LOCUS       NM_008671               2478 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus nucleosome assembly protein 1-like 2 (Nap1l2), mRNA.
ACCESSION   NM_008671
VERSION     NM_008671.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2478)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2478)
  AUTHORS   Carmona-Mora,P., Widagdo,J., Tomasetig,F., Canales,C.P., Cha,Y.,
            Lee,W., Alshawaf,A., Dottori,M., Whan,R.M., Hardeman,E.C. and
            Palmer,S.J.
  TITLE     The nuclear localization pattern and interaction partners of
            GTF2IRD1 demonstrate a role in chromatin regulation
  JOURNAL   Hum Genet 134 (10), 1099-1115 (2015)
   PUBMED   26275350
REFERENCE   3  (bases 1 to 2478)
  AUTHORS   Attia,M., Forster,A., Rachez,C., Freemont,P., Avner,P. and
            Rogner,U.C.
  TITLE     Interaction between nucleosome assembly protein 1-like family
            members
  JOURNAL   J Mol Biol 407 (5), 647-660 (2011)
   PUBMED   21333655
  REMARK    GeneRIF: Results identified several proteins interacting with
            NAP1L2, including the ubiquitously expressed members of the
            nucleosome assembly protein family, NAP1L1 and NAP1L4.
REFERENCE   4  (bases 1 to 2478)
  AUTHORS   Attia,M., Rachez,C., De Pauw,A., Avner,P. and Rogner,U.C.
  TITLE     Nap1l2 promotes histone acetylation activity during neuronal
            differentiation
  JOURNAL   Mol Cell Biol 27 (17), 6093-6102 (2007)
   PUBMED   17591696
  REMARK    GeneRIF: Data show that Nap1l2 associates with chromatin and
            interacts with histones H3 and H4, and loss of Nap1l2 results in
            decreased histone acetylation activity, leading to transcriptional
            changes in differentiating neurons.
REFERENCE   5  (bases 1 to 2478)
  AUTHORS   Wood,A.J., Roberts,R.G., Monk,D., Moore,G.E., Schulz,R. and
            Oakey,R.J.
  TITLE     A screen for retrotransposed imprinted genes reveals an association
            between X chromosome homology and maternal germ-line methylation
  JOURNAL   PLoS Genet 3 (2), e20 (2007)
   PUBMED   17291163
REFERENCE   6  (bases 1 to 2478)
  AUTHORS   Chureau,C., Prissette,M., Bourdet,A., Barbe,V., Cattolico,L.,
            Jones,L., Eggen,A., Avner,P. and Duret,L.
  TITLE     Comparative sequence analysis of the X-inactivation center region
            in mouse, human, and bovine
  JOURNAL   Genome Res 12 (6), 894-908 (2002)
   PUBMED   12045143
REFERENCE   7  (bases 1 to 2478)
  AUTHORS   Rogner,U.C., Spyropoulos,D.D., Le Novere,N., Changeux,J.P. and
            Avner,P.
  TITLE     Control of neurulation by the nucleosome assembly protein-1-like 2
  JOURNAL   Nat Genet 25 (4), 431-435 (2000)
   PUBMED   10932189
REFERENCE   8  (bases 1 to 2478)
  AUTHORS   Debrand,E., Chureau,C., Arnaud,D., Avner,P. and Heard,E.
  TITLE     Functional analysis of the DXPas34 locus, a 3' regulator of Xist
            expression
  JOURNAL   Mol Cell Biol 19 (12), 8513-8525 (1999)
   PUBMED   10567576
REFERENCE   9  (bases 1 to 2478)
  AUTHORS   Debrand,E., Heard,E. and Avner,P.
  TITLE     Cloning and localization of the murine Xpct gene: evidence for
            complex rearrangements during the evolution of the region around
            the Xist gene
  JOURNAL   Genomics 48 (3), 296-303 (1998)
   PUBMED   9545634
REFERENCE   10 (bases 1 to 2478)
  AUTHORS   Rougeulle,C. and Avner,P.
  TITLE     Cloning and characterization of a murine brain specific gene Bpx
            and its human homologue lying within the Xic candidate region
  JOURNAL   Hum Mol Genet 5 (1), 41-49 (1996)
   PUBMED   8789438
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL773526.11.
            
            On May 28, 2020 this sequence version replaced NM_008671.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK051439.1, AK131621.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2478              AL773526.11        159082-161559       c
FEATURES             Location/Qualifiers
     source          1..2478
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 45.97 cM"
     gene            1..2478
                     /gene="Nap1l2"
                     /gene_synonym="Bpx"
                     /note="nucleosome assembly protein 1-like 2"
                     /db_xref="GeneID:17954"
                     /db_xref="MGI:MGI:106654"
     exon            1..2478
                     /gene="Nap1l2"
                     /gene_synonym="Bpx"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..1726
                     /gene="Nap1l2"
                     /gene_synonym="Bpx"
                     /note="brain-specific protein, X-linked"
                     /codon_start=1
                     /product="nucleosome assembly protein 1-like 2"
                     /protein_id="NP_032697.2"
                     /db_xref="CCDS:CCDS53164.1"
                     /db_xref="GeneID:17954"
                     /db_xref="MGI:MGI:106654"
                     /translation="MAESVDHKELSESNQEELGSQVMAEGPGESQDRSEGVSIEPGDG
                     GQHGEETVAAGVGEEGKGEEAAAGSGEDAGKCGGTDEDSDSDRPKGLIGYLLDTDFVE
                     SLPVKVKCRVLALKKLQTRAAHLESKFLREFHDIERKFAEMYQPLLEKRRQIINAVYE
                     PTEEECEYKSDCEDYFEEEMDEEEETNGNEDGMVHEYVDEDDGYEDCYYDYDDEEEEE
                     EEDDSAGATGGEEVNEEDPKGIPDFWLTVLKNVEALTPMIKKYDEPILKLLTDIKVKL
                     SDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLACYDPHPYRGTAIEYATGCDID
                     WNEGKNVTLRTIKKKQRHRVWGTVRTVTEDFPKDSFFNFFSPHGISLNGGDENDDFLL
                     GHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDEIYDKIIYDDWMAAIEEVKACCKN
                     LEALVEDIDR"
     regulatory      2459..2464
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nap1l2"
                     /gene_synonym="Bpx"
                     /note="hexamer: AATAAA"
     polyA_site      2478
                     /gene="Nap1l2"
                     /gene_synonym="Bpx"
                     /note="major polyA site"
ORIGIN      
        1 gtaatcatac tgcggcacca gttcctccat ccctccgccc ccgagtggct ggagcagctg
       61 cttgcggagg tctgcccact gcggctctct gcagtctcta gcctgttcct tcagggccta
      121 gagtctccgc ccagacagcc ggtttcaatt ctgctatccc agcttcagca ccgtctttta
      181 tccccactgc ttgctgcctg ccatcagtgc agccgccgcc gcctcttggt tcatctctgc
      241 cagatcatcg cgcatctgct gtattggtga gtcttcctgc ggaggtcagg tctcctgatc
      301 tgcgggctta gccaccataa gtgcaggcga tcgtttgaaa acaatggctg aatcagtcga
      361 ccataaagaa ctgtctgaat ccaaccaaga agagcttggc agccaggtaa tggcggaggg
      421 gcccggggaa agtcaggacc gcagtgaagg tgtctccatt gagcctggag atggcgggca
      481 acatggtgaa gaaaccgtgg ctgctggagt aggggaagag ggaaaaggtg aagaagctgc
      541 tgcagggtct ggggaagatg ctgggaagtg cggaggcact gatgaggact cagactcaga
      601 ccgtccaaaa ggacttatcg gttatctttt agataccgat ttcgttgaaa gtctcccagt
      661 gaaagttaag tgccgagtgc tagctcttaa aaagcttcaa acaagagctg cccatttgga
      721 atccaaattc ctgagggaat ttcatgacat tgaaaggaag tttgctgaaa tgtaccaacc
      781 cttactagaa aaaagacgac agatcatcaa tgcagtctat gagcccacag aagaggaatg
      841 tgagtataaa tcggactgtg aggactattt tgaggaggag atggatgagg aggaagagac
      901 taacggcaac gaagacggta tggtgcatga atacgtggat gaagatgatg gttatgagga
      961 ctgttattat gattatgatg acgaggaaga agaggaggag gaagatgaca gcgctggggc
     1021 caccggagga gaagaggtta acgaagagga tcctaagggg attccggatt tttggttgac
     1081 tgttttaaaa aatgttgaag cactcactcc tatgattaag aaatatgatg agcctattct
     1141 gaagctgctg acagatatta aagtgaagct ttcggatccc ggggagcctc tcagcttcac
     1201 actcgaattt cacttcaagc ccaatgaata ttttaaaaat gagctgttga caaagactta
     1261 tgtgctgaag tcaaagcttg catgctacga tccccaccct tataggggaa ctgccattga
     1321 gtacgccact ggctgcgaca tagattggaa cgaagggaag aatgtcactt tgagaaccat
     1381 caagaagaag cagagacatc gcgtctgggg aactgtccga actgtgactg aagattttcc
     1441 caaggactct ttcttcaatt tcttctctcc tcatgggatc agcttaaatg gaggggatga
     1501 aaatgatgat tttttacttg gtcataatct gcgtacttac ataattccaa gatcagtgtt
     1561 atttttctca ggagatgcac ttgaatctca gcaggagggt gtagttaggg aagttaatga
     1621 cgaaatatat gacaaaatta tttatgatga ttggatggct gcaattgaag aggttaaagc
     1681 ctgttgcaaa aatcttgagg cattagtaga agatattgat cgttaaaaca gagtagatgc
     1741 ttttgaaact aactgctcta catgcagtta ctgaagacat aagcagttaa tattgtcttg
     1801 tgttctgcat tttttcctgt catgccagtt taaaaattca aatactaatt aatctgacct
     1861 tgcattgtag tggtatgatg ttttcaagac atgtagactg tgataaatga ttaagacatt
     1921 aatagtctgt agtataaccc ttctgaagtc cttgtgccat gtatctatta atctgtggct
     1981 gtgaatatta ttagaagtgc taaatgagat tatttgtttg caaagaaaat attggaaacc
     2041 tacctaagag tgctttgcta ttttccccct tatcctctta gtgctttggc caattgactt
     2101 tattgtgcct gcttcatttt gcagtaaata tgcagtagaa tttaaaactt gaatgcctaa
     2161 gaggcctgca tatgattgag aatttcaggc aaaatcatat ttattattga taacagctag
     2221 tgcaaggctt ctgattgtat gtgactgtga taaataataa aactcaattg tattgaagtt
     2281 actgtttatc attgacatgt gagttacagt attttcaaat gttgcaaata ttgtcctgtg
     2341 taattgtgta aactgtgatt acagtgtaca tttttttcat aatatactga atcattcatt
     2401 gaaatggaca ctttaccatt tctgaaaata catttcatat tctgttcatt cactgaaaaa
     2461 taaaatgaat aaaaattt
//
