattgtgt ggccctggct gcccttagaa caggctggtc ttgagttcac agaggaagct
     4921 ctgcttccca ggtgctggga ttaaaggtgt gtggcactgt gcctgccagt gggtttgttt
     4981 tgttttgtct tttctcttca gttttttaaa ttgtctaaat atttcattac agtgcatata
     5041 atgggcgttc tgtgatttct agtcaggacg atcatgaata ggcttctgta tatatgtgtg
     5101 tgcaacaccc cttcatgttc tccttcatgg acatgtgggg gttttggtgg tggtggaggt
     5161 gggtttttgt ttgtttgttt gtttttgttt ttgagacagg gtttccctgt gtaacaagct
     5221 ctgtctgtcc tggactcaat ttgtagacca ggctggcctc gaactcacag agaccctcct
     5281 gcctctgcta gccaagtgct gggattaaag gggtgcacca ccacacccag cgtgttttca
     5341 ttcttttgta taggaataga atggatggat cgtaaggcag ctcttacctt tagtctttgg
     5401 aggaattgcc aagctgtgtt cccatggagg atatcaggat tccagtttat caagtcttca
     5461 ccaatattgt ttactaattt gaagtgtgtt tcattgtgta tgtgctgtgt tttattttgt
     5521 ggcagtgcag gggaccagac ccaggacttg cagatgtaga caagtattgt accactgggc
     5581 tccatccaca gtcccttagc tggttctgag ttgcagtttc ctaataacta gtgatgttgg
     5641 ccattatgtc ttcctcttcc tcctgtgtct gtgtctgtgg ttttaagata gggtttcatg
     5701 tgttggacaa tatttttgtt ttgtcttttt tttttttcaa agatagaatt tctcaggctg
     5761 gggaaatagg cttacaacca aaaatataag agttcggttc ctagcaccca tagctgtctc
     5821 tccagccaca aaaaaaaaaa aaaagaaaaa gaatttctct gtgtagccct ggctgttctg
     5881 gaactccagg ctagcctcag agtcagagat ctgcctgcta ctgcctcctg agtgctggga
     5941 ttaaaggcat gcaccaccac gcctagctat gttgggcata ttttcatgta taacaagatg
     6001 aactcttaag atatcaatct gatcttaact atgcttgtgc ttgagacctt tccagaactt
     6061 catcattgtt tctggaataa aatttcaaac ttctgggctg gagagatggc tcagcggtta
     6121 agagcattga ctggctcttc tgaaggtccc gagttcaaat cccagcaacc acatggtggc
     6181 tcacaaccat ccataatgag atctgatgcc ctcttctggg gtgtctgaag acagctacag
     6241 tgtacttaca tataataaat aaataaataa ataaataaat aaat
//
