LOCUS       NM_013796               2152 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus N-acetylglucosamine-1-phosphodiester
            alpha-N-acetylglucosaminidase (Nagpa), transcript variant 1, mRNA.
ACCESSION   NM_013796
VERSION     NM_013796.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2152)
  AUTHORS   Pantaleon,M., Tan,H.Y., Kafer,G.R. and Kaye,P.L.
  TITLE     Toxic effects of hyperglycemia are mediated by the hexosamine
            signaling pathway and o-linked glycosylation in early mouse embryos
  JOURNAL   Biol Reprod 82 (4), 751-758 (2010)
   PUBMED   20032283
REFERENCE   2  (bases 1 to 2152)
  AUTHORS   Boonen,M., Vogel,P., Platt,K.A., Dahms,N. and Kornfeld,S.
  TITLE     Mice lacking mannose 6-phosphate uncovering enzyme activity have a
            milder phenotype than mice deficient for
            N-acetylglucosamine-1-phosphotransferase activity
  JOURNAL   Mol Biol Cell 20 (20), 4381-4389 (2009)
   PUBMED   19710420
  REMARK    GeneRIF: UCE -/- mice were viable, grew normally & lacked
            detectable histologic abnormalities, but plasma levels of 6 acid
            hydrolases were elevated. UCE accounts for all the uncovering
            activity in the Golgi.
REFERENCE   3  (bases 1 to 2152)
  AUTHORS   Kornfeld,R., Bao,M., Brewer,K., Noll,C. and Canfield,W.
  TITLE     Molecular cloning and functional expression of two splice forms of
            human N-acetylglucosamine-1-phosphodiester
            alpha-N-acetylglucosaminidase
  JOURNAL   J Biol Chem 274 (46), 32778-32785 (1999)
   PUBMED   10551838
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK032158.1, AK138035.1 and AC124576.4.
            
            On Jun 25, 2009 this sequence version replaced NM_013796.2.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the functional protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032158.1, AK087468.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AK032158.1         2-9
            9-2149              AK138035.1         2-2142
            2150-2152           AC124576.4         105722-105724
FEATURES             Location/Qualifiers
     source          1..2152
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.51 cM"
     gene            1..2152
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /note="N-acetylglucosamine-1-phosphodiester
                     alpha-N-acetylglucosaminidase"
                     /db_xref="GeneID:27426"
                     /db_xref="MGI:MGI:1351598"
     exon            1..116
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            117..575
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            576..715
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            716..824
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            825..953
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1159
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1207
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1309
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1373
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..2152
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2124..2129
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /note="hexamer: AATAAA"
     polyA_site      2146
                     /gene="Nagpa"
                     /gene_synonym="UCE"
                     /note="major polyA site"
ORIGIN      
        1 gagcccacgt gaccggagca ccaatccaat atggcggcgc ccagggggcc cgggctgttc
       61 ctcatacccg cgctgctcgg cttactcggg gtggcgtggt gcagcctaag cttcggggtt
      121 tcccgcgacg atgacctgct gctgccttac ccactagcgc gcagacgtcc ctcgcgagac
      181 tgcgcccggg tgcgctcagg tagcccagag caggagagct ggcctccgcc acccacgaac
      241 cccggcgcca gccaccacgc ggccgtgcgc accttcgtgt cgcacttcga ggggcgcgcg
      301 gtggccggcc acctgacgcg ggtcgccgat cccctacgca ctttctcggt gctggagccc
      361 ggaggagccg ggggctgcgc gcagaagcgc cgcgctactg tggaggacac agccgtcccg
      421 gccggttgcc gcatcgctca gaacggtggc ttcttccgca tgagcactgg cgagtgcttg
      481 gggaacgtgg tgagcgacgg gcggctggtg agcagctcag ggggactgca gaacgcgcag
      541 ttcggtatcc gacgcgatgg aaccatagtc accgggtacc tgtctgagga ggaggttctg
      601 gatcccgtga atccgttcgt gcagctgctg agcggagtcg tgtggctcat ccgcaatgga
      661 aacatctaca tcaacgagag ccaagccatc gagtgtgacg agacacagga gacaggttct
      721 tttagcaaat ttgtgaatgt gatgtcagcc aggacagccg tgggtcatga ccgtgagggg
      781 cagcttatcc tcttccatgc tgatggacag acggaacagc gtggccttaa cctatgggag
      841 atggcagagt tcctgcgtca acaagatgtc gtcaatgcca tcaacctgga tggaggcggt
      901 tctgctactt ttgtgctcaa tgggaccctg gccagttacc cttcagatca ctgccaggac
      961 aacatgtggc gctgtccccg ccaagtgtcc actgtggtgt gtgtgcatga accgcgctgc
     1021 cagccacccg actgcagtgg ccatgggacc tgtgtggatg gccactgtga atgcaccagc
     1081 cacttctggc ggggcgaggc ctgcagcgag ctggactgtg gcccctccaa ctgcagccag
     1141 catgggctgt gcacagagac tggctgccac tgtgatgctg ggtggacagg atccaactgc
     1201 agtgaagagt gtcctctggg ctggtatggg ccaggttgcc agaggccctg ccagtgtgag
     1261 caccagtgtt cctgtgaccc gcagactggc aactgcagca tctcccaagt gaggcagtgt
     1321 ctccagccaa ctgaggctac gccgagggca ggagagctgg cctctttcac caggaccacc
     1381 tggctagccc tcaccctgac actaattttc ctgctgctga tcagcactgg ggtcaacgtg
     1441 tccttgttcc tgggctccag ggccgagagg aaccggcacc tcgacgggga ctatgtgtat
     1501 cacccactgc aggaggtgaa cggggaagcg ctgactgcag agaaggagca catggaggaa
     1561 actagcaacc ccttcaagga ctgaagagct gccccaacgg catgctccag ataatcttgt
     1621 ccctgctcct cacttccaca ggggacattg tgaggccact ggcatggatg ctatgcaccc
     1681 caccctttgc tggccatatt cctcctgtcc ccatgctgtg gctcatgcca acctagcaat
     1741 aaggagctct ggagagcctg cacctgcctc ccgctcgcct atatctgctg cccagaggcc
     1801 tgtctcgcac aggggtctcg ccactgccaa agactcccag gaagccacta gcaaatggaa
     1861 ctctgtaacc ccatcatgac aagagtggcc actctccgcc tgcacaggga tgaaatagaa
     1921 agccttacac acacacacac acacaccctc ggctcagcca cggcactcgc cttttataca
     1981 gcctcatcgc tggacagcca actagaactc tgcatcctgt cacaggaagc acctcataag
     2041 aagggatggg gagggaagga agtcgccttg tttacagacc tatttttgtt gtcttgttcc
     2101 ctaaaggagt tttctaacac ttgaataaat tgggatacta aaacaagcca cc
//
