LOCUS       NM_172259               1053 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus myosin, light polypeptide 6B (Myl6b), mRNA.
ACCESSION   NM_172259 XM_910012 XM_921505
VERSION     NM_172259.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Chao,C.M., Moiseenko,A., Kosanovic,D., Rivetti,S., El Agha,E.,
            Wilhelm,J., Kampschulte,M., Yahya,F., Ehrhardt,H., Zimmer,K.P.,
            Barreto,G., Rizvanov,A.A., Schermuly,R.T., Reiss,I., Morty,R.E.,
            Rottier,R.J., Bellusci,S. and Zhang,J.S.
  TITLE     Impact of Fgf10 deficiency on pulmonary vasculature formation in a
            mouse model of bronchopulmonary dysplasia
  JOURNAL   Hum Mol Genet 28 (9), 1429-1444 (2019)
   PUBMED   30566624
REFERENCE   2  (bases 1 to 1053)
  AUTHORS   Martin-Alonso,M., Garcia-Redondo,A.B., Guo,D., Camafeita,E.,
            Martinez,F., Alfranca,A., Mendez-Barbero,N., Pollan,A.,
            Sanchez-Camacho,C., Denhardt,D.T., Seiki,M., Vazquez,J.,
            Salaices,M., Redondo,J.M., Milewicz,D. and Arroyo,A.G.
  TITLE     Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to
            aortic aneurysm in mice
  JOURNAL   Circ Res 117 (2), e13-e26 (2015)
   PUBMED   25963716
REFERENCE   3  (bases 1 to 1053)
  AUTHORS   Vincent,S.D., Mayeuf,A., Niro,C., Saitou,M. and Buckingham,M.
  TITLE     Non conservation of function for the evolutionarily conserved prdm1
            protein in the control of the slow twitch myogenic program in the
            mouse embryo
  JOURNAL   Mol Biol Evol 29 (10), 3181-3191 (2012)
   PUBMED   22522309
REFERENCE   4  (bases 1 to 1053)
  AUTHORS   Niro,C., Demignon,J., Vincent,S., Liu,Y., Giordani,J., Sgarioto,N.,
            Favier,M., Guillet-Deniau,I., Blais,A. and Maire,P.
  TITLE     Six1 and Six4 gene expression is necessary to activate the
            fast-type muscle gene program in the mouse primary myotome
  JOURNAL   Dev Biol 338 (2), 168-182 (2010)
   PUBMED   19962975
REFERENCE   5  (bases 1 to 1053)
  AUTHORS   Hailstones,D.L. and Gunning,P.W.
  TITLE     Characterization of human myosin light chains 1sa and 3nm:
            implications for isoform evolution and function
  JOURNAL   Mol Cell Biol 10 (3), 1095-1104 (1990)
   PUBMED   2304459
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC037527.1.
            
            On or before Dec 7, 2005 this sequence version replaced
            XM_921505.1, XM_910012.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC037527.1, SRR7652917.1107935.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 76.77 cM"
     gene            1..1053
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /note="myosin, light polypeptide 6B"
                     /db_xref="GeneID:216459"
                     /db_xref="MGI:MGI:1917789"
     exon            1..58
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
     exon            59..275
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..728
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /note="smooth muscle and nonmuscle myosin light chain
                     alkali 6B; myosin light chain 1 slow a"
                     /codon_start=1
                     /product="myosin light chain 6B"
                     /protein_id="NP_758463.1"
                     /db_xref="CCDS:CCDS24279.1"
                     /db_xref="GeneID:216459"
                     /db_xref="MGI:MGI:1917789"
                     /translation="MPPKKDAPVKKPAGPSISKPAAKSTPGTPLAKAKAEPAAPQAPA
                     KSQEPPVDLSKVVIEFNKDQLEEFREAFELFDRVGDGKILYSQCGDLMRALGQNPTNA
                     EVLKVLGNPKNEELKSRRVDFETFLPMLQAVAKNRDQGTYEDYLEGLRVFDKEGNGKV
                     MGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHILSL"
     exon            276..303
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
     exon            304..447
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
     exon            448..621
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
     exon            622..699
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
     exon            700..1026
                     /gene="Myl6b"
                     /gene_synonym="5730437E04Rik; MLC1SA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggacaggag ctgccctgag tcccgccccc cacctgcccc ttcctcggac ccggcaagag
       61 atgggtgccc ccatcagcac attgttcttt ggccacctga catcatgcct cccaagaagg
      121 atgctcccgt gaagaaacca gcagggccct ccatctctaa gcctgctgcc aagtctacac
      181 cagggacccc tctagccaag gccaaggctg agccggctgc cccccaggca cctgcaaaat
      241 cccaggagcc ccctgttgat ctctccaaag tggtgatcga gtttaacaag gaccagctgg
      301 aggaattcag agaggccttt gagctgtttg accgagtagg tgatggcaag atcctgtaca
      361 gccagtgtgg ggacctgatg agggccctgg gccagaaccc taccaacgcc gaggtgctca
      421 aggtcctggg gaaccccaaa aacgaggagc tgaagtcccg acgtgtagac tttgagacgt
      481 tcctgcccat gctgcaggca gtggccaaga accgggacca aggcacatat gaggactacc
      541 tagaggggct tcgtgtgttt gacaaagagg gcaacggcaa ggtcatgggt gcagagctca
      601 gacatgttct taccactctc ggagagaaga tgactgagga agaggtagag actgttctgg
      661 caggccacga ggacagcaac ggctgcatca actatgaggc cttcctgaag catatcctaa
      721 gcctctgagc tccgcaggtg gccctccagc cagcccctgg tatccgcttg agaggcaagg
      781 gtcctcgatc caccagatag aagcgcaggc agtgcgtctc cgcgcccgtc cgtagcgcag
      841 ccgccagggc tggactattt ccttccccac cccccacccc ctcccacccc caccccaccc
      901 cagccccgac tcccacccca cgtagaacct gcagcgacgg aaacttgccc cacctcctgt
      961 gcggccagaa gcgcgttcct gccactaggg ggcacttaca gttttgaaat aaaaacatgg
     1021 ttcctgaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
