LOCUS       NM_001355755             916 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant
            2, mRNA.
ACCESSION   NM_001355755 XM_006532417
VERSION     NM_001355755.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 916)
  AUTHORS   Van Wauwe,J., Mahy,A., Craps,S., Ekhteraei-Tousi,S., Vrancaert,P.,
            Kemps,H., Dheedene,W., Donate Puertas,R., Trenson,S.,
            Roderick,H.L., Beerens,M. and Luttun,A.
  TITLE     PRDM16 determines specification of ventricular cardiomyocytes by
            suppressing alternative cell fates
  JOURNAL   Life Sci Alliance 7 (12), e202402719 (2024)
   PUBMED   39304345
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 916)
  AUTHORS   Hashimoto,K., Ohira,M., Kodama,A., Kimoto,M., Inoue,M., Tone,S.,
            Usui,Y., Hanashima,A., Goto,T., Ogura,Y., Ujihara,Y. and Mohri,S.
  TITLE     Loss of connectin novex-3 leads to heart dysfunction associated
            with impaired cardiomyocyte proliferation and abnormal nuclear
            mechanics
  JOURNAL   Sci Rep 14 (1), 13727 (2024)
   PUBMED   38877142
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 916)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 916)
  AUTHORS   Kurz,J., Weiss,A.C., Thiesler,H., Qasrawi,F., Deuper,L., Kaur,J.,
            Rudat,C., Ludtke,T.H., Wojahn,I., Hildebrandt,H., Trowe,M.O. and
            Kispert,A.
  TITLE     Notch signaling is a novel regulator of visceral smooth muscle cell
            differentiation in the murine ureter
  JOURNAL   Development 149 (4) (2022)
   PUBMED   35103284
REFERENCE   5  (bases 1 to 916)
  AUTHORS   Hayashi,S., Manabe,I., Suzuki,Y., Relaix,F. and Oishi,Y.
  TITLE     Klf5 regulates muscle differentiation by directly targeting
            muscle-specific genes in cooperation with MyoD in mice
  JOURNAL   Elife 5, e17462 (2016)
   PUBMED   27743478
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 916)
  AUTHORS   Dyson,P.J., de Smet,C., Knight,A.M., Simon-Chazottes,D.,
            Guenet,J.L. and Boon,T.
  TITLE     Mapping of the genes encoding tum- transplantation antigens P91A,
            P35B, and P198
  JOURNAL   Immunogenetics 35 (5), 316-323 (1992)
   PUBMED   1348494
REFERENCE   7  (bases 1 to 916)
  AUTHORS   Boyer,S., Montagutelli,X., Gomes,D., Simon-Chazottes,D.,
            Guenet,J.L. and Dupouey,P.
  TITLE     Recent evolutionary origin of the expression of the glial
            fibrillary acidic protein (GFAP) in lens epithelial cells. A
            molecular and genetic analysis of various mouse species
  JOURNAL   Brain Res Mol Brain Res 10 (2), 159-166 (1991)
   PUBMED   1712888
REFERENCE   8  (bases 1 to 916)
  AUTHORS   Hearne,C.M., McAleer,M.A., Love,J.M., Aitman,T.J., Cornall,R.J.,
            Ghosh,S., Knight,A.M., Prins,J.B. and Todd,J.A.
  TITLE     Additional microsatellite markers for mouse genome mapping
  JOURNAL   Mamm Genome 1 (4), 273-282 (1991)
   PUBMED   1794058
REFERENCE   9  (bases 1 to 916)
  AUTHORS   Lyons,G.E., Ontell,M., Cox,R., Sassoon,D. and Buckingham,M.
  TITLE     The expression of myosin genes in developing skeletal muscle in the
            mouse embryo
  JOURNAL   J Cell Biol 111 (4), 1465-1476 (1990)
   PUBMED   2211821
REFERENCE   10 (bases 1 to 916)
  AUTHORS   Seharaseyon,J., Bober,E., Hsieh,C.L., Fodor,W.L., Francke,U.,
            Arnold,H.H. and Vanin,E.F.
  TITLE     Human embryonic/atrial myosin alkali light chain gene:
            characterization, sequence, and chromosomal location
  JOURNAL   Genomics 7 (2), 289-293 (1990)
   PUBMED   2129532
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603709.14, BY107860.1, AI893273.1, AA230721.1, AK013098.1 and
            CO041482.1.
            
            On Sep 27, 2017 this sequence version replaced XM_006532417.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1, 2 and 3 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB203222.1, CB588200.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AL603709.14        123179-123238
            61-131              BY107860.1         2-72
            132-577             AI893273.1         1-446
            578-794             AA230721.1         456-672
            795-898             AK013098.1         701-804
            899-916             CO041482.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..916
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 67.79 cM"
     gene            1..916
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /note="myosin, light polypeptide 4"
                     /db_xref="GeneID:17896"
                     /db_xref="MGI:MGI:97267"
     exon            1..294
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     exon            295..322
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     exon            323..472
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     exon            473..646
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     exon            647..724
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     exon            725..769
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     exon            770..900
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /inference="alignment:Splign:2.1.0"
     regulatory      870..875
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /note="hexamer: AATAAA"
     polyA_site      900
                     /gene="Myl4"
                     /gene_synonym="ALC1; AMLC; ELC; ELC1a; GT1; MLC1a;
                     MLC1EMB; Myla"
                     /note="major polyA site"
ORIGIN      
        1 ttttatagtc agcagcagtt gctgctgccc tccccagccc ctctgtgggg gctcctaccc
       61 agaataaaag caggggcagg ccttccagtc tcccatcttc tctctcacga gccacctctc
      121 ctcctttggt tcctttctag gtcccacctc cactggagag cctaaagcaa catgcctccc
      181 aagaaacccg agcctaagaa ggagactgcc aagccggctg cagcccctgc tccagctgca
      241 tccgcagctc cggagcccct caaggactct gcctttgacc caaagagtgt gaagatagac
      301 ttcagtgctg accagatcga agaattcaaa gaggcctttt cattgtttga ccggactcca
      361 acgggagaga tgaagatcac ctacgggcag tgtggggacg tgctgcgggc cctgggccag
      421 aaccccacca acgcagaggt gctgcgcgtt ttgggcaaac ccaagcctga agagatgagt
      481 tccaagacac tggacttcga gatgttcctg cccatcctgc aacacatctc ccgcaacaag
      541 gagcagggca cctatgagga cttcgtggag gggctgcggg tctttgacaa agaaagcaac
      601 ggcacagtca tgggtgcaga gcttcggcat gtccttgcta ccctgggaga gaagatgagc
      661 gaggcagagg tggagcagct gttgtctggg caggaggatg ccaatggctg catcaactat
      721 gaagcctttg tcaagcacat catgtctggg taaagcacgt ttctccaggg tgcttggccc
      781 tgcgtgagaa agcaagagat ccacagcggc tgttactgtt acggagtatt ggactcacat
      841 ggcttctctg acccacaacc ttccctggaa ataaagagcc ccagcttgga gtttcattaa
      901 aaaaaaaaaa aaaaaa
//
