LOCUS       NM_001093775            7198 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus myelin transcription factor 1-like (Myt1l), transcript
            variant 1, mRNA.
ACCESSION   NM_001093775
VERSION     NM_001093775.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7198)
  AUTHORS   Nagai,M., Porter,R.S., Miyasato,M., Wang,A., Gavilan,C.M.,
            Hughes,E.D., Wu,M.C., Saunders,T.L. and Iwase,S.
  TITLE     Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A,
            prevents excessive synaptogenesis
  JOURNAL   J Biol Chem 300 (11), 107881 (2024)
   PUBMED   39395799
REFERENCE   2  (bases 1 to 7198)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7198)
  AUTHORS   Puelles,L. and Hidalgo-Sanchez,M.
  TITLE     The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic
            Organizer
  JOURNAL   Int J Mol Sci 24 (11), 9769 (2023)
   PUBMED   37298722
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7198)
  AUTHORS   Weigel,B., Tegethoff,J.F., Grieder,S.D., Lim,B., Nagarajan,B.,
            Liu,Y.C., Truberg,J., Papageorgiou,D., Adrian-Segarra,J.M.,
            Schmidt,L.K., Kaspar,J., Poisel,E., Heinzelmann,E., Saraswat,M.,
            Christ,M., Arnold,C., Ibarra,I.L., Campos,J., Krijgsveld,J.,
            Monyer,H., Zaugg,J.B., Acuna,C. and Mall,M.
  TITLE     MYT1L haploinsufficiency in human neurons and mice causes
            autism-associated phenotypes that can be reversed by genetic and
            pharmacologic intervention
  JOURNAL   Mol Psychiatry 28 (5), 2122-2135 (2023)
   PUBMED   36782060
  REMARK    GeneRIF: MYT1L haploinsufficiency in human neurons and mice causes
            autism-associated phenotypes that can be reversed by genetic and
            pharmacologic intervention.
REFERENCE   5  (bases 1 to 7198)
  AUTHORS   Chen,J., Fuhler,N.A., Noguchi,K.K. and Dougherty,J.D.
  TITLE     MYT1L is required for suppressing earlier neuronal development
            programs in the adult mouse brain
  JOURNAL   Genome Res 33 (4), 541-556 (2023)
   PUBMED   37100461
  REMARK    GeneRIF: MYT1L is required for suppressing earlier neuronal
            development programs in the adult mouse brain.
REFERENCE   6  (bases 1 to 7198)
  AUTHORS   Weiner,J.A., Hecht,J.H. and Chun,J.
  TITLE     Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed
            by mature oligodendrocytes during myelination in the postnatal
            murine brain
  JOURNAL   J Comp Neurol 398 (4), 587-598 (1998)
   PUBMED   9717712
REFERENCE   7  (bases 1 to 7198)
  AUTHORS   Yamazaki,K., Mizui,Y., Sagane,K. and Tanaka,I.
  TITLE     Genetic mapping of mouse tumor necrosis factor-alpha converting
            enzyme (TACE) to chromosome 12
  JOURNAL   Genomics 49 (2), 336-337 (1998)
   PUBMED   9598327
REFERENCE   8  (bases 1 to 7198)
  AUTHORS   Kim,J.G., Armstrong,R.C., v Agoston,D., Robinsky,A., Wiese,C.,
            Nagle,J. and Hudson,L.D.
  TITLE     Myelin transcription factor 1 (Myt1) of the oligodendrocyte
            lineage, along with a closely related CCHC zinc finger, is
            expressed in developing neurons in the mammalian central nervous
            system
  JOURNAL   J Neurosci Res 50 (2), 272-290 (1997)
   PUBMED   9373037
REFERENCE   9  (bases 1 to 7198)
  AUTHORS   Weiner,J.A. and Chun,J.
  TITLE     Png-1, a nervous system-specific zinc finger gene, identifies
            regions containing postmitotic neurons during mammalian embryonic
            development
  JOURNAL   J Comp Neurol 381 (2), 130-142 (1997)
   PUBMED   9130664
REFERENCE   10 (bases 1 to 7198)
  AUTHORS   Jiang,Y., Yu,V.C., Buchholz,F., O'Connell,S., Rhodes,S.J.,
            Candeloro,C., Xia,Y.R., Lusis,A.J. and Rosenfeld,M.G.
  TITLE     A novel family of Cys-Cys, His-Cys zinc finger transcription
            factors expressed in developing nervous system and pituitary gland
  JOURNAL   J Biol Chem 271 (18), 10723-10730 (1996)
   PUBMED   8631881
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB521730.1, BE653129.1, BC094438.1, CD802997.1, BQ876229.1,
            CX240996.1 and AK013654.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U86338.1, SRR9219379.29497.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-426               CB521730.1         1-426
            427-763             BE653129.1         1-337
            764-1938            BC094438.1         1-1175
            1939-2560           CD802997.1         1-622
            2561-3109           BC094438.1         1792-2340
            3110-3540           BQ876229.1         238-668
            3541-6049           BC094438.1         2772-5280
            6050-6517           CX240996.1         49-516
            6518-7198           AK013654.1         219-899
FEATURES             Location/Qualifiers
     source          1..7198
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 11.86 cM"
     gene            1..7198
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /note="myelin transcription factor 1-like"
                     /db_xref="GeneID:17933"
                     /db_xref="MGI:MGI:1100511"
     exon            1..413
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            414..509
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            510..616
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            617..752
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            753..906
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             907..4470
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     myelin transcription factor 1-like protein; neural zinc
                     finger protein NZF-1; myT1-L; neural zinc finger factor 1;
                     postmitotic neural gene 1 protein; neural zinc finger
                     transcription factor 1; postmeiotic neural gene 1; zinc
                     finger protein Png-1"
                     /codon_start=1
                     /product="myelin transcription factor 1-like protein
                     isoform 1"
                     /protein_id="NP_001087244.1"
                     /db_xref="CCDS:CCDS49042.1"
                     /db_xref="GeneID:17933"
                     /db_xref="MGI:MGI:1100511"
                     /translation="MDVDSEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSG
                     KYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECYESDGTEDMDDK
                     EEDDDEEFSEDNDEQGDDDDEDEVDREDEEEIEEEDDEEDDDDEDGDDVEEEEEDDDE
                     EEEEEEEEEENEDHQMSCTRIMQDTDKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAY
                     RARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVV
                     LSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQ
                     CFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSP
                     RSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMR
                     EKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYGKDPSRTEKRESKCP
                     TPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNR
                     NSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRN
                     NVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRY
                     CKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNL
                     STRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMS
                     PQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDEPKEITPEDLDPFQEALEERR
                     YPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGS
                     GHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYAS
                     HRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLS
                     GCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMI
                     KLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINE
                     QNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV"
     exon            907..961
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..995
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1058
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1420
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..2392
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2393..2527
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2528..2618
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2726
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2727..2941
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2942..3192
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3193..3429
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3430..3551
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3552..3620
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3621..3683
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3684..3767
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3768..3989
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3990..4081
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4185
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4186..4329
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4330..7198
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7163..7168
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
     polyA_site      7198
                     /gene="Myt1l"
                     /gene_synonym="2900046C06Rik; 2900093J19Rik;
                     C630034G21Rik; mKIAA1106; Nztf1; Pmng1; Png-1"
ORIGIN      
        1 gtggagctgc gtgcattagg ggctggctgt ggaggtaaag cagatctctt aggcccgcta
       61 gcctctcctg ctgcatgtgt cattcctgcc cgcgcgacat tttcccccta agctactgca
      121 cacaaaacag agcgagaaag cttctccctg cagtcttctt ggaggcctcc tggtttctca
      181 cccattgttg gtgggtgtat ttcaattttt tgattccctg gactgtgggt tatgaaatca
      241 atgctgctga agacaaaagc aaccttccct gcctctcggt gctatgcgtg gtcctcctcg
      301 gcctcccact tgtgggggaa agggttttct ctttctttct gtgtgttttg agccagcaca
      361 gttaccaaaa ttgaacttgc cgtcacttgt gagcggtgtg gtcatggtgt gaggggtccc
      421 acagaggctg cagctgaggt ctgggtgtgt gcaattctca gctgggcttt gccctaccca
      481 ggttgacgac tgaagaatca cagagtgtgg aaaagaacac aaggagaaat tggtgagaac
      541 atctgcctag catctccaag tcctgtggag ggagccagca gtgctggtcc aaagaggacc
      601 cagagagtga actcagagtg accacatctg atagaagagg ggaagatgta gtttctgagt
      661 ccagtccagt gtttgtgtct ctcacattgt caacaaaaga aaggctccag ctgtccccac
      721 agacatatgg atattccagg agccacgtaa agatggagaa atggaggcac agagaaatta
      781 agtgacttgg ccacagtcac aagctgggga ggaccaggga aagcctagag agagctggct
      841 ctgggcctgc atcctgccca cggagtcacc ctgcctccgt cctcaggaga gaaggcttcc
      901 tacaagatgg acgtggactc tgaggagaag cgccatcgca cacggtccaa aggggttcga
      961 gttcctgtgg agccagccat acaagagctg ttcagctgtc ccactccagg ctgcgacggc
     1021 agtggtcacg tcagtggcaa atatgcacga cacagaagtg tatatggttg tcccttggct
     1081 aaaaaaagaa aaacgcaaga taaacagccc caagaacctg ctcccaagcg aaaaccattt
     1141 gcagtaaaag cagatagttc ctcagtagac gaatgttatg agagtgatgg tactgaagac
     1201 atggatgata aggaggaaga tgatgatgag gagttctctg aagacaatga tgagcaaggg
     1261 gatgatgacg acgaagatga ggtggatcgg gaagacgagg aggagatcga ggaggaagat
     1321 gatgaagaag atgatgatga tgaagatggt gacgatgtag aagaggaaga agaggatgat
     1381 gatgaagagg aggaagaaga ggaagaggaa gaagaaaatg aagaccatca aatgagttgt
     1441 actcgaataa tgcaggacac agacaaggat gataacaaca atgatgagta tgataactat
     1501 gatgaactgg tagctaagtc gctattaaat cttggcaaaa ttgctgagga tgcagcatac
     1561 cgagccagga ctgaatcaga gatgaacagc aatacctcca atagtctgga ggacgatagt
     1621 gacaaaaacg aaaacctcgg tcggaaaagc gaactgagtc tagacttaga cagtgatgtt
     1681 gttagagaaa cagtggactc ccttaagctg ttagcacaag gacatggtgt tgtgctatca
     1741 gagaatatca gtgacagaag ttatgctgag gggatgtcac agcaggacag tagaaatatg
     1801 aactatgtca tgctagggaa gcccatgaac aatggactca tggagaagat ggtggaggag
     1861 agtgatgagg aagtgtgtct aagtagtcta gagtgcctga ggaaccagtg ctttgacctg
     1921 gccaggaaac tcagcgagac caacccacag gacaggagtc agccacccaa catgagtgtg
     1981 cgccaacatg tccggcaaga ggacgacttc cctgggagga cgccagacag gagctactcg
     2041 gatatgatga accttatgcg gctggaggag cagctcagtc ccaggtctag aacgttctcc
     2101 agctgtgcca aggaggatgg gtgtcatgag agggatgatg acaccacctc agtgaactca
     2161 gacaggtctg aggaagtgtt tgacatgacc aagggcaacc tgactctgct agagaaagcc
     2221 attgccttgg agacagagag agccaaggcc atgcgggaga agatggccat ggatgctggg
     2281 agaagggata acctgagatc ctatgaggac cagtctccaa gacagctggc tggggaagac
     2341 agaaaatcca aatccagtga cagccatgtc aaaaagccat actatggtaa agatccctca
     2401 agaacagaaa agagagagag caagtgtcca acccccgggt gtgatggaac cggccacgta
     2461 actgggcttt acccgcatca ccgcagtctg tctggatgcc cgcacaaaga tagggtccct
     2521 ccagaaattc ttgccatgca tgaaaatgtt ctcaagtgtc ccactccagg ctgcacaggg
     2581 cgagggcatg tgaatagcaa caggaactcg cacagaagcc tctctggatg ccccattgct
     2641 gctgcagaaa aactggcaaa ggcccaagag aaacaccaga gctgtgatgt gtccaaatcc
     2701 aaccaggcct cagaccgagt cctcaggcca atgtgctttg tcaaacagct tgagattcct
     2761 cagtatggct acagaaacaa tgttcccaca accacaccac gctccaacct ggccaaggag
     2821 cttgagaaat actccaagac ttcgtttgag tacaacagtt acgacaacca tacttatggc
     2881 aaaagagcca tagctcccaa ggtgcaaacc agggacatat cccccaaagg atatgacgat
     2941 gccaagcggt actgcaagaa tgccagcccc agcagcagca ccaccagcag ctatgcacct
     3001 agcagcagca gcaacctcag ctgtggtggt ggcagcagcg ccagtagcac gtgtagcaag
     3061 agcagctttg actacacaca tgacatggag gccgcacaca tggcagccac agccattctc
     3121 aacctgtcca cacgttgtcg tgaaatgcca cagaacctgt ccaccaagcc acaggacctg
     3181 tgtactgccc ggaacccaga catggaggtg gatgagaatg gcaccctgga cctgagcatg
     3241 aacaagcaga ggcctcgaga cagctgctgc ccagtcctga cacccctgga acccatgtct
     3301 ccgcagcagc aggccgtgat gagcagccga tgcttccagc tgagcgaggg ggattgctgg
     3361 gacttgcctg tagactacac caaaatgaag cctcggaggg tagatgagga tgagcccaaa
     3421 gagattaccc cagaagactt ggacccattc caggaggctc tggaagaaag acggtatcca
     3481 ggggaggtga ccatcccaag ccccaaaccc aagtaccctc agtgcaagga aagcaaaaag
     3541 gacttaataa ctctgtctgg ctgccccctg gcggacaaaa gcattcgaag tatgctggcc
     3601 accagttccc aagagctcaa gtgccccacc cctggctgtg acggttctgg acacatcact
     3661 ggcaattacg cttctcatcg aagcctttct gggtgcccga gagcaaagaa gagtggcatc
     3721 cggatagcac agagcaaaga ggacaaggaa gaccaggagc caatcaggtg tccggtacct
     3781 ggctgtgacg gtcagggaca catcactggg aagtatgcat cccaccgcag cgcctccggg
     3841 tgtcccttgg cagccaagag gcagaaagat gggtacctta atggctccca gttctcctgg
     3901 aagtcggtca agacggaggg catgtcctgc cctacccccg ggtgtgatgg gtcaggacac
     3961 gtcagtggca gcttcctcac acaccgcagc ttgtcaggat gtccaagagc cacatcagca
     4021 atgaagaaag caaagctgtc tggagaacag atgttgacta tcaagcagcg agccagcaac
     4081 ggtatagaaa atgatgaaga aatcaagcag ttagatgaag agatcaagga gcttaatgag
     4141 tccaattccc agatggaggc tgacatgatc aaactcagaa ctcagatcac cacaatggag
     4201 agcaacctga agacgattga ggaggagaac aaagtcattg aacagcagaa tgagtcgctc
     4261 ttgcacgagt tggccaacct gagccagtcc ctgatccaca gcctcgccaa catccagctg
     4321 cctcacatgg atccaatcaa tgaacaaaat tttgatgctt acgtgactac tttgacggaa
     4381 atgtatacaa atcaagatcg ttatcagagt ccagaaaata aagccctact ggaaaatata
     4441 aagcaggctg tgagaggaat tcaggtctga acagctgctc tagtggtgac tcatgcttaa
     4501 aaaggatgcc tcttgtttct tgctgctgta acttaccaga aagtgttata tatttatttc
     4561 tgtcggaaca gtgttatgct acaagacttc ataatggttt tgtgtgctct cgagagagta
     4621 cctgcagact agttttggat acattcacat tttgtacgtt ttcatataag ctgacatagt
     4681 gtgatttgcc atgtaatgtt tatagctgct gctgtctgca catttggggg tctctatatt
     4741 tctgaagagg taagctgatg aaaataaata gagtgtaaat tctttttaat gctttagtga
     4801 ttaaatgttt tagtattttg aactgaaatg gacaaaaaaa gaaaaaggaa aaaaaaagca
     4861 ggtttgaacg atcactttgt ggcctcctgg ccacttttag acattatcat tttgcctcag
     4921 gttggaggac tttgtggaat ttaagaaata cattttgtgt gcatattgtt tcatagcaag
     4981 aattggttgc aaaaaaatgc tttatttttg aacaatgctt ggaaatatta tgtgactttt
     5041 ttgtttgttt gttttaggag gatggtgtat ggtgggggca ataaatgagg ttttttgcat
     5101 tccaaggaaa tggcatatgg attaactata agaaatgaaa taagtaattt attgtaagac
     5161 aacatcaagc catggaaact tggcagaaga ttcaaagcag cttaaacagc acttttaatt
     5221 aactcctaaa cattacatgg tgggactgtg gagactccgt taagacagga gcttgtcaga
     5281 ggtggacaac acgaagattt cctttgcatt ttcagtaacc tttggagcac acttctctta
     5341 tttctcctag agccccgtgc ccctctgaag tgttaccaca atctagctta cctagcagcc
     5401 gttgattgtt ttttttccat ctgagcaaac aggtaattta agcatttatc tcccctttca
     5461 ctttcaaaaa gaatcatcat tgattattct tgtttcacat ctgaggatga aggctaacgg
     5521 ctgtgcttgc cctggttact ggatgggatt ctctgctggg cgggtgggga agcagctcta
     5581 cccttcccta cccctccctg ccccaactct gacttcgaat aagccttggt cctatccaga
     5641 atacactgga caccaaggcc aaggacgttc acgttctgcc ctcgctgggt ccagctgact
     5701 ctagcgtctg cacagccttg tgtgactcgt ggtgacctaa cctgagaaag agtgcaatca
     5761 gatgttaaag taactaaata gactgcggca cttttttgct ttaaactaga tcatcttaga
     5821 tttgtcgata ccttcgaaat ttgatggttt catcccaaat gactgcacta tatgtatgca
     5881 tacggccact tttgattgct gcgccccttc tgagtagtct ttgacaatgt gttgtgttcc
     5941 ccgatgtcga cttgatttcc ttttagtagc atctctctct tccatgtctt gatgttatgc
     6001 aggaagtaca aaagtacttt aaaattttgt tatgaaataa aaaaaaaaag gatgggtttt
     6061 gtaaaaataa taaaaaaaat atttttagca gaacaggact tacagggtca ttgtccccac
     6121 aatgtgccag tcggctcttt gcactcgcct tgtcctatat atccgtacgg aggtgtgcaa
     6181 tcctgtgtca gtcgccttgt gacactgaag tggatgagtt atagaggagg ccctcgaggc
     6241 tgacccaata cggttactaa gggagactac agggatctca cgacaaacat tctgatacaa
     6301 tactcaacct cggtatatat atatatatat atatatatat acatatatat atatgtataa
     6361 atataagaat atcccagcgg cactttatac tgttcactgt acaaaagctt acagttttcc
     6421 acaaggactt taataactag ctggggaaaa gattatgtaa ttacttgggg ctctgcagga
     6481 ccttctctgt ccagcgcccc ctttctgttg tgcgattagt tgtagctgcc atgctcagaa
     6541 ttgccttttg agagctgaag caaggtgctt actgtcacct gatgccatac acatggtccc
     6601 aggcccacac ccggggggcc tctgttcata gcggcacatg catttcccca ccgcgtcttg
     6661 tctgcagctt cttggccaat gtagtaatgc ttttagtaga gtaataggta gtatcagttt
     6721 ggattcttat tgttatcacc tatgtacaat ggagaggggt tctaagcaca aatctgctgc
     6781 tcatgtaacg gtggtacata atatcaaatc aaaagttatc tgtgactata tatagggatc
     6841 acaaagtgtc acatgttaga atgctgacct tccacatggg gttattgtga gtcatcagag
     6901 catatttatt ataacttatt gttcatattc atttctaagt taatttaagt aatcatttat
     6961 taagacagaa ttttgtataa actatttatt gtgctctctg tggaactgaa gtttgattta
     7021 tttttgtact acacggcatg ggtttgttga cactttaatt ttgctataaa tgtgtggaat
     7081 cacaagttgc tgtgatactt catttttaaa ttgtgaactt tgtacaaact ttgtcatgct
     7141 gatgtgaaca catcttactc tgaataaaaa ggtgttgcca cgtttgtagc acgaagga
//
