LOCUS       NM_001164171            6079 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus myosin, heavy polypeptide 6, cardiac muscle, alpha
            (Myh6), transcript variant 1, mRNA.
ACCESSION   NM_001164171
VERSION     NM_001164171.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6079)
  AUTHORS   Fan,W., Li,Z., He,X., Wang,X., Sun,M. and Yang,Z.
  TITLE     SLC25A1 regulates placental development to ensure embryonic heart
            morphogenesis
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39591637
REFERENCE   2  (bases 1 to 6079)
  AUTHORS   Lu,M., Li,S., Han,Z., Ma,B., Wang,L., Wan,F., Lei,S., Nie,Y. and
            Wang,J.
  TITLE     Carrying both the heterozygous Myh6-R453C and Tnnt2-R92W mutations
            aggravate the hypertrophic cardiomyopathy phenotype in mice
  JOURNAL   Biochem Biophys Res Commun 733, 150582 (2024)
   PUBMED   39191188
  REMARK    GeneRIF: Carrying both the heterozygous Myh6-R453C and Tnnt2-R92W
            mutations aggravate the hypertrophic cardiomyopathy phenotype in
            mice.
REFERENCE   3  (bases 1 to 6079)
  AUTHORS   Allwood,M.A., Edgett,B.A., Platt,M.J., Marrow,J.P., Coyle-Asbil,B.,
            Holjak,E.J.B., Nelson,V.L., Bangali,S., Alshamali,R., Jacyniak,K.,
            Klein,J.M., Farquharson,L., Romanova,N., Northrup,V., Ogilvie,L.M.,
            Ayoub,A., Ask,K., Vickaryous,M.K., Hare,G.M.T., Brunt,K.R. and
            Simpson,J.A.
  TITLE     Novel roles of cardiac-derived erythropoietin in cardiac
            development and function
  JOURNAL   J Mol Cell Cardiol 188, 90-104 (2024)
   PUBMED   38382296
REFERENCE   4  (bases 1 to 6079)
  AUTHORS   Beutner,G., Burris,J.R., Collins,M.P., Kulkarni,C.A.,
            Nadtochiy,S.M., de Mesy Bentley,K.L., Cohen,E.D., Brookes,P.S. and
            Porter,G.A. Jr.
  TITLE     Coordinated metabolic responses to cyclophilin D deletion in the
            developing heart
  JOURNAL   iScience 27 (3), 109157 (2024)
   PUBMED   38414851
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6079)
  AUTHORS   Sur,M., Rasquinha,M.T., Mone,K., Massilamany,C., Lasrado,N.,
            Gurumurthy,C., Sobel,R.A. and Reddy,J.
  TITLE     Investigation into Cardiac Myhc-alpha 334-352-Specific TCR
            Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the
            Development of Cardiac Autoimmunity
  JOURNAL   Cells 13 (3), 234 (2024)
   PUBMED   38334626
  REMARK    GeneRIF: Investigation into Cardiac Myhc-alpha 334-352-Specific TCR
            Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the
            Development of Cardiac Autoimmunity.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6079)
  AUTHORS   Houzelstein,D., Lyons,G.E., Chamberlain,J. and Buckingham,M.E.
  TITLE     Localization of dystrophin gene transcripts during mouse
            embryogenesis
  JOURNAL   J Cell Biol 119 (4), 811-821 (1992)
   PUBMED   1429837
REFERENCE   7  (bases 1 to 6079)
  AUTHORS   Quinn-Laquer,B.K., Kennedy,J.E., Wei,S.J. and Beisel,K.W.
  TITLE     Characterization of the allelic differences in the mouse cardiac
            alpha-myosin heavy chain coding sequence
  JOURNAL   Genomics 13 (1), 176-188 (1992)
   PUBMED   1577481
REFERENCE   8  (bases 1 to 6079)
  AUTHORS   Haefliger,J.A., Bruzzone,R., Jenkins,N.A., Gilbert,D.J.,
            Copeland,N.G. and Paul,D.L.
  TITLE     Four novel members of the connexin family of gap junction proteins.
            Molecular cloning, expression, and chromosome mapping
  JOURNAL   J Biol Chem 267 (3), 2057-2064 (1992)
   PUBMED   1370487
REFERENCE   9  (bases 1 to 6079)
  AUTHORS   Subramaniam,A., Jones,W.K., Gulick,J., Wert,S., Neumann,J. and
            Robbins,J.
  TITLE     Tissue-specific regulation of the alpha-myosin heavy chain gene
            promoter in transgenic mice
  JOURNAL   J Biol Chem 266 (36), 24613-24620 (1991)
   PUBMED   1722208
REFERENCE   10 (bases 1 to 6079)
  AUTHORS   Robbins,J., Gulick,J., Sanchez,A., Howles,P. and Doetschman,T.
  TITLE     Mouse embryonic stem cells express the cardiac myosin heavy chain
            genes during development in vitro
  JOURNAL   J Biol Chem 265 (20), 11905-11909 (1990)
   PUBMED   1694848
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025533.11.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC110700.1, SRR10223970.17007.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                CT025533.11        52070-52123
            55-187              CT025533.11        52778-52910
            188-403             CT025533.11        53202-53417
            404-547             CT025533.11        54638-54781
            548-704             CT025533.11        55019-55175
            705-732             CT025533.11        55270-55297
            733-844             CT025533.11        55545-55656
            845-937             CT025533.11        55899-55991
            938-1001            CT025533.11        56560-56623
            1002-1100           CT025533.11        56850-56948
            1101-1204           CT025533.11        57407-57510
            1205-1343           CT025533.11        57594-57732
            1344-1612           CT025533.11        58139-58407
            1613-1783           CT025533.11        58706-58876
            1784-2093           CT025533.11        59918-60227
            2094-2164           CT025533.11        60847-60917
            2165-2252           CT025533.11        61243-61330
            2253-2370           CT025533.11        61417-61534
            2371-2494           CT025533.11        61675-61798
            2495-2631           CT025533.11        62039-62175
            2632-2887           CT025533.11        64724-64979
            2888-3130           CT025533.11        65146-65388
            3131-3307           CT025533.11        65547-65723
            3308-3453           CT025533.11        65958-66103
            3454-3544           CT025533.11        66341-66431
            3545-3934           CT025533.11        68024-68413
            3935-4061           CT025533.11        68499-68625
            4062-4180           CT025533.11        68714-68832
            4181-4377           CT025533.11        69143-69339
            4378-4561           CT025533.11        69882-70065
            4562-4727           CT025533.11        70220-70385
            4728-4852           CT025533.11        70472-70596
            4853-5161           CT025533.11        71455-71763
            5162-5365           CT025533.11        72161-72364
            5366-5491           CT025533.11        73891-74016
            5492-5767           CT025533.11        74124-74399
            5768-5863           CT025533.11        75434-75529
            5864-5998           CT025533.11        76190-76324
            5999-6079           CT025533.11        76676-76756
FEATURES             Location/Qualifiers
     source          1..6079
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 28.01 cM"
     gene            1..6079
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /note="myosin, heavy polypeptide 6, cardiac muscle, alpha"
                     /db_xref="GeneID:17888"
                     /db_xref="MGI:MGI:97255"
     exon            1..54
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            55..187
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            188..403
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            404..547
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            548..704
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            705..732
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            733..844
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            845..937
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1001
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1100
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1204
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1343
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1612
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1783
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..2093
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..2164
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2252
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2370
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2371..2494
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2631
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2632..2887
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            2888..3130
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            3131..3307
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            3308..3453
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            3454..3544
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            3545..3934
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            3935..4061
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            4062..4180
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            4181..4377
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            4378..4561
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            4562..4727
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            4728..4852
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            4853..5161
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            5162..5365
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            5366..5491
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            5492..5767
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            5768..5863
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            5864..5998
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     exon            5999..6079
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6054..6059
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /note="hexamer: AATAAA"
     polyA_site      6077
                     /gene="Myh6"
                     /gene_synonym="A830009F23Rik; alpha-MHC; alphaMHC; Myhc-a;
                     Myhca"
                     /note="major polyA site"
ORIGIN      
        1 atataaaggg gctggagcac tgagagctgt cagacagaga tttctccaac ccaggatctc
       61 tggattggtc tcccagcctc tgctactcct cttcctgcct gttcctctct ccgtccagct
      121 gcgccactgt ggtgcctcgt tccagctgtg gtccacattc ttcaggattc tctgaaaagt
      181 taaccagagt ttgagtgaca gaatgacgga cgcccagatg gctgacttcg gggcagcagc
      241 ccagtacctc cgaaagtcag agaaggaacg cctagaggcc cagacccggc cctttgacat
      301 ccgcacggag tgcttcgtgc ctgatgacaa ggaggagtat gttaaggcca aggtcgtgtc
      361 ccgggaaggg ggcaaagtca ctgcggaaac tgaaaacgga aagacggtga ccataaagga
      421 ggaccaggtg atgcagcaga acccacccaa gttcgacaag atcgaggaca tggccatgct
      481 gaccttcctg cacgagccgg ctgtgctgta caacctcaag gagcgctacg cggcctggat
      541 gatctatacc tactcaggcc tcttctgcgt caccgtcaac ccctataagt ggctgcctgt
      601 gtacaatgcg gaagtggtgg ccgcctaccg gggcaagaag aggagcgagg cccctcctca
      661 catcttctcc atctctgaca acgcctatca gtacatgctg acagatcggg agaatcagtc
      721 catcctcatc accggagaat ccggagcggg gaagactgtg aacacaaaac gtgtcatcca
      781 gtactttgcc agcattgcag ccatagggga ccgtagcaag aaggaaaatc ctaatgcaaa
      841 caagggcacc ctggaggacc agattatcca ggctaacccc gctctggagg ccttcggcaa
      901 cgccaagact gtccggaatg acaactcctc ccgctttggg aaattcatca ggatccactt
      961 tggagctact ggaaagctgg cttctgcaga catagagacc taccttctgg agaagtcccg
     1021 ggtgatcttc cagctaaagg ctgagaggaa ctaccacatc ttctaccaga tcctgtccaa
     1081 caagaagccg gagctgctgg acatgctgct ggtcaccaac aacccatacg actacgcctt
     1141 cgtctctcag ggagaggtgt ccgtggcctc cattgatgac tctgaggagc tcttggccac
     1201 tgatagtgcc tttgatgtgc tgagcttcac ggcagaggag aaggctggtg tctacaagct
     1261 gacaggggcc atcatgcact acggaaacat gaagttcaag cagaagcagc gggaggagca
     1321 ggcggagcct gatggcacag aagatgctga caaatctgcc taccttatgg ggctgaactc
     1381 agctgacctg ctcaagggcc tgtgtcaccc tcgggtgaag gtggggaacg agtatgtcac
     1441 caaggggcag agtgtacagc aagtgtacta ttccatcggg gcactggcca agtcagtgta
     1501 cgagaagatg ttcaactgga tggtgacacg catcaacgca accctggaga ccaagcagcc
     1561 gcgccagtac ttcataggtg tcctggacat tgccggcttt gagatcttcg atttcaacag
     1621 ctttgagcag ctgtgcatca acttcaccaa tgagaagctg cagcagttct tcaaccacca
     1681 catgttcgtg ctggagcagg aggagtacaa gaaggagggc attgagtggg agtttatcga
     1741 cttcggcatg gacctgcagg cctgcatcga cctcatcgag aagcccatgg gcatcatgtc
     1801 catcctcgag gaggagtgca tgttccccaa ggcctcagac atgaccttca aggccaagct
     1861 gtatgacaac cacctgggca aatccaacaa cttccagaag cctcgcaatg tcaaggggaa
     1921 gcaggaagcc cacttctcct tggtccacta tgctggcacc gtggactaca acattatggg
     1981 ctggctggaa aagaacaagg acccactcaa tgagacggtg gtgggtttgt accagaagtc
     2041 ctccctcaag ctcatggcta cactcttctc tacctatgct tctgctgata ccggtgacag
     2101 tggtaaaggc aaaggaggca agaagaaagg ctcatccttc caaacagtgt ctgctctcca
     2161 ccgggaaaat ctgaacaagc tgatgacaaa cctgaagacc acccaccctc actttgtgcg
     2221 ctgcatcatt cccaacgagc gaaaggctcc aggggtgatg gacaaccccc tggtcatgca
     2281 ccagctgcga tgcaatggcg tgctggaggg tatccgcatc tgcaggaagg gcttccccaa
     2341 ccgcattctc tatggggact tccggcagag gtatcgcatc ctgaacccag cagccatccc
     2401 tgaggggcaa ttcattgata gcaggaaagg ggctgagaaa ctgctgggct ccctggacat
     2461 tgaccacaac caatacaagt ttggccacac caaggtgttc ttcaaggcgg gcctgctggg
     2521 gctgctcgag gagatgcgag atgagaggct gagccgtatc atcaccagaa tccaggccca
     2581 ggcccgaggg cagctcatgc gcattgagtt caagaagata gtggaacgca gggatgccct
     2641 gctggttatc cagtggaaca ttcgggcctt catgggggtc aagaattggc catggatgaa
     2701 gctctacttc aagatcaaac cgctgctgaa gagcgcagag acggagaagg agatggccaa
     2761 catgaaggag gagtttgggc gagtcaaaga tgcactggag aagtctgagg ctcgccgcaa
     2821 ggagctggag gagaagatgg tgtccctgct gcaggagaag aatgacctac agctccaagt
     2881 gcaggcggaa caagacaacc tcaatgatgc agaggagcgc tgtgaccagc tgatcaagaa
     2941 caagatccag ctggaggcca aggtgaagga gatgaccgag aggctggagg acgaggagga
     3001 gatgaacgcc gagctcactg ccaagaagcg caagctggaa gatgagtgct cagagctcaa
     3061 gaaggatatt gatgacctgg agctgacgct ggccaaggtg gaaaaggaaa agcatgcaac
     3121 agagaacaag gttaaaaacc taacagagga gatggctggg ctggatgaaa tcattgccaa
     3181 gctgaccaaa gagaagaaag ctctgcaaga agcccaccag caagccctcg atgacctgca
     3241 ggctgaagaa gacaaggtca acacgctgac caagtccaaa gtcaagctgg agcagcaggt
     3301 ggatgatctg gagggatccc tggagcagga gaagaaagtg cgcatggacc tagagcgagc
     3361 caagcggaag ctggagggag acctgaagct gacccaggag agcatcatgg acctggagaa
     3421 tgacaagctt cagctggaag aaaagctcaa gaagaaagag ttcgacatca gtcagcagaa
     3481 cagtaaaatt gaggacgagc aggccctggc tcttcagctg cagaagaaac tgaaggaaaa
     3541 ccaggcacgc atcgaggagc tggaggagga gctggaggca gagcgcacag cccgggctaa
     3601 ggtggagaag ctgcgctctg acctgtcccg ggagctggag gagatcagtg agaggctgga
     3661 ggaggcaggc ggggccacat ccgtgcagat agagatgaat aagaagcgcg aggccgagtt
     3721 ccagaagatg cggcgggacc tggaggaggc cacgctgcag cacgaggcca cggcggcggc
     3781 cctgcgcaag aagcatgctg acagcgtggc ggagctgggc gagcagatcg acaacctcca
     3841 gcgggtgaag cagaagctgg agaaagagaa gagcgagttc aagctggagc tggatgacgt
     3901 cacctccaac atggagcaga tcatcaaggc caaggccaac ctggagaaag tgtcccggac
     3961 actggaggac caggccaatg agtaccgcgt gaagctggaa gaagcccagc gctccctcaa
     4021 tgacttcacc acacagcgag ccaagctgca gacagagaac ggggagttgg ctaggcaact
     4081 ggaagaaaag gaggcattga tttcccagct gacccgaggc aagctctcct acacccagca
     4141 gatggaggac ctcaagaggc aactggagga ggaaggcaag gccaagaacg ccctggccca
     4201 cgcactgcaa tcatcccggc atgactgtga cctgctgagg gaacagtatg aagaagaaat
     4261 ggaggccaag gctgagctac agcgtgtcct gtccaaggcc aactcagagg tggcccagtg
     4321 gaggaccaag tatgagacgg atgccataca gaggacggag gagctggagg aagccaagaa
     4381 gaagctggct cagaggctgc aggatgcaga ggaggcagtg gaggccgtca acgccaagtg
     4441 ttcctccctg gagaagacca agcacaggct gcagaatgag atcgaggacc tgatggtgga
     4501 cgtggagcgc tccaatgccg ccgccgcagc cctggacaag aagcagagga actttgacaa
     4561 gatcctggct gagtggaagc agaagtatga ggagtcgcag tcagagctgg agtcttccca
     4621 gaaggaggcg cgctccctga gcacagagct cttcaagctc aagaacgcct atgaggagtc
     4681 tctggagcac ctggagacct tcaagcggga gaacaagaac ctccaggagg agatctcaga
     4741 cctgactgaa cagctgggag aaggggggaa aaacgtgcac gagctggaga agatccgcaa
     4801 acagctggag gtggagaagc tggagctgca gtcagccctg gaggaggctg aggcctccct
     4861 ggagcacgag gagggcaaga tcctccgtgc ccagctggag ttcaaccaga tcaaggcaga
     4921 gatcgaaagg aagctggcag agaaggatga ggagatggag caggccaagc gcaaccacct
     4981 gcggatggtg gactccctgc agacctccct ggatgcggag acacgcagcc gcaatgaggc
     5041 cctgcgggtg aagaagaaga tggagggcga cctcaacgag atggagatcc agctcagcca
     5101 ggccaataga atagcctcag aggcacagaa acacctgaag aattctcaag ctcacttgaa
     5161 ggacacccag ctccagctgg atgatgctgt ccatgccaat gacgacctga aggagaacat
     5221 cgccatcgtg gaacggcgca acaacctgct gcaggcggag ctggaggagc tgcgggctgt
     5281 ggtggagcag acggagcggt ctcggaagct ggcagagcag gagctgattg agaccagcga
     5341 gcgggtgcag ctgctgcact cgcagaacac cagcctcatc aaccagaaga agaagatgga
     5401 gtcagacctg acccaactcc agacagaagt agaggaggca gtgcaggagt gtaggaacgc
     5461 agaggagaag gccaagaagg ccatcacaga tgccgcaatg atggctgagg agctgaagaa
     5521 ggagcaggac accagcgccc acctggagcg catgaagaag aacatggagc agaccatcaa
     5581 ggacttgcag caccgtctgg acgaggcaga gcagatcgcc ctcaagggcg gcaagaagca
     5641 gctgcagaag ctggaggccc gggtccggga gctggagaat gagctggagg ctgagcagaa
     5701 gcgcaatgca gagtcggtga agggcatgag gaagagcgag cggcgcatca aggagctcac
     5761 ctaccagaca gaggaagaca agaagaactt aatgcggctg caggacctgg tggacaagct
     5821 acagttgaag gtgaaggcct acaagcgcca ggctgaggag gcggaggagc aggccaacac
     5881 caacctgtcc aagttccgca aggtgcagca cgagctggat gaggcggagg agagggcgga
     5941 catcgccgag tcccaggtca acaagctgcg ggccaagagc cgggacattg gtgccaagaa
     6001 gatgcacgac gaggaataac ctctccagca gaccctcgct gtggccaatc cacaataaac
     6061 ataaacgttc gactctgcc
//
