LOCUS       NM_001419376            3687 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus N-ethylmaleimide sensitive fusion protein attachment
            protein gamma (Napg), transcript variant 2, mRNA.
ACCESSION   NM_001419376 XM_011246806
VERSION     NM_001419376.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3687)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3687)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   3  (bases 1 to 3687)
  AUTHORS   Lin,S.S., Bassik,M.C., Suh,H., Nishino,M., Arroyo,J.D., Hahn,W.C.,
            Korsmeyer,S.J. and Roberts,T.M.
  TITLE     PP2A regulates BCL-2 phosphorylation and proteasome-mediated
            degradation at the endoplasmic reticulum
  JOURNAL   J Biol Chem 281 (32), 23003-23012 (2006)
   PUBMED   16717086
REFERENCE   4  (bases 1 to 3687)
  AUTHORS   Chae,T.H., Kim,S., Marz,K.E., Hanson,P.I. and Walsh,C.A.
  TITLE     The hyh mutation uncovers roles for alpha Snap in apical protein
            localization and control of neural cell fate
  JOURNAL   Nat Genet 36 (3), 264-270 (2004)
   PUBMED   14758363
  REMARK    Erratum:[Nat Genet. 2004 Apr;36(4):427]
REFERENCE   5  (bases 1 to 3687)
  AUTHORS   Gotte,M. and von Mollard,G.F.
  TITLE     A new beat for the SNARE drum
  JOURNAL   Trends Cell Biol 8 (6), 215-218 (1998)
   PUBMED   9695844
  REMARK    Review article
REFERENCE   6  (bases 1 to 3687)
  AUTHORS   Advani,R.J., Bae,H.R., Bock,J.B., Chao,D.S., Doung,Y.C.,
            Prekeris,R., Yoo,J.S. and Scheller,R.H.
  TITLE     Seven novel mammalian SNARE proteins localize to distinct membrane
            compartments
  JOURNAL   J Biol Chem 273 (17), 10317-10324 (1998)
   PUBMED   9553086
REFERENCE   7  (bases 1 to 3687)
  AUTHORS   Nehls,M., Pfeifer,D., Micklem,G., Schmoor,C. and Boehm,T.
  TITLE     The sequence complexity of exons trapped from the mouse genome
  JOURNAL   Curr Biol 4 (11), 983-989 (1994)
   PUBMED   7874497
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140554.3.
            
            On Mar 31, 2023 this sequence version replaced XM_011246806.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.3716522.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               AC140554.3         109563-109726
            165-232             AC140554.3         112168-112235
            233-317             AC140554.3         114321-114405
            318-335             AC140554.3         115076-115093
            336-366             AC140554.3         115742-115772
            367-476             AC140554.3         117881-117990
            477-543             AC140554.3         118113-118179
            544-614             AC140554.3         118656-118726
            615-693             AC140554.3         123503-123581
            694-843             AC140554.3         124043-124192
            844-923             AC140554.3         126014-126093
            924-1053            AC140554.3         126665-126794
            1054-3687           AC140554.3         128519-131152
FEATURES             Location/Qualifiers
     source          1..3687
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 35.95 cM"
     gene            1..3687
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /note="N-ethylmaleimide sensitive fusion protein
                     attachment protein gamma"
                     /db_xref="GeneID:108123"
                     /db_xref="MGI:MGI:104561"
     exon            1..164
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..1197
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /note="isoform 2 is encoded by transcript variant 2;
                     gamma-soluble NSF attachment protein; SNAP-gamma;
                     N-ethylmaleimide-sensitive factor attachment protein
                     gamma"
                     /codon_start=1
                     /product="gamma-soluble NSF attachment protein isoform 2"
                     /protein_id="NP_001406305.1"
                     /db_xref="GeneID:108123"
                     /db_xref="MGI:MGI:104561"
                     /translation="MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVA
                     FKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKAS
                     MMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKA
                     SRLLVRGRRFDEAALSIQKEKNIYKEIENYPTCYKVEFWSPAERTGTGTKRTGTDPRE
                     EEHLGKGNPLCVWPTQILAVGTWDRPKKTIAQVLVHLHRNDYVAAERCVRESYSIPGF
                     NGSEDCAALEQLLEGYDQQDQDQVSEVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKS
                     PATPQAKPDGAAGMAAEEEEDEYSGGLC"
     exon            165..232
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            233..317
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            318..335
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            336..366
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            367..476
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            477..543
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            544..614
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            615..693
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            694..843
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            844..923
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1053
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..3687
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3665..3670
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /note="hexamer: AATAAA"
     polyA_site      3687
                     /gene="Napg"
                     /gene_synonym="2400003O04Rik; SNARE"
                     /note="major polyA site"
ORIGIN      
        1 gtagtcccct ttcccggctt cctccgaggc gttcccacgc cgacgctccg ggtgtttttg
       61 ctgagatcta ggcggcttca ctcttcgcgt cagcaagcga ccgaggcgat ggcagcccag
      121 aagatcaacg aggggctgga gcatctggcc aaggcagaga agtacctgaa aactggtttt
      181 ttgaagtgga agccagatta tgacagtgcc gcttctgaat atgggaaagc agctgttgct
      241 tttaaaaatg ccaaacaatt tgagcaagca aaggatgcct gcctccggga agctgttgcc
      301 catgaaaata acagggctct ttttcatgct gccaaagctt atgagcaagc tggcatgatg
      361 ctgaaggaga tgcagaagct gcctgaggca gtgcagctga tcgagaaagc cagcatgatg
      421 tacctggaga acggcacccc ggacacagca gccatggccc tggagcgagc cggaaagctc
      481 atagagaatg tagacccaga gaaggctgta cagctgtatc agcagactgc caatgttttt
      541 gaaaatgagg agcgcctccg acaggcagtt gaactcctag gaaaggcctc cagactgctg
      601 gtacgagggc ggaggtttga tgaagctgca ctgtctattc agaaagaaaa aaatatttac
      661 aaggaaattg agaactaccc aacttgttat aaggttgagt tctggtctcc agctgaaaga
      721 actggcacgg gaaccaagag aacaggaaca gatcccaggg aggaggagca cttgggaaaa
      781 gggaatcccc tatgtgtgtg gcccacacaa atcttggccg tgggtacctg ggacagaccc
      841 aagaaaacaa ttgctcaggt cttagttcat ctacacagaa atgactatgt ggctgcagag
      901 aggtgtgtca gggagagcta cagcatacca ggctttaacg gcagtgagga ctgtgcggcg
      961 ctggagcagc tcctggaggg ctacgaccag caggaccaag accaagtgtc cgaggtctgc
     1021 aactcgcccc ttttcaaata catggacaat gattacgcta agctgggcct aagcttggtg
     1081 gtcccaggag gaggaatcaa gaagaagtcc cctgcgacac cccaggccaa gcctgatggt
     1141 gctgccggca tggctgctga agaggaggaa gacgagtact cgggaggcct gtgctagtac
     1201 cctgcctgag gagatgagga gatgaggaga cgggaatcct gacacgccgt tttcgtggaa
     1261 ttaggactca ttttgtgggc atctgcttca ctgaaatcct gacgttgaat gttaatatat
     1321 atgaagtttc atttccccaa accagccatt gtatctacta cctgtgaagc agtttttcct
     1381 ttccattgca agcagaaaac actgtcatat tttaataatg attttaagat ctataggcca
     1441 aattctagat aaattatatc ataagtaaag caggaaatag gtatacttag tcttttctct
     1501 tgggttcttg taatttattg ttagataatt ttctttgcat tttatttaat gtcacttcta
     1561 aacgtgctgg ggttttggta aaaaataata atttcaaact ggtctggttc tttcgatgtt
     1621 gtcacttggt gcccactcat gtccccacta agagtgtcag cagttccaaa gagagaggca
     1681 gacagcaggt cctcagcgga cactcctcca gactcttcat tagatgtctg actgaggaga
     1741 cggtgcatgg cgccacctga ccctgctcat gcgaccattg atggtcacag agccagtggg
     1801 agcgtggttg ttccctcaca ggctgtttac atgtgtgtgg aggatcaggc ccagattgga
     1861 cgtgctactc agtgacctag aaatggcact gtcagctcct cccattctct ctgtccactt
     1921 gcattgtacc cgagccttgt tggcaccatg gaccatgaag aggcagaaca aaaacacgag
     1981 agactctttt tctaggaata taaaccataa gaataaacaa catacttcaa tggagtgggg
     2041 ccttgtctca aggtaaaaaa gaaatttatc cgtcagcata ttagatacat tcaaattgtt
     2101 gagtcttttc ggaaacaagc tttggacaaa agctttataa tttttagctc agtagccctt
     2161 gtgtgtgact ataaaatatg gaaggtagca tattaaagtg ctgttgtaaa tgtcttcagc
     2221 cctcccaaaa aaagtattgc tttttctttt ttcttaacaa caaaaagtat gactgttcaa
     2281 acctacttgg ctcttgacca aaataggact aggtaagact atttatattt atctagaatg
     2341 acaggtgacg ttcctgccaa tctagtgtgc atgcatttct tacctccaaa gtaattttgg
     2401 tttggagtta ataatttaac atgagttatg ctaggtactg caaaaaataa aaagttagcc
     2461 aggagggaaa aaactggttt taaaagacat acttttggac tgggttacca gtctttcata
     2521 ctgcacagtt cgcccatggc tatttcctaa aagttagttt tgaagcattc ctctttttac
     2581 cctgtatggc taaggcccat tcatgcttcg tgaactgacg aggttgcaag cagtagtgca
     2641 tgctagagag tagtgctgaa tggaatagga ctgtcaccac actccaccat gaataaagca
     2701 tgcttagtca tgctagattc ctgaacccta ggaaaagcat tgctacggta ctggtcccct
     2761 tgttgtggga gtgctcctac agattggcat cctctgccag gtgggcttga gtggctgggt
     2821 gtctctgaac aatccctgtg cagattacag gtctgacaca aaacactaat gcaaggttta
     2881 tgctttcccc taagttacct gcaccggtct tttggtcacc agcttattct ctttaattac
     2941 attgagatta tgaataaagt ggtcttccaa atttgtattt aaaaagggaa ttggtatttc
     3001 caagatcaat attatgtttc aatccaacca gaaatactgg tgcttgttga agcaaattag
     3061 cagactttta aaatatattt ggcagtactc aaaagttact ttagactgtg ttatggccca
     3121 ggttattcaa taaaaccgtg tggagggtcg gttttacttg tatccaccat aaacagcaat
     3181 tctcaacgca ctctgaagca acagtgagct tggttttaaa cagcagagta tttaggcagt
     3241 gcccgcctcc cgccaccccc atcaggagcc agcgtgcagg attcaggtta ttttgcttgg
     3301 tgtctcagga acatttgtcc ctcgtgtgca ctttttattt ttctacttgt attaagtctt
     3361 cgttcttgtg agcttagtca gaaatggaaa acgtggtctt cacagcaagc agcgctctcg
     3421 cgccctccct aggaaagcct gcatgggttt gctcagactc acctagtgtt tagtgccctt
     3481 ctgtgttgag tgaagtcagc cagcagagca catttaatat attgaatttg taaatatgca
     3541 gagtatagta tttgtgtatg gaatctgtgc attatcatat tttttcagct tttttggtga
     3601 ataagatatt aatatgtcgt caatggaaat tagatgattg cttctgaagg aagataatta
     3661 tgaaaataaa acccaagact ctgtgaa
//
