LOCUS       NM_001370611            5351 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus myosin IC (Myo1c), transcript variant 4, mRNA.
ACCESSION   NM_001370611 XM_006532429
VERSION     NM_001370611.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5351)
  AUTHORS   Aslund,A., Bokhari,M.H., Wetterdal,E., Martin,R., Knolker,H.J. and
            Bengtsson,T.
  TITLE     Myosin 1c: A novel regulator of glucose uptake in brown adipocytes
  JOURNAL   Mol Metab 53, 101247 (2021)
   PUBMED   33965643
  REMARK    GeneRIF: Myosin 1c: A novel regulator of glucose uptake in brown
            adipocytes.
REFERENCE   2  (bases 1 to 5351)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5351)
  AUTHORS   Li,K., Zhang,K., Wang,H., Wu,Y., Chen,N., Chen,J., Qiu,C., Cai,P.,
            Li,M., Liang,X. and Su,D.
  TITLE     Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice
  JOURNAL   Metabolism 114, 154349 (2021)
   PUBMED   32888949
REFERENCE   4  (bases 1 to 5351)
  AUTHORS   Ji,H.H. and Ostap,E.M.
  TITLE     The regulatory protein 14-3-3beta binds to the IQ motifs of
            myosin-IC independent of phosphorylation
  JOURNAL   J Biol Chem 295 (12), 3749-3756 (2020)
   PUBMED   31811090
  REMARK    GeneRIF: The regulatory protein 14-3-3beta binds to the IQ motifs
            of myosin-IC independent of phosphorylation.
REFERENCE   5  (bases 1 to 5351)
  AUTHORS   Arif,E., Solanki,A.K., Srivastava,P., Rahman,B., Tash,B.R.,
            Holzman,L.B., Janech,M.G., Martin,R., Knolker,H.J.,
            Fitzgibbon,W.R., Deng,P., Budisavljevic,M.N., Syn,W.K., Wang,C.,
            Lipschutz,J.H., Kwon,S.H. and Nihalani,D.
  TITLE     The motor protein Myo1c regulates transforming growth
            factor-beta-signaling and fibrosis in podocytes
  JOURNAL   Kidney Int 96 (1), 139-158 (2019)
   PUBMED   31097328
  REMARK    GeneRIF: The motor protein Myo1c regulates transforming growth
            factor-beta-signaling and fibrosis in podocytes.
REFERENCE   6  (bases 1 to 5351)
  AUTHORS   Hamilton,B.A., Smith,D.J., Mueller,K.L., Kerrebrock,A.W.,
            Bronson,R.T., van Berkel,V., Daly,M.J., Kruglyak,L., Reeve,M.P.,
            Nemhauser,J.L., Hawkins,T.L., Rubin,E.M. and Lander,E.S.
  TITLE     The vibrator mutation causes neurodegeneration via reduced
            expression of PITP alpha: positional complementation cloning and
            extragenic suppression
  JOURNAL   Neuron 18 (5), 711-722 (1997)
   PUBMED   9182797
REFERENCE   7  (bases 1 to 5351)
  AUTHORS   Crozet,F., el Amraoui,A., Blanchard,S., Lenoir,M., Ripoll,C.,
            Vago,P., Hamel,C., Fizames,C., Levi-Acobas,F., Depetris,D.,
            Mattei,M.G., Weil,D., Pujol,R. and Petit,C.
  TITLE     Cloning of the genes encoding two murine and human cochlear
            unconventional type I myosins
  JOURNAL   Genomics 40 (2), 332-341 (1997)
   PUBMED   9119401
REFERENCE   8  (bases 1 to 5351)
  AUTHORS   Whitmer,J.D., Koslovsky,J.S., Bahler,M. and Mercer,J.A.
  TITLE     Chromosomal location of three unconventional myosin heavy chain
            genes in the mouse
  JOURNAL   Genomics 38 (2), 235-237 (1996)
   PUBMED   8954808
REFERENCE   9  (bases 1 to 5351)
  AUTHORS   Hasson,T., Skowron,J.F., Gilbert,D.J., Avraham,K.B., Perry,W.L.,
            Bement,W.M., Anderson,B.L., Sherr,E.H., Chen,Z.Y., Greene,L.A.,
            Ward,D.C., Corey,D.P., Mooseker,M.S., Copeland,N.G. and
            Jenkins,N.A.
  TITLE     Mapping of unconventional myosins in mouse and human
  JOURNAL   Genomics 36 (3), 431-439 (1996)
   PUBMED   8884266
REFERENCE   10 (bases 1 to 5351)
  AUTHORS   Sherr,E.H., Joyce,M.P. and Greene,L.A.
  TITLE     Mammalian myosin I alpha, I beta, and I gamma: new widely expressed
            genes of the myosin I family
  JOURNAL   J Cell Biol 120 (6), 1405-1416 (1993)
   PUBMED   8449986
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591440.7.
            
            On Nov 15, 2022 this sequence version replaced NM_001370611.1.
            
            Summary: This gene encodes a member of the unconventional myosin
            protein family, which are actin-based molecular motors. The protein
            is found in the cytoplasm, and one isoform with a unique N-terminus
            is also found in the nucleus. The protein functions in
            intracellular vesicle transport to the plasma membrane. The nuclear
            isoform associates with RNA polymerase I and II and functions in
            transcription initiation. Multiple transcript variants encoding
            different isoforms have been found for this gene. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.11740.1,
                                           SRR10223970.14167.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-246               AL591440.7         65334-65579         c
            247-402             AL591440.7         58451-58606         c
            403-518             AL591440.7         58230-58345         c
            519-717             AL591440.7         57548-57746         c
            718-798             AL591440.7         57379-57459         c
            799-978             AL591440.7         55748-55927         c
            979-1077            AL591440.7         55567-55665         c
            1078-1191           AL591440.7         55086-55199         c
            1192-1263           AL591440.7         54930-55001         c
            1264-1383           AL591440.7         54484-54603         c
            1384-1466           AL591440.7         54282-54364         c
            1467-1572           AL591440.7         53971-54076         c
            1573-1653           AL591440.7         53783-53863         c
            1654-1745           AL591440.7         53435-53526         c
            1746-1840           AL591440.7         50486-50580         c
            1841-1887           AL591440.7         50359-50405         c
            1888-1968           AL591440.7         50181-50261         c
            1969-2074           AL591440.7         47812-47917         c
            2075-2192           AL591440.7         47571-47688         c
            2193-2306           AL591440.7         46977-47090         c
            2307-2383           AL591440.7         46824-46900         c
            2384-2452           AL591440.7         46249-46317         c
            2453-2537           AL591440.7         46067-46151         c
            2538-2697           AL591440.7         45808-45967         c
            2698-2781           AL591440.7         45472-45555         c
            2782-2875           AL591440.7         44812-44905         c
            2876-2931           AL591440.7         44663-44718         c
            2932-3067           AL591440.7         44376-44511         c
            3068-3138           AL591440.7         44223-44293         c
            3139-3236           AL591440.7         44043-44140         c
            3237-3336           AL591440.7         43847-43946         c
            3337-5351           AL591440.7         41474-43488         c
FEATURES             Location/Qualifiers
     source          1..5351
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.92 cM"
     gene            1..5351
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /note="myosin IC"
                     /db_xref="GeneID:17913"
                     /db_xref="MGI:MGI:106612"
     exon            1..246
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..3363
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /note="isoform c is encoded by transcript variant 4;
                     myosin-Ic; unconventional myosin-Ic; myosin I beta;
                     nuclear myosin I beta; MMI-beta; myosin-Ibeta"
                     /codon_start=1
                     /product="unconventional myosin-Ic isoform c"
                     /protein_id="NP_001357540.1"
                     /db_xref="CCDS:CCDS88191.1"
                     /db_xref="GeneID:17913"
                     /db_xref="MGI:MGI:106612"
                     /translation="MALQVELIPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARD
                     RVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHME
                     RYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAET
                     CPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHIL
                     SYLLEKSRVVHQNHGERNFHVFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVS
                     SINDKSDWKVMRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQ
                     LKYLTRLLGVEGTTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTW
                     LVRKINRSLASKDAESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFI
                     ELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLT
                     FLEKLEDTVKPHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLL
                     FRNLKETMCSSMNPIMAQCFDKSELSDKKRPETVATQFKMSLLQLVEILRSKEPAYIR
                     CIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPET
                     WPMWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATK
                     IQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFILRH
                     SPRCPENAFFLDHVRASFLLNLRRQLPRNVLDTSWPTPPPALREASELLRELCMKNMV
                     WKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPRVLQSL
                     GSEPIQYAVPVVKYDRKGYKPRPRQLLLTPSAVVIVEDAKVKQRIDYANLTGISVSSL
                     SDSLFVLHVQREDNKQKGDVVLQSDHVIETLTKTALSADRVNNININQGSITFAGGPG
                     RDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR"
     exon            247..402
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            403..518
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            519..717
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            718..798
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            799..978
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1077
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1191
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1263
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1383
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1466
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1572
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1653
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1654..1745
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1840
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1841..1887
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..1968
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2074
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2192
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2193..2306
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2383
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2384..2452
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2537
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2697
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2781
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2782..2875
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..2931
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3067
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            3068..3138
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            3139..3236
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            3237..3336
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     exon            3337..5351
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4614..4619
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /note="hexamer: AATAAA"
     polyA_site      4637
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /note="major polyA site"
     regulatory      5329..5334
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /note="hexamer: CATAAA"
     regulatory      5334..5339
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
                     /note="hexamer: AATAAA"
     polyA_site      5347
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
     polyA_site      5351
                     /gene="Myo1c"
                     /gene_synonym="mm1beta; MMIb; MYO1E; myr2; NMI"
ORIGIN      
        1 agacctggac tgctccagct gtgtcctgag aagctggacc agccacatcc ccaggggctg
       61 gagttgaagc aggaccaact ggccttccca gcgtgagcca gtggagccgc tggagccagt
      121 gggccaccgg acagtgtttg cgttctgcag gctggccctc cacacagcgg aatggcactc
      181 caagtagaac tgataccaac gggagagatc atccgtgtgg tccatcccca caggccatgc
      241 aaactcgccc tgggcagtga cggggttcga gtgaccatgg agagcgcctt gactgcccga
      301 gaccgggtag gggtgcagga ctttgtcctg ctggagaatt tcaccagtga ggctgccttc
      361 attgagaacc tccggcggcg gttccgggag aacctcattt atacctacat cggtcctgtc
      421 ctagtctctg tcaatcccta ccgagaccta cagatctaca gccggcagca tatggaacgc
      481 taccgtggtg tcagtttcta tgaagtacca cctcatttgt ttgcagtggc tgacactgta
      541 taccgggcac ttcgtactga gcgtcgggac caggcagtga tgatttctgg agagagtggg
      601 gcaggcaaga cagaggccac caagagactg ctccagttct atgcagagac ctgcccagcc
      661 cctgaacggg gtggcgcagt gcgagaccgc ctgttgcaga gcaaccccgt gttagaggcc
      721 tttgggaatg ccaagactct ccgcaacgat aactccagcc ggtttggaaa gtacatggat
      781 gtgcagtttg acttcaaggg tgcccccgtg ggaggccaca ttctcagtta cctcctggaa
      841 aagtcccggg tggtgcacca aaatcacgga gagcggaact tccacgtctt ttaccagcta
      901 ctggaggggg gcgaggagga gactctccgt cggctgggct tggaacggaa cccccagagc
      961 tacttgtacc tggtgaaggg ccagtgtgcc aaggtctcct ccatcaacga caagagtgac
     1021 tggaaggtta tgaggaaggc gctgtccgtc attgacttca ctgaggatga agtggaggac
     1081 ttgctcagca tcgtggccag cgtcctacat ctgggcaaca tccactttgc tgctgacgag
     1141 gacagcaatg cccaggttac tactgagaac cagctcaaat atctgaccag gctccttggt
     1201 gtggaaggta caacacttag ggaagccctg acccacagga agatcatcgc caagggggaa
     1261 gagctcctga gcccactgaa ccttgaacag gcggcatatg caagggatgc gcttgccaag
     1321 gctgtgtaca gccggacatt cacctggctg gtcagaaaga tcaataggtc actggcctct
     1381 aaggacgctg agagccccag ctggcgaagc accacggttc ttgggctcct ggacatttac
     1441 ggctttgaag tgtttcagca taacagcttc gagcagttct gcatcaacta ctgcaatgag
     1501 aagctgcagc agctcttcat cgagctgact ctcaagtcgg agcaggagga atacgaggct
     1561 gagggcatcg cgtgggaacc tgtccagtac ttcaacaaca agatcatctg tgacctggta
     1621 gaggagaagt tcaagggcat catctccatc ttggatgaag agtgcctgcg tcctggggag
     1681 gccacggacc tgacctttct ggagaagttg gaggacactg tcaagcccca ccctcacttc
     1741 ctgacgcaca agctcgctga ccagaagacc aggaaatctc tagaccgagg ggagttccgc
     1801 cttctgcatt atgctggaga ggtgacctac agtgtgactg ggtttctgga taaaaacaat
     1861 gacctcctct tccggaacct gaaggagacc atgtgcagct caatgaaccc catcatggcc
     1921 cagtgctttg acaagagtga gctcagtgac aagaagcggc cagagacggt ggccacccag
     1981 ttcaagatga gcctcctgca gctcgtggag atcctgaggt ctaaggagcc tgcctatatc
     2041 cggtgcatca agccaaacga cgccaagcag ccgggtcgct ttgatgaggt gctcatccga
     2101 catcaggtga agtacctggg actgatggag aatctgcgcg tgcgcagagc tggctttgcc
     2161 tatcgtcgca aatatgaggc tttcctgcag aggtacaagt cactgtgccc agagacatgg
     2221 cccatgtggg caggacggcc ccaggatggt gtggccgtgt tggtcagaca cctcggctac
     2281 aagccagaag agtacaaaat gggcaggact aagatcttca tccgatttcc caagaccttg
     2341 tttgccacag aggactccct ggaagtccgg cggcagagtc tagccaccaa gatccaggcg
     2401 gcctggaggg gctttcattg gcgacagaaa tttctccggg tgaagcgatc agccatctgt
     2461 atccagtcat ggtggcgtgg cacactgggc cggaggaagg cagccaagag gaagtgggca
     2521 gcccagacca tccgtcgact catccgtggc ttcattttgc gccattcacc ccggtgccct
     2581 gagaatgcct tcttcttgga ccacgtgcgc gcctcatttt tgcttaacct gaggcggcaa
     2641 ctgccccgga atgttctgga cacctcctgg cccacacccc cacctgccct gagagaggcc
     2701 tcagaactgc tacgggaact gtgcatgaag aacatggtgt ggaagtactg ccggagcatc
     2761 agccctgagt ggaagcagca gctgcagcaa aaggcggtgg ctagtgaaat tttcaagggc
     2821 aagaaggaca actaccccca gagtgtcccc agactcttca ttagcacacg gcttggcaca
     2881 gaggagatca gccccagagt gcttcaatcc ttgggctctg aacccatcca gtatgccgtg
     2941 cccgtggtaa aatacgaccg taagggttac aagcctcgcc cccggcagct gctgctcacg
     3001 cccagtgctg tggtcattgt ggaggatgct aaagtcaagc agagaattga ttatgccaac
     3061 ctaaccggaa tctctgtcag tagcctgagt gatagcctat ttgtgcttca cgtgcagcgt
     3121 gaagacaaca agcagaaggg agatgtggtg ctgcagagtg atcatgtgat cgagacacta
     3181 accaagacgg ccctcagtgc tgaccgcgtg aacaatatca acatcaacca gggcagcata
     3241 acgtttgcag ggggtccagg cagggacggc atcattgact tcacatcggg ctcagagctt
     3301 ctcatcacca aggctaagaa tggccacctg gctgtggtgg ccccacggct gaattctcgg
     3361 tgatgaaggc ttcagtggac ccctcctgac tcctgatgct tcgcttagtc ccctcctccc
     3421 ctcccagtta ccaaagactc aagcttccag acagggatcc atggacaccc tcaaaaccca
     3481 cctgcaaact cctgcctcct gctcgccccc tctcgaggtg atcaggagcc agggagctac
     3541 cccatgagtg ggccaggccg ggccacagca atagaaaagc agaggcctga gcaggccagg
     3601 ccagccctct gctgatgcca aatatctaag agaagggaat tttaactgag gttttctctg
     3661 agattttttg atgctttata ggaaactatt tttttaagaa agccattttc ctaccctaaa
     3721 cacactggat gtgtttttcc ctgcctcgaa cagggcaagg aatgtaactg aaagactgac
     3781 tgggctgggc tggaaggtcc tcttctctgg ccaagcctct cctcattccc ttgtctgtct
     3841 gtccatccac ctgcaccttt tgcagcccac tatgacctcc accaaaaggc tgaggccacc
     3901 tctgcctacc ccatattcct gccttaagaa tgtcctttta ggggctgggg tatagcccag
     3961 tggtagaact ggtgctaagc atgtgtgaga ccctgggctc aatccccagc attaaaaaat
     4021 aaaaaatagg tttttaatat tttcacccca gtctgagggc atccctaaag tgggggaaaa
     4081 gtcttaagag tttggaagtc ttcagagaca gtgtctggtc caggctcctg gaatctacag
     4141 agctggagac agaggcacac agagggaggg aagacttgcc tagtagaaga ctgaagcaaa
     4201 tcctaaagtg aagcccgccc tcagcacatc tcactgcctt tcccagggac agggaggccc
     4261 ataaggcaag ggtcgcgtct catgtatgca cctggctctc tgaccagcaa tcacccttgg
     4321 gagctaccgg gtgggaggga ctcttctgcc tgggtctatg ccttaggatg acaacctcca
     4381 tacacataca tactttcgac ccaatttaag aatggtaggg tcttttattg gccttgggtg
     4441 cctctgtgac ctgggagcct agggacaggg ctggccttgg aggaactgca ggggcatcac
     4501 ctctttctgc tgcttctctc caccccagag gtccttgggt ttgcccagct ccctctgtgc
     4561 cctctggggc tctcagccca ctgctgacac ttctgcaatc cagagaaaca ctaaataaag
     4621 caatatgtat ttgccaacac agtcttcctg tgagtgtgga aaaggggccc tagaaggtag
     4681 acattcttaa ggggcttggc actacagaag aaaggagaca gacctactta ggagcaatag
     4741 agagaaacca agttaggtgt ggtattgtga gccttagtgc tcaggaagca gggacaggag
     4801 gattggattt cttagttcta ggccagcctg gtctacaaat caagttccag ggctatatag
     4861 acaggcacgg ggctttggat ttgggcaaat aaatacctgg tctggcagca ccgctggact
     4921 aaggagacct agcatgggca atataagccc aggggcctgt gctgatgcaa gactcaggtg
     4981 gggagggtca gcacttcata aggaagctgg tgtttgaggt atctcagggg cttgcttcca
     5041 gttctgggga taaagaatcc agtccaaagt ggctggagcg gtaaaggcca cttgtcaaca
     5101 atggccattt tattgtcctg gggagatcta cttctaggtg atcaaaagac attgttagga
     5161 aaatgtcttg ggggctagag agatggctca gtggttaaga gaactgactg ctcttctgaa
     5221 ggtcctgagt tcaattccca gcaactacac ggtggctcac aaccatctgt aatggggtct
     5281 gatgccttct ggtgtgtcta aagggagcaa tggtgatgta ctcatatgca taaaataaat
     5341 gaataaataa a
//
