LOCUS       NM_021432               1909 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleosome assembly protein 1-like 5 (Nap1l5), mRNA.
ACCESSION   NM_021432
VERSION     NM_021432.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1909)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1909)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1909)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   4  (bases 1 to 1909)
  AUTHORS   Cowley,M., Wood,A.J., Bohm,S., Schulz,R. and Oakey,R.J.
  TITLE     Epigenetic control of alternative mRNA processing at the imprinted
            Herc3/Nap1l5 locus
  JOURNAL   Nucleic Acids Res 40 (18), 8917-8926 (2012)
   PUBMED   22790983
  REMARK    GeneRIF: Allele-specific polyadenylation occurs at the imprinted
            Herc3/Nap1l5 locus.
REFERENCE   5  (bases 1 to 1909)
  AUTHORS   Shimogori,T., Lee,D.A., Miranda-Angulo,A., Yang,Y., Wang,H.,
            Jiang,L., Yoshida,A.C., Kataoka,A., Mashiko,H., Avetisyan,M.,
            Qi,L., Qian,J. and Blackshaw,S.
  TITLE     A genomic atlas of mouse hypothalamic development
  JOURNAL   Nat Neurosci 13 (6), 767-775 (2010)
   PUBMED   20436479
REFERENCE   6  (bases 1 to 1909)
  AUTHORS   Wood,A.J., Roberts,R.G., Monk,D., Moore,G.E., Schulz,R. and
            Oakey,R.J.
  TITLE     A screen for retrotransposed imprinted genes reveals an association
            between X chromosome homology and maternal germ-line methylation
  JOURNAL   PLoS Genet 3 (2), e20 (2007)
   PUBMED   17291163
REFERENCE   7  (bases 1 to 1909)
  AUTHORS   Wood,A.J. and Oakey,R.J.
  TITLE     Genomic imprinting in mammals: emerging themes and established
            theories
  JOURNAL   PLoS Genet 2 (11), e147 (2006)
   PUBMED   17121465
  REMARK    Review article
REFERENCE   8  (bases 1 to 1909)
  AUTHORS   Davies,W., Smith,R.J., Kelsey,G. and Wilkinson,L.S.
  TITLE     Expression patterns of the novel imprinted genes Nap1l5 and Peg13
            and their non-imprinted host genes in the adult mouse brain
  JOURNAL   Gene Expr Patterns 4 (6), 741-747 (2004)
   PUBMED   15465498
  REMARK    GeneRIF: Nap1l5 expression is localised mainly to the adrenal
            medulla, whilst Peg13 expression is observed more generally
            throughout the adrenal medulla and the outer cortical layers
REFERENCE   9  (bases 1 to 1909)
  AUTHORS   Beechey,C.V.
  TITLE     A reassessment of imprinting regions and phenotypes on mouse
            chromosome 6: Nap1l5 locates within the currently defined
            sub-proximal imprinting region
  JOURNAL   Cytogenet Genome Res 107 (1-2), 108-114 (2004)
   PUBMED   15305064
REFERENCE   10 (bases 1 to 1909)
  AUTHORS   Smith,R.J., Dean,W., Konfortova,G. and Kelsey,G.
  TITLE     Identification of novel imprinted genes in a genome-wide screen for
            maternal methylation
  JOURNAL   Genome Res 13 (4), 558-569 (2003)
   PUBMED   12670997
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU526293.1 and BC046332.1.
            
            On May 23, 2007 this sequence version replaced NM_021432.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            imprinted gene         :: PMID: 12670997, 15305064, 15465498
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                BU526293.1         4-53
            51-1909             BC046332.1         1-1859
FEATURES             Location/Qualifiers
     source          1..1909
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 27.9 cM"
     gene            1..1909
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
                     /note="nucleosome assembly protein 1-like 5"
                     /db_xref="GeneID:58243"
                     /db_xref="MGI:MGI:1923555"
     exon            1..1894
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..630
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
                     /codon_start=1
                     /product="nucleosome assembly protein 1-like 5"
                     /protein_id="NP_067407.1"
                     /db_xref="CCDS:CCDS20197.1"
                     /db_xref="GeneID:58243"
                     /db_xref="MGI:MGI:1923555"
                     /translation="MADPEKQGPAESRAEDEVMEGAQGGEDAATGDSAAAPAAEEPQA
                     PAENAPKPKKDFMESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKP
                     LLAKIQELTGEMEGCAWTLEGEDDEDDEEEDDEEEEEEEEAAAGATGGPNFAKK"
     regulatory      1682..1687
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1702
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
     regulatory      1870..1875
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1894
                     /gene="Nap1l5"
                     /gene_synonym="1110020M21Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcggacgtca ccacagccgt cagcgtttgc cgcatcttca gacgcactct ggaccagccg
       61 caatcacagc tgcaggacct ctctggacca gctctattgc agactgcgca accaccagac
      121 cactgcggca aacaagccca gctgagccga gcagtagcca tggccgaccc cgagaagcag
      181 ggacccgctg agagccgcgc cgaggacgag gtaatggaag gcgcccaggg tggcgaagat
      241 gccgcgaccg gtgacagtgc cgctgctccc gcggccgagg agccccaggc ccccgcggag
      301 aacgcgccca agcccaaaaa agactttatg gagagcttgc ccaattccgt gaaatgccgg
      361 gttctggcgc tcaaaaagct gcagaagcgc tgcgataaga tcgaggccaa gtttgacaag
      421 gaattccagg ctctggagaa gaagtacaac gatatctaca agcccctgct cgccaagatc
      481 caggagctca ccggagagat ggagggctgc gcgtggaccc tggagggaga ggatgatgaa
      541 gatgacgagg aagaggacga cgaggaggag gaggaggaag aagaggctgc agctggcgca
      601 actgggggtc ccaacttcgc caagaagtga gcacagcaag ctgacaggtg ataaatcccc
      661 tgcccctttt atttccaatg tcggcagact ttaaaaggct caggatttgc ccaaaataaa
      721 atgtgaatct attctgacat tcctaaaatt aaattgaatc aagtagattc tggctagccc
      781 gtttctaatc tgacttttat ttgtgtaaaa cagatgctaa aagacgtttt ttagaaaaaa
      841 aaaaaagcct aattaaactt ttttttttct ccctgctctt ctgtgagaac tggacttgag
      901 actgttgaaa ggttgtcagt tagatgggaa ttaaaagtgc gtcacacgtt gaaatccatt
      961 catcacacta caccagaaca tccaagctaa gacagaactc ttctcaatgc ttaattcttc
     1021 agtttcttta cattttccag cgcagaggaa aaggaaccca ggaacgacgt catctttaag
     1081 acttttgctt ttgcaaaccc agacatcagc tttacactcc agaggagcct tggcatggag
     1141 caagcctgga ctgacagcat ttactgatta tgtggctagg aaaactgcca tttcaagttg
     1201 tgaaaaaatg ttttaaatat ttgcatttac agaaagaaca tggtttcaaa aatgagggtg
     1261 tattccatgt ataatattgt caacacgtgt tcatctgtta tggtcccgtg ttacctgttt
     1321 tcttggtagt gtttgtttac aaaatcgtaa aaaattaccc caaatgtttt aaagtgttaa
     1381 attaccttat agcattttag aaatataatt tacttgaaga gatgtagaat gtagcaattc
     1441 tgtaaagcat gtgtatccag tgttgcctag tttgaccttt gtgaagtctt tttgtcttgt
     1501 agcttttagc aagtagctgt gaaaaccatc agaactcctc aatgaagcta atgtttggaa
     1561 aaagtatata cttgaagaac aaacccaagt gtgtaccccc aaccccagct cagaaataga
     1621 aagggtttaa gtttgcttgt attagctgtg ccttcattat tttgctatgt aaatgtgact
     1681 taataaatgg tgcaaaatta aattttattg cttgaggaca gacgggcata aaggaaggga
     1741 aaagacattt aatgtaaagg cctctagctt ctttgtgggt tttgagttgt ctgtgaacca
     1801 atgttctgta aagaaacaca aacttaaagt tgtttaccac tgtggtgtta acaaaacagt
     1861 attttcaaaa ataaaaaaat ccttgttatt ctgaaaaaaa aaaaaaaaa
//
