LOCUS       NM_001358881            1280 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus N-acetyltransferase 14 (Nat14), transcript variant 2,
            mRNA.
ACCESSION   NM_001358881
VERSION     NM_001358881.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1280)
  AUTHORS   Wiame,E., Tyteca,D., Pierrot,N., Collard,F., Amyere,M., Noel,G.,
            Desmedt,J., Nassogne,M.C., Vikkula,M., Octave,J.N., Vincent,M.F.,
            Courtoy,P.J., Boltshauser,E. and van Schaftingen,E.
  TITLE     Molecular identification of aspartate N-acetyltransferase and its
            mutation in hypoacetylaspartia
  JOURNAL   Biochem J 425 (1), 127-136 (2009)
   PUBMED   19807691
  REMARK    GeneRIF: Results indicated that NAT8L, but not NAT14, catalysed the
            synthesis of NAA from L-aspartate and acetyl-CoA.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157563.12.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.24424.1, BY239538.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AC157563.12        89488-89541
            55-176              AC157563.12        90110-90231
            177-1280            AC157563.12        90805-91908
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.85 cM"
     gene            1..1280
                     /gene="Nat14"
                     /note="N-acetyltransferase 14"
                     /db_xref="GeneID:269854"
                     /db_xref="MGI:MGI:3039561"
     exon            1..54
                     /gene="Nat14"
                     /inference="alignment:Splign:2.1.0"
     exon            55..176
                     /gene="Nat14"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..725
                     /gene="Nat14"
                     /codon_start=1
                     /product="probable N-acetyltransferase 14"
                     /protein_id="NP_001345810.1"
                     /db_xref="CCDS:CCDS20749.1"
                     /db_xref="GeneID:269854"
                     /db_xref="MGI:MGI:3039561"
                     /translation="MAPNHLSVREMREDEKPLVLEMLKAGVKDTENRVALHALTRPPA
                     LLLLAAASSGLRFILASFALALLLPVFLAVAAVKLGLRARWGSLPPPGGLGGPWVAVR
                     GSGDVCGVLALAPGANVGDGARVTRLSVSRWHRRRGVGRRLLAFAEARARAWAGSMGE
                     PRARLVVPVAVAAWGVAGLLEACGYQAEGGWGCMGYMLVREFSKDL"
     exon            177..1280
                     /gene="Nat14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1259..1264
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nat14"
                     /note="hexamer: AATAAA"
     polyA_site      1280
                     /gene="Nat14"
                     /note="major polyA site"
ORIGIN      
        1 agcaacgaag gaccagcaag aaaggagctg tgctaatcct cccaggcagg ccggcaggtg
       61 tacaacgtca gctcccttgg ggaggggcct gcctgggggc taccatggcc cctaaccacc
      121 tgtcagtgcg ggaaatgagg gaagatgaga agcccctggt gctggagatg ctgaaggctg
      181 gtgtaaaaga cacggaaaac cgtgtggccc tccacgctct gacacgacct ccagcccttc
      241 tcctcctggc tgcagccagc agcggactgc gcttcatcct ggcctccttc gccctggccc
      301 tcctgctgcc cgtgtttctg gctgtagccg ctgtgaagct gggtttgcga gcccgatggg
      361 gctctctgcc tccaccaggc ggcctgggag ggccctgggt ggctgtccgt ggctccggcg
      421 atgtgtgtgg agtcctggct ctggcccctg gtgccaacgt gggggatgga gcccgagtca
      481 cccgcctctc tgtctctcga tggcaccgtc gcaggggcgt gggcagaagg ctgctggcct
      541 ttgccgaggc tcgagcccga gcatgggctg gaagtatggg ggagcctcgg gcccggctcg
      601 tggtcccagt ggctgtagcc gcttgggggg tggcagggtt attggaggcc tgtggctacc
      661 aggcagaggg aggctggggc tgcatgggct atatgctggt tagggaattc agcaaagacc
      721 tgtgattaga gaccatgccc actggataga tgggcagaga accagcacct aaagaacacc
      781 tactgtgtgc caggcacttt acatcccccc ctcagtgtct acctagtctg ctgggctgat
      841 agtgaagcac cgaggttgat ggacttacat tcccagtgtg cctgccagct gcaatgagga
      901 ctctaaactc aagtagaaca aatcccttct tggtcttctg ggaccactag aggtcaccgt
      961 gtccagtcct ttgcctcacc cccactgccc cagtctgtat gcactgaaaa acgtcgggtt
     1021 ctgggtctac aaagcccctg ctgcctgtgt ttgaggtctg gaagggagat ttgaggaaag
     1081 agagagagag agagagagag agagagagag agagagagag agagagagag agagagagag
     1141 agagactaaa agttagagtc tgtgacaggg aactcccaaa ggggacagat cttctgggag
     1201 tgggtggggc caggagcaca gtgtctccaa gcccatctgg ttttttacac tgtttgttaa
     1261 taaaccctga aacttctgtg
//
