LOCUS       NM_001418930            1127 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus myosin, light polypeptide 9, regulatory (Myl9),
            transcript variant 2, mRNA.
ACCESSION   NM_001418930 XM_006500453
VERSION     NM_001418930.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Arriagada,C., Lin,E., Schonning,M. and Astrof,S.
  TITLE     Mesodermal fibronectin controls cell shape, polarity, and
            mechanotransduction in the second heart field during cardiac
            outflow tract development
  JOURNAL   Dev Cell 60 (1), 62-84 (2025)
   PUBMED   39413783
REFERENCE   2  (bases 1 to 1127)
  AUTHORS   Guijarro,C., Song,S., Aigouy,B., Clement,R., Villoutreix,P. and
            Kelly,R.G.
  TITLE     Single-cell morphometrics reveals T-box gene-dependent patterns of
            epithelial tension in the Second Heart field
  JOURNAL   Nat Commun 15 (1), 9512 (2024)
   PUBMED   39496595
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1127)
  AUTHORS   Li,Q., Jiang,S., Lei,K., Han,H., Chen,Y., Lin,W., Xiong,Q., Qi,X.,
            Gan,X., Sheng,R., Wang,Y., Zhang,Y., Ma,J., Li,T., Lin,S., Zhou,C.,
            Chen,D. and Yuan,Q.
  TITLE     Metabolic rewiring during bone development underlies tRNA
            m7G-associated primordial dwarfism
  JOURNAL   J Clin Invest 134 (20), e177220 (2024)
   PUBMED   39255038
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1127)
  AUTHORS   Sakai,D., Murakami,Y., Shigeta,D., Tomosugi,M., Sakata-Haga,H.,
            Hatta,T. and Shoji,H.
  TITLE     Glycolytic activity is required for the onset of neural plate
            folding during neural tube closure in mouse embryos
  JOURNAL   Front Cell Dev Biol 11, 1212375 (2023)
   PUBMED   37465012
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1127)
  AUTHORS   Skory,R.M., Moverley,A.A., Ardestani,G., Alvarez,Y.,
            Domingo-Muelas,A., Pomp,O., Hernandez,B., Tetlak,P., Bissiere,S.,
            Stern,C.D., Sakkas,D. and Plachta,N.
  TITLE     The nuclear lamina couples mechanical forces to cell fate in the
            preimplantation embryo via actin organization
  JOURNAL   Nat Commun 14 (1), 3101 (2023)
   PUBMED   37248263
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1127)
  AUTHORS   Vannier,B., Peyton,M., Boulay,G., Brown,D., Qin,N., Jiang,M.,
            Zhu,X. and Birnbaumer,L.
  TITLE     Mouse trp2, the homologue of the human trpc2 pseudogene, encodes
            mTrp2, a store depletion-activated capacitative Ca2+ entry channel
  JOURNAL   Proc Natl Acad Sci U S A 96 (5), 2060-2064 (1999)
   PUBMED   10051594
REFERENCE   7  (bases 1 to 1127)
  AUTHORS   Srivastava,D., Thomas,T., Lin,Q., Kirby,M.L., Brown,D. and
            Olson,E.N.
  TITLE     Regulation of cardiac mesodermal and neural crest development by
            the bHLH transcription factor, dHAND
  JOURNAL   Nat Genet 16 (2), 154-160 (1997)
   PUBMED   9171826
  REMARK    Erratum:[Nat Genet 1997 Aug;16(4):410]
REFERENCE   8  (bases 1 to 1127)
  AUTHORS   Molkentin,J.D., Lin,Q., Duncan,S.A. and Olson,E.N.
  TITLE     Requirement of the transcription factor GATA4 for heart tube
            formation and ventral morphogenesis
  JOURNAL   Genes Dev 11 (8), 1061-1072 (1997)
   PUBMED   9136933
REFERENCE   9  (bases 1 to 1127)
  AUTHORS   Kuo,C.T., Morrisey,E.E., Anandappa,R., Sigrist,K., Lu,M.M.,
            Parmacek,M.S., Soudais,C. and Leiden,J.M.
  TITLE     GATA4 transcription factor is required for ventral morphogenesis
            and heart tube formation
  JOURNAL   Genes Dev 11 (8), 1048-1060 (1997)
   PUBMED   9136932
REFERENCE   10 (bases 1 to 1127)
  AUTHORS   Kubalak,S.W., Miller-Hance,W.C., O'Brien,T.X., Dyson,E. and
            Chien,K.R.
  TITLE     Chamber specification of atrial myosin light chain-2 expression
            precedes septation during murine cardiogenesis
  JOURNAL   J Biol Chem 269 (24), 16961-16970 (1994)
   PUBMED   8207020
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX571766.3 and AL935150.10.
            
            On Mar 24, 2023 this sequence version replaced XM_006500453.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.900989.1,
                                           SRR5189679.12961.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                BX571766.3         35694-35779
            87-296              AL935150.10        4355-4564
            297-458             AL935150.10        6318-6479
            459-1127            AL935150.10        6826-7494
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.77 cM"
     gene            1..1127
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /note="myosin, light polypeptide 9, regulatory"
                     /db_xref="GeneID:98932"
                     /db_xref="MGI:MGI:2138915"
     exon            1..86
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /inference="alignment:Splign:2.1.0"
     exon            87..296
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..631
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /note="isoform a is encoded by transcript variant 2;
                     myosin regulatory light polypeptide 9; myosin regulatory
                     light chain 9; myosin light chain, regulatory C"
                     /codon_start=1
                     /product="myosin regulatory light polypeptide 9 isoform a"
                     /protein_id="NP_001405859.1"
                     /db_xref="GeneID:98932"
                     /db_xref="MGI:MGI:2138915"
                     /translation="MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQN
                     RDGFIDKEDLHDMLASLGKNPTDEYLEGMMNEAPGPINFTMFLTMFGEKLNGTDPEDV
                     IRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFT
                     RILKHGAKDKDD"
     exon            297..458
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /inference="alignment:Splign:2.1.0"
     exon            459..1127
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1109..1114
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /note="hexamer: AATACA"
     polyA_site      1127
                     /gene="Myl9"
                     /gene_synonym="MLC20; Mylc2c; RLC-C"
                     /note="major polyA site"
ORIGIN      
        1 agccaactct cgaagcaccg caacagcgcc gaggactttt cttctctgca gcaggtggga
       61 gcccactcag cacccgggca gctacaggaa acccccaaca cccaaaggca agatgtcgag
      121 caagagagcc aaggccaaga ccaccaagaa gaggccccag agggctacgt ccaatgtctt
      181 cgccatgttt gaccagtccc agatccagga gtttaaggag gccttcaaca tgattgatca
      241 gaaccgagat ggcttcattg ataaggagga cctgcacgac atgctggcct ctctggggaa
      301 gaaccccaca gacgagtatc tggagggcat gatgaacgag gcgccagggc ccatcaactt
      361 caccatgttc ctcacaatgt ttggggagaa gctgaacggc acagaccccg aggatgtgat
      421 ccgcaatgcc tttgcctgct ttgatgagga ggcctcaggc ttcatccacg aggaccacct
      481 gagggagctg ctcaccacca tgggcgaccg attcacggat gaggaggtgg acgagatgta
      541 ccgcgaggca cccattgata agaagggcaa cttcaactac gtggagttca ctcgcatcct
      601 caaacacggc gccaaggaca aggacgacta agctgttctt agctgcccca gtgcctagac
      661 cccatcccag tcacctacct ccccaacaca tacactctac cctccccgtg acgaattagg
      721 gtcccagctc ccagggccgg aactgaaccg taagacccac agggtgaggc aggtgctcta
      781 caatgggccc aggcactaac tagaagggat ctctgaccct acaaggaggg accacagtgg
      841 ggaggtgagc cgagggtggg gccagcaagc accaaggtaa agccactgaa gatagcactc
      901 agccatgccc tcccattccc gggctggcct gaggaaggaa gcacccgtgt tctggtgtcg
      961 gacactaatt cccagcatcc ccacaaaggt acacacccat tcaccatgtc ccttcagagg
     1021 atgacagtct gctcttaggc ttgtggagtt gtctcagcac ccccagaatg cattgaggga
     1081 agggaagctg cctgagggac agtctcttaa tacaaggctg aacacca
//
