LOCUS       NM_019750               1499 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus N(alpha)-acetyltransferase 80, NatH catalytic subunit
            (Naa80), mRNA.
ACCESSION   NM_019750
VERSION     NM_019750.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1499)
  AUTHORS   Drazic,A., Timmerman,E., Kajan,U., Marie,M., Varland,S., Impens,F.,
            Gevaert,K. and Arnesen,T.
  TITLE     The Final Maturation State of beta-actin Involves N-terminal
            Acetylation by NAA80, not N-terminal Arginylation by ATE1
  JOURNAL   J Mol Biol 434 (2), 167397 (2022)
   PUBMED   34896361
  REMARK    GeneRIF: The Final Maturation State of beta-actin Involves
            N-terminal Acetylation by NAA80, not N-terminal Arginylation by
            ATE1.
REFERENCE   2  (bases 1 to 1499)
  AUTHORS   Jadin,L., Wu,X., Ding,H., Frost,G.I., Onclinx,C., Triggs-Raine,B.
            and Flamion,B.
  TITLE     Skeletal and hematological anomalies in HYAL2-deficient mice: a
            second type of mucopolysaccharidosis IX?
  JOURNAL   FASEB J 22 (12), 4316-4326 (2008)
   PUBMED   18772348
REFERENCE   3  (bases 1 to 1499)
  AUTHORS   Shuttleworth,T.L., Wilson,M.D., Wicklow,B.A., Wilkins,J.A. and
            Triggs-Raine,B.L.
  TITLE     Characterization of the murine hyaluronidase gene region reveals
            complex organization and cotranscription of Hyal1 with downstream
            genes, Fus2 and Hyal3
  JOURNAL   J Biol Chem 277 (25), 23008-23018 (2002)
   PUBMED   11929860
  REMARK    GeneRIF: Characterization of the murine hyaluronidase gene region
            reveals complex organization and cotranscription of Hyal1 with
            downstream genes, Fus2 and Hyal3.
REFERENCE   4  (bases 1 to 1499)
  AUTHORS   Lerman,M.I. and Minna,J.D.
  TITLE     The 630-kb lung cancer homozygous deletion region on human
            chromosome 3p21.3: identification and evaluation of the resident
            candidate tumor suppressor genes. The International Lung Cancer
            Chromosome 3p21.3 Tumor Suppressor Gene Consortium
  JOURNAL   Cancer Res 60 (21), 6116-6133 (2000)
   PUBMED   11085536
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY203919.1 and AK137391.1.
            
            On Sep 13, 2016 this sequence version replaced NM_019750.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK137391.1, AF172275.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               BY203919.1         1-137
            138-1499            AK137391.1         3-1364
FEATURES             Location/Qualifiers
     source          1..1499
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 58.18 cM"
     gene            1..1499
                     /gene="Naa80"
                     /gene_synonym="Fus2; Nat6"
                     /note="N(alpha)-acetyltransferase 80, NatH catalytic
                     subunit"
                     /db_xref="GeneID:56441"
                     /db_xref="MGI:MGI:1888902"
     exon            1..267
                     /gene="Naa80"
                     /gene_synonym="Fus2; Nat6"
                     /inference="alignment:Splign:2.1.0"
     exon            268..1499
                     /gene="Naa80"
                     /gene_synonym="Fus2; Nat6"
                     /inference="alignment:Splign:2.1.0"
     CDS             359..1303
                     /gene="Naa80"
                     /gene_synonym="Fus2; Nat6"
                     /note="protein fus-2; N-acetyltransferase 6; protein
                     fusion-2 homolog"
                     /codon_start=1
                     /product="N-alpha-acetyltransferase 80"
                     /protein_id="NP_062724.1"
                     /db_xref="CCDS:CCDS23498.1"
                     /db_xref="GeneID:56441"
                     /db_xref="MGI:MGI:1888902"
                     /translation="MELILSTSPAKLTLDPARQPELTLRFNLSKLTLDPARQPELSLS
                     PRLAELTLDPTCHPEMSLSPGPAELTLDPQHQAKELPVPKLPELILEPVHCRPELMSA
                     CADLINDQWPRSRASRLHSLGQSSDAFPLCLMLLSPQPTPGAAPVVVGHARLSRVLDQ
                     PHSLLVETVVVARPLRGRGFGRRLMEGLEAFARARGFRRLHLTTHDQLYFYAHLGYQL
                     GEPVQGLAFTNRRLSTTVLRAFSKPPCPQPPCKEPILAAQAVPRSSKGPPLPPPPPLP
                     QSLTASPPPSPEPLPQSPLETCYRDLKGCPIFWMEKDI"
     regulatory      1479..1484
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Naa80"
                     /gene_synonym="Fus2; Nat6"
                     /note="hexamer: AATAAA"
     polyA_site      1499
                     /gene="Naa80"
                     /gene_synonym="Fus2; Nat6"
                     /note="major polyA site"
ORIGIN      
        1 accggaaggg aagaagccag ggacagaatg ggcctacagg agttctgttg tgacgctcag
       61 aaccaggggc ggggtgtcta ggtagggacg ttccgggcgg gcactgagaa cttaggagga
      121 ggtgctctgt ctcctgcgaa gactgcagtg agtcctccgt actgctggga ccagcgtagg
      181 cagaccgagg agttggagcc agagacagcg agttacccga ccgagcgcag gcaggacgtg
      241 gatcatcccg gaattcggct ttaacatcta gctgagcctg gattccacct gtaggccgga
      301 gctgactctg agccctggcc cagtcaagct gacccctacc ttagaccccg tgcaccggat
      361 ggagctgatc ctgagtacca gcccagcaaa gctgactcta gatcctgcac gccagccaga
      421 gttgaccctg agattcaacc tgtccaagct aaccctggat cctgcacgcc agccagagct
      481 gtcgctgagt cctaggctag ctgagctgac cctggatccc acatgccacc cagagatgag
      541 cctcagtcct ggcccagctg agcttaccct ggatcctcaa caccaggcaa aggagctccc
      601 agttcccaag ctgcctgaat taatcctgga gcctgtacac tgccgacccg agctcatgag
      661 tgcctgtgct gatctcatca atgaccagtg gccccgcagt cgtgcctccc gtctccactc
      721 cctgggccag tcctcagatg ccttccccct ctgcctgatg ctgctgagcc cccaacccac
      781 acctggagca gcccctgttg tggtgggcca tgcccgctta tcacgggtac tagaccaacc
      841 ccacagcctc ttagtagaga cagtggtggt agcccggcct ctgaggggcc gtggctttgg
      901 tcgccgcctc atggaaggct tggaggcctt tgccagagcc cggggtttcc gacggctaca
      961 cctcaccact catgaccagc tgtacttcta tgcccatctg ggctaccaac tgggtgagcc
     1021 tgtgcagggt ttggccttca ccaaccgtcg actgtccacc actgtcctac gtgccttctc
     1081 taagccaccc tgcccccagc caccctgcaa ggagcctatc ctagctgccc aagctgtccc
     1141 aaggagctcc aagggacccc cattgccacc acctcctccc ctaccccagt ctctgaccgc
     1201 ctcaccgcct ccttcacccg agccccttcc tcaaagccca ctagagacat gctatcgaga
     1261 tctgaagggg tgccctatat tctggatgga aaaagacatc tgatggctct gtctctctgg
     1321 gacactggat tgcccagaac agagccagcc tcagcccaca ggccatactt cagcccccac
     1381 aaccccctgt ggacaacctt accctgtgta tctttcatgg gtcccagcag gccagggggt
     1441 ggctttggag ctctggctca gagctgtcag tgtggctgaa taaaggcttc cattaggta
//
