LOCUS       NM_025414               4069 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus myosin XIX (Myo19), transcript variant 1, mRNA.
ACCESSION   NM_025414
VERSION     NM_025414.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Jiao,H., Jiang,D., Hu,X., Du,W., Ji,L., Yang,Y., Li,X., Sho,T.,
            Wang,X., Li,Y., Wu,Y.T., Wei,Y.H., Hu,X. and Yu,L.
  TITLE     Mitocytosis, a migrasome-mediated mitochondrial quality-control
            process
  JOURNAL   Cell 184 (11), 2896-2910 (2021)
   PUBMED   34048705
REFERENCE   2  (bases 1 to 4069)
  AUTHORS   Jones,M.R., Dilai,S., Lingampally,A., Chao,C.M., Danopoulos,S.,
            Carraro,G., Mukhametshina,R., Wilhelm,J., Baumgart-Vogt,E., Al
            Alam,D., Chen,C., Minoo,P., Zhang,J.S. and Bellusci,S.
  TITLE     A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b
            Signaling on Epithelial Tip Progenitor Cells During Early Mouse
            Lung Branching Morphogenesis
  JOURNAL   Front Genet 9, 746 (2019)
   PUBMED   30728831
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4069)
  AUTHORS   Lu,Z., Ma,X.N., Zhang,H.M., Ji,H.H., Ding,H., Zhang,J., Luo,D.,
            Sun,Y. and Li,X.D.
  TITLE     Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular
            motor
  JOURNAL   J Biol Chem 289 (26), 18535-18548 (2014)
   PUBMED   24825904
  REMARK    GeneRIF: Myo19 is a high-duty ratio molecular motor moving to the
            plus-end of the actin filament.
REFERENCE   4  (bases 1 to 4069)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645623.13, BC060115.1, CA749671.1, BU613548.1, AK080117.1 and
            AK018609.1.
            
            On May 3, 2018 this sequence version replaced NM_025414.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AL645623.13        39165-39214
            51-432              BC060115.1         1-382
            433-1157            CA749671.1         1-725
            1158-1389           BU613548.1         203-434
            1390-3974           AK080117.1         1059-3643
            3975-4069           AK018609.1         1955-2049
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 51.34 cM"
     gene            1..4069
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /note="myosin XIX"
                     /db_xref="GeneID:66196"
                     /db_xref="MGI:MGI:1913446"
     exon            1..342
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            343..484
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             473..3364
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     myosin head domain containing 1; myosin head
                     domain-containing protein 1; unconventional myosin-XIX"
                     /codon_start=1
                     /product="unconventional myosin-XIX isoform 1"
                     /protein_id="NP_079690.2"
                     /db_xref="CCDS:CCDS48871.1"
                     /db_xref="GeneID:66196"
                     /db_xref="MGI:MGI:1913446"
                     /translation="MLQQVNGHSLGSDAEGRASLKGDLREFLGGEIPLHQLDDLTKVN
                     PVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHVPQLYAPELMQEYHAAPQPQKL
                     KPHIFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCE
                     NHKIAERIEQRILNSNPVMEAFGNACTLRNSNSSRFGKFIQLQLNRAQQMTGAAVQTY
                     LLEKTRVACQASSERNFHIFYQICKGATKDERLQWHLPEGTAFSWLPNPESSLEEDCF
                     EVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEALPCQVMDDTKVSVRTS
                     ALLLQLPEKMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLV
                     SVINSSICADSKSWTAFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQ
                     QEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIES
                     TLAGRPCLGHNKLSREPSFVVVHFAGPVRYHTAGLVEKNKDPVPPELTELLQQSQDPL
                     LTMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHNTTPHYIRCIKPNS
                     QSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFIERYKLLRRLGPRMSSG
                     LGGLEPAEGSSEQPLCAKEATLQPLLQDILHALPALIQTAATPSDPAKNTQIPLYCGR
                     TKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVLIQAAFRSWL
                     TRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKPMPQAPGTLRSSMSPAHT
                     RFLGAIIHLWPLGLVLANSADGVRGFQRKLVAHACLRLPSDRPSNKVQTPQQDQAGIT
                     SIRALPQGSIKFHCRKSPLQYADICPDPSASCVTGFNQILLESHRPVQV"
     exon            485..623
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            624..772
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            773..886
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1019
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1089
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1192
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1289
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1366
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1457
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1629
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1703
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..1825
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1939
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2116
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2117..2269
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2270..2377
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2378..2448
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2449..2552
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..2719
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2720..2849
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2850..2935
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2936..3235
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3236..4069
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3937..3942
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /note="hexamer: AATAAA"
     polyA_site      3965
                     /gene="Myo19"
                     /gene_synonym="1110055A02Rik; Myohd1"
                     /note="major polyA site"
ORIGIN      
        1 agaactcggg aggccacgga aacgccacac ctcacacccc ggactcaata gacctcacct
       61 cgcgaacagc ccgctagccg gagccggcgg cctgggacgg gccacgtgcg tcccgcgccg
      121 cgtgtgcacg ccccgcccct ggggaggagc cggcgggctc cgggccatcg agccgcggtt
      181 gcagtgctcc gccaggcggc ctggagctcc cggctttctc tcccggccgc tcccgcgctc
      241 tctctcctcc acgggctctt cccgctgcct caccctgccc acccgccctt ccaatcggcc
      301 tgggctggga ctaccacgct gggcgcccgg gccgtgggac cggtttcaag atgactcggc
      361 tgcgattccc acactcctga gtcttctgct ggaaggatgg cctcatgacc aggttgacag
      421 acagcactct gtgtcggtga cacagaactc tggccgacca cactgaagca cgatgctcca
      481 gcaggtgaat ggccacagtt taggctctga tgccgaaggt agggcctccc tcaagggaga
      541 cctaagggag ttcctgggtg gggagatccc actgcaccag ctggatgacc tcaccaaggt
      601 gaatcccgtg acactggaaa cagtcctgag gtgcctgcag gcccgataca cagaagacat
      661 attctatacc aatgctggct gtaccttggt agctctgaac ccctttaagc acgtccctca
      721 actctatgca ccagaactga tgcaagagta ccatgctgca cctcagcctc agaaattgaa
      781 accccacatc ttcacagtgg gtgaacaaac ctatagaaat gtcaagagcc tgattgagcc
      841 ggtcaaccag tccatcgtgg tcagtggaga gagtggagcc ggaaagacat ggacatcccg
      901 atgcctgatg aagttctatg cggtggtggc tgcctcaccg acttcctgtg agaaccataa
      961 gattgcagag aggattgaac agcggattct gaactccaac cctgtgatgg aagcttttgg
     1021 gaacgcatgc acactgagga acagcaacag cagccgcttc gggaagttca ttcagctcca
     1081 actcaacaga gcccagcaga tgacaggagc tgcagtccag acctacctcc tagagaaaac
     1141 ccgtgtggcc tgtcaggcct ccagtgagag gaactttcac atcttctacc agatttgcaa
     1201 aggagccacc aaggatgaaa ggctccaatg gcacctccct gagggaactg ccttctcctg
     1261 gctacccaat ccagaaagca gtttggaaga ggattgtttc gaggtgacca gagaggccat
     1321 gctccatttg ggcatcgaca cccccaccca gaacaacatc tttaaggtcc tagctggact
     1381 gctgcacctt ggcaatgtcc attttgttga ctcagaggat gaagccctgc cctgccaagt
     1441 gatggatgat accaaggtct ctgtgaggac ctcagccttg ctgctgcagc tcccagagaa
     1501 aatgctgctg gagagtatgc agattcgaac catcaaggca ggcaagcagc agcaggtgtt
     1561 ccagaagccc tgctcccgag ccgagtgtga cacacgcaga gactgtctgg ccaaactgat
     1621 ctatgcacgg ctgttcgact ggctggtgtc tgtgatcaac agcagcatct gtgcagactc
     1681 caaatcatgg actgccttca tagggctgct agatgtgtat gggtttgagt catttcctaa
     1741 taacagtttg gaacagctgt gcatcaacta tgccaatgag aagctacagc agcacttcgt
     1801 ggctcactac ctcagggccc agcaggagga gtacgaagtt gagggcctgg agtggtcatt
     1861 tgtcaactac caggacaacc agacctgctt agatctcctt gaagggagcc ccatcagcat
     1921 ctgttccctc ataaatgagg aatgccgcct taaccggcca agcagtgcag cacaactaca
     1981 gacgcgcatc gagagcacgc tggcaggacg gccctgcctg ggccataaca agctcagccg
     2041 ggagcccagc ttcgtggttg tgcatttcgc gggacctgta cggtaccaca cagccggcct
     2101 ggtggaaaag aacaaggacc ctgttccccc tgagctgact gagctcctgc agcaatccca
     2161 agaccccctg ctcacgatgc tgtttcctgc caaccctgaa gagaagaccc aggaggagct
     2221 gtctggccag agccgggctc ctgcattgac tgtggtgtcc aagttcaagg cctcactgga
     2281 acagctcctg caggtcctac ataatacaac accccactac attcgctgca tcaagcccaa
     2341 cagccagagt cagccacaga ctttcctcca agaagaggtc ctgaaccagt tagaggcctg
     2401 tggccttgtg gaaaccattc acatcagtgc tgctggcttt cccatccggg tctctcacca
     2461 gaacttcata gaaagatata aactactgag aaggctcgga cctcgcatgt cctctggcct
     2521 cgggggcctg gagcctgccg aagggtcctc tgagcagcct ctgtgtgcca aggaggccac
     2581 actgcaacct ctactacagg acattctcca tgctctgcca gctttaattc agacagcagc
     2641 cactcccagt gacccggcta agaacacaca aatcccactg tactgtggca ggacaaagat
     2701 cttcatgact gactccatgc tagagcttct ggaatgtggg cgtgcccaga tgctggagca
     2761 gtgtgcccgt tgcatccagt gtggctggag gcgacaccgg ctccaaaagc aggagaaaca
     2821 gaggcgggct gccgtgctca tccaggctgc ttttaggtcc tggttaactc ggaaacacat
     2881 cagaaggtta cacatagctg ccacggtcat caagcacgca tggcataagt ggagaatcag
     2941 aatggcctgt cttgcctcta aagaactgga tggtatggag gagaaaccca tgcctcaggc
     3001 tcctggtacc ctgcggtcct cgatgtcccc agcacacact aggttcctgg gagcaataat
     3061 ccatctctgg cccctgggac tggtgctagc caactcagct gatggcgtac gtggctttca
     3121 gaggaaactg gtagcccatg cctgccttcg gcttccctca gacagaccca gcaacaaagt
     3181 ccagacacca caacaggatc aggctggtat tacatctatc agagcactgc cccagggctc
     3241 gataaagttt cactgcagga agtctccact tcagtatgct gacatctgcc ctgacccttc
     3301 agcctcctgt gttactggct ttaatcagat tctgctagaa agccacaggc cagtccaagt
     3361 gtgactcttc tacccccacc tgcctgagtg atctttagtg cctttgtttc cacaaggcct
     3421 tttcctgcca gctgtcttgc caaagacatt agatcccaca cgcaagtgcc aagctattcc
     3481 cacggcgact ccaactgcac gtgcaagcaa attccagcct gagccagggc ttcatggcca
     3541 gagtgccagc cttccagggc tgtggcttca gcactggcag gatctggggg tgctgggtac
     3601 caagccagga ttagggccac aacatcccag cttagtatct ttgtgctcaa gctccatcca
     3661 gaatgttgtc actacagcaa gatggatact gggccatcca caagcacttt aaaagggcca
     3721 agtcacccta aaattgcctc tagaattttg gctgggggag aacttgcata tagtttacta
     3781 agggaacaat aatatttaat aaactgattt atttaatgtt accaagaaca atgaacaatg
     3841 cagcatcaag agaaccacac cttaaattgt tacactatgt ttttaattca aatggatata
     3901 cttggtattt atgatgcaac tctgaactgt acaagaaata aaatttagaa ccatctaaat
     3961 ataaatagcc aaccttttgt ttttgtttta agtattttat gtatgtagga gttttccctg
     4021 tacatatggc tatgcacatg catacagtaa agactgtcag atcctctgc
//
