LOCUS       NM_001271540            6457 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus myosin, heavy polypeptide 14 (Myh14), transcript
            variant 2, mRNA.
ACCESSION   NM_001271540
VERSION     NM_001271540.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6457)
  AUTHORS   Silverman,J.B., Krystofiak,E.E., Caplan,L.R., Lau,K.S. and
            Tyska,M.J.
  TITLE     Organization of a cytoskeletal superstructure in the apical domain
            of intestinal tuft cells
  JOURNAL   J Cell Biol 223 (12) (2024)
   PUBMED   39352498
REFERENCE   2  (bases 1 to 6457)
  AUTHORS   Huycke,T.R., Hakkinen,T.J., Miyazaki,H., Srivastava,V., Barruet,E.,
            McGinnis,C.S., Kalantari,A., Cornwall-Scoones,J., Vaka,D., Zhu,Q.,
            Jo,H., Oria,R., Weaver,V.M., DeGrado,W.F., Thomson,M.,
            Garikipati,K., Boffelli,D., Klein,O.D. and Gartner,Z.J.
  TITLE     Patterning and folding of intestinal villi by active mesenchymal
            dewetting
  JOURNAL   Cell 187 (12), 3072-3089 (2024)
   PUBMED   38781967
REFERENCE   3  (bases 1 to 6457)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 6457)
  AUTHORS   Jun,S., Angueira,A.R., Fein,E.C., Tan,J.M.E., Weller,A.H.,
            Cheng,L., Batmanov,K., Ishibashi,J., Sakers,A.P., Stine,R.R. and
            Seale,P.
  TITLE     Control of murine brown adipocyte development by GATA6
  JOURNAL   Dev Cell 58 (21), 2195-2205 (2023)
   PUBMED   37647897
REFERENCE   5  (bases 1 to 6457)
  AUTHORS   Lee,L.A., Broadwell,L.J., Buvoli,M. and Leinwand,L.A.
  TITLE     Nonproductive Splicing Prevents Expression of MYH7b Protein in the
            Mammalian Heart
  JOURNAL   J Am Heart Assoc 10 (14), e020965 (2021)
   PUBMED   34227390
  REMARK    GeneRIF: Nonproductive Splicing Prevents Expression of MYH7b
            Protein in the Mammalian Heart.
REFERENCE   6  (bases 1 to 6457)
  AUTHORS   Bao,J., Jana,S.S. and Adelstein,R.S.
  TITLE     Vertebrate nonmuscle myosin II isoforms rescue small interfering
            RNA-induced defects in COS-7 cell cytokinesis
  JOURNAL   J Biol Chem 280 (20), 19594-19599 (2005)
   PUBMED   15774463
  REMARK    Erratum:[J Biol Chem. 2006 Apr 14;281(15):10652]
REFERENCE   7  (bases 1 to 6457)
  AUTHORS   Marigo,V., Nigro,A., Pecci,A., Montanaro,D., Di Stazio,M.,
            Balduini,C.L. and Savoia,A.
  TITLE     Correlation between the clinical phenotype of MYH9-related disease
            and tissue distribution of class II nonmuscle myosin heavy chains
  JOURNAL   Genomics 83 (6), 1125-1133 (2004)
   PUBMED   15177565
REFERENCE   8  (bases 1 to 6457)
  AUTHORS   Ma,X., Kawamoto,S., Hara,Y. and Adelstein,R.S.
  TITLE     A point mutation in the motor domain of nonmuscle myosin II-B
            impairs migration of distinct groups of neurons
  JOURNAL   Mol Biol Cell 15 (6), 2568-2579 (2004)
   PUBMED   15034141
REFERENCE   9  (bases 1 to 6457)
  AUTHORS   Golomb,E., Ma,X., Jana,S.S., Preston,Y.A., Kawamoto,S.,
            Shoham,N.G., Goldin,E., Conti,M.A., Sellers,J.R. and Adelstein,R.S.
  TITLE     Identification and characterization of nonmuscle myosin II-C, a new
            member of the myosin II family
  JOURNAL   J Biol Chem 279 (4), 2800-2808 (2004)
   PUBMED   14594953
REFERENCE   10 (bases 1 to 6457)
  AUTHORS   Buxton,D.B., Golomb,E. and Adelstein,R.S.
  TITLE     Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW
            264.7 mouse macrophages
  JOURNAL   J Biol Chem 278 (17), 15449-15455 (2003)
   PUBMED   12598534
  REMARK    GeneRIF: a cGMP-independent mechanism for nitric oxide-mediated
            inhibition of nonmuscle myosin heavy chain II-C induction
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC150895.2 and AC157653.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, has
            multiple differences in the coding region but maintains the reading
            frame, compared to variant 1. This variant encodes isoform 2, which
            is shorter than isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY363100.1, SRR10223971.7518.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                AC150895.2         99703-99746
            45-440              AC150895.2         105046-105441
            441-597             AC150895.2         109482-109638
            598-625             AC150895.2         112305-112332
            626-728             AC150895.2         112509-112611
            729-752             AC150895.2         113106-113129
            753-845             AC150895.2         114862-114954
            846-909             AC150895.2         115261-115324
            910-1008            AC157653.2         2-100
            1009-1149           AC157653.2         1485-1625
            1150-1245           AC157653.2         10497-10592
            1246-1364           AC157653.2         12877-12995
            1365-1517           AC157653.2         14668-14820
            1518-1691           AC157653.2         14940-15113
            1692-1865           AC157653.2         15593-15766
            1866-1980           AC157653.2         16177-16291
            1981-2168           AC157653.2         19510-19697
            2169-2290           AC157653.2         20460-20581
            2291-2360           AC157653.2         21052-21121
            2361-2521           AC157653.2         21513-21673
            2522-2630           AC157653.2         22397-22505
            2631-2762           AC157653.2         23211-23342
            2763-2969           AC157653.2         23993-24199
            2970-3107           AC157653.2         24659-24796
            3108-3231           AC157653.2         25168-25291
            3232-3403           AC157653.2         25417-25588
            3404-3616           AC157653.2         26832-27044
            3617-3761           AC157653.2         28548-28692
            3762-3968           AC157653.2         28884-29090
            3969-4073           AC157653.2         29632-29736
            4074-4226           AC157653.2         29826-29978
            4227-4475           AC157653.2         30832-31080
            4476-4688           AC157653.2         32106-32318
            4689-4901           AC157653.2         37744-37956
            4902-5063           AC157653.2         38550-38711
            5064-5192           AC157653.2         39635-39763
            5193-5281           AC157653.2         40326-40414
            5282-5405           AC157653.2         40498-40621
            5406-5614           AC157653.2         42325-42533
            5615-5723           AC157653.2         45513-45621
            5724-5896           AC157653.2         47253-47425
            5897-6457           AC157653.2         47693-48253
FEATURES             Location/Qualifiers
     source          1..6457
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.85 cM"
     gene            1..6457
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /note="myosin, heavy polypeptide 14"
                     /db_xref="GeneID:71960"
                     /db_xref="MGI:MGI:1919210"
     exon            1..44
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            45..440
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            441..597
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            598..625
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            626..728
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            729..752
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            753..845
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            846..909
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1008
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1149
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1245
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1246..1364
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1517
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1691
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1692..1865
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1980
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2168
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2290
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2291..2360
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2361..2521
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2522..2630
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2631..2762
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2763..2969
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            2970..3107
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            3108..3231
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            3232..3403
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            3404..3616
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            3617..3761
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            3762..3968
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            3969..4073
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            4074..4226
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            4227..4475
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            4476..4688
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            4689..4901
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            4902..5063
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5064..5192
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5193..5281
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5282..5405
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5406..5614
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5615..5723
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5724..5896
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     exon            5897..6457
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6436..6441
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /note="hexamer: AATAAA"
     polyA_site      6457
                     /gene="Myh14"
                     /gene_synonym="2400004E04Rik; II-C; NHMCII; NMHC II-C"
                     /note="major polyA site"
ORIGIN      
        1 ccttttctgt ccaggccgag gcctctggac cgccctgggc gccgaccatg gctgcagtga
       61 ccatgtccgt gtctgggagg aaggtagcct ccaggccagg cccggtgcct gaggcagccc
      121 aatcgttcct ctacgcgccc cggacgccaa atgtaggtgg ccctggaggg ccacaggtgg
      181 agtggacagc ccggcgcatg gtgtgggtgc cctcggaact gcatgggttc gaggcagcag
      241 ccctgcggga tgaaggggag gaggaggcag aagtggagct ggcggagagt gggcgccgcc
      301 tgcggctgcc cagggaccag atccagcgca tgaacccacc caagttcagc aaggcagaag
      361 atatggctga gctcacctgc ctcaacgagg cctcggtcct gcacaacctg cgagaacgct
      421 actactccgg gctcatttat acctactctg gcctcttctg tgtggtcatt aacccataca
      481 agcagctgcc catctacacg gaggccattg ttgaaatgta ccggggcaag aagcgccatg
      541 aggtgccacc tcacgtgtat gctgtgacgg agggcgcgta ccgcagcatg cttcaggatc
      601 gtgaggatca atccattctc tgcacgggag agtctggcgc tgggaagacg gagaacacca
      661 agaaggtcat ccagtacctg gcccatgtgg catcatctcc aaagggcagg aaggagcctg
      721 gtgtccctgc ctccgtcagc accatgtctt atggggagct agagcgtcag cttcttcaag
      781 ccaaccccat cctagaagcc tttggcaatg ccaagacggt gaagaacgac aactcttccc
      841 gatttggcaa attcatccgc atcaactttg atattgctgg ctacatcgtg ggagcaaaca
      901 tcgagaccta tctgttggag aagtcccggg ccatcagaca ggccaaggat gaatgcagct
      961 tccatatctt ctaccagctg ctagggggcg ctggggagca gctaaaagct gacctccttc
     1021 tggagccctg ttcccattat cgcttcctga ccaatgggcc ctcatcgtcc ccgggccagg
     1081 agcgtgagtt attccaggag accctggagt ccctgcgtgt gctgggcctc ctcccagaag
     1141 agatcactgc catgctgcgc actgtctctg ctgtcctcca gtttggcaac attgtcctga
     1201 agaaagagcg caatacggac caagccacca tgcctgacaa cacagctgcc cagaagcttt
     1261 gccgcctctt gggactcgga gtgaccgact tctccagagc ccttctcaca ccccgcatca
     1321 aagtgggccg agattatgtt cagaaagcac aaaccaagga gcaggctgac tttgcgctgg
     1381 aggctctggc caaagctacc tatgagcgcc tgttccgctg gctggttctg cggctcaacc
     1441 gtgccctgga cagaagcccg cggcagggtg cctccttcct gggcatcctg gacatcgcgg
     1501 gctttgagat cttccagctg aactccttcg agcagctgtg catcaactac accaacgaga
     1561 agctacagca gctattcaac cacaccatgt tcgtgctgga gcaggaggag taccagcgag
     1621 agggcatccc ctggaccttc ctagacttcg ggttggacct gcaaccttgc atcgacctca
     1681 ttgagcgtcc ggccaaccct ccaggtctcc tggccctgct ggacgaggag tgctggttcc
     1741 ccaaggccac ggacaagtct tttgtggaga aggttgccca ggagcagggc agccacccca
     1801 agttccagcg ccccaggaac ctgcgagatc aggccgactt cagcgtcctg cactatgccg
     1861 gcaaggttga ctacaaagcc agtgagtggc tgatgaagaa catggaccca ctgaatgaca
     1921 atgtggccgc cttgcttcac cagagcacgg atcgtctcac agctgagatc tggaaggatg
     1981 tggagggcat cgtggggctg gagcaagtaa gcagccttgg agatggccca ccgggaggcc
     2041 gcccccgccg tggaatgttc cggactgtgg ggcagctcta caaagaatcc ctgagccgcc
     2101 tcatggccac gctcagcaac accaacccta gttttgtccg ctgcatcgtt cccaatcatg
     2161 agaagagggc tggaaagctg gagccgcgcc tggtgctgga ccaactccgt tgtaacgggg
     2221 tcctcgaggg tatccgcatc tgtcgccaag gcttccccaa ccgcatcctc ttccaggagt
     2281 tccgacagcg ctatgaaatc ctcaccccga acgctattcc caagggcttc atggacggca
     2341 aacaggcctg tgagaagatg atccaggccc tggagctaga ccccaacctg taccgtgttg
     2401 gccaaagcaa gatcttcttc cgggcagggg tcctggccca gctggaggag gagcgggacc
     2461 tgaaagtcac cgacatcata gtgtctttcc aggcagcggc acggggctac ctggcccgta
     2521 gggctttcca gagacggcag cagcagcaga gtgctctgag ggtgatgcag agaaactgtg
     2581 ctgcctacct caagctcagg aactggcagt ggtggaggct gttcatcaag gtgaagcccc
     2641 tgctgcaggt gacacggcag gatgaggtgc tgcaggcgcg cgcccaggag ctgcagaaag
     2701 ttcaggagct gcagcagcag agcgctcgtg aagtggggga actgcagggt cgagtggcac
     2761 agctagagga ggagcgcacg cgcctggctg agcagcttcg agcagaagcc gagctctgct
     2821 ctgaggccga ggagacgcgg gcgcgactgg ctgcccggaa gcaggagctg gagctggtgg
     2881 tgacagagct ggaggcacga gtgggcgagg aagaagagtg cagccggcag ctgcagagtg
     2941 agaagaagag gctgcagcag catatccagg agctagagag ccacctggaa gctgaggagg
     3001 gtgcccggca gaagctacag ctggagaagg tgaccacaga ggccaagatg aagaaatttg
     3061 aggaggacct gctgctcctg gaggaccaga attccaagct gagcaaggag cggaggctgc
     3121 tggaggagcg gctggctgag ttctcctcac aggcagcaga agaggaagag aaagtcaaaa
     3181 gtctcaacaa gctgaggctc aaatatgaag ccacaatctc agacatggaa gaccggctga
     3241 agaaggagga gaagggacgc caggaactag agaagctgaa gcgacggctg gacggggaga
     3301 gctcagagct tcaggagcag atggtggagc agaagcagag ggcagaggaa ctgctcgcac
     3361 agctgggccg caaggaggat gagctgcagg ccgccctgct cagggcagag gaagagggtg
     3421 gtgcccgtgc ccagttgctc aagtccctgc gagaggcaca ggctggcctt gctgaggctc
     3481 aggaggacct ggaagctgag cgggtagcca gggccaaggc ggagaagcag cgccgggacc
     3541 tgggcgagga gttggaggcc ctacgtgggg agctcgagga cactctggat tccaccaacg
     3601 cccagcagga gctgcggtcc aagagggagc aggaggtgac agagctgaag aaagcattgg
     3661 aagaggagtc ccgtgcccat gaggtgtcca tgcaggagct gagacagagg catagccagg
     3721 cactggtgga gatggccgag cagttggagc aagcccggag gggcaaaggt gtgtgggaga
     3781 agactcggct atccctggag gctgaggtgt ccgagctgaa ggccgagctg agcagcctgc
     3841 agacctcgag acaggagggt gagcagaaga ggcgccgcct ggagtcccag ctacaggagg
     3901 tccagggccg atccagtgat tcggagcggg ctcggtctga ggctgctgag aagctgcaga
     3961 gagcccaggc ggaacttgag agcgtgtcca cagccctgag tgaggcggag tccaaagcca
     4021 tcaggctggg caaggagctg agcagtgcag agtcccagct gcatgacacc caggaactgc
     4081 ttcaggagga gaccagggca aagctggcct tggggtcccg tgtgcgtgcc ctagaggccg
     4141 aggcggcggg gcttcgggag cagatggaag aggaggtggt tgccagggaa cgggctggcc
     4201 gggagctgca gagcacgcag gcccagctct ctgaatggcg gcgccgccag gaagaagagg
     4261 ccgcggtgct ggaggctggg gaggaggctc ggcgccgtgc agcccgggag gcagagaccc
     4321 tgacccagcg cctggcagaa aagactgagg ctgtagaacg actggagcga gcccggcgcc
     4381 gactgcagca ggagttggac gatgccactg tggatctggg gcagcagaag cagctcctga
     4441 gcacactgga gaagaagcag cggaaatttg accagctcct ggcagaggag aaggctgcag
     4501 ttctacgggc tgtggaagac cgtgaacgga tagaggccga aggccgggag cgagaggccc
     4561 gggccctgtc gctgacccgg gccctggaag aggagcagga ggcccgggag gagctggaga
     4621 ggcagaaccg tgctctgagg gctgagctgg aagcactgct gagcagcaag gatgacgtgg
     4681 gcaagaacgt gcacgagctg gagcgagccc gtaaggcggc tgaacaggca gccagtgacc
     4741 tgcggacaca ggtgacagaa ttggaggatg agctgacagc cgcagaggat gccaagctgc
     4801 gcctggaggt gactgtgcag gctctgaagg ctcaacatga acgcgacctg cagggccgcg
     4861 atgatgccgg tgaggagagg cggaggcagc tggccaagca gctaagagac gcagaggtag
     4921 agcgcgatga ggaacggaag cagagggcac tggctatggc tgcccgcaag aagctggagc
     4981 tggaactgga ggagttgaag gcgcagacat ctgctgctgg gcagggcaag gaagaggcag
     5041 tgaagcagct gaagaagatg caggtccaga tgaaggagct gtggcgggag gtagaggaga
     5101 cgcgtagctc ccgcgacgag atgtttaccc tgagcaggga aaatgagaag aagctcaagg
     5161 ggctggaagc tgaggtgctg cgtctgcaag aggaacttgc tgcctcagac cgagcccgga
     5221 ggcaggccca gcaagacaga gacgagatgg cagaggaggt ggccagtggc aatcttagca
     5281 aggcagccac cctggaggaa aaacggcagc tggaggggcg actgagccag ttggaagagg
     5341 agctggagga agaacagaac aactcggagc tgctcaagga ccattaccga aagctagtgc
     5401 tacaggtcga gtccctcacc acagaactgt ctgccgaacg aagtttctca gccaaggccg
     5461 agagtggacg gcagcagctg gagcggcaga tccaggaact gcgggcccgc ttgggtgaag
     5521 aggatgctgg agcccgagcc aggcagaaaa tgctgatcgc tgctctggag tctaaactgg
     5581 cccaggcaga ggagcagctg gagcaggaga gcagggagcg catcctctct ggcaagctgg
     5641 tacgcagagc tgagaagcgg ctgaaggagg tagttcttca ggtggatgaa gagcgcaggg
     5701 tggctgacca ggtccgggac cagctggaga aaagcaacct ccggctgaag cagctcaaga
     5761 ggcagctgga ggaggcagag gaggaggcat ctcgggcaca ggctggtcgg aggcggctgc
     5821 agcgggagct ggaggacgtc actgagtctg cagaatccat gaaccgggag gtgaccacgc
     5881 tgaggaacag gctccggcgt ggcccactta cattcaccac acggactgtg cgccaggtgt
     5941 tccggctgga agagggcgtg gcttctgacg aggaagaggc tgaaggagct gaacctggct
     6001 ctgcaccagg ccaggagccg gaggctccgc cccctgccac accccaatga tccagtctgt
     6061 cctagatgcc ccaaggacag agccctttcc agtgcccctc ctggtttgca ctttgaaatg
     6121 gcactgtcct ctggcacttt ctggcattga tgaaccctcc tgggacccca ggacccctgc
     6181 ccactggggg ccccaaacca aggagctggg tgggagggag gccatgatgg tctctcttgt
     6241 tagagaaaca aaattgaacg tggatgtcaa gaatgtcctg tctgcaccta ttttcagcag
     6301 gcctgtcccc tggagagggc aggcagggtg cttccatccc ctctcagtat cttgccctct
     6361 tttttggggg gaagtggggt gtctgtgtgc tcatagggta atgctcatgg cccctcatgc
     6421 tccagacact aaagaaataa actggctgga cccttca
//
