LOCUS       NM_001033201            3167 bp    mRNA    linear   ROD 19-DEC-2022
DEFINITION  Mus musculus nuclear cap binding protein subunit 1 (Ncbp1), mRNA.
ACCESSION   NM_001033201 XM_485377 XM_899073 XM_899079 XM_899091 XM_899098
            XM_899103 XM_899107 XM_907156 XM_920218 XM_920231 XM_920251
            XM_920260 XM_920269 XM_920279
VERSION     NM_001033201.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3167)
  AUTHORS   Gresakova V, Novosadova V, Prochazkova M, Prochazka J and Sedlacek
            R.
  TITLE     Dual role of Fam208a during zygotic cleavage and early embryonic
            development
  JOURNAL   Exp Cell Res 406 (2), 112723 (2021)
   PUBMED   34216590
REFERENCE   2  (bases 1 to 3167)
  AUTHORS   Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein MY, Mann A,
            Mann M, Habermann B and Pichlmair A.
  TITLE     mRNA export through an additional cap-binding complex consisting of
            NCBP1 and NCBP3
  JOURNAL   Nat Commun 6, 8192 (2015)
   PUBMED   26382858
  REMARK    GeneRIF: Study proposes the existence of an alternative cap-binding
            complex involving NCBP1 and NCBP3 that plays a key role in mRNA
            biogenesis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3167)
  AUTHORS   Pabis M, Neufeld N, Steiner MC, Bojic T, Shav-Tal Y and Neugebauer
            KM.
  TITLE     The nuclear cap-binding complex interacts with the U4/U6.U5
            tri-snRNP and promotes spliceosome assembly in mammalian cells
  JOURNAL   RNA 19 (8), 1054-1063 (2013)
   PUBMED   23793891
REFERENCE   4  (bases 1 to 3167)
  AUTHORS   Padmanabhan K, Robles MS, Westerling T and Weitz CJ.
  TITLE     Feedback regulation of transcriptional termination by the mammalian
            circadian clock PERIOD complex
  JOURNAL   Science 337 (6094), 599-602 (2012)
   PUBMED   22767893
REFERENCE   5  (bases 1 to 3167)
  AUTHORS   Lenasi T, Peterlin BM and Barboric M.
  TITLE     Cap-binding protein complex links pre-mRNA capping to transcription
            elongation and alternative splicing through positive transcription
            elongation factor b (P-TEFb)
  JOURNAL   J Biol Chem 286 (26), 22758-22768 (2011)
   PUBMED   21536667
REFERENCE   6  (bases 1 to 3167)
  AUTHORS   Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng
            EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC,
            Babbitt PC and Ferrin TE.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3167)
  AUTHORS   Segref A, Mattaj IW and Ohno M.
  TITLE     The evolutionarily conserved region of the U snRNA export mediator
            PHAX is a novel RNA-binding domain that is essential for U snRNA
            export
  JOURNAL   RNA 7 (3), 351-360 (2001)
   PUBMED   11333016
REFERENCE   8  (bases 1 to 3167)
  AUTHORS   Ohno M, Segref A, Bachi A, Wilm M and Mattaj IW.
  TITLE     PHAX, a mediator of U snRNA nuclear export whose activity is
            regulated by phosphorylation
  JOURNAL   Cell 101 (2), 187-198 (2000)
   PUBMED   10786834
REFERENCE   9  (bases 1 to 3167)
  AUTHORS   Flaherty SM, Fortes P, Izaurralde E, Mattaj IW and Gilmartin GM.
  TITLE     Participation of the nuclear cap binding complex in pre-mRNA 3'
            processing
  JOURNAL   Proc Natl Acad Sci U S A 94 (22), 11893-11898 (1997)
   PUBMED   9342333
REFERENCE   10 (bases 1 to 3167)
  AUTHORS   Chadwick BP, Obermayr F and Frischauf AM.
  TITLE     Nuclear cap binding protein maps close to the xeroderma pigmentosum
            complementation group A (XPA) locus in human and mouse
  JOURNAL   Genomics 35 (3), 632-633 (1996)
   PUBMED   8812508
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK169557.1, AK133991.1 and BC034658.1.
            
            [WARNING] On Oct 20, 2023 this sequence was replaced by
            NM_001033201.4.
            
            On Apr 11, 2007 this sequence version replaced NM_001033201.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133991.1, SRR1660817.35116.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1051              AK169557.1         2-1052
            1052-2601           AK133991.1         1008-2557
            2602-3167           BC034658.1         2044-2609
FEATURES             Location/Qualifiers
     source          1..3167
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 24.49 cM"
     gene            1..3167
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /note="nuclear cap binding protein subunit 1"
                     /db_xref="GeneID:433702"
                     /db_xref="MGI:MGI:1891840"
     exon            1..376
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     CDS             343..2715
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /note="NCBP 80 kDa subunit; 80 kDa nuclear cap-binding
                     protein"
                     /codon_start=1
                     /product="nuclear cap-binding protein subunit 1"
                     /protein_id="NP_001028373.2"
                     /db_xref="CCDS:CCDS18145.1"
                     /db_xref="GeneID:433702"
                     /db_xref="MGI:MGI:1891840"
                     /translation="MSRRRHSYENDGGQPHKRRKTSDANETEDHLESLICKVGEKSAC
                     SLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGG
                     EFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEED
                     VPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFSTTESYLKRRQKTHVPMLQVWT
                     ADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPH
                     TEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSYWKERKTCAA
                     QLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLA
                     QATEMLYMRLDTMSTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLTQDLESPKPKFVR
                     EVLEKCMRLSYHQHILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLSVAF
                     KSKATNDEIFSILKDVPNPNQVDDDDEGFRFNPLKIEVFVQTLLHLAAKSFSHSFSAL
                     AKFHEVFKTLAESDKGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIF
                     SSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSD
                     RKDGALEEQIERLQEKVEAAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSILTPWY
                     KNCIERLQQIFLQHHQTIQQYMVTLENLLFTAELDPHILAVFQQFCALQA"
     exon            377..465
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            466..566
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            567..723
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            724..831
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            832..953
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1023
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1239
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1337
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1401
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1512
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1577
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1640
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1715
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1819
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1942
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            1943..2045
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..2139
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            2140..2243
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            2244..2358
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2487
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            2488..2601
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
     exon            2602..3112
                     /gene="Ncbp1"
                     /gene_synonym="CBP80"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagtcgtcgg cgcaggggcc gccgggaaaa tcccgccggg cctgtataaa gccgaggcgg
       61 gatcgctgcg gcccggataa tttagctcgc tgtccagaag ggcccggggt ggaaagccgg
      121 aggaggcggc cgcaattgga cttgcagacg ccggccttcc actgcggagc ccatccggtg
      181 cccctctgca cgcgcttccg gcaggcgtcg taagcgagtg cgcctgcgcg ccgctcagtc
      241 cgcgcgcctc gccgctgacc gcgcaccggc cggccggcag cccgacggtt ctggggttgc
      301 aggcggctag caactcagat cggctgcgca ccagcaagca gcatgtcgcg gaggcggcac
      361 agctacgaga acgatggtgg acaacctcac aaaaggagga agacgtctga tgcaaatgaa
      421 actgaagatc atttggaatc tttaatatgc aaagtagggg aaaagagtgc ctgttcttta
      481 gagagcaatc tcgaaggcct ggctggtgtt ttagaagctg atcttcctaa ctacaagagc
      541 aagatcttaa ggctcctttg tacagttgca cgtctgttac ctgagaagct aacaatttac
      601 acaacattag ttggactgct gaatgccagg aattacaact ttggaggaga atttgtagaa
      661 gctatgattc gtcaacttaa agaatcacta aaagcaaata actataatga agctgtatat
      721 ttggtccgtt ttctgtctga tcttgtgaat tgtcatgtga tcgctgcccc gtctatggtt
      781 gctatgtttg agaattttgt aagtgtaact caggaagaag atgtgcctca agtgcgacgg
      841 gattggtatg tgtatgcgtt tctgtcatcc ttgccctggg ttggaaagga gttgtatgaa
      901 aaaaaagatg cagaaatgga ccgaatcttc tccaccactg aaagctatct caaaagacgc
      961 cagaagactc acgtgcccat gttacaagtc tggactgccg acaaaccaca tccacaggaa
     1021 gagtatttag attgcctgtg ggcccagatt cagaaattga aaaaagaccg gtggcaggag
     1081 aggcacatcc taagacccta ccttgccttt gacagcatcc tctgtgaagc tctgcagcac
     1141 aacctgcctc ctttcacacc gccgccccac acagaggact ccgtgtaccc gatgcccagg
     1201 gtcatcttca ggatgtttga ctacacagac gacccagaag gccctgttat gccagggagc
     1261 cattcggtgg agaggtttgt catcgaggag aatcttcact gcatcatcaa gtcctactgg
     1321 aaggaaagga agacttgcgc tgcccagctg gtgagctatc cagggaagaa caagatcccc
     1381 ttgaactacc acatagtgga ggtgatcttt gcagagctgt ttcagcttcc agcgcctcct
     1441 cacattgacg tgatgtacac tacactgcta atcgaactgt gcaaacttca gccgggctcg
     1501 ctgccccaag tgcttgcgca ggcgactgag atgctgtaca tgcgtctgga cacgatgagt
     1561 accacgtgtg ttgacaggtt tattaattgg ttttctcatc atctaagtaa ttttcaattc
     1621 cgttggagct gggaagattg gtcagattgt cttactcagg atcttgaaag tcccaaacca
     1681 aagtttgtaa gggaagttct agagaagtgc atgaggttgt cttaccatca acatatatta
     1741 gatattgttc ctcccacctt ctcagctctg tgtcctgcaa acccaacctg catttacaag
     1801 tatggagatg aaagtagcaa ttctcttcct ggacattccg tggcactctg tttatctgtt
     1861 gcttttaaaa gtaaggcaac caacgatgag atcttcagca ttctgaagga cgtaccaaac
     1921 cctaaccagg ttgatgatga tgatgaaggg ttcagattta accctttgaa aatagaggtc
     1981 tttgtccaga ctctgctgca cttagctgcc aagtccttca gtcactcctt cagtgctctt
     2041 gcaaagtttc atgaagtctt caaaactctg gcggagagtg ataaggggaa gctgcacgtg
     2101 ctgagagtca tgtttgaagt gtggaggaac catccacaga tgattgctgt gctggttgat
     2161 aagatgattc gtacgcagat tgtcgactgt gcagcagtag caaactggat cttctcatcg
     2221 gagctgtctc gggactttac gaggttgttt gtgtgggaaa ttttgcactc tacaattcgt
     2281 aagatgaaca aacatgttct gaagatccag aaagagctag aagaagctaa agagaaactg
     2341 gcgaggcagc acaaacgacg cagtgatgac gacgacagga gcagtgacag gaaggacggt
     2401 gccctggagg agcaaataga aaggctgcag gagaaggtgg aggctgctca gagtgagcag
     2461 aagaacctct tcctcgtcat cttccagcgt ttcatcatga tcttgaccga gcacttggta
     2521 cgatgtgaaa cggatgggac cagtatattg accccgtggt ataagaactg catagagagg
     2581 ctgcagcaga tcttcctaca gcatcaccag accatccagc agtacatggt gaccctggag
     2641 aacctgctct tcacggccga gttagaccct cacatcctgg ctgtgttcca gcaattctgt
     2701 gctctgcagg cctaacactc gcgtttcttc cctttttatt atcttgaaat aacttgtctt
     2761 atttttgatg gtttgaatgt ttgctttctt gtagtagcct ttcacttcct gatggaaatg
     2821 ggggaggaga gtgaggaata tgacgtgacc cttagttgcc ctgcagggca agtgtggctt
     2881 gctaacagcg atgttatgtt gaccgtagag ttgtacatat gtgagcacaa ctttcctgtg
     2941 ataaatttga tactttttct ccttagggca caaaacaaca gatttgaggt gtgtgaaatg
     3001 caaggtcggg cttgcaaaat agtagataca accgagggac tatccccagg gagccaactt
     3061 ttctctgctc ctgggaacat ggctggaata aactgcagtt atggttttta aaaaaaaaaa
     3121 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
