LOCUS       NM_144818               2678 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus non-SMC condensin I complex, subunit H (Ncaph), mRNA.
ACCESSION   NM_144818
VERSION     NM_144818.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2678)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2678)
  AUTHORS   Chen,Z., Ruan,W., Guo,C., Chen,K., Li,L., Tian,J., Hu,Z., Peng,D.
            and Zeng,X.
  TITLE     Non-SMC condensin I complex subunit H participates in
            anti-programmed cell death-1 resistance of clear cell renal cell
            carcinomas
  JOURNAL   Cell Prolif 56 (7), e13400 (2023)
   PUBMED   36642844
  REMARK    GeneRIF: Non-SMC condensin I complex subunit H participates in
            anti-programmed cell death-1 resistance of clear cell renal cell
            carcinomas.
REFERENCE   3  (bases 1 to 2678)
  AUTHORS   Macdonald,L., Taylor,G.C., Brisbane,J.M., Christodoulou,E.,
            Scott,L., von Kriegsheim,A., Rossant,J., Gu,B. and Wood,A.J.
  TITLE     Rapid and specific degradation of endogenous proteins in mouse
            models using auxin-inducible degrons
  JOURNAL   Elife 11, e77987 (2022)
   PUBMED   35736539
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2678)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2678)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2678)
  AUTHORS   Lu,B.C., Cebrian,C., Chi,X., Kuure,S., Kuo,R., Bates,C.M.,
            Arber,S., Hassell,J., MacNeil,L., Hoshi,M., Jain,S., Asai,N.,
            Takahashi,M., Schmidt-Ott,K.M., Barasch,J., D'Agati,V. and
            Costantini,F.
  TITLE     Etv4 and Etv5 are required downstream of GDNF and Ret for kidney
            branching morphogenesis
  JOURNAL   Nat Genet 41 (12), 1295-1302 (2009)
   PUBMED   19898483
  REMARK    Erratum:[Nat Genet. 2010 Apr;42(4):361]
REFERENCE   7  (bases 1 to 2678)
  AUTHORS   Onn,I., Aono,N., Hirano,M. and Hirano,T.
  TITLE     Reconstitution and subunit geometry of human condensin complexes
  JOURNAL   EMBO J 26 (4), 1024-1034 (2007)
   PUBMED   17268547
REFERENCE   8  (bases 1 to 2678)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 2678)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   10 (bases 1 to 2678)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928590.10.
            
            On Mar 11, 2022 this sequence version replaced NM_144818.3.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus. The alternative upstream start codon is well-conserved
            and is used by homologs. The update changes the protein length from
            723 aa to 731 aa, but the splice sites are unaffected.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028919.1, BC025060.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AL928590.10        107956-108044       c
            90-327              AL928590.10        101592-101829       c
            328-418             AL928590.10        101211-101301       c
            419-511             AL928590.10        100222-100314       c
            512-647             AL928590.10        99658-99793         c
            648-772             AL928590.10        98938-99062         c
            773-962             AL928590.10        97644-97833         c
            963-1054            AL928590.10        96147-96238         c
            1055-1257           AL928590.10        95232-95434         c
            1258-1406           AL928590.10        92184-92332         c
            1407-1513           AL928590.10        91613-91719         c
            1514-1636           AL928590.10        90639-90761         c
            1637-1747           AL928590.10        87667-87777         c
            1748-1921           AL928590.10        82592-82765         c
            1922-2038           AL928590.10        81461-81577         c
            2039-2130           AL928590.10        80211-80302         c
            2131-2206           AL928590.10        79953-80028         c
            2207-2678           AL928590.10        77916-78387         c
FEATURES             Location/Qualifiers
     source          1..2678
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 61.76 cM"
     gene            1..2678
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /note="non-SMC condensin I complex, subunit H"
                     /db_xref="GeneID:215387"
                     /db_xref="MGI:MGI:2444777"
     exon            1..89
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..2266
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /note="XCAP-H homolog; barren homolog protein 1;
                     chromosome-associated protein H"
                     /codon_start=1
                     /product="condensin complex subunit 2"
                     /protein_id="NP_659067.2"
                     /db_xref="CCDS:CCDS16693.2"
                     /db_xref="GeneID:215387"
                     /db_xref="MGI:MGI:2444777"
                     /translation="MRIPRSETMNSSFLKARGQQDVLSSPLERVPPASRPGKAPLGTP
                     KTPVLEDFPQNDDEKERMQRRRSRVFDLQFSTDSIHLASPNRNIDVSTTISKFTNTQI
                     TEHYSTCIKLSSENKITTKNAFGLHLIDFMSEILKQKDAEPTNFKVAAGTLDASTKIY
                     AVRVDAVHADVYRVLGGLGKDTPPQGEESHSGDGSTLETERTKKPAKPKKKQSCKTIE
                     QNLSNINVSEADGKCAVDPMFQKTAASFDECSTTGVFLSTLHCQDYRSELLFPSDMQT
                     LSSGEPLELPDLGFVDMTDLEASLQQCVEDRPLCPSLAGFQFTKWDSETHNESVSALV
                     DKFKKNDQVFDINAEAEDDEEDVPDGPLVEDFVDNDEPDLSAAGDHEEFRSWKELCQV
                     QSNQEEVISLEDRDIQVMCSFLSMKPGEYSYFSPRTMKMWAGPDHWRFRPRPKQDATS
                     CTEHKKKSAKKDFEINFDDDIDFDAYFQKTKAATILTKSTLENQNWKATTLPTDFHYE
                     TDNLIQLHLKPGKRSLKMDQDQKAKTEHYEEIEDYDYNNPNDTSNYCPGLQAADSDYE
                     EADDLFADPVGTLDLESDPKTTQENGHISPENQGVDITTYQELNLVAEPQKVNKIEIH
                     YAKTAKKMDMKKLKQSMWSLLTKFSRKEADTEANHTESGQEGAPEEVADEKKLSGLTK
                     DLQTRLPPLMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVMQGD"
     exon            90..327
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            328..418
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            419..511
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            512..647
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            648..772
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            773..962
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1054
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1257
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1406
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1513
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1636
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1747
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1921
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            1922..2038
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2130
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2206
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2678
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2640..2645
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /note="hexamer: AATAAA"
     polyA_site      2661
                     /gene="Ncaph"
                     /gene_synonym="A730011O11Rik; Brrn1; CAP-H; HCAP-H;
                     mCAP-H"
                     /note="major polyA site"
ORIGIN      
        1 gacgtcacgc ggcggttacc gcgcttggcg ctcgcgattt aaaacttact ccggagacgt
       61 ggagagcaag atgagaattc cgcgctcaga aacaatgaat agctcttttc tgaaggcccg
      121 aggacaacag gatgttcttt cctcaccttt ggaacgggtg cccccagcat cccggcccgg
      181 gaaggctcca cttggcactc ctaaaacccc agtcctcgaa gactttcctc agaatgacga
      241 tgaaaaggag cggatgcagc ggagacgctc cagggtcttt gacctgcagt tcagtacaga
      301 ttcgattcat ctggcctccc ctaacaggaa tattgatgtt tcaactacca tatctaagtt
      361 tacaaacaca cagattacag aacattactc tacctgtatc aagctttctt ctgaaaataa
      421 aatcactact aagaatgctt tcggcttgca tttgattgat ttcatgtcag agattctgaa
      481 gcagaaagat gcagaaccaa ccaactttaa agtggctgct ggcaccttgg atgccagcac
      541 caagatctat gctgtccgtg tggatgccgt ccatgctgat gtatacagag tccttggggg
      601 gctgggcaaa gacacaccac ctcaaggaga ggagagccac agtggagatg gaagtaccct
      661 tgaaacagaa aggactaaaa aacctgcaaa gccaaagaag aagcagtcct gcaaaaccat
      721 tgaacagaat ctcagcaata tcaatgtctc ggaagccgat gggaagtgtg cggtggatcc
      781 tatgtttcag aagacagcag cctcctttga tgaatgcagc acgactgggg tatttctctc
      841 cacgctgcac tgccaggact acagaagcga gctgctcttt ccttccgaca tgcagaccct
      901 ctcctcagga gagcccctcg agctgccgga tctgggtttc gtagacatga cagatttaga
      961 agcttccttg cagcagtgtg tggaagaccg cccgctctgc ccatccctgg ccgggttcca
     1021 gtttactaaa tgggacagcg aaacacataa tgagtctgtg tcggccctgg tggacaagtt
     1081 taagaagaat gatcaagtat ttgacatcaa tgctgaggct gaagacgatg aagaggatgt
     1141 ccctgatggg cccctggtgg aggattttgt tgacaatgat gagccagacc tttctgcagc
     1201 tggggaccat gaagagttcc ggagctggaa ggagctctgt caggtccaga gcaaccagga
     1261 agaagttatt tccctcgagg acagagacat ccaagtcatg tgctcctttt tatccatgaa
     1321 acctggggaa tattcctatt tcagtccccg gaccatgaag atgtgggctg gcccagatca
     1381 ctggcgcttc aggcctcgac ccaagcaaga tgctacctcc tgcacagagc acaaaaagaa
     1441 gagtgcaaag aaagactttg aaattaattt tgatgatgat attgattttg atgcatattt
     1501 tcagaaaaca aaggctgcta ccattctgac caagtccact ttggagaacc agaattggaa
     1561 agccaccact cttcccacag atttccacta tgaaactgat aatctgatcc agcttcacct
     1621 caaaccaggc aaaaggtcac ttaagatgga ccaggaccag aaggctaaga ctgagcacta
     1681 tgaggaaatt gaagactatg attacaacaa ccctaacgac acctccaact attgtcctgg
     1741 acttcaggct gctgacagtg attatgaaga ggcagacgat ttatttgcgg atccagtcgg
     1801 gacccttgac cttgagtctg atccaaagac aacacaagag aatggtcaca tttctcctga
     1861 aaaccaagga gtagatatca caacttacca agagttgaac ttggtggctg agcctcaaaa
     1921 ggtgaataaa atagaaattc attacgccaa gactgccaaa aagatggaca tgaagaagct
     1981 gaagcagagt atgtggagtc tgctgacgaa gttttctagg aaggaggctg acacagaggc
     2041 aaaccacact gaaagtggac aggaaggtgc ccccgaggaa gtggctgatg agaagaaact
     2101 cagtgggctc acaaaggacc tgcagacaag gctgcccccg ctcatggctc agaacctctc
     2161 catacccctg gcttttgcct gtcttctgca cttagcaaat gaaaagaatc tgaagctaga
     2221 aggcacagag gatctttctg atgttctggt gatgcaaggg gactgagtcc actttgagac
     2281 gtctgcagcg ggatgcccat ggcttcctgg tggccgtgga gaggtgctgg gcctgtagcg
     2341 tggctatagc caaccaccac ggtgctggtt ctcgggatgc caccacgcta ggaagctcca
     2401 tgctgttgga aggtctcacg tgggtaacgt ccacctagga gagggaagcc ctttagtctg
     2461 tacagacagt ctgatcttta tatccatgtg ctctggtcac tttctgtgac cgtcccactt
     2521 ttcattctgt actgtcgaga atcatttctc catagcctct ttctgtcctt aaagaattcc
     2581 cagatctatg tacataaaat ttatcatttt taaacttgta agtgtattta ataccccaaa
     2641 ataaaactat tctggcaagt gtctgagtgc ccagtaaa
//
