LOCUS       NM_001414184            5449 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus myomesin 2 (Myom2), transcript variant 4, mRNA.
ACCESSION   NM_001414184
VERSION     NM_001414184.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5449)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5449)
  AUTHORS   Hayashi,S., Manabe,I., Suzuki,Y., Relaix,F. and Oishi,Y.
  TITLE     Klf5 regulates muscle differentiation by directly targeting
            muscle-specific genes in cooperation with MyoD in mice
  JOURNAL   Elife 5, e17462 (2016)
   PUBMED   27743478
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5449)
  AUTHORS   Harms,M.J., Ishibashi,J., Wang,W., Lim,H.W., Goyama,S., Sato,T.,
            Kurokawa,M., Won,K.J. and Seale,P.
  TITLE     Prdm16 is required for the maintenance of brown adipocyte identity
            and function in adult mice
  JOURNAL   Cell Metab 19 (4), 593-604 (2014)
   PUBMED   24703692
REFERENCE   4  (bases 1 to 5449)
  AUTHORS   Tripathi,P., Wang,Y., Casey,A.M. and Chen,F.
  TITLE     Absence of canonical Smad signaling in ureteral and bladder
            mesenchyme causes ureteropelvic junction obstruction
  JOURNAL   J Am Soc Nephrol 23 (4), 618-628 (2012)
   PUBMED   22282597
REFERENCE   5  (bases 1 to 5449)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   6  (bases 1 to 5449)
  AUTHORS   Yang,X.Y., Yang,T.T., Schubert,W., Factor,S.M. and Chow,C.W.
  TITLE     Dosage-dependent transcriptional regulation by the calcineurin/NFAT
            signaling in developing myocardium transition
  JOURNAL   Dev Biol 303 (2), 825-837 (2007)
   PUBMED   17198697
REFERENCE   7  (bases 1 to 5449)
  AUTHORS   Hirschy,A., Schatzmann,F., Ehler,E. and Perriard,J.C.
  TITLE     Establishment of cardiac cytoarchitecture in the developing mouse
            heart
  JOURNAL   Dev Biol 289 (2), 430-441 (2006)
   PUBMED   16337936
REFERENCE   8  (bases 1 to 5449)
  AUTHORS   Carlsson,L., Li,Z., Paulin,D. and Thornell,L.E.
  TITLE     Nestin is expressed during development and in myotendinous and
            neuromuscular junctions in wild type and desmin knock-out mice
  JOURNAL   Exp Cell Res 251 (1), 213-223 (1999)
   PUBMED   10438587
REFERENCE   9  (bases 1 to 5449)
  AUTHORS   Steiner,F., Weber,K. and Furst,D.O.
  TITLE     Structure and expression of the gene encoding murine M-protein, a
            sarcomere-specific member of the immunoglobulin superfamily
  JOURNAL   Genomics 49 (1), 83-95 (1998)
   PUBMED   9570952
REFERENCE   10 (bases 1 to 5449)
  AUTHORS   Schiaffino,S. and Reggiani,C.
  TITLE     Molecular diversity of myofibrillar proteins: gene regulation and
            functional significance
  JOURNAL   Physiol Rev 76 (2), 371-423 (1996)
   PUBMED   8618961
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124604.4 and AC125235.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.10435.1,
                                           SRR10223971.8430.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01766820, SAMN01766828
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                AC124604.4         164954-165040
            88-416              AC124604.4         166086-166414
            417-466             AC124604.4         167674-167723
            467-592             AC124604.4         168100-168225
            593-710             AC124604.4         171144-171261
            711-866             AC124604.4         172995-173150
            867-1005            AC124604.4         176675-176813
            1006-1163           AC124604.4         176949-177106
            1164-1256           AC124604.4         177973-178065
            1257-1345           AC124604.4         185120-185208
            1346-1396           AC124604.4         185298-185348
            1397-1561           AC124604.4         188160-188324
            1562-1723           AC124604.4         188563-188724
            1724-1865           AC124604.4         190531-190672
            1866-2065           AC124604.4         191762-191961
            2066-2119           AC124604.4         192562-192615
            2120-2247           AC124604.4         205643-205770
            2248-2431           AC124604.4         206476-206659
            2432-2606           AC124604.4         209784-209958
            2607-2728           AC124604.4         211368-211489
            2729-2916           AC124604.4         213581-213768
            2917-3043           AC124604.4         215664-215790
            3044-3222           AC124604.4         216067-216245
            3223-3337           AC124604.4         218049-218163
            3338-3494           AC124604.4         219020-219176
            3495-3601           AC124604.4         219261-219367
            3602-3646           AC125235.3         181856-181900       c
            3647-3783           AC125235.3         181360-181496       c
            3784-3928           AC125235.3         177905-178049       c
            3929-3988           AC125235.3         177714-177773       c
            3989-4056           AC125235.3         176358-176425       c
            4057-4170           AC125235.3         173177-173290       c
            4171-4258           AC125235.3         172917-173004       c
            4259-4297           AC125235.3         172210-172248       c
            4298-4403           AC125235.3         170424-170529       c
            4404-4567           AC125235.3         166713-166876       c
            4568-4604           AC125235.3         166476-166512       c
            4605-4627           AC125235.3         164989-165011       c
            4628-4683           AC125235.3         164465-164520       c
            4684-5449           AC125235.3         162236-163001       c
FEATURES             Location/Qualifiers
     source          1..5449
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 7.63 cM"
     gene            1..5449
                     /gene="Myom2"
                     /note="myomesin 2"
                     /db_xref="GeneID:17930"
                     /db_xref="MGI:MGI:1328358"
     exon            1..87
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            88..416
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            417..466
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            467..592
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            593..710
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     CDS             604..4995
                     /gene="Myom2"
                     /note="isoform 1 is encoded by transcript variant 4;
                     skeletal muscle 165kDa protein; skeletal muscle 165kD
                     protein"
                     /codon_start=1
                     /product="myomesin-2 isoform 1"
                     /protein_id="NP_001401113.1"
                     /db_xref="GeneID:17930"
                     /db_xref="MGI:MGI:1328358"
                     /translation="MSLVAVPFYQKRHKHFDQSYRNIQTRYLLDQYALKKQATTQSSS
                     QRSLTERSSSKRASSQSSAGAMTCRLCAKRVSASEEEEVENENRYRSQAASYGEAKRQ
                     RFLSELAQLEENVHLARSQARDKLDKYFMEQTVEDNLAWERHSFEDRMSRAPEILVRL
                     RSHTIWERMSVRLCFTVQGFPTPVVQWYKDGSLICQAGEPGKYRIESRYGVHTLEINR
                     ANFEDTATYSAVATNSHGQVSTNAAVVVRRYRGEEEPFHSVGLPIGLPLSSVIPYTHF
                     DVQFLEKFGVTFRREGETVTLKCTLLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFG
                     EGQASLSFSHLNKDDEGLYTLRIVSRGGVSDHSAFMFVRDADPLVTGAPGAPMDLQCH
                     DANRDYVIVTWKPPNTTTESPVIGYFIDKCEVGTNNWVQCNDAPVKICKYPVTGLFEG
                     RSYVFRVRAVNNAGISRPSRISDAVAALDPVDLRRLQAIHLEGEKEIVIYQDDLEGDV
                     QIPGPPTNVQASEVSRNYVVLSWDPPSPRGKDPLMYFIEKSAVGSGSWQRVNAQTAVR
                     SPRYAVFDLAEGKSYVFRVLSANKHGLSDPSEITPPIQAQDMIVVPSAPGRVLASRNT
                     KTSVVVQWDRPKHEEDLLGYYVDCCVAGTNMWEPCNHKPIGYNRFVVHGLTTGEQYIF
                     RVKAVNAVGTSENSQESEVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS
                     AIIGYYLDKREVHHKNWHEVNSSPVKERILTVEGLTEGSLYEFKIAATNLAGIGQPSD
                     PSEHFKCEAWTDPEPGPAYDLTFCEVRDTSLVILWKAPVYSGSSPVSGYFVDFKEEDS
                     GEWKTTSEAATPNRYLKVCDLQQGKTYVFRIRAVNASGPGKPSDTSEPVLVEARPGTK
                     EISAGVDEEGNIYLGFDCQEMTDASQFTWCKAYEEIADEERFEVHTEGDHSKLYFKNP
                     DKEDLGTYSVSVSDTDGVSSSFVLDEEELERLMALSNEIKNPTIPLKSELAYEIFDKG
                     QVRFWLQAEHLSPDASFRFIINDREVSDSDTHRIKCDRSTGMIEMVMDRFTIENEGTY
                     TVQIQDGKAKNQSSLVLIGDAFKAVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEV
                     RLVCKVANTKRETVFKWLKDDVLYETETPPDLEKGVCELLIPKLSKKDHGEYKATLKD
                     DRGQDVSVLEVGGKVYEDMILAMSRVCGASASPLKVLCTPEGIRLQCFMKYFTEEMKV
                     SWYHKEAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDSHQRSLDLSG
                     QAFDEAYAEFQQLKAAAFAEKNRGKVIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVVW
                     FKNDKDIELSEHFLVKMEQSKYVSLTIQGVTAEDSGKYSINVKNKYGGEKIDVTVSVY
                     KHGEKIPDISPPQQAKPKLIPASTSSD"
     exon            711..866
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1005
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1163
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1256
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..1345
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1396
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1561
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..1723
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1865
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..2065
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2119
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2120..2247
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2248..2431
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2432..2606
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2728
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2729..2916
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2917..3043
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3044..3222
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3223..3337
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3338..3494
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3495..3601
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3602..3646
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3647..3783
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3784..3928
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3929..3988
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3989..4056
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4057..4170
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4171..4258
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4259..4297
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4298..4403
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4404..4567
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4568..4604
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4605..4627
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4628..4683
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4684..5449
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5432..5437
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myom2"
                     /note="hexamer: AATAAT"
     polyA_site      5449
                     /gene="Myom2"
                     /note="major polyA site"
ORIGIN      
        1 agggagaaat tagctctgct gtcttgggcc agtgtctggg aaactcttcc acagtagttt
       61 tctcctctgc tggctcttct cctttggggc tatcaacagt gatctgcctg ccaggaggga
      121 aaggctcctg ctgcatttga gggccaggct ggaaataccc agctttctct gtcacctgcc
      181 caacattcct tctttcccga gtgcaacaaa aacaggaagc aaagagcacg tggaatgaag
      241 acacttaaaa gtgatactga ataatcggag gccccagata aaaagctatc ctaggagcca
      301 aagacttagt ctctggggct cacgccaact ccatgtgtcc tctggagatg ctgtgcccat
      361 gagttcacca aatgacacct ctggctctgc aaagacagag tggagcaaaa gcgtggggat
      421 catcagaacc tgatctttga agaggaggca cgcctcatct ttttggtctt ggagcaacac
      481 acgtcagttg ctcaaaaggc tgtggtttgg aagatgggtg gagtaaagag tacctgcact
      541 tgaagagcgc tcggcaatcc tgactttgat ataagaggac aaaacactcc aagaacactc
      601 aagatgtccc tggtcgcagt gcctttctac cagaaaagac acaagcactt tgaccagtca
      661 tatcgaaaca tccaaaccag gtacctcctg gaccaatatg cattgaaaaa gcaagcaacc
      721 acccagtcat cctcccagag gtctcttaca gagaggtcct cttcgaagag agcttccagt
      781 cagagctctg ctggggcgat gacctgcagg ctctgtgcaa agcgggtgag cgcatcagaa
      841 gaggaggaag ttgaaaatga aaacaggtac cggtctcaag cggcttctta cggagaagct
      901 aagaggcagc gtttcctcag tgagctggcc cagctggagg agaatgtcca cctggcccgg
      961 tcacaggctc gggacaagct agacaagtac ttcatggagc agacggtgga agacaatctg
     1021 gcgtgggaga gacactcatt tgaagaccga atgagcaggg cccctgagat cctggtgagg
     1081 ttaaggtccc acaccatctg ggagcggatg tctgtgaggc tctgtttcac tgtgcaagga
     1141 ttccccacgc ctgtggtgca atggtacaaa gacggcagtc tgatctgcca ggcaggggag
     1201 ccaggcaagt accggattga gagcaggtac ggagtgcaca ctctggagat caacagggcc
     1261 aactttgagg acaccgccac ctattcagca gtagcaacta attcccatgg acaagtgtct
     1321 accaatgctg cggtggtggt gagaaggtac cgaggagaag aggaaccttt ccactcagta
     1381 ggactcccaa ttggattgcc cctttcatct gtgatcccgt acacacattt tgatgtccag
     1441 tttttggaga aattcggggt caccttcaga agagagggcg agacagtcac actcaagtgc
     1501 acgctattgg tgacgccaga tctgaagaga gtacagccac gagctgagtg gtaccgggat
     1561 gatgtgctgc tgaaagagtc caagtggacc aagatgttct ttggagaagg ccaggcctcc
     1621 ctgtccttca gccacctgaa caaggatgac gaggggctgt acactttgag gattgtgtcc
     1681 cggggtggag tcagcgacca cagcgctttc atgtttgtca gagatgctga cccactggtc
     1741 acaggggctc ctggggcacc catggacctg cagtgccatg atgccaaccg agactatgtc
     1801 atcgtgactt ggaaaccacc caacaccact actgagagcc ctgtcattgg ctacttcatt
     1861 gacaaatgtg aggtgggaac taacaactgg gtccagtgta acgatgcacc agtaaagatc
     1921 tgcaagtacc ccgtcaccgg acttttcgaa ggaagatcgt atgtgttccg cgtgagggct
     1981 gtcaataatg ccggcattag caggccttcc aggatctccg atgctgtggc cgcccttgac
     2041 cctgttgacc tcagaagatt gcaagcgatt catttggaag gagagaaaga aatcgtcatc
     2101 taccaggatg atcttgaagg tgatgttcag attccagggc ctcccactaa tgtccaggcc
     2161 tcagaggtca gcaggaacta cgttgtcctc agctgggatc ctccatctcc ccgcggcaag
     2221 gatcccttaa tgtacttcat cgagaagtct gcagttggga gtggcagctg gcagagggtc
     2281 aatgctcaaa cggcggtgag atctcctcgg tatgctgtct ttgacttggc tgaagggaag
     2341 tcctacgtgt tccgggtttt gtcagccaat aaacatggcc tgagtgaccc atcagagata
     2401 acaccaccta ttcaggcaca ggacatgatt gtggtcccct ctgctcctgg ccgggtgctt
     2461 gcctccagga atacaaagac atccgtcgta gtccagtggg acagaccaaa gcatgaagag
     2521 gacctgctgg gctactatgt ggactgctgt gtggcgggaa caaacatgtg ggaaccatgc
     2581 aaccacaaac ccattggata taacaggttt gtggtacacg gcttaaccac cggtgagcag
     2641 tacatcttcc gggtcaaggc tgtcaatgcc gtggggacca gcgagaactc tcaggagtca
     2701 gaggtcatca aggtccaggc ggccctcact gtcccctctc atccctatgg gattaccctt
     2761 ctcaactgtg atggccactc catgaccctg ggctggaaag tgcctaagtt cagcggcggc
     2821 tcggccatca taggttacta tctggacaag cgagaagtgc atcacaagaa ctggcacgag
     2881 gtcaactctt cacctgtcaa agagaggatc ttaacggtgg aaggtttgac tgaaggctcc
     2941 ttgtatgagt tcaaaattgc tgctaccaac ctggctggga tcgggcagcc atcggatccc
     3001 agtgagcatt tcaagtgtga ggcctggaca gatccagaac ctggtcctgc ctatgacctg
     3061 acgttctgtg aggtccgaga cacttctctg gtcattctgt ggaaagctcc cgtttactcg
     3121 ggcagcagtc ctgtttctgg atattttgtg gattttaagg aagaggattc tggggagtgg
     3181 aagaccacca gcgaggcagc aactccaaat cgctacttaa aggtctgtga cctgcagcag
     3241 ggtaagacct atgtattcag aattcgagca gtgaatgcca gtggaccagg aaagccgtca
     3301 gacacgtctg agcctgtgtt ggtggaggcc cggccaggca caaaggagat cagcgctggt
     3361 gtggatgagg agggcaacat ctaccttggg tttgactgcc aggaaatgac agatgcctcg
     3421 cagttcacct ggtgtaaggc ctacgaggag atcgctgatg aggagcgatt tgaggttcac
     3481 acggagggtg accactcaaa gctgtacttt aagaatccag ataaagaaga cctagggaca
     3541 tattctgtat ctgtaagtga cacggatggt gtgtcctcca gctttgttct ggacgaggaa
     3601 gaacttgagc gtttgatggc actgagcaat gagataaaga accccacaat tccactgaag
     3661 tcagaattag cttatgagat tttcgataag ggccaggtcc gattctggct gcaggcagag
     3721 cacctttccc ctgatgccag cttccggttc atcattaatg acagagaggt ttctgacagt
     3781 gacacgcaca gaattaaatg tgacagatcg acaggcatga ttgagatggt catggatcgg
     3841 ttcactattg aaaatgaagg gacctacact gtgcagattc aagatggaaa agccaagaat
     3901 cagtcatcac tggtgctcat tggagatgca ttcaaggctg tcctagaaga ggctgaattt
     3961 caaaggaagg aatttctacg gaaacaaggc cctcattttg ctgaatattt gcactgggat
     4021 gtcactgaag agtgtgaagt tcggcttgtc tgtaaggttg caaacaccaa gagggaaact
     4081 gttttcaaat ggctcaagga cgatgttctt tacgaaacgg agacaccgcc agacctggag
     4141 aagggggtct gtgagctgct tatacccaag ttgtctaaga aggaccatgg tgaatacaaa
     4201 gcaaccttga aagatgacag aggtcaggat gtatctgtcc tggaagtagg tggcaaagtg
     4261 tacgaggaca tgatcttagc catgagtcgt gtgtgtggag cctctgcctc acccctgaag
     4321 gttctctgca ctccagaggg catccggctt cagtgcttca tgaagtactt cacagaggaa
     4381 atgaaggtca gctggtatca caaagaggcc aagatctcct ccagtgagca catgcggatc
     4441 ggagggagcg aggagatggc atggctgcag atctgtgagc ccacagagaa ggacaagggg
     4501 aaatacacgt ttgagatttt cgatggcaaa gacagccacc aacgctcgct ggacctctct
     4561 ggacaagctt ttgacgaagc ctacgctgag ttccagcagc tcaaggctgc tgcttttgca
     4621 gagaagaatc gcggcaaggt gattggcggc ttaccagacg tggtgaccat aatggaaggc
     4681 aagaccttga acctcacctg cactgtgttt ggaaaccccg accctgaggt ggtctggttt
     4741 aagaacgaca aggacattga gctcagcgag cacttcttgg tgaagatgga gcagtccaag
     4801 tatgtcagcc tgaccatcca gggggtgacg gccgaggact cgggcaagta cagcatcaac
     4861 gtgaagaata aatacggagg agagaagatc gatgtcactg tcagtgtgta caaacacggg
     4921 gagaagatcc cagacatctc acctccccag caggccaaac ccaagctcat cccagcttcc
     4981 acctcatctg attaagggaa tcccgtctgc cctggggctg gagagatggg agggaggtct
     5041 taggatgttg tatgctgtgc tgagtgggtg ccagtttggc gtgatgtcac gtgtggccag
     5101 actggcgacc gtacactagg tttttgatct tgcactttgc gatgcaaatt atctgtgtgg
     5161 aggggaagcg aatgtttctg aacataaggc tctaagactc gtgtgaggct gagagtgaat
     5221 ggcagtggag agtgggctga gagagggcag ctggcacatc cagggtcatg ggcatgtgga
     5281 ctgaggctca gatggtccta gcatgtggta gtctggatag ttattaccat cctgagggga
     5341 gtgggggggg ggctgcaggg cacatttctg gaaacccttt gtggagcctt tgagcatggt
     5401 acgtgcttac ctttttgtct tgctttaggc taataataat aataaaaaa
//
