LOCUS       NM_001103171           11715 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus myosin XVA (Myo15a), transcript variant 3, mRNA.
ACCESSION   NM_001103171
VERSION     NM_001103171.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 11715)
  AUTHORS   Underhill,A., Webb,S., Grandi,F.C., Jeng,J.Y., de Monvel,J.B.,
            Plion,B., Carlton,A.J., Amariutei,A.E., Voulgari,N., De Faveri,F.,
            Ceriani,F., Mustapha,M., Johnson,S.L., Safieddine,S., Kros,C.J. and
            Marcotti,W.
  TITLE     MYO7A is required for the functional integrity of the
            mechanoelectrical transduction complex in hair cells of the adult
            cochlea
  JOURNAL   Proc Natl Acad Sci U S A 122 (1), e2414707122 (2025)
   PUBMED   39746042
REFERENCE   2  (bases 1 to 11715)
  AUTHORS   O'Connor,A.P., Amariutei,A.E., Zanella,A., Hool,S.A., Carlton,A.J.,
            Kong,F., Saenz-Roldan,M., Jeng,J.Y., Lecomte,M.J., Johnson,S.L.,
            Safieddine,S. and Marcotti,W.
  TITLE     In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic
            efferent innervation in inner hair cells
  JOURNAL   JCI Insight 9 (23), e182138 (2024)
   PUBMED   39641274
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 11715)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 11715)
  AUTHORS   Li,J., Choi,B.Y., Eltawil,Y., Ismail Mohamad,N., Park,Y.,
            Matthews,I.R., Han,J.H., Kim,B.J., Sherr,E.H. and Chan,D.K.
  TITLE     TMTC4 is a hair cell-specific human deafness gene
  JOURNAL   JCI Insight 8 (24), e172665 (2023)
   PUBMED   37943620
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 11715)
  AUTHORS   Cortada,M., Levano,S., Hall,M.N. and Bodmer,D.
  TITLE     mTORC2 regulates auditory hair cell structure and function
  JOURNAL   iScience 26 (9), 107687 (2023)
   PUBMED   37694145
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 11715)
  AUTHORS   Webster,D.B., Sobin,A. and Anniko,M.
  TITLE     Incomplete maturation of brainstem auditory nuclei in genetically
            induced early postnatal cochlear degeneration
  JOURNAL   Acta Otolaryngol 101 (5-6), 429-438 (1986)
   PUBMED   3727977
REFERENCE   7  (bases 1 to 11715)
  AUTHORS   Weimar,W.R., Lane,P.W. and Sidman,R.L.
  TITLE     Vibrator (vb): a spinocerebellar system degeneration with autosomal
            recessive inheritance in mice
  JOURNAL   Brain Res 251 (2), 357-364 (1982)
   PUBMED   7139332
REFERENCE   8  (bases 1 to 11715)
  AUTHORS   Anniko,M.
  TITLE     Specific pathology of the stria vascularis in postnatal progressive
            genetic inner ear disorder
  JOURNAL   Hear Res 6 (3), 247-258 (1982)
   PUBMED   6979536
REFERENCE   9  (bases 1 to 11715)
  AUTHORS   Sobin,A., Anniko,M. and Flock,A.
  TITLE     Rods of actin filaments in type I hair cells of the Shaker-2 mouse
  JOURNAL   Arch Otorhinolaryngol 236 (1), 1-6 (1982)
   PUBMED   6889851
REFERENCE   10 (bases 1 to 11715)
  AUTHORS   Kelton,D.E. and Rauch,H.
  TITLE     Linkage of open eyelids with linkage group VII of the mouse
  JOURNAL   J Hered 59 (1), 27-28 (1968)
   PUBMED   5690495
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY331132.1, AL596090.11 and AL596386.16.
            
            Transcript Variant: This variant (3) lacks an in-frame exon in the
            5' coding region, compared to variant 1, resulting in a shorter
            protein (isoform 3), compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY331132.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3709              AY331132.1         1-3709
            3710-3710           AL596090.11        201345-201345
            3711-4512           AY331132.1         3711-4512
            4513-4513           AL596386.16        4350-4350
            4514-7071           AY331132.1         4514-7071
            7072-7072           AL596386.16        18503-18503
            7073-9092           AY331132.1         7073-9092
            9093-9093           AL596386.16        25729-25729
            9094-9818           AY331132.1         9094-9818
            9819-9819           AL596386.16        33558-33558
            9820-10579          AY331132.1         9820-10579
            10580-10588         AL596386.16        42640-42648
            10589-10954         AY331132.1         10589-10954
            10955-10955         AL596386.16        43678-43678
            10956-11715         AY331132.1         10956-11715
FEATURES             Location/Qualifiers
     source          1..11715
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.81 cM"
     gene            1..11715
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /note="myosin XVA"
                     /db_xref="GeneID:17910"
                     /db_xref="MGI:MGI:1261811"
     exon            1..88
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            89..3850
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     CDS             290..10771
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     unconventional myosin-15; shaker 2; unconventional
                     myosin-XV"
                     /codon_start=1
                     /product="unconventional myosin-XV isoform 3"
                     /protein_id="NP_001096641.1"
                     /db_xref="CCDS:CCDS48811.1"
                     /db_xref="GeneID:17910"
                     /db_xref="MGI:MGI:1261811"
                     /translation="MADEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKI
                     SKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPS
                     FMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRS
                     SSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRK
                     SLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAEFGGYSPAWPPYDDYGY
                     PPGDPYNYYHPDYYGDTLYPGYAYGYGYGYDDFEPPYAPPSGYSSPYSYHDSFESEAY
                     PYSYYLDPYATHHMPYPPYDFPYDTPYDIPYFDPYGVPYAEGVYGGGAEAIYPPGMPY
                     VYPEEPAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEETGEERQSTSFRLPSAAFFE
                     QQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEE
                     EMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLGFGPEFGHPTPRPATSLARF
                     LKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQP
                     QARNNNNSHGPPSPRPAPRALTHWSALISPPMPAPSPSPASPLTPPFSPTFSRPPRLA
                     SPYGSLRQHPPPWAAPAHVPFPPQANWWGFAEPPGTSPEVAPDLLAFPVPRPSFRASR
                     SRSRRAAYGFPSPSLIGSRRRPHLPSPQPSLRSLPGQGYHSPLGPLSPQLSLRRGPFQ
                     PPFPPPPRRPQSLREAFSLRRASGRLGPPRSPVLGSPRPPSPPPLLKHGPRHRSLNLP
                     SRLPRTWRRLSEPPTRAVKPWVHRAYPPPPSAGPWGASTGALEQQENQREAEDSETPW
                     TVPPLAPSWDVDMPPTQRPPSPWPEGIGSLRGFSRPPPVPENPLLEHTSPSCEPQSED
                     RVSNLTGIFLGQHHDPGPGQLTKSADPSLEKPEEVVTLGDPQPPAEPEALNPTPPNKN
                     VVSERKVLRLSASYPLVTCKQARATWPQWHRWKTVSRTPAPLAPTRAPGPLLKAGEQP
                     RAEPGRFAVVMPQVRGVSSFRPKGPAPVQPPEHPDQDPEQGPAPQACSLRWPRLWPPT
                     DAHCLWSRIRTYSSQSHLRGHGGDCHKSLWKKTRPQSWQNKMHSIRNLPSMRSREQHR
                     EDGVEDMTQLEDLQETTVLANLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQ
                     YSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLILRCLAAMN
                     QRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLL
                     EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDA
                     DDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQ
                     AVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLI
                     TRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQE
                     EYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHG
                     ANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHL
                     FSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNH
                     KKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPAD
                     GDMCVSLLSRLCTVTPDMYRVGISKLFLKEHLHQLLESMRERVQNRAALTLQRYLRGF
                     FIQRHFRSLRRKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKELSK
                     REVVPVRHLEVPAEVAGLLQAAAGLKLSSGPRVAVVRAPRLQAEPCVTLPLDINNYPM
                     AKFIRCHFKEPSFGMLTVPLKMPLTRLPVEHHAEAISVFKLILRFMGDPHLHGTQEMI
                     LGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNSKRGWLLLAACLSGFAPSPHLDK
                     FLLKFVSDYGQNGFQAVCQHRLLQAMGSGAARTFPPTQLEWTAIQEKASMALDVSCFN
                     GDQFSCPVHTWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVS
                     DLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPD
                     LDGYCSHKEDGTNGETEAQRWTSNRQAVDSIGESTVPPRELDGYLDSLFDPVLACGDA
                     DLEKPTAIAYRMKGGGQPGGGGGSTSEDTSRRPPEPKLKPIPGLDASTLALQQAFIHR
                     QAVLLAREMTLQALALQQQPLSATSRPQLPERPLAPEARPKTVVGTGPPAKPVLVRPT
                     PQSWAPGSVAKAPKIPSKPVAVPILAQDWTAPESISASPELVRYSTLNSEHFPQPTQQ
                     IRSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVS
                     REAVAMVKPVTSAPRPCMGPTPVQPSRSLEPPEDPVQTQLHRLVNPNFYGYQDIPWRI
                     FLRKEVFYPKDNYSHPVQLDLLFRQILHDTFSEACLRISEDERLQMKALFAQNQLDTQ
                     RPLVTESVKRAAISMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGIKLLQMVKGSK
                     EASRRLRVLCAYSFADILFVTMPSQNMLEFNLSNEKLILFSARAQQVKTLVDTFILEL
                     KKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPTRVGYSAGCVVRKKLVYLEELR
                     RRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAA
                     QEVGRRREGPPVRARSADSGEDSIALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDR
                     ESKTLEDVLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLKGQSELDVLC
                     TLLKLCGDHEVMRDECYCQIVKQITDNSSPKQDSCQRGWRLLYIMAAYYSCSEVFYPY
                     LIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSNMELRAMLAGRSSKRQL
                     FLLPGGLERHLKIKTCTVALDVIEGLCTEMALTRPEAFDEYVIFVVTNRGQHVCPLSC
                     RAYILDVASEMEQVDGGYTLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLFSSV
                     PARQPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLYHTTAGDTWLNLVSQ
                     HRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSNVLVPAPCILAVNHNGLNFL
                     STKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCR
                     VVAVHVESMLSAREERLTLPPSEITLL"
     exon            3851..3933
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3934..3997
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            3998..4107
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4108..4182
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4183..4273
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4274..4279
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4280..4383
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4384..4447
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4448..4561
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4562..4723
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4724..4837
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4838..4896
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            4897..5020
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5021..5116
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5117..5248
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5249..5374
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5375..5452
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5453..5601
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5602..5647
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5648..5772
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5773..5890
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            5891..6066
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6067..6151
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6152..6233
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6234..6364
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6365..6460
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6461..6696
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6697..6860
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6861..6933
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            6934..7125
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7126..7286
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7287..7381
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7382..7502
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7503..7570
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7571..7648
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7649..7832
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7833..7965
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            7966..8071
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8072..8144
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8145..8266
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8267..8326
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8327..8402
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8403..8518
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8519..8637
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8638..8779
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8780..8891
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8892..8966
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            8967..9145
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9146..9261
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9262..9334
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9335..9407
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9408..9481
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9482..9564
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9565..9695
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9696..9790
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9791..9868
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9869..9965
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            9966..10126
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            10127..10260
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            10261..10394
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            10395..10528
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            10529..10669
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
     exon            10670..11715
                     /gene="Myo15a"
                     /gene_synonym="Myo15; sh-2; sh2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcctgagcc tcctttccat ctctgtggag gcagacatag gacccccaac aaacagcatg
       61 caggttggga gccagccaca ggacccaggt gaaacccaag gctggtctag agaatgaatt
      121 atggatcctc gctgtccgtg ccacccagct agtcccagcg gctcagacac tgaggagaga
      181 ctgtaggttc agctacaagc aaaaagacct agctggtctc caagcagtgt ctccaagtcc
      241 ctgaacctgt gacacctgcc ccaggcatca tcaggcacag agggccacca tggcggatga
      301 ggagaagaaa gcgaagaaag ggaagaaggg gaagaaggcc ccagagcctg agaaacccaa
      361 acggagcctc aagggcacat ctcggctctt catgggcttc cgagaccgca cgcccaagat
      421 ctctaagaaa ggtcagttcc gaagtgcatc agccttcttc tggggcctcc acactggccc
      481 gcagaagacc aagcgcaaga agaaggcccg tactgttctc aaatccacat ccaaactcat
      541 gacgcagatg cgggtgggca aaaagaagcg ggcgatgaag ggaaagaagc cctcgttcat
      601 ggtgatccgc ttccctggac ggcgcggcta tggccgcttg aggcctcgtg cccagtcact
      661 tagcaaggca tccacagcta ttaactggct gaccaagaag ttcctcctca agaaggccga
      721 agagtcaggc agtgagcagg ccacagtgga cgcctggctc cagcgctcca gctcccgagt
      781 tggctcacgt aagctgccct tcccgtcggg tgctgagatc ctgcggcatg gaggccggct
      841 ccgcaggttc ccccgcagtc atagcatcta ctcctccgga gagcccgtgg gcttcctgcc
      901 ctttgaggac gaagccccat ttcggcacgc aggctcccgc aagtcattgt atgggctcga
      961 gggcttccag gacctgggtg aatattacga ctaccatcgg gaaggcgacg actactatga
     1021 ccagcagtcg ctataccact acgaggagca ggagccctac ttggctgagt tcggtgggta
     1081 tagcccggcc tggccaccct atgatgacta tgggtaccca cccggagacc cgtacaacta
     1141 ctaccaccct gactactacg gtgacaccct ctaccctggc tatgcctatg gctatggcta
     1201 cggctacgat gattttgagc ccccatatgc gcccccatca gggtattcat cgccttacag
     1261 ctaccatgac agctttgaga gtgaggccta cccatacagc tactacctgg acccctatgc
     1321 aactcaccac atgccctatc caccctatga ctttccatat gacactcctt acgacatacc
     1381 ctactttgat ccttatgggg ttccctatgc tgaaggtgtc tatggcggtg gggccgaggc
     1441 catctatccc cctgggatgc cctatgtcta tccagaagag ccagctttta tgtacccatg
     1501 ggtgccgcca cccataatgt cgccccacaa cccatatgcc caccccatgg acgacattgc
     1561 cgagctggag gagcctgagg aaacaggtga agaacgtcag agcacctcct tccgcctgcc
     1621 cagtgccgcc ttcttcgagc aacaaggtat ggacaaacca gccaggtcca aactatccct
     1681 catccggaag ttccgcctct tcccacggcc tcaggtgaag ctgtttggga aagagaagct
     1741 agaggtgccc ctgccaccct ccctcgacat tcctctgcct ttaggggatg cagagggtga
     1801 ggaagaggag gaggaaatgc ccccagtgcc cacgatgccc tacacccacc cttactggag
     1861 cttcctcaca ccgcgccagc gaaacctaca gcgcgccctg tcagcctttg gtgcccgcca
     1921 aggcctaggc tttggccctg agtttggcca cccaacgcca cgcccagcca cctcactggc
     1981 acggttcctc aaaaaaacac tgtcagaaaa gaagcccatt ccacggctca ggggcagcca
     2041 gaaggcccga ggagggcggc ccccagtgag ggaggcagcc tacaaacgct ttggctacaa
     2101 gctggccggc atggaccccg atcgacccaa cacgcccatt gtgctgagac gaagtcagcc
     2161 acaagctcgc aacaacaaca actcccacgg gccaccgtca cccaggcctg caccaagggc
     2221 actcacgcac tggagtgctc tcatctctcc tccaatgcct gcgccatctc ccagccccgc
     2281 ctctccattg accccaccct tctctccaac cttctcccgg cctccaaggc tagcttcccc
     2341 ctatggctcc ctccgccagc atccaccacc ctgggctgcc ccagctcatg tgccttttcc
     2401 accccaggca aattggtggg gctttgctga accccctgga acaagcccag aggttgcgcc
     2461 tgaccttctg gcctttcctg taccccggcc ctcgttcagg gcttcccgca gtcgcagtcg
     2521 gagggcagct tatggtttcc ccagcccttc cctgatagga tccaggagaa ggccccacct
     2581 gccctcaccc cagccctctc tgaggagcct tccaggtcag ggctaccact caccactggg
     2641 accgttgtct cctcagttgt ccctccgaag gggtcctttc cagccaccct tcccaccccc
     2701 tccacgcaga cctcagtcac tccgggaggc cttctctcta cgtagagcct ctgggcgcct
     2761 gggcccaccc cgctcaccag tgctaggttc tccccgacca ccctcaccac ccccactcct
     2821 gaaacacggc ccccggcacc ggtccctcaa cctgccctca cgccttccac ggacctggcg
     2881 gcgcctcagc gagcctccta cgcgggctgt gaaaccatgg gtacataggg cgtacccccc
     2941 accacccagt gccgggccct ggggggcatc cacgggggct ttggagcagc aagagaacca
     3001 acgtgaagca gaagactcag aaacaccgtg gacagttccc ccattggccc ccagctggga
     3061 tgtggatatg cctcccacac aacgcccacc ttctccgtgg ccagaaggta taggcagcct
     3121 tagaggcttc tccaggcccc ctcctgtgcc tgaaaatcca ttgcttgagc acacaagccc
     3181 ttcatgtgag ccacagtctg aggaccgagt ctctaattta actggtatct tcctgggcca
     3241 acaccatgac ccagggcctg ggcaactcac caagtcagcc gacccaagct tggagaagcc
     3301 tgaagaagtg gtcaccctag gggaccctca gccaccagct gagcctgagg ccctgaaccc
     3361 aacacctccc aacaaaaatg ttgtctcgga gaggaaggtt ttacgactca gcgcctcgta
     3421 cccactggtc acatgtaagc aggcaagggc aacatggcca caatggcacc gctggaagac
     3481 agtgtctaga actccagctc ccttggcccc caccagagcc ccagggccct tgctcaaggc
     3541 tggtgagcag ccccgggcag aacctgggcg gtttgcagtt gtcatgcctc aggtgcgtgg
     3601 ggtaagctcc ttccggccaa aagggcctgc tcctgtgcag cctccagagc atccagacca
     3661 agacccagag cagggcccag ccccccaagc ctgtagtcta cgctggcccc gcctctggcc
     3721 accaacagat gctcactgtc tctggtcacg aattcgcacc tactcctctc aatcccacct
     3781 ccggggccat ggaggtgact gtcacaagag cctctggaaa aagactcgcc cccaaagctg
     3841 gcagaacaag atgcactcca tacgcaacct gccttctatg cggtcccgtg agcagcacag
     3901 ggaagatgga gtggaggaca tgacgcagct ggaagacctc caagagacca ctgtgctagc
     3961 caacctaaag accagatttg agcgaaacct catctatacc tatattggca gtattctggt
     4021 gtcggtgaac ccatatcgaa tgtttgcaat ctacgggcct gagcaggtgc agcagtacag
     4081 tgggcgtgcc ctaggagaaa atcccccgca cctctttgca attgctaatc ttgccttcgc
     4141 caaaatgctt gatgccaaac agaaccagtg tgtcatcatc agtggggaga gtggctctgg
     4201 aaagactgag gctacgaaac tgattctgcg ctgcctggct gccatgaacc agagacggga
     4261 cgtcatgcag cagataaaga tcctggaggc aacgcctctc ctggaggcct ttggtaatgc
     4321 caaaactgtc aggaatgaca actccagccg ctttgggaag tttgtggaaa tctttctaga
     4381 agggggtgtg atctgtggtg ccataacctc tcagtacctg ctggagaagt caaggattgt
     4441 gttccaggcc aaaaatgaaa gaaattatca tattttctat gagctgctgg ctgggctccc
     4501 tgctcaacta aggcaggcct tcagcctgca ggaggctgag acctactact acctgaacca
     4561 gggcgggaac tgtgagatcg ctggaaagag tgacgcagat gacttccgcc gtctgctggc
     4621 tgcgatggag gtgcttggct tcaccagtga ggaccaggac agcatcttcc gaatcctagc
     4681 ctccatctta cacctgggca atgtctattt tgagaaacat gagaccgatg cccaggaggt
     4741 ggcctcggtg gtgagcgccc gggagatcca ggctgtggca gagctgcttc aggtctctcc
     4801 tgagggcctg cagaaggcta tcaccttcaa agtgactgag acaattcgag agaagatctt
     4861 cacaccccta acagtggaga gtgccgtaga tgccagggac gccatcgcca aggtcttgta
     4921 tgcactgctg tttggctggc tcatcaccag ggtcaacgct ctggtgtccc caaaacaaga
     4981 tacattgtcc atcgccatct tggacatata tggctttgag gacctgagct tcaacagctt
     5041 tgaacaactg tgcatcaact atgccaacga gaaccttcag tacctgttca acaagatcgt
     5101 cttccaggag gagcaggagg agtacatccg ggagcagatg gactggagag agattgcctt
     5161 tgctgacaac cagccctgca tcaacctcat ctccctgaag ccctacggca tcctgcgcat
     5221 cctggatgac cagtgctgct ttccccaggc cacagaccac acattcctgc agaagtgcca
     5281 ctaccaccat ggcgccaacc cgctctactc taagcctaag atgccactgc cagagtttac
     5341 catcaagcac tatgcaggca aggtcaccta ccaggtgcac aagttcctgg acaagaacca
     5401 tgaccaagtg cgccaagacg tcctggactt gtttgtgcac agccgcacaa gggtggtagc
     5461 acaccttttc tccagccacg ctgcgcagac tgcccctcca cgcctgggca agagcagctc
     5521 cattacccgt ctctacaagg ctcacacggt ggcggccaag ttccagcagt ccctcctgga
     5581 cctggtggaa aagatggaga ggtgtaaccc tttgttcgtg cgctgcctga agcccaacca
     5641 taagaaggaa cctggtctct ttgagccaga tgtgatgatg gcacagttac gctattcagg
     5701 ggttctggag actgtgagga tccgcaagga aggctttccg gtgcggctac ccttccaggt
     5761 gtttatcgac aggtaccggt gcctggtggc cctcaagctc aacgtgccag cagatgggga
     5821 catgtgtgtg tcattgctga gccggctatg cacggtcact ccagacatgt accgtgttgg
     5881 gattagcaag ctcttcctca aggagcacct gcaccagcta ctggagagca tgcgggagcg
     5941 agtccagaac cgagctgccc tcaccctgca gcgctacctg cgaggttttt tcatccaacg
     6001 gcacttccgg tccttgcggc ggaagatcat cctactgcag agcagagccc gtggttttct
     6061 ggccagacaa cgctaccagc agatgaggca gagtctgctg aagttccgtt ccctggtgca
     6121 cacctacgtg aaccgccgcc gctacctcaa ggagctgagc aagcgtgaag tggtcccagt
     6181 gagacatctg gaggtgccag ctgaggtggc tgggctcctg caagccgcag caggcctcaa
     6241 gctgtccagt gggccccgag tggctgttgt ccgggctcct aggctccagg ctgagccgtg
     6301 tgtcacactt ccccttgaca tcaacaacta ccccatggcc aagttcattc gatgccactt
     6361 caaggaaccc tcctttggga tgctgacagt gcccctgaag atgcctctca cacggctgcc
     6421 tgtggagcac cacgcagaag ccataagtgt ctttaagcta atcctgcgtt tcatgggaga
     6481 cccccacctg catggcaccc aagagatgat cttggggaac tacattgtgc accaggggct
     6541 ggtggagcca gctctgaggg acgagatcct agcccagctg gccaaccagg tgtggcgcaa
     6601 tcccaatgcc tacaactcca agcggggctg gttgctgttg gctgcctgtc tcagtggctt
     6661 tgcgccttcc ccgcaccttg acaagttcct cctcaagttt gtatctgatt atggacagaa
     6721 tggcttccag gctgtgtgcc agcatcgcct cctgcaggcg atgggctcag gggctgcccg
     6781 gacctttccc ccaactcagc tggagtggac tgccattcag gagaaggcca gtatggctct
     6841 agatgtgagc tgcttcaatg gtgaccagtt ctcctgtccg gtccacacct ggagtacggg
     6901 ggaagcggtg gctggagaca tcctaaagca cagggggctg gctgatggtt ggaggggctg
     6961 gacagtggcc atgaagaatg gagtccagtg ggcagagctg gctggacatg actatgtgct
     7021 ggacctggta tcagacctgg aactgctcag ggacttccca cgacagaaat cctacttcat
     7081 agtgggtgca gaagggcctt tggctggcag gggagacacc agaggagtgt ttgggaactg
     7141 ctgggactca gacgaggaca cacccacaag gccccagccc caggaccacg tggccaagat
     7201 gcctgacttg gatgggtact gcagccacaa agaggatggt acaaatggag aaactgaggc
     7261 ccagagatgg acatcgaacc gccaagctgt ggacagcatt ggagagtcca ctgtgccccc
     7321 cagggagctg gatggctact tggacagtct cttcgaccct gtgctggcct gtggggatgc
     7381 ggacctggag aagccgacag ccatcgccta ccgcatgaaa ggtgggggcc agccaggtgg
     7441 aggtggtggc agtacttctg aagatacctc ccggagaccc ccggaaccca agctcaagcc
     7501 catcccaggc ctggatgcct ccacactggc tctgcagcaa gccttcatcc acaggcaggc
     7561 tgtgctactg gcccgggaga tgaccctgca ggctttggca cttcagcagc agcctctgag
     7621 tgcaacctca agacctcagc tcccagagag acccctagca ccagaggcac ggccgaagac
     7681 tgtagtaggc actggccccc cagccaagcc tgtgctggtg cgtccgactc cacagtcgtg
     7741 ggctccgggc tctgtggcaa aggccccgaa gatacctagc aagcccgtgg ctgtcccaat
     7801 cctagctcaa gattggactg ctccagaatc catttcggct tcccctgagc tggttcggta
     7861 ttccacactc aactcagagc acttcccaca acccacacag cagatcagaa gcatcatcaa
     7921 gcaatacaaa cagccaccct gggcaggaca ccctgaggcc cgcaggacgg atggtggaaa
     7981 ggtcttcagg aggccacctg acccccatga ggaggcccta atgattctga agggacagaa
     8041 gactcaacta gcagtagtgc ctggcactca ggtgtccaga gaggctgtgg ccatggtgaa
     8101 gccggtgacc agtgctccaa ggccatgcat ggggcccact ccagtgcagc cttcaaggtc
     8161 gctggagcct ccagaggatc ctgtgcagac acagctgcac cgcctagtca accccaactt
     8221 ctatggctac caggacatcc cctggcggat cttcctgcgc aaggaggtat tttaccccaa
     8281 ggacaactac agtcaccctg tgcagctaga cctcctgttc cggcagatcc tgcatgacac
     8341 attctccgag gcttgcctgc gcatatctga ggatgagcgg ctgcagatga aggctctgtt
     8401 tgcccagaac cagctggaca cacagcgacc tctggtaaca gaaagtgtga agcgggccgc
     8461 catcagcatg gcccgagaca gctgggagat ctacttctct cgcctcttcc cggcaatggg
     8521 cagtgttggc accggcgtgc agatcctagc tgtgtctcac actggcatca agctcctgca
     8581 gatggtcaag ggcagcaagg aggccagcag gcggctccgc gtcctgtgtg catacagctt
     8641 tgcagacatc ctgtttgtaa ccatgccatc tcagaacatg ctagagttca atctgtccaa
     8701 cgagaagctc atcctcttct cagcccgggc gcagcaggtc aagaccctag tagacacctt
     8761 cattctggaa ctgaagaagg attctgatta tgttgtggca gtgaggaact tcctgtctga
     8821 agaccccgag ctgctgtcct tccacaaggg tgacatcatc cacctgcaga gcctggaacc
     8881 aactagagtg ggctacagcg ccggttgtgt agtccgcaag aaactggtgt acctggagga
     8941 gctgaggcgg agaggccctg actttggctg gaggttcggg gccgtccacg ggcgcgtagg
     9001 acgttttcct tcagagctcg tgcagcccgc agctgctcca gacttcttgc agctcccggc
     9061 agagccaggg cggggccggg ctgccgcggt ggccgccgct gtggcctctg cagcagccgc
     9121 acaggaggtg gggcgccgga gagagggtcc cccagtcagg gcgcgttccg ctgacagcgg
     9181 agaggattcc atagcgctcc caccgagcac aatgctcgaa tttgcccaga agtatttccg
     9241 agaccctcgg aggcgtcccc gggatggcct caagctgaag tctaaggagg atcgggagtc
     9301 caaaactctg gaggacgtgc tttgcttcac taaggtcccg atccaggaat ccctcattga
     9361 actcagtgac agcaatctca acaagatggc ggttgacatg tttgtagctg tgatgaggtt
     9421 catgggagat gccccactga agggccagag cgaactggat gttctctgca cccttctgaa
     9481 gctttgtgga gaccatgagg tcatgagaga tgaatgctac tgccagattg tgaagcagat
     9541 cacagacaac agcagcccta agcaggacag ctgtcagcga ggctggaggc tgctttacat
     9601 catggctgcc tactatagtt gctctgaggt cttctatcca tacctcattc gcttcctcca
     9661 acatgtgagc tggactcctg gcctgccctt ccaagggatt gccaaggcct gtgaacagaa
     9721 cctgcagaag accttgcgtt ttggaggccg cctggagttc cccagcaata tggagctccg
     9781 tgctatgttg gcaggccgca gttccaagag gcagctcttt cttcttccag gaggccttga
     9841 acgccatctg aaaatcaaaa cgtgcacggt ggccctggat gtcatagagg ggctctgtac
     9901 cgagatggcc ctgacacgcc ctgaagcctt tgatgagtat gtcatttttg tggtcaccaa
     9961 ccgaggccag cacgtgtgtc cactgagctg ccgggcctac atactggatg tggcctcaga
    10021 gatggagcag gtggacgggg gctacacact ctggttccgg cgggtgcttt gggatcagcc
    10081 actgaagttt gagaatgagc tgtatgtgac catgcactac aatcaggttc tgcctgacta
    10141 cctgaagggc ctctttagca gtgtgccggc caggcagccc acagagcaac aactacagca
    10201 ggtgtccaag ttggcttcac tgcagcaccg agccaaggac cacttctacc tgcccagtgt
    10261 gcgtgaagtc caagagtaca tcccagccca gctctaccac accacggccg gtgacacctg
    10321 gctcaacctg gttagccaac acaggcagca gactcaggcg ctcagtcccc accaggcccg
    10381 cgctcagttc ctgggcctcc tcagtgcctt ccccttgttt ggctcctcct tcttcttcat
    10441 ccagagctgc agcaatgtct tggtgccagc cccctgtatc ctcgctgtca accataacgg
    10501 cctcaacttc ctcagcacca agacccatga gttgattgtg aagattcccc tgaaggagat
    10561 ccagtccacg tggactcagc agcccacagc caattccagt tacccgtatg tggagatctc
    10621 cctgggggat gtggcagccc agcggaccat gcagctccag ctggagcagg gtctggagct
    10681 gtgtcgcgtg gtggctgtgc atgtggagtc catgctcagc gcccgggagg agcggctcac
    10741 actgcctccc agcgagatca ccctcttgtg acgtggccta ccttttcact gcttcccgcc
    10801 agaagatttg ctccatgccc tgagggtaga tgctcagcct ctccagacca agtgactctt
    10861 ggggtgctgg ggagatgact caacagttaa gaacattggc tggtgaaaaa aagaacattg
    10921 gctgtttttc cagggacctg ggttcaattc ctagcatcca cataacagct cacaaccatt
    10981 tgtaactcca gttctatgat gttgtccatg ggtaccaggt acacatgtga tgcagacata
    11041 tgtgcaggca aaatacctag acaagagcca gaaccttgga ggagaccaaa ggagacagga
    11101 ggaaaaactc aagaacccaa gaggaccaat ctggagctgg gatggagtta cgggtgcagc
    11161 caaggcttac ttagcagaag tggtttttaa aagctggacc acagggcctc cagaaggcag
    11221 agcctgcctt gacaactgcc cttgacaggg aagccccaca ctagtagttt agatgttttg
    11281 ggggctgcct ctggtttctt ggggcttgat actcagatct gctccggcgt cacactccag
    11341 ccttccgcat gtccttgcca ggtgccctca gctcagacct aggaccctta gtcatttctt
    11401 cacaagtatt tctggtctgt cctccgtgct gacagattga gtcagaatga ctttaaattc
    11461 aaaatcaact caggctacag agcaagaccc tgcctgaggg gaggggtgct ggggagatga
    11521 ctcaacagtt aagaacattg gctggtgaaa aaaagaacat tggctgtttt tccagggacc
    11581 tgggttcaat tcctagcatc cacataacag ctcacaacca tttgtaactc cagttctatg
    11641 atgttgtcca tgggtaccag gtacacatgt gatgcagaca tatgtgcagg caaaataccc
    11701 atatccataa ataaa
//
