LOCUS       NM_027643               3275 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus N(alpha)-acetyltransferase 40, NatD catalytic subunit
            (Naa40), mRNA.
ACCESSION   NM_027643 XM_001473047 XM_001473067 XM_912399 XM_922382
VERSION     NM_027643.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3275)
  AUTHORS   Charidemou,E., Tsiarli,M.A., Theophanous,A., Yilmaz,V.,
            Pitsouli,C., Strati,K., Griffin,J.L. and Kirmizis,A.
  TITLE     Histone acetyltransferase NAA40 modulates acetyl-CoA levels and
            lipid synthesis
  JOURNAL   BMC Biol 20 (1), 22 (2022)
   PUBMED   35057804
  REMARK    GeneRIF: Histone acetyltransferase NAA40 modulates acetyl-CoA
            levels and lipid synthesis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3275)
  AUTHORS   Liu,Y., Zhou,D., Zhang,F., Tu,Y., Xia,Y., Wang,H., Zhou,B.,
            Zhang,Y., Wu,J., Gao,X., He,Z. and Zhai,Q.
  TITLE     Liver Patt1 deficiency protects male mice from age-associated but
            not high-fat diet-induced hepatic steatosis
  JOURNAL   J Lipid Res 53 (3), 358-367 (2012)
   PUBMED   22231784
REFERENCE   3  (bases 1 to 3275)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY107005.1, AK033510.1, AK033896.1 and BB112808.2.
            
            On or before Jul 24, 2009 this sequence version replaced
            XM_912399.2, XM_922382.2, XM_001473047.1, XM_001473067.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK170548.1, AK033510.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               BY107005.1         2-178
            178-308             AK033510.1         2-132
            309-1832            AK033896.1         140-1663
            1833-3268           AK033510.1         1655-3090
            3269-3275           BB112808.2         665-671
FEATURES             Location/Qualifiers
     source          1..3275
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.29 cM"
     gene            1..3275
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /note="N(alpha)-acetyltransferase 40, NatD catalytic
                     subunit"
                     /db_xref="GeneID:70999"
                     /db_xref="MGI:MGI:1918249"
     exon            1..285
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     CDS             280..993
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /EC_number="2.3.1.257"
                     /note="N-acetyltransferase 11; Nalpha acetyltransferase
                     40; natD catalytic subunit; N(alpha)-acetyltransferase 40,
                     NatD catalytic subunit, homolog; N-alpha-acetyltransferase
                     D; protein acetyltransferase 1"
                     /codon_start=1
                     /product="N-alpha-acetyltransferase 40"
                     /protein_id="NP_081919.1"
                     /db_xref="CCDS:CCDS50377.1"
                     /db_xref="GeneID:70999"
                     /db_xref="MGI:MGI:1918249"
                     /translation="MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPV
                     FKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMT
                     DDRAWYLIAWENSSIPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQ
                     LMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRT
                     KFGDSQHSHTGGHCGGCCH"
     exon            286..381
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     exon            382..434
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     exon            435..530
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     exon            531..689
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     exon            690..773
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     exon            774..851
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     exon            852..3275
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3250..3255
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /note="hexamer: AATAAA"
     polyA_site      3270
                     /gene="Naa40"
                     /gene_synonym="4931433E08Rik; Nat11; NatD"
                     /note="major polyA site"
ORIGIN      
        1 attcctagcg cgacgctctg ccgcgcctcc cgcctttctg ttctcaggcc ttccgcgcgc
       61 acggcaaccg ttccacctgc gcgccttcgc gctcgccgcc cactctggtc cggttctgcg
      121 ccggcgcggg gccctctagg acgcgcgggg gatttgtgag acgcatgcgt agtgcgcggc
      181 cggccgcttc gctgtcgctc gggttccgcc gttgccacct ccctacgggc aagtgcgaga
      241 ggggagccga gggccgccgc cgtcgccgcc gccgccacca tggggagaaa gtcgagcaaa
      301 gccaaagaga agaagcagaa acgattggag gagagagcgg ccatggatgc tgtgtgtgcc
      361 aaagtggatg ctgccaacag gcttggagac cctctggagg cattcccagt cttcaagaag
      421 tatgaccgca atgggttgaa tgtctccatt gaatgtaagc gagtgtctgg attggagcca
      481 gccactgtgg actgggcctt cgacctgacc aaaaccaata tgcagacgat gtatgagcaa
      541 agtgagtggg gctggaagga ccgagaaaaa cgggaggaaa tgaccgatga ccgagcctgg
      601 tacctcattg cttgggaaaa cagttccatc ccagttgcct tttctcactt ccggtttgat
      661 gtggagtgcg gggatgaagt cctgtactgc tatgaagtgc agctggaaag caaggtacgg
      721 cggaaaggcc tagggaagtt cctcattcag atcctgcagc tcatggccaa cagcacacag
      781 atgaagaagg tgatgttaac tgtttttaaa cataatcatg gcgcctatca gttcttccga
      841 gaggcactgc agtttgaaat tgatgactct tcacccagca tgtctggttg ctgtggggag
      901 gactgttcct atgagattct gagccggagg accaagttcg gggacagtca gcactcccac
      961 acaggcggcc actgtggtgg ctgttgccac tgaactccta gaaccacttt gaagggatgt
     1021 cactctcctt aggcctgtcc cctccctggt cttatgccac ttgccaggta ccctcagagc
     1081 tgtggggtgc cttagttctg cgtgagccag gcatatcctg agaacacaga accttgggga
     1141 gcagtgaccc cagctgcctt tccacctccc tcctggaaaa gcagagtgcc aggagggagc
     1201 accgaggaga gggtgccgtg agattgacag gttggctgtc aagctcatcc ttgtgcagta
     1261 gctgcctact tacttagttc ttgggcccct aaaatggaag gcttccctct tgtctgcagc
     1321 tgagttcctg accgggttgc acaccatgcc ccatatggac aaatggaatg ttgttaatac
     1381 ccacgtttgt aaaaggcctg gagtctgctg gtccccagaa agaactggat gcaaatctgg
     1441 gcatacaaca gaccttggac atcttttctc tggggacaaa gtgctctttc agagaccatg
     1501 tagcccttga tgtcaaggtg caaaggtttg cactgtaatc ttatagatcc acaggtggtg
     1561 tctcgggacc agccaacttc aggagggagt ctgcctccac cactgtcagt aagacaggat
     1621 caggaagagc tgtctcttac gtgtttgtca tagggatgtg gcatctctgg gcctttggac
     1681 tttgctgcat tttcatgatc ttgacttgac ctttttattc aagaaggaag tcaaagtcct
     1741 gcctgttctc acacctctct tctcagccca gatacctctg ttcttagtct caaggggaac
     1801 aacatcaggg agcctctcgt cttccccaga agaacccttc cttcctggta tagctgaatc
     1861 catttcttcc tattcttggt gctgatagct ctctgaaggt ggggtacttc cctgccaccc
     1921 tccctgactg aggggcccca gccagcagca ggcccctttg cctgttctcc cgagccccac
     1981 ccctcaccgc ctcaatgagg cactcgtgcc actgtcttgg cacccctggg atgcctttca
     2041 gtggcgtacc actgctttcc tgtcatgggt gtcaccctac agtgacaggc tagagccaga
     2101 aggccttcct cctcagggga tacaggctta gaacttgaac tcgccctgac ctctggatcc
     2161 tgttcttcaa ggaagcaaaa ccaaatcctt acctagaaaa acagacttgc cacttcccca
     2221 ttgctgcccc tgagttccgc cttgggaggc gtggcagaga gcttgccttt gtgcagttgc
     2281 tttcagagac tctgctaccg agctgagtct gttcacctta cccagcctga ctcagctgtc
     2341 tgttctggca agtctcccca aaggagtcac ctctcgccca gatccttggc ttgtgcagta
     2401 gcctggactc agagagtcct ttcttgcttg gtctgtccgc tgttgaacac tctgtgctgt
     2461 tgttagccct tggccttgcc tgggagaagg ccttgcagct ttacactgga ataggtctgc
     2521 ttttgtctgg cttgctagct tctgggctat acctctggtg agagttggag ctgcccagaa
     2581 gggattggca tgctccttcc gagaatcatg agacaggagc atgcttgcag gagttattcc
     2641 ctaatctctg tctgtcttag atcatgaatc tctgatacct cctacttagg ggtccagaag
     2701 gaacccccag tgtaagcccc atgtaaggtg aatagagtgt ctcgtctcca gttactggac
     2761 acccagcacc aggactcatg gtgctcagtg cctgccctgc tccccaccct ctgcaggccc
     2821 catcccaaag ggcccttcag gatctctcac tggaccagcg ggatggtggc caagaccagc
     2881 agattactcc tgtgggtgtt aagcccagtg gttcatcagg catcgtctac cgccctcttg
     2941 ttttgagaaa cagcaggtct aatctactgt accaggctct tttgcttttt gttccaggag
     3001 tgttaaaatg gttttaaaag ttttcgtttt gttttagtga acctattcca tttcaggtta
     3061 tttttgttgc tgttaaatgt ttatggttct ttttaacctt ttctggaggg ttggggggtt
     3121 atttttgttt ttaagaggaa agttggaagg taattttgtt ttatattttt tttcctagca
     3181 gttcattatc actggaatca aagggaaaaa aaccatctct ctttgtatcc attttatttg
     3241 tatgtcatta ataaacagat actttgtgca gatgc
//
