LOCUS       NM_030557               5550 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus myoneurin (Mynn), transcript variant 1, mRNA.
ACCESSION   NM_030557
VERSION     NM_030557.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5550)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5550)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   3  (bases 1 to 5550)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   4  (bases 1 to 5550)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 5550)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 5550)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   7  (bases 1 to 5550)
  AUTHORS   Cifuentes-Diaz,C., Bitoun,M., Goudou,D., Seddiqi,N., Romero,N.,
            Rieger,F., Perin,J.P. and Alliel,P.M.
  TITLE     Neuromuscular expression of the BTB/POZ and zinc finger protein
            myoneurin
  JOURNAL   Muscle Nerve 29 (1), 59-65 (2004)
   PUBMED   14694499
REFERENCE   8  (bases 1 to 5550)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 5550)
  AUTHORS   Alliel,P.M., Seddiqi,N., Goudou,D., Cifuentes-Diaz,C., Romero,N.,
            Velasco,E., Rieger,F. and Perin,J.P.
  TITLE     Myoneurin, a novel member of the BTB/POZ-zinc finger family highly
            expressed in human muscle
  JOURNAL   Biochem Biophys Res Commun 273 (1), 385-391 (2000)
   PUBMED   10873615
REFERENCE   10 (bases 1 to 5550)
  AUTHORS   Agata,Y., Matsuda,E. and Shimizu,A.
  TITLE     Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc
            finger proteins by degenerate PCR
  JOURNAL   Gene 213 (1-2), 55-64 (1998)
   PUBMED   9630514
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC065084.1, AC120377.25 and BF465039.1.
            
            On Jan 24, 2014 this sequence version replaced NM_030557.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065084.1, AK136107.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4157              BC065084.1         1-4157
            4158-5378           AC120377.25        85286-86506         c
            5379-5550           BF465039.1         1-172               c
FEATURES             Location/Qualifiers
     source          1..5550
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 14.27 cM"
     gene            1..5550
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="myoneurin"
                     /db_xref="GeneID:80732"
                     /db_xref="MGI:MGI:1931415"
     exon            1..609
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            610..906
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     CDS             641..2473
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="myoneurin isoform 1"
                     /protein_id="NP_085034.2"
                     /db_xref="CCDS:CCDS17284.1"
                     /db_xref="GeneID:80732"
                     /db_xref="MGI:MGI:1931415"
                     /translation="MQYSHHCEHLLERLNKQREAGFLCDCTVVIGEFQFKAHRNVLAS
                     FSEYFGAIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYL
                     KVEEVVTKCKIKMEDFAFIASPSSTEISSITGNIELNQQACLLTLRDYNNREKSEVST
                     DSVQANPKPRALTKKSSQSKKKKKAFSSQKPGQSKAVQYPSDVLESASVELFLETSKL
                     SSPVVEQIIQGNDSSELELTSVVENTFPTQDIVQTVTVKRKRRKSQSHCALKEHSMSN
                     IASVKSPYELENAGEELDARFSKAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHL
                     CGKAFTQCNQLKTHVRTHTGERPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVC
                     NLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGK
                     AFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGERPFICELCGNSY
                     TDIKNLKKHKTKVHSGTDKNPDCSVDDHAVSEQDSVQRSPLSETLDVKPSDMTLPLAL
                     PLGTEDHQMLLPVTDSQSPASDTLLRSTVNGYSEPQLIFLQQLY"
     exon            907..1700
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            1701..1860
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..2039
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2123
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            2124..2210
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     exon            2211..5533
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3295..3300
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: AATAAA"
     polyA_site      3314
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="major polyA site"
     regulatory      3540..3545
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: ATTAAA"
     polyA_site      3571
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="major polyA site"
     regulatory      4122..4127
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: AATAAA"
     regulatory      4138..4143
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: AATATA"
     regulatory      4143..4148
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: AACAAA"
     polyA_site      4149
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
     polyA_site      4157
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="major polyA site"
     polyA_site      4161
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
     regulatory      5020..5025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: AATAAA"
     polyA_site      5043
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
     regulatory      5513..5518
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
                     /note="hexamer: AATAAA"
     polyA_site      5533
                     /gene="Mynn"
                     /gene_synonym="2810011C24Rik; Mynr; SBBIZ1"
ORIGIN      
        1 tgctttcgaa catctcatct ctgttgccag gtaagggcat tctggtagat gagctttggt
       61 gagccggttc aaacagaatt ctgggggtcc caagagcttt cggatatgca aaagaggaag
      121 gagtgattgg tctcgactta agcatatccc tcccactcgc cccggtcaag aaccagggtg
      181 cacaacacag tcatctccac tggaggggcg ctaatgaaga caggatgaca ggcgaggaaa
      241 agaactacaa ctcccagcat gcagcgcgca gcgcggttcc cggagaggcc ggctctgcac
      301 tcaagcccgg tctccatcca gaatctgggc cgacagctgc gggctgacaa ggtgagcagc
      361 tcgcaccgga tgcgagtgag caaggaggtg tgatccggag acctgggcat gccgggaagt
      421 cagggctctg agacccagct cgccggccct agtagacttt tagcgtccta tctccggtgt
      481 ccccaatgga ccacacaccc ggacgtgacg ctatcgcaga ggaggaaggg agaggcggag
      541 cgtcgcagtg acgtcctccc aagatggcgg tgagagagtg aagaaactgt ttcccttggg
      601 cggctacgga tcaagggtga aatcccattc tgctagcaaa atgcagtatt cacaccactg
      661 tgagcacctt ttagagagac tgaataagca acgggaagcg ggatttcttt gcgactgtac
      721 cgtagtgatt ggagaattcc agtttaaggc gcataggaat gtgcttgcct cctttagtga
      781 gtattttggg gcgatctaca gaagcacttc tgagaacaat gtttttcttg atcagagtca
      841 ggtgaaggct gacggatttc agaaactgtt ggagtttata tatacaggaa ctttaaatct
      901 cgacagttgg aatgttaaag aaatccatca ggctgctgac tatctcaaag tagaagaggt
      961 agtaactaaa tgtaaaataa agatggagga tttcgctttc attgctagtc cctcttctac
     1021 cgaaatatct agtattactg gaaacatcga attgaatcaa caggcctgtc ttcttaccct
     1081 gcgagattat aacaatcggg agaaatcaga agtctccacg gactcagttc aggcaaaccc
     1141 taaaccacgg gcattgacaa agaaatcgtc tcaaagtaaa aagaagaaga aggccttcag
     1201 ttctcagaaa ccagggcaga gcaaagcagt gcagtacccc agtgacgttc tagagagcgc
     1261 gtctgtggaa ttattcctag agacgagcaa gttgtcctca cctgtagtag agcaaatcat
     1321 tcaaggaaat gacagttcag aacttgagtt gacctcggtt gtggaaaata cttttccaac
     1381 ccaagatatt gtgcaaactg ttacagtcaa acggaaacgt cggaaatcac agtcacattg
     1441 tgctctgaaa gaacactcca tgtctaacat agccagtgta aagagtccat atgagctgga
     1501 gaacgccggg gaagagctgg atgcaaggtt ttccaaggcc aagccaatgt gcaacacttg
     1561 cgggaaggtg ttttcggaag ccagcagcct gcgaaggcac atgagaatac acaaaggagt
     1621 caagccctac gtctgccact tgtgtggaaa ggcatttacc cagtgcaacc aactaaagac
     1681 gcatgtgagg actcacacag gggaaaggcc atataaatgt gaactgtgtg ataaaggatt
     1741 tgctcagaaa tgccagctgg tcttccatag tcgcatgcat catggtgagg aaaaacccta
     1801 taaatgtgat gtgtgcaatt tacagtttgc aacttctagc aacctcaaga ttcatgcaag
     1861 gaaacacagt ggagaaaagc catatgtttg tgatagatgt gggcagagat ttgcccaggc
     1921 cagcacgctg acctatcatg tccgcagaca cactggagaa aagccttatg tgtgcgacac
     1981 ctgcggaaag gcatttgctg tctctagctc tcttatcact cattctcgga aacacacagg
     2041 tgaaaaacca tacatatgtg gtatttgtgg gaaaagtttt atttcctcag gagagctcaa
     2101 caaacacttt cgatcccata caggagaacg accatttatc tgtgaattat gtggaaactc
     2161 atacacagac attaaaaact taaagaagca taaaacaaag gtccattctg gtactgataa
     2221 aaatccagat tgcagtgtag atgaccatgc tgtaagcgaa caagactccg tacagagaag
     2281 tcccttgtca gaaacactag atgtgaagcc ttctgatatg actctaccct tagcgcttcc
     2341 acttgggact gaagaccacc agatgctcct gcctgtcacg gacagtcagt ctcctgcatc
     2401 agacacgctg ctgaggtcca cggtgaatgg gtactcggaa ccgcagttga tttttttaca
     2461 acagttgtac tgactttgag ggcatggact tgctaggccg tcctcggcag agacataact
     2521 atgtctggta aggtgcagag tcgtgttaac taacccccac tcatttgagc cgtgagccca
     2581 ttagtctttg ttcacggaag tgaaagcacc tgaccctgca tcaggcagtg ctggcttggg
     2641 tttttggctt ttattgtaaa cagccagcct gtgaaggagc gcttcccccg caccgcaccg
     2701 cactgttgtg ggtgggtcgg ttttagacac tgttaatgct gccttaattc catcttcact
     2761 ttgcattgta gacttgtttg ttccttaggt cgaatctgac ctggggtttt ttgttgttct
     2821 ctccttgctg tttaaacaaa atctacagta atatcaactt cgaagtgttt ctgtttgtaa
     2881 gccctgtgga ccagtatgga aactgtcgga gggattcaag ttcatgttta tgtctatgaa
     2941 aatttagata ctgaggaaga attgtgctat ttattaatat attcctttag aggtaacttt
     3001 tctaatgaag ccaaacaaag tatttctctt aaaacccaga aaacgtgtgt aaatttgtgt
     3061 tcatttagag tgaattcagt attctggaga aaaccagtgc tcagatccat ttttgtttga
     3121 gttgaaacta tattttttta aatagatatt tggtgttttt aagtggtcag aagacagttt
     3181 tggaatttga ttcattttat attttattag atttgtagat tattggaagt gaatatataa
     3241 caagttttga aaatttttga taagcctatc ttgtatcagt tatgcacttt ttaaaataaa
     3301 tgttctaaaa ggaattttct agatataaaa tacatactag aaatcacttg gcttctaaat
     3361 ttgatgtatt acttagaaaa atcaagaaac ctgagttgca tgcctaaggc aacacacata
     3421 cacacaaata aatatcctta atatcctaac ttcaattata agctatactt ttgggttatc
     3481 agtttgttta ccattttata tttgagtttt ctatagacat gtgtttttca aatttataaa
     3541 ttaaaactgc aacgtttggt tgttggctat agctttatag tgtcctttcc gttcccctgg
     3601 gtgtagcgag ttcagcatcg cccgtcctcc agcctgctcc ctcttcccct ctcactgtct
     3661 gcatatcagt tgatttcact ttgcatttta agttcagttt cccagtcagt tccattgctg
     3721 ataagtcctg gtgactgttt ctcatctctg ccatcactta gttaggtctc acgcgtgttc
     3781 aggactgcac cagaacaggc tcgcagtgtt cactgggact attcttccat cataatcctc
     3841 cctctttggt tccaagtcac agaactaaga agacatacta ggaccctcag ttcttgcaaa
     3901 ctgcaggtgt cttcccattt cttaaagcta tagcattttc acggtaaatt atgaccagcg
     3961 agactaactt aactggagag agtatgaaat accacctttg tacaataaac ttattttatt
     4021 atttagctaa gaaatctgtg tgtatgttaa atgaacatac tgagtttgaa taaaatttgt
     4081 aaggtataaa atgttcagct aatctttttc tggttaaaat caataaaaat ttactggaat
     4141 ataacaaaac tgaaaaagaa attaagactc aacccttttt aacaagtttg ccaaagtgga
     4201 ggggctatgt ttaaatcaca gctgcattaa tccaagcata taatgaacag ttttttaaag
     4261 tgctgtagtt aggtgggcac gcacatacct ataatcacag tattctggga agttaaggca
     4321 agaagattaa acaggattcc aaaagctgct gtcatgatgt catgatgtgc tgtgtgcagt
     4381 ctcctagagt gtaatgatag tcttgttggt gtatcagttc acagtccaga ctggcctagg
     4441 actcctgtgt aacctaaagt ggctctgtcc cccacatcct cctcccgcat tccccaggcg
     4501 agcagcacag cccctaacaa cacagcagca ccaagccact caatccccaa cttgctaact
     4561 agcatctgaa agcttctaaa ttgttacttt cagcattatt tcatataagt ggaatctgaa
     4621 gtaggtcaga ttgttttttt ttttaatttg tattacttgc gtatctaaaa ttattttaga
     4681 ttgatactgg tttagtcatt tgctcttgca gagttatttg tgacgaaagc tcagagactg
     4741 aatgttattc ttttaatgct atgctgttac tactcactct aacgtgcgtg cactttatga
     4801 gaatctggga gtcattctaa cacagagaat ccctgcggta agttctttac ctactctgtt
     4861 atgatgcagt gttttagcaa agcttcttaa ttatttaagt gttatagcag gtgttcaaac
     4921 tttctttaaa atgctgaata tcttagaaag tattttctaa ttttgtatta ttattttact
     4981 ttagagcttt tttaaagagg gaattgtaat tatatattaa ataaaatttg ctgttaaata
     5041 gtattcatgt taaattccat aggatcattt cagtggacaa ttttaaaagc ttcttcaaga
     5101 ttgaaggtct gtcagttctt tgaaaaagta gtttatcatt tctctacatt ttaatcttac
     5161 agaaatggca catgtcaaag cagttaaagt aggtaattaa ctctctacac taattttaaa
     5221 aatatcctag gctaattgtt gtactgtctt tacttctgtc agattggagt ttaataagag
     5281 tacccatgcc cactccagtt tgctgtgctg aatcagatgt gctggggcag atatttgata
     5341 gagaagcctc gtagctgatt tcagcatgga ccaaacactg agagctgcct cccaagcact
     5401 gcttggtgct ctgtctttga gaagcacttg aaatgacgtt ctggaatata tatatatata
     5461 ttatcattta cctggagatt tttaatctgt tattgaatta aaaataccac caaataaaaa
     5521 gatgaattct gcaaaaaaaa aaaaaaaaaa
//
