LOCUS       NM_001085509            5578 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus myomesin family, member 3 (Myom3), mRNA.
ACCESSION   NM_001085509 XM_144099 XM_987631
VERSION     NM_001085509.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5578)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5578)
  AUTHORS   Gomez-Del Arco,P., Perdiguero,E., Yunes-Leites,P.S., Acin-Perez,R.,
            Zeini,M., Garcia-Gomez,A., Sreenivasan,K., Jimenez-Alcazar,M.,
            Segales,J., Lopez-Maderuelo,D., Ornes,B., Jimenez-Borreguero,L.J.,
            D'Amato,G., Enshell-Seijffers,D., Morgan,B., Georgopoulos,K.,
            Islam,A.B., Braun,T., de la Pompa,J.L., Kim,J., Enriquez,J.A.,
            Ballestar,E., Munoz-Canoves,P. and Redondo,J.M.
  TITLE     The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle
            Identity and Metabolic Homeostasis
  JOURNAL   Cell Metab 23 (5), 881-892 (2016)
   PUBMED   27166947
REFERENCE   3  (bases 1 to 5578)
  AUTHORS   Rouillon,J., Poupiot,J., Zocevic,A., Amor,F., Leger,T., Garcia,C.,
            Camadro,J.M., Wong,B., Pinilla,R., Cosette,J., Coenen-Stass,A.M.,
            Mcclorey,G., Roberts,T.C., Wood,M.J., Servais,L., Udd,B., Voit,T.,
            Richard,I. and Svinartchouk,F.
  TITLE     Serum proteomic profiling reveals fragments of MYOM3 as potential
            biomarkers for monitoring the outcome of therapeutic interventions
            in muscular dystrophies
  JOURNAL   Hum Mol Genet 24 (17), 4916-4932 (2015)
   PUBMED   26060189
  REMARK    GeneRIF: MYOM3 fragments hold promise for minimally invasive
            assessment of experimental therapies for DMD and other
            neuromuscular disorders.
REFERENCE   4  (bases 1 to 5578)
  AUTHORS   du Puy,L., Beqqali,A., van Tol,H.T., Monshouwer-Kloots,J.,
            Passier,R., Haagsman,H.P. and Roelen,B.A.
  TITLE     Sarcosin (Krp1) in skeletal muscle differentiation: gene expression
            profiling and knockdown experiments
  JOURNAL   Int J Dev Biol 56 (4), 301-309 (2012)
   PUBMED   22562206
REFERENCE   5  (bases 1 to 5578)
  AUTHORS   Beqqali,A., Monshouwer-Kloots,J., Monteiro,R., Welling,M.,
            Bakkers,J., Ehler,E., Verkleij,A., Mummery,C. and Passier,R.
  TITLE     CHAP is a newly identified Z-disc protein essential for heart and
            skeletal muscle function
  JOURNAL   J Cell Sci 123 (Pt 7), 1141-1150 (2010)
   PUBMED   20215401
REFERENCE   6  (bases 1 to 5578)
  AUTHORS   Schoenauer,R., Lange,S., Hirschy,A., Ehler,E., Perriard,J.C. and
            Agarkova,I.
  TITLE     Myomesin 3, a novel structural component of the M-band in striated
            muscle
  JOURNAL   J Mol Biol 376 (2), 338-351 (2008)
   PUBMED   18177667
  REMARK    GeneRIF: Myomesin 3, a novel structural component of the M-band in
            striated muscle.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662911.21.
            
            On Mar 9, 2013 this sequence version replaced NM_001085509.1.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data because no single transcript from the reference strain was
            available for the full length of the gene. The extent of this
            transcript is supported by orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.5278.1,
                                           SRR10223970.6886.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AL662911.21        104335-104426
            93-271              AL662911.21        107122-107300
            272-352             AL662911.21        108263-108343
            353-512             AL662911.21        109409-109568
            513-670             AL662911.21        110164-110321
            671-766             AL662911.21        115291-115386
            767-855             AL662911.21        116152-116240
            856-900             AL662911.21        118385-118429
            901-1041            AL662911.21        118901-119041
            1042-1203           AL662911.21        120165-120326
            1204-1345           AL662911.21        120955-121096
            1346-1545           AL662911.21        122657-122856
            1546-1599           AL662911.21        123973-124026
            1600-1727           AL662911.21        124420-124547
            1728-1911           AL662911.21        127635-127818
            1912-2086           AL662911.21        130434-130608
            2087-2208           AL662911.21        132019-132140
            2209-2396           AL662911.21        132515-132702
            2397-2523           AL662911.21        132908-133034
            2524-2702           AL662911.21        134154-134332
            2703-2817           AL662911.21        139702-139816
            2818-2974           AL662911.21        140901-141057
            2975-3084           AL662911.21        141584-141693
            3085-3129           AL662911.21        142074-142118
            3130-3266           AL662911.21        142915-143051
            3267-3411           AL662911.21        145622-145766
            3412-3471           AL662911.21        145962-146021
            3472-3539           AL662911.21        146336-146403
            3540-3650           AL662911.21        147828-147938
            3651-3738           AL662911.21        150658-150745
            3739-3777           AL662911.21        151504-151542
            3778-3886           AL662911.21        151789-151897
            3887-4050           AL662911.21        153416-153579
            4051-4087           AL662911.21        155369-155405
            4088-4110           AL662911.21        155555-155577
            4111-4166           AL662911.21        157064-157119
            4167-5578           AL662911.21        158776-160187
FEATURES             Location/Qualifiers
     source          1..5578
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 68.0 cM"
     gene            1..5578
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /note="myomesin family, member 3"
                     /db_xref="GeneID:242702"
                     /db_xref="MGI:MGI:2685280"
     exon            1..92
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            93..271
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..4430
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /codon_start=1
                     /product="myomesin-3"
                     /protein_id="NP_001078978.1"
                     /db_xref="CCDS:CCDS38921.1"
                     /db_xref="GeneID:242702"
                     /db_xref="MGI:MGI:2685280"
                     /translation="MTLPHSPGSAGEPQASQTVQVHRLEHRQEEEQKEERQHSLQMGS
                     SVQRRTYRSSEEEQQFSSEDYALAAALALTASSELSWEAKLRRQTTTVELEERGQRRV
                     GFGNDLERMELAFLRTQRLLRQRRDWKALRQRTEEKVREAKELIELCSGRGPWFWIPL
                     RSHAVWEHTTVLLTCTVQGSPPFQVTWYKNDIRIDPRLFPAGKYRITNNYGLLTLEIM
                     RCTVEDSATYTVLVKNAYGQASSFAKVLIRNYLGKDAGFDSEIFKRSMFGPSAEFTSV
                     LKPIFAQEKEPFSLTCLFSDDVLEAEQRIQWYRDGRLLRSSTRRQILYADRQASVKVS
                     CAYKEDEGFYTIRVSSPFGPQEQSAYVFIRDAAAEKPGAPGSPLNVRCLNVHRDCLTL
                     TWVPPSDTRGSTITGYSIEMCQGDSEEWMPCLKAPGGTCRCPIQGLVEGQSYQFRVRA
                     ISKAGTSLPSKASEAVVTGDYDAVHKSTEIPYDLGSKITISKNDFEDAVTIPSAPTNV
                     HASEIREAYAVLSWEEPRPRGRAPLTYTLEKSVIGSGTWEAISTETPIKSPRFALLDL
                     EKGKSYVFRVRALNQYGMSDPSEPSEPVALKGKPATLPPPAQVQAFRNTQTSVSLAWE
                     PVDGGSELLGYYIYSREAGASEWQTVNNKPIQDTKFTVPGLRTGKEYDFCIRSVSEAG
                     VGESSAATQPVRVKQALATPSAPYDFALLNCGKNEMVIGWKPPKRRGGGKILGYFMDQ
                     HDSVESDWHPVNRQPIPSRVCKVTNLHEGHFYEFRARAVNWAGIGELSAPSSLFECKE
                     WTMPEPGPPYDVRVSEVQATSVMLQWEPPLYIGAGPVTGYHVSFQEKGSEEWKPVTPD
                     ATSDTHLRVSDLQPGKQYMFRVQAMNSAGLGQPSVPTDPVLLEDKPDAQEIEVGVDDE
                     GQIYLAFEAPEAPDFPEFQWSKDYQGPPDPQRVEVEDEISKSKVILKEPDLQDLGIYS
                     VVVPDADEDTSASHTLTEEELNKLKKLSHEIRNPVIKLISGWNVEILEQGEVRLWLEV
                     EKLSPAAELHLIFNEKEIFSSPNRKINFDREKGLVEVIIQQLSEDDKGSYTAQLQDGK
                     AKNQITLALVDDEFDKLLRKADAKRRDWKRKQGPYFQEPLTWKVTDDCQVLLSCKVTN
                     TKKESRFQWFFQKKEAPHGQYNPPTGDGSLSIEGFSKENQGVYRAVVSDERGEDDTVL
                     DLTGEALDAVLTELGRIGALSATPLKIQGTEEGIRLFSKVKYYNVDYMKTAWFHKDKR
                     LESGDRVRAGTTLDEIWLHILDPKDSDKGKYTLEITAGKEVRQLSADLSGQAFDDALA
                     EHQRLKALAVIEKNRAKVVRGLPDVATIMEDKTLCLTCVISGDPSPEISWLKNDQPIS
                     FFDRYHMEVKGTEVTVTIDKVTSEDSGRYGIFVKNKYGSETGQVTISVFKHGEEPKEL
                     KKK"
     exon            272..352
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            353..512
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            513..670
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            671..766
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            767..855
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            856..900
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1041
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1203
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1345
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1545
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1599
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1727
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..1911
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2086
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2208
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2209..2396
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2523
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2702
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2703..2817
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2818..2974
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3084
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3085..3129
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3130..3266
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3267..3411
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3412..3471
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3539
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3540..3650
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3651..3738
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3739..3777
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3778..3886
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            3887..4050
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            4051..4087
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            4088..4110
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            4111..4166
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     exon            4167..5578
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5542..5547
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /note="hexamer: AATAAA"
     polyA_site      5573
                     /gene="Myom3"
                     /gene_synonym="8430427K15Rik; Gm434"
                     /note="major polyA site"
ORIGIN      
        1 attcttcccc cgtcctcact gagccgagga caagaagaga gcagagagcc tcttactgtc
       61 ctagagactg cccagtggac actgctgttt ctgttattgc gctcgcagcc atgactctgc
      121 cccacagccc tgggagtgcc ggggagcccc aagcctccca gaccgtgcag gtccacaggc
      181 tggaacacag gcaggaggag gagcagaaag aggagcggca gcacagcctg cagatgggtt
      241 cttccgtgca gaggcggacc taccgcagca gtgaggagga acaacagttc agctctgaag
      301 actatgccct ggctgctgcc ctggccctga cagcctcctc agagttgtcc tgggaagcta
      361 agctgagacg ccagaccacc acagtggagc tggaggagcg tggacagagg cgggtaggct
      421 ttggcaatga cctggagcgg atggagctgg ccttcctacg cactcagagg ctgctgcgtc
      481 agaggcgaga ctggaaggcg ctgcggcaac ggacagagga gaaggtccga gaggccaagg
      541 aactgatcga gttgtgctct ggccgcggcc cctggttctg gatcccgctt cgatcgcatg
      601 ccgtctggga gcacaccacg gtactgctga cctgcaccgt ccagggctca cctccattcc
      661 aggtcacctg gtacaagaac gacatccgga tcgatccccg cctctttcca gccggcaagt
      721 accgtatcac caacaactac gggctgctga ccctggagat catgaggtgc acggtggagg
      781 actcggccac ctacactgtg ctggtgaaga acgcctacgg ccaggcctct tcctttgcca
      841 aagtcctcat ccgcaattac ctggggaaag atgctggctt tgactcggag atctttaaac
      901 gatctatgtt cggccccagc gcggagttta catcggtgtt gaagccaatc tttgcccaag
      961 agaaagagcc tttctccctg acctgtttgt tctcagacga tgtattagaa gctgagcaga
     1021 gaatccagtg gtacagagat ggcaggctac tgaggtcttc aacacgcagg cagatactct
     1081 acgcagaccg ccaggcctcc gtgaaggtgt cctgtgccta caaagaggac gaggggttct
     1141 acacaatccg agtctcctcg ccctttgggc cgcaggagca gagcgcctat gtctttataa
     1201 gagatgctgc agctgagaag ccaggagccc caggctcgcc actaaacgtc cggtgtctga
     1261 atgtgcatag agactgcctg accctgacct gggtcccgcc cagcgacacc cggggcagca
     1321 ccatcactgg ctattccatt gagatgtgcc agggtgattc ggaggagtgg atgccctgcc
     1381 ttaaggcccc cgggggaacc tgccggtgcc cgatccaagg cctcgttgaa ggacagagct
     1441 atcagttccg agtgcgcgcc atcagcaaag ccggcaccag tctcccttcc aaggcctcag
     1501 aagcagttgt cacgggtgac tatgatgcag tccataagag tacagagatt ccctatgacc
     1561 tgggcagcaa gatcaccatc agcaagaacg atttcgaaga tgctgtgacc attccctcag
     1621 ccccaaccaa tgtccacgcc agcgagatca gagaagccta tgcggttctg agctgggagg
     1681 agccacgccc ccggggcaga gccccgctga cttacactct ggaaaagtcc gtcatcggta
     1741 gtggaacctg ggaggccatc agcacggaaa cacccatcaa gtccccaaga ttcgccctcc
     1801 tggacttaga gaaggggaaa tcgtatgtct tcagagtgag agccttgaac cagtacggca
     1861 tgagtgatcc ctcagagccc agcgagcctg tcgccctgaa gggcaagcca gcgactctcc
     1921 ctcctccagc tcaagttcaa gctttccgaa acactcagac ctctgtctcc cttgcctggg
     1981 agcccgtgga tggtggctcg gagctcctgg gttattacat ctactcccgc gaggccggag
     2041 catcagagtg gcagactgtg aacaacaaac ccatccagga caccaagttc acagtcccag
     2101 ggctgaggac tgggaaggag tacgactttt gcatcaggtc ggtcagcgag gctggggttg
     2161 gtgagagttc agctgccaca cagccagtca gggtcaagca agcactagcc actccatcgg
     2221 ccccatatga cttcgcactc ctaaactgtg ggaagaatga aatggtcatt ggatggaaac
     2281 cccccaagcg acgcggaggc ggcaagatcc tgggctactt catggaccag catgattcag
     2341 tggagtcaga ctggcaccca gtcaaccgtc agcccatccc aagccgtgtg tgcaaggtca
     2401 ccaaccttca tgaaggccat ttctatgagt tccgagcccg ggccgtgaac tgggcaggta
     2461 ttggcgagct gtcggcaccc agcagcctgt ttgagtgcaa agagtggacg atgccggagc
     2521 caggtccccc atatgatgtg agggtgtctg aggtacaggc cacgtctgtg atgctgcagt
     2581 gggagccccc actgtatatt ggagccgggc cagtcacagg ctaccatgtc agcttccagg
     2641 agaaaggctc tgaggagtgg aagccggtca ccccagatgc cacctctgac acccacctca
     2701 gggtgtctga cttacaaccg ggaaagcaat acatgttcag ggtccaggcc atgaactcag
     2761 ctggtctggg acaaccatcg gtgcccactg accctgtgct cctggaggac aagccagacg
     2821 cccaggagat tgaagttggt gtggacgacg agggccagat ctacttggct tttgaagccc
     2881 ccgaagcccc tgacttccct gagtttcagt ggtccaagga ttaccaaggc ccaccagacc
     2941 cacagagggt ggaggtggaa gatgaaatta gcaagtccaa ggtcatcctg aaagaacctg
     3001 accttcagga cttgggcatc tactcagtgg tagtccccga tgccgacgaa gacacctctg
     3061 ctagccacac gctgacggag gaagagctga acaagctgaa gaagctgagt cacgagatca
     3121 gaaacccagt catcaagctg atctctggct ggaacgtgga aatcctcgag caaggtgagg
     3181 tgcggctgtg gctggaggtg gagaaactgt cgcccgccgc cgagctgcac ctcatcttca
     3241 acgagaagga gatcttcagc tccccgaacc gcaagatcaa ctttgaccga gagaagggct
     3301 tagtggaagt tatcatccaa caactttccg aagatgacaa ggggtcctac accgcccagc
     3361 tccaagatgg aaaagccaag aaccagatca ctctcgccct ggtggatgac gaatttgaca
     3421 agctcctgag aaaggcagac gcaaagagaa gagactggaa gagaaaacag ggtccctatt
     3481 tccaggagcc tttgacctgg aaggtcacag atgactgcca agtgcttctg tcgtgcaagg
     3541 taacaaacac gaagaaggag agtcgctttc agtggttctt ccagaagaaa gaggcgccac
     3601 atgggcagta caacccgccg accggagatg ggagtctctc cattgagggg ttttccaaag
     3661 aaaaccaggg agtctacaga gccgtggttt ctgacgagag aggggaagat gacactgtgc
     3721 tggacctcac aggtgaagcc ctagatgccg tcctcactga gctgggcagg attggtgctc
     3781 tctctgcaac cccactgaaa atccagggga ctgaagaggg catccggctc ttcagcaagg
     3841 tcaaatacta caacgtggac tacatgaaga cggcgtggtt ccacaaagat aagcggctgg
     3901 agagtggcga tcgggtacgg gcaggcacca ccctggatga gatttggctc cacatcctgg
     3961 accctaagga ctcagataaa ggcaaataca ccctggagat cactgctggg aaggaagtcc
     4021 ggcagctctc agcagacctg tctggacaag cttttgatga cgccctggca gagcaccaga
     4081 gactgaaggc cttggctgtc attgagaaga atcgggctaa agtggtaagg ggcctgccag
     4141 acgtggccac catcatggaa gataagaccc tgtgcctgac ctgtgtcatc tcgggagacc
     4201 cgtcccctga aatctcttgg ctaaagaacg accagcctat ctccttcttt gaccgatacc
     4261 acatggaggt gaagggtacg gaggtcaccg tcaccattga caaggtcacc agcgaagata
     4321 gcgggcgcta tggaatcttc gtcaagaaca agtatggttc ggagacaggc caggtcacca
     4381 tcagcgtgtt caaacatggg gaggagccca aggagctgaa gaagaagtaa tgggagcatt
     4441 ggggggcagc ctgagatcca ccctacaacg accagcaggc cagcccatgg gtcataacct
     4501 agcacaggct atggggatag gacaggggaa gggaagggac agggacatga cagacctgga
     4561 tctaacacac aaaagaggag aagcaaagat tttgctgggg ttctcagagg actccagaat
     4621 gtggggtgca ccctggcctt agaagtcaga agctggagtg taaaactttg tttccacaaa
     4681 agctcttcac aagcctcgcc ttttcacatc catcagatgg gcattcctat atattccttg
     4741 gggatttata aaaatccctt atcaatctct gtcagtgggc cacagaagga ggcacctttg
     4801 ctctgcaggg gacaactggc aaagctaaga gtttggttgt gacaaccgga agtatttact
     4861 ggcattgagt gggttaatac cacagatgct ggtgaacacc gtaaggctcc tcccacggca
     4921 cagaatatat tctcttttaa aataggactg tcacctttct acgtgtccgt cactctttgg
     4981 acatatagca tacacaaggc tgaggatggc cccaaagcta agaagataaa cattacacag
     5041 gccccactca gaaagggact ggggtgcagg ggtcgccagg gcaagacagg agatactaaa
     5101 gttcactaaa tgagtaaaag gaaagtacct tcaatgatca gaggaagcgg gcaatgattg
     5161 agagatgcag agcttggcaa cacccttcca cattgcgtgg gacagtgtcg ggccctgaaa
     5221 gctgaatcca gtttggctgt ggagatgaga ggacacctca aggagcagac atggtgaggg
     5281 gtgaggaaga aaggagtctc cctaggcgac ctgggaagcc aggcagtgca ggtgatgacc
     5341 ttcggggctt cttccaacat ggagcctata tggcccatgg cagacacttt ggctggcctt
     5401 actcagtgga tctcggtaca caactggaca tttctctgcc ttccgacttc ctccaacaag
     5461 atgtgggagg gagggaggag ttatcaaatt ctagctgttt gctgccaaat cttagatgat
     5521 tttggaaatt ataaaggagg aaataaaaaa aagacaatct gtattttcat caagaggc
//
