LOCUS       NM_001166210            6883 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus myosin, heavy chain 15 (Myh15), mRNA.
ACCESSION   NM_001166210 XM_001002743 XM_992311
VERSION     NM_001166210.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6883)
  AUTHORS   Rossi AC, Mammucari C, Argentini C, Reggiani C and Schiaffino S.
  TITLE     Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b
            and MYH15 are expressed in extraocular muscles and muscle spindles
  JOURNAL   J Physiol 588 (Pt 2), 353-364 (2010)
   PUBMED   19948655
  REMARK    GeneRIF: MYH15, the ortholog of ventricular MYH of frogs and birds,
            is selectively expressed in the orbital layer of mammalian
            extraocular muscles and in the extracapsular region of bag fibers
            of muscle spindles.
REFERENCE   2  (bases 1 to 6883)
  AUTHORS   Sambasivan R, Gayraud-Morel B, Dumas G, Cimper C, Paisant S, Kelly
            RG and Tajbakhsh S.
  TITLE     Distinct regulatory cascades govern extraocular and pharyngeal arch
            muscle progenitor cell fates
  JOURNAL   Dev Cell 16 (6), 810-821 (2009)
   PUBMED   19531352
  REMARK    Erratum:[Dev Cell. 2009 Jul;17(1):150. Kelly, Robert [corrected to
            Kelly, Robert G]]
REFERENCE   3  (bases 1 to 6883)
  AUTHORS   Pritsker M, Doniger TT, Kramer LC, Westcot SE and Lemischka IR.
  TITLE     Diversification of stem cell molecular repertoire by alternative
            splicing
  JOURNAL   Proc Natl Acad Sci U S A 102 (40), 14290-14295 (2005)
   PUBMED   16183747
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154447.2, AC122233.4 and AC116470.12.
            
            On Feb 16, 2019 this sequence version replaced NM_001166210.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-171               AC154447.2         16058-16228         c
            172-278             AC154447.2         12040-12146         c
            279-422             AC154447.2         8529-8672           c
            423-579             AC154447.2         4088-4244           c
            580-607             AC154447.2         3438-3465           c
            608-701             AC154447.2         2495-2588           c
            702-794             AC122233.4         118531-118623       c
            795-858             AC122233.4         116018-116081       c
            859-954             AC122233.4         115839-115934       c
            955-1058            AC122233.4         106074-106177       c
            1059-1197           AC122233.4         104460-104598       c
            1198-1316           AC122233.4         100704-100822       c
            1317-1466           AC122233.4         97023-97172         c
            1467-1637           AC122233.4         95609-95779         c
            1638-1814           AC122233.4         87812-87988         c
            1815-1947           AC122233.4         86727-86859         c
            1948-2015           AC122233.4         84120-84187         c
            2016-2103           AC122233.4         83164-83251         c
            2104-2221           AC122233.4         80924-81041         c
            2222-2345           AC122233.4         79956-80079         c
            2346-2482           AC122233.4         77168-77304         c
            2483-2738           AC122233.4         65032-65287         c
            2739-2981           AC122233.4         59536-59778         c
            2982-3158           AC122233.4         58414-58590         c
            3159-3304           AC122233.4         55725-55870         c
            3305-3395           AC122233.4         54246-54336         c
            3396-3785           AC122233.4         51820-52209         c
            3786-3912           AC122233.4         44058-44184         c
            3913-4031           AC122233.4         43679-43797         c
            4032-4228           AC122233.4         41540-41736         c
            4229-4578           AC122233.4         37244-37593         c
            4579-4703           AC122233.4         34112-34236         c
            4704-4819           AC122233.4         31351-31466         c
            4820-5012           AC122233.4         25162-25354         c
            5013-5216           AC122233.4         24119-24322         c
            5217-5342           AC122233.4         20176-20301         c
            5343-5513           AC122233.4         14246-14416         c
            5514-5618           AC122233.4         10153-10257         c
            5619-5714           AC122233.4         1662-1757           c
            5715-5849           AC122233.4         362-496             c
            5850-6883           AC116470.12        46923-47956
FEATURES             Location/Qualifiers
     source          1..6883
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 30.75 cM"
     gene            1..6883
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /note="myosin, heavy chain 15"
                     /db_xref="GeneID:667772"
                     /db_xref="MGI:MGI:3643515"
     exon            1..171
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..5864
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /codon_start=1
                     /product="myosin-15"
                     /protein_id="NP_001159682.1"
                     /db_xref="CCDS:CCDS49868.1"
                     /db_xref="GeneID:667772"
                     /db_xref="MGI:MGI:3643515"
                     /translation="MDLSEFGDATAFLRRNKADPLFQPPAFDGKKKCWVPDGKNAYIE
                     AEVKESGDDGQVIVETRDGEIMRIKEDKLQQMNPEELEMIEDLSMLLYLNEASVLHTL
                     RRRYDHWMIYTYSGIFCVAINPYKWLPVYQKEVMAAYKRKRRSEVPPHIFAVANRAFQ
                     DMLRNGENQSIVFTGESGSGKTVNTKLIIQYFATMAAISEPKKKLGNLEDQIVKMNPL
                     LEAFGNAKTQKNDNSSRFGKLIRIHFGARGTLSFADIQIYFLEKSRVVYQQPGERNYH
                     IFYQILSGNQELRNMLLVSTNPSDFHICSCGVVAVESLDDAKEFLATEKAIDVLGFLP
                     DEKFGCYKLVGAIMHFGNLKFKRNLREEQLEADGTENADKAAFLMGIHASELLKGLIY
                     PRIKVGNEYVTRSQNLQQVTYAVGALSQSIYERMFQWLVARMNQVLDAKLTSHFFVGI
                     LDTTGFEILDYNSLEQLCINFTNEKLQQFFNQQLFILEQEEYRKEGLDWLSIDYGLDV
                     QACIDFIEKPMGIFSILEEECMLPKATDQMFKTKLFDHHFGKSAYFQTPTSPEKNFEV
                     HFELAHYAGVVPYNISGWIGKNKGLLNETVVALLQKSSNKVLANLFTKDIIAGSASQF
                     GEKTHKKGTSFHLITSLHKENINKLMTDLKSTAPHFVRCINPNKNKIPGVMDPFLVLQ
                     QLRCNGVLEGIRVCCEAFPSWMLYDDFKQRYWILNPRIFSKSKFVSSRKATEEVLDFL
                     EIDHPHYQCGVTKVFFKAFILDQLEERRDEKISKVFTLFQARARGKLMRITFQKILEE
                     RDALALIQENIRAFIAVKNCPWMGLFFKIKPLAKSVGAGEEIAGLKEECAQLQKALES
                     SESQREELKTKQVSLVQEKNDLRLQLQAEQETLANSEEQCESLIKSKVELEVKIKELS
                     RQVEEEEEINSELTARGRKLEDECSELKKEIYDLEAILAKSEKGKCAAEHKVRNLTEE
                     VHSLNEEVSKLSRVVKDAQETQQQTQEQLHIEEEKLSNMSKANLKLAQQIDVLEGDLE
                     RERKARMKCEREKRKLQDELKMNQEGAENLESSRQKLAEQLRKKEFEMGQMNSKVENE
                     KNQVSQLQKMVKELQTHILNLKEELESERTIRAKVEREKGDLVQDLEDLNERLEEAGG
                     TSLAQMEITKQQEARFQKLHHDMEETTRHFEATSASLKKRHAENLAELEGQVEHLQQV
                     RLVLEQDKSDLQLQVDDLLNRVDQMARAKANAEKLCGLYERRLNEANTKLDEVTQLAH
                     DLTTQKTKLQSESGEFFKRLEEKEALISQLSREKSNFTRQVEELRAQLEEESRSQSAL
                     SHALQSAKHDYDLLREQYEEEQEVKAELHRALSKGNKETVQWRAKYEHDAMQRTEDLE
                     EAKKKLAIRLQEAAEAMEVSNAKNASLERARHRLQLELGDALSDLGKARSVAAALGQK
                     QQHSDKALTSWKQKLDETQELLQASQKETRALSSEVLTFRQACEESTEAQETLKRQNQ
                     DLQEQICSLTNQVREGIKNLAEVEKAKKLIEQEKTEVQVRLEETEGALERNESKILRF
                     QLELSEAKAELERKLSEKEEEAERLREKHQQAMGSLQSNLDLEASSRIEATRLRKKME
                     GDLKEMEIQLCAANRQVSQMTRALGQLQGQMKDLHQQLDDSIYQNKDLKEQVALAEQR
                     TVLLQSELEELRTLQEQTERGRKLAEKELLEATERINLFHTQNTSLLSQKKKLEADVA
                     QVQKEAGEMLQACQKAEEKAKKTAAEAANMSEELKKEQDTNAHLERMRKNMEQTIKDL
                     QKRLDEAEQTAVLGSKKQIQKLESRVRDLEGELESEVRRSAEAQREARRLERGIKELT
                     YQAEEDKKNLSRMQALSDKLQLKVQSYKQQVEAAEAQANQYLSKYKKQQHELNEAKER
                     AEAAESQVNKLRAKAKELEKKVREE"
     exon            172..278
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            279..422
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            423..579
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            580..607
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            608..701
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            702..794
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            795..858
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            859..954
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1058
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1197
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1316
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1466
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1637
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1814
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1815..1947
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2015
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2016..2103
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2221
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2222..2345
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..2482
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2483..2738
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2739..2981
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            2982..3158
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            3159..3304
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            3305..3395
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            3396..3785
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            3786..3912
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            3913..4031
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            4032..4228
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            4229..4578
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            4579..4703
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            4704..4819
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            4820..5012
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5013..5216
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5217..5342
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5343..5513
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5514..5618
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5619..5714
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5715..5849
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
     exon            5850..6883
                     /gene="Myh15"
                     /gene_synonym="EG667772"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctttttgcag aacaaaccct ttcacattac ctgcagccct acattcccct gccctccatc
       61 atcccccagt gaatatttta agaacgatgg atctgtctga gtttggagat gccacagcct
      121 tcctcagaag aaataaagct gaccctctgt tccagccacc agcctttgat gggaagaaga
      181 aatgctgggt tcccgatggg aagaatgctt atattgaggc tgaggttaaa gaaagcggtg
      241 atgatggaca agtaattgta gagactagag atggagagat tatgagaatt aaggaggaca
      301 aacttcaaca gatgaaccct gaagagcttg aaatgataga agatctgtca atgctgcttt
      361 acctcaatga agcatctgta ctgcacaccc tgaggaggcg atatgaccat tggatgatct
      421 atacatattc aggtatcttc tgtgtggcta taaaccctta caagtggctc cctgtgtatc
      481 agaaagaggt catggctgcc tataaaagga agaggcgatc cgaggttccc cctcacatct
      541 ttgctgtggc caatcgtgcc tttcaggata tgcttcgcaa tggagagaac cagtctatag
      601 tcttcacagg agaatctggt tctggaaaga cagtgaacac caaactgatc attcagtatt
      661 ttgccaccat ggcagccata agtgagccta agaaaaagct ggggaattta gaagatcaaa
      721 ttgtaaaaat gaatcctctc ttagaagcat ttggaaatgc caaaactcag aaaaatgaca
      781 actcttcgcg ttttggaaaa ctcatccgga tacattttgg tgcaagaggg acactgtcat
      841 ttgcagatat tcagatctat tttcttgaaa aatctcgagt ggtttatcag cagcctggag
      901 agaggaacta ccatatcttt taccaaattc tgtctggaaa tcaagaactt cggaacatgc
      961 ttctggtgtc cacaaatccc tctgactttc atatttgctc ctgtggagtg gttgctgtgg
     1021 agagcctgga tgatgctaaa gaatttctgg ccacagaaaa agccatagat gtcttgggat
     1081 ttctacctga tgagaagttt gggtgctata agctcgttgg agccatcatg cactttggaa
     1141 acctgaagtt taaacggaat ctcagagagg aacaactgga ggctgatggc acagaaaatg
     1201 ctgacaaagc tgctttcctc atgggaattc acgcttctga gttgttaaaa ggcctaatat
     1261 atcctagaat caaagttggt aatgaatatg ttaccagaag tcaaaaccta caacaggtaa
     1321 cctatgcagt cggtgcactg tctcagtcaa tatatgagag gatgtttcag tggctagtgg
     1381 cacgcatgaa ccaagtcctg gacgccaagc tgacaagtca cttcttcgtt gggattcttg
     1441 acaccactgg ttttgaaata cttgattata atagtcttga gcaactctgc atcaatttta
     1501 ccaatgaaaa gttacaacag tttttcaatc agcaactgtt tattctggag caagaagaat
     1561 acaggaaaga gggccttgac tggctgtcca ttgactatgg tctggatgtg caagcctgca
     1621 tagatttcat tgagaagccc atgggcatct tttccatcct tgaagaggaa tgtatgcttc
     1681 ctaaagctac tgaccagatg ttcaagacca aactctttga ccaccatttt gggaagtcag
     1741 cttacttcca gacacccaca tctcctgaga agaactttga agttcacttt gaacttgctc
     1801 attatgcagg agtggtccct tataatatca gtggttggat tggaaagaac aaagggcttc
     1861 ttaatgaaac agtggtggct ctacttcaga agtcttccaa caaagtcctg gcgaatctct
     1921 ttacaaagga catcattgct ggtagtgctt cacagtttgg tgagaagaca cacaagaaag
     1981 gaacatcttt ccacttgatt acatctcttc ataaagagaa cataaataaa ttgatgacag
     2041 atttgaaatc aacagcacct cattttgtga gatgtataaa tcctaataag aacaaaattc
     2101 caggtgtaat ggatcctttc ttggttctcc agcagctgcg ctgtaatggt gtcttagaag
     2161 gcattagagt atgctgtgaa gcattcccaa gttggatgct atatgatgac tttaagcaaa
     2221 ggtactggat tctaaaccca agaatctttt caaagagcaa gtttgtgagc agcagaaaag
     2281 caactgaaga agtgcttgac ttcttggaga tagaccatcc ccattaccag tgtggagtca
     2341 ccaaggtgtt ttttaaagct ttcatcctgg accagttaga agaaagaagg gatgaaaaaa
     2401 tatctaaagt cttcactttg ttccaagcca gagcacgagg aaaacttatg cgcatcacat
     2461 tccagaagat tctagaagaa agggatgccc ttgctttgat ccaagagaac ataagagctt
     2521 tcattgctgt gaagaactgt ccctggatgg ggctcttctt caagatcaag ccccttgcta
     2581 agtctgtagg agctggagag gagatagctg gcctgaaaga agagtgtgca caactacaaa
     2641 aagctttgga gagttcagaa tcccagaggg aggagctgaa aacaaagcaa gtctcccttg
     2701 tccaagaaaa gaatgatcta cgtcttcagt tgcaggctga acaagaaacc ctggcaaatt
     2761 ccgaagagca gtgtgaatca ctgattaaat ccaaggtaga gctagaagtc aaaatcaagg
     2821 agctctctag gcaggtggag gaagaagagg agatcaattc tgagctgact gccaggggcc
     2881 ggaaactgga agatgaatgt tctgagttga agaaggaaat ctacgacctg gaagcaatac
     2941 tggcgaagtc agagaagggg aagtgtgcag cggagcacaa ggtcagaaac ctgacagagg
     3001 aggtgcactc tctaaatgag gaagtcagta aacttagtag agtagtgaag gatgctcagg
     3061 agacccagca acaaacccag gagcaacttc acatagagga ggaaaaactc agcaacatga
     3121 gcaaagcaaa cctgaagctg gcccagcaaa ttgatgtgtt ggaaggtgac cttgaacggg
     3181 agaggaaagc cagaatgaag tgtgagaggg agaagcgcaa gctgcaagat gagttaaaga
     3241 tgaaccagga gggtgctgag aatctggaga gcagccggca gaagctggca gagcagctga
     3301 ggaagaagga gtttgaaatg ggtcagatga attcaaaagt ggagaatgag aagaaccagg
     3361 tgtctcagct tcagaagatg gtgaaagagc ttcagactca tatattaaat ttgaaggagg
     3421 aactggaaag tgaaaggacc attagagcca aggtggaaag agagaaaggt gaccttgtcc
     3481 aagacctaga agatttgaat gagaggcttg aggaggcagg ggggaccagt ttggctcaga
     3541 tggagataac taagcaacag gaagcaagat ttcagaagct tcaccatgac atggaagaga
     3601 ccacaagaca ctttgaggca acctctgcct ctttgaaaaa gagacacgca gagaacctgg
     3661 ctgagcttga gggccaggta gaacatttac agcaggtcag gctggtgcta gaacaagaca
     3721 agagtgacct gcagcttcaa gtggatgacc tcctgaaccg cgttgatcag atggccagag
     3781 ctaaggcaaa tgctgagaaa ctctgtggtc tgtatgagag gcgcttgaat gaagcaaata
     3841 caaaactgga tgaggtgact cagttggcac atgatctgac gacacagaaa acaaagctac
     3901 agagtgagag tggtgagttc tttaaaagac tagaagaaaa ggaggccctg ataagccaac
     3961 tttccaggga aaagagcaac ttcactcggc aagttgaaga actgagagca cagctggagg
     4021 aggagagtag gtctcagagt gccctgagcc atgccctgca gtcagccaag catgactatg
     4081 atcttctgag agagcagtat gaagaagaac aagaagtcaa ggctgagctg caccgggctc
     4141 tatctaaagg caacaaggaa acagtgcagt ggagagcgaa gtatgaacat gatgctatgc
     4201 agagaactga agacttggag gaagccaaga agaagctggc gattcgattg caggaggctg
     4261 cagaagccat ggaggtgtcc aatgccaaga atgcctccct ggagcgggcc aggcacaggc
     4321 tccagctgga gctgggggat gccctttctg acctggggaa ggctcgctct gtggcagcgg
     4381 ctctggggca gaaacagcag cactctgaca aggcactgac ttcctggaag cagaagctgg
     4441 acgagaccca agagctgctg caggcttctc agaaggagac ccgggccctc agctctgagg
     4501 tcctcacctt caggcaagcc tgtgaggaga gcaccgaggc acaggagacc ttgaagaggc
     4561 agaaccagga ccttcaggaa cagatttgta gtctcacaaa ccaggtgaga gaagggatca
     4621 agaatttggc tgaagtggaa aaggccaaga agttgattga acaagagaag actgaagtcc
     4681 aagtgaggct ggaagaaaca gagggagctc tggaacggaa tgaaagcaag atccttcgtt
     4741 tccagctcga actctcagag gcgaaggcag agctggaaag gaagctgtcg gagaaagagg
     4801 aagaagcaga gaggctgagg gagaagcatc agcaagctat ggggtccctg cagtctaatt
     4861 tggatttgga agcttccagc agaattgagg ccaccagact gaggaagaag atggaagggg
     4921 acctcaagga aatggagatc cagctttgtg ctgccaaccg gcaggtgtca cagatgacca
     4981 gagccttggg ccagcttcag ggtcaaatga aggatcttca ccaacaactg gatgacagca
     5041 tttaccagaa caaagacctg aaggaacagg tggctctggc tgagcagcgc accgttcttc
     5101 ttcagtctga acttgaagag ctgaggacct tgcaggagca gacagagcgc gggagaaagc
     5161 tggccgaaaa ggagctccta gaagccacag aaagaatcaa tcttttccac acccagaaca
     5221 caagcctcct cagccagaag aagaaactgg aggccgatgt tgctcaggtg cagaaggaag
     5281 ctggagagat gttgcaggca tgtcagaagg cagaagaaaa ggccaaaaag acagctgctg
     5341 aggcagccaa catgtcagaa gagctgaaga aagaacaaga cactaatgct cacttggaga
     5401 ggatgaggaa gaacatggag cagacaatta aagacttgca gaaaaggctg gatgaagcag
     5461 aacagactgc tgtgctgggg agcaaaaagc aaatccagaa actggaatcc agggtgcggg
     5521 acctggaagg tgaactggag agtgaagtca ggcgcagtgc ggaagcccag cgggaagcac
     5581 gaagactgga gagaggcatc aaagagctga cctatcaggc agaggaagac aagaaaaatc
     5641 tgagcaggat gcaggctctg tctgataaac ttcagctgaa ggtgcagagt tacaaacagc
     5701 aagtggaagc agcggaggca caggctaatc aatacctttc caagtataag aagcagcaac
     5761 atgagctgaa tgaagccaag gagagggcag aggccgcaga atcgcaagtc aataaactca
     5821 gagctaaagc aaaggaactt gagaaaaagg ttcgagaaga ataaggagtt tctcttcatt
     5881 aaaaaaaaaa aagacaactg gaagcaagcc tttaagaaat aagtatgtgg caagaatagc
     5941 aggctaagga gatgatgaag aaaatgttct gatccaaagg actataacca cctcttggat
     6001 taatggatgg ctttttgatt ctcagtggca tgagacatct ctctactaca atttcacaca
     6061 aaagacttaa cagatgtaag aatcaatttt gatgttagaa gcaggcacac ttctcctttc
     6121 ctccatttct tcatgcatag cactcagaga agagccctta gtatatgctt catggagtct
     6181 ggtccatgat gaggaaggga tattcaagtt atctaacttt gcttaactgg tccctgtatt
     6241 tggtgacaat tgacaaaaat gtctcttagc actgtggagc aggcattgcc atagttaggt
     6301 gctttgaact tgtaggtaga ctatcctaat caagaaacat gtaggatcca cgcttatgtg
     6361 gactataacc tgagatgggt tgtacagttg tggccatgga gctaaggaag atgagcatgt
     6421 tctagaattt ctttccttgg atggttctag actaaagttg ggaacaagca aaaaaatctg
     6481 tcacagagtg agtagttaaa accagaggag tttctacttt atgtgcataa ggtcactata
     6541 gagccccaag cagtaggaca gttgaaaact attacttcag gcccaaggta agttctcagt
     6601 aaccagctac cttggacctt ttcttcccac ttcctgccag tctccttcaa cttggcaggc
     6661 atgaataaag ttctaaggca agcagcacca gcttcacctg gccatggcct agagactggg
     6721 cacgaggaca gtttggaaac agtctgtccc ttacaggatt gttccatcct cattgaaggc
     6781 aaagcccccc acccatccct gtgtgactca ctgcagccac ttgaggcaca gcggccacaa
     6841 ctgtgtaaag atgatgtctg acaataaatc ctgttctgtg tga
//
