LOCUS       NM_008672               2335 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus nucleosome assembly protein 1-like 4 (Nap1l4),
            transcript variant 2, mRNA.
ACCESSION   NM_008672
VERSION     NM_008672.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2335)
  AUTHORS   Dominguez,F., Shiliaev,N., Lukash,T., Agback,P., Palchevska,O.,
            Gould,J.R., Meshram,C.D., Prevelige,P.E., Green,T.J., Agback,T.,
            Frolova,E.I. and Frolov,I.
  TITLE     NAP1L1 and NAP1L4 Binding to Hypervariable Domain of Chikungunya
            Virus nsP3 Protein Is Bivalent and Requires Phosphorylation
  JOURNAL   J Virol 95 (16), e0083621 (2021)
   PUBMED   34076483
  REMARK    GeneRIF: NAP1L1 and NAP1L4 Binding to Hypervariable Domain of
            Chikungunya Virus nsP3 Protein Is Bivalent and Requires
            Phosphorylation.
REFERENCE   2  (bases 1 to 2335)
  AUTHORS   Imaizumi,Y., Furutachi,S., Watanabe,T., Miya,H., Kawaguchi,D. and
            Gotoh,Y.
  TITLE     Role of the imprinted allele of the Cdkn1c gene in mouse
            neocortical development
  JOURNAL   Sci Rep 10 (1), 1884 (2020)
   PUBMED   32024956
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2335)
  AUTHORS   Voisinne,G., Kersse,K., Chaoui,K., Lu,L., Chaix,J., Zhang,L.,
            Goncalves Menoita,M., Girard,L., Ounoughene,Y., Wang,H.,
            Burlet-Schiltz,O., Luche,H., Fiore,F., Malissen,M., Gonzalez de
            Peredo,A., Liang,Y., Roncagalli,R. and Malissen,B.
  TITLE     Quantitative interactomics in primary T cells unveils TCR signal
            diversification extent and dynamics
  JOURNAL   Nat Immunol 20 (11), 1530-1541 (2019)
   PUBMED   31591574
REFERENCE   4  (bases 1 to 2335)
  AUTHORS   Barral,S., Morozumi,Y., Tanaka,H., Montellier,E., Govin,J., de
            Dieuleveult,M., Charbonnier,G., Coute,Y., Puthier,D., Buchou,T.,
            Boussouar,F., Urahama,T., Fenaille,F., Curtet,S., Hery,P.,
            Fernandez-Nunez,N., Shiota,H., Gerard,M., Rousseaux,S.,
            Kurumizaka,H. and Khochbin,S.
  TITLE     Histone Variant H2A.L.2 Guides Transition Protein-Dependent
            Protamine Assembly in Male Germ Cells
  JOURNAL   Mol Cell 66 (1), 89-101 (2017)
   PUBMED   28366643
REFERENCE   5  (bases 1 to 2335)
  AUTHORS   Ghasemzadeh,M., Kaplan,Z.S., Alwis,I., Schoenwaelder,S.M.,
            Ashworth,K.J., Westein,E., Hosseini,E., Salem,H.H., Slattery,R.,
            McColl,S.R., Hickey,M.J., Ruggeri,Z.M., Yuan,Y. and Jackson,S.P.
  TITLE     The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte
            migration through platelet thrombi
  JOURNAL   Blood 121 (22), 4555-4566 (2013)
   PUBMED   23550035
  REMARK    GeneRIF: Leukocyte migration is initiated by homotypic adhesive
            interactions between platelets, leading to the development of an
            NAP-2 chemotactic gradient within the thrombus body that guides
            leukocytes to sites of vascular injury.
REFERENCE   6  (bases 1 to 2335)
  AUTHORS   Day,C.D., Smilinich,N.J., Fitzpatrick,G.V., deJong,P.J., Shows,T.B.
            and Higgins,M.J.
  TITLE     The imprinted domain in mouse distal Chromosome 7: reagents for
            mutagenesis and sequencing
  JOURNAL   Mamm Genome 10 (2), 182-185 (1999)
   PUBMED   9922400
REFERENCE   7  (bases 1 to 2335)
  AUTHORS   Ainscough,J.F., John,R.M. and Surani,M.A.
  TITLE     Mechanism of imprinting on mouse distal chromosome 7
  JOURNAL   Genet Res 72 (3), 237-245 (1998)
   PUBMED   10036981
REFERENCE   8  (bases 1 to 2335)
  AUTHORS   Baty,C. and Watkins,H.
  TITLE     Familial hypertrophic cardiomyopathy: man, mouse and cat
  JOURNAL   QJM 91 (12), 791-793 (1998)
   PUBMED   10024943
REFERENCE   9  (bases 1 to 2335)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   10 (bases 1 to 2335)
  AUTHORS   Paulsen,M., Davies,K.R., Bowden,L.M., Villar,A.J., Franck,O.,
            Fuermann,M., Dean,W.L., Moore,T.F., Rodrigues,N., Davies,K.E.,
            Hu,R.J., Feinberg,A.P., Maher,E.R., Reik,W. and Walter,J.
  TITLE     Syntenic organization of the mouse distal chromosome 7 imprinting
            cluster and the Beckwith-Wiedemann syndrome region in chromosome
            11p15.5
  JOURNAL   Hum Mol Genet 7 (7), 1149-1159 (1998)
   PUBMED   9618174
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY073069.1, AJ002198.1, BQ746389.1 and BC089018.1.
            
            On Oct 22, 2013 this sequence version replaced NM_008672.2.
            
            Transcript Variant: This variant (2) contains an alternate 3'
            coding exon compared to variant 1, that causes a frameshift. The
            resulting isoform (b) has a shorter and distinct C-terminus
            compared to isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.26876.1, AK156835.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                BY073069.1         2-31
            31-1249             AJ002198.1         1-1219
            1250-1845           BQ746389.1         15-610
            1846-2309           BC089018.1         1797-2260
            2310-2335           AJ002198.1         2276-2301
FEATURES             Location/Qualifiers
     source          1..2335
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 88.24 cM"
     gene            1..2335
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /note="nucleosome assembly protein 1-like 4"
                     /db_xref="GeneID:17955"
                     /db_xref="MGI:MGI:1316687"
     exon            1..79
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            80..110
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1224
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /note="isoform b is encoded by transcript variant 2"
                     /codon_start=1
                     /product="nucleosome assembly protein 1-like 4 isoform b"
                     /protein_id="NP_032698.1"
                     /db_xref="CCDS:CCDS40197.1"
                     /db_xref="GeneID:17955"
                     /db_xref="MGI:MGI:1316687"
                     /translation="MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQER
                     LDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPL
                     FDKRREFITGDVEPTDAESAWHSENEEEDKLAGDMKNKVVIAEKEAATVEELNPKGIP
                     EFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTN
                     PVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGT
                     VRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLY
                     FTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKV"
     exon            111..169
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            170..269
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            270..411
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            412..498
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            499..630
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            631..702
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            703..842
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            843..988
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1011
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1131
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1161
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1218
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1254
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..2313
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2289..2294
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /note="hexamer: ATTAAA"
     polyA_site      2309
                     /gene="Nap1l4"
                     /gene_synonym="2810410H14Rik; D7Wsu30e; Nap2"
                     /note="major polyA site"
ORIGIN      
        1 aggtggtttt gttggcgacc acggcggtgc agccccggag cgagcttagg acaggcgcca
       61 ctgccgcagg aggcgcgagg ggacaaaggc gttcagatgg cagaaaacag tctttcagat
      121 ggaggccctg cagattctgt ggaagctgct aaaaatgcca gtaatacaga aaaactcaca
      181 gaccaggtga tgcagaaccc acaagtgctg gcagctttgc aggaacgtct tgacaacgtc
      241 tctcacactc cttctagtta catagaaact ttacctaaag ctgtcaaaag aagaattaat
      301 gccctgaagc agctccaggt gaggtgtgcg cacatagaag ctaagttcta cgaggaagtt
      361 catgacctgg agaggaagta tgcagccttg taccagcctc tatttgacaa gagaagagaa
      421 ttcatcactg gtgacgtgga gcccacagat gcagagtcag cgtggcacag tgagaatgag
      481 gaggaggaca agttggctgg agatatgaag aataaagtag tcatagctga gaaagaagca
      541 gcaacagtgg aagagctgaa ccccaaaggc atccctgagt tctggttcac catcttcaga
      601 aatgtggaca tgcttagtga gctggtgcag gaatatgatg aaccgatctt gaaacatctg
      661 caggatatta aagtgaagtt ttcagaccct ggacaaccta tgtcttttgt gctagagttt
      721 cactttgaac ccaacgacta cttcaccaat cctgtcctga cgaaaacgta caagatgaaa
      781 tcagagccag acaaggccga cccgttttct tttgaaggtc ctgaaattgt ggactgtgat
      841 gggtgtacaa tagactggaa gaaaggaaaa aatgtcacag tcaaaaccat caagaaaaag
      901 cagaagcaca agggccgggg caccgtacga accatcacca agcaagtgcc caatgagtcc
      961 ttcttcaact tcttcagccc cctgaaagcc tctggagatg gagaatctct ggatgaagat
     1021 tccgagttca ccttagcctc tgactttgaa attgggcact tttttcgtga gcgcatcgtg
     1081 ccacgggctg tcctctactt cactggggag gccatagagg atgatgacaa ttttgaagaa
     1141 ggcgaggaag gtgaagagga ggaattggaa ggtgatgaag aaggagaaga tgaggatgat
     1201 gctgatgtta accccaaggt gtaatttttg tgttaatcat tcatgcgttt ctagaaagaa
     1261 cccagccagc cagcggagtg caagcagcag tgagaagcag tgaccctgtg gggccgcctt
     1321 gtggatggct gtcaggaccg caggccgcag gcaggggcct cagtccctgc caaagcagaa
     1381 ttttgttgac agtgctgtga catctaacca tttccaagtg catgattcct ctcccctttc
     1441 ccttcttact ttgctaaact tgtacagtgg agactgctgc agttcagaat aggagattag
     1501 ttgtagcacc tgcagctttg gtgcctgaag atcacttggg gtggaccgag gttgtgcctg
     1561 ggattgacag agcctgtgat tgtgtgcacc cggccctccc tactggcaag gccccatgat
     1621 ttccagctgc tgaactgcgt gggaagctgc tccagctgct gtgccctagt catcgcccaa
     1681 gcactgtaga ggaagctgtg ctcgccttag agcatttttt ttcttgcgtt ttggttttag
     1741 gggtgggtgg gttgtggcac acacctctga ggccagagcc atcgggttca ccctcgtact
     1801 tatttattta cttgtgcttg gggagctttg gacttcactg tcctcccact tacgagacca
     1861 tgttgctgac ttgatcagga ggatgtgaca ccaagtggag ggaggctcat ggaggaagcc
     1921 ctgctgcttc ctgccaccaa ctgctgtgct gtgctgtgct gtgccatgca gactacatgt
     1981 tattgccgct ggaagttggc aggctgtagc caggggacag aagttctcct tcactaggga
     2041 tctctggcct gtggagtaca gcttcagctt gtactgtgca caccagggcc acacctgggt
     2101 ttggtgacca gttggtggtt ggtgtgtgtg gggggagggg tgtttctgag agtatggtgg
     2161 tgtctctggt agccaggaca gccatgtcca cagtgaccag ccatgtagag tgtgctcagc
     2221 cttacccaat aacacatttg taactgaata cggtgttttc aatttgtaca gaatagttag
     2281 gatattctat taaagttgtg aaacacaaac tgaaaaaaaa aaaaaaaaaa aaaaa
//
