LOCUS       NM_001402795            6564 bp    mRNA    linear   ROD 13-DEC-2024
DEFINITION  Mus musculus myosin, heavy polypeptide 11, smooth muscle (Myh11),
            transcript variant 3, mRNA.
ACCESSION   NM_001402795 XM_006521843
VERSION     NM_001402795.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6564)
  AUTHORS   Patel,V.N., Aure,M.H., Choi,S.H., Ball,J.R., Lane,E.D., Wang,Z.,
            Xu,Y., Zheng,C., Liu,X., Martin,D., Pailin,J.Y., Prochazkova,M.,
            Kulkarni,A.B., van Kuppevelt,T.H., Ambudkar,I.S., Liu,J. and
            Hoffman,M.P.
  TITLE     Specific 3-O-sulfated heparan sulfate domains regulate salivary
            gland basement membrane metabolism and epithelial differentiation
  JOURNAL   Nat Commun 15 (1), 7584 (2024)
   PUBMED   39217171
  REMARK    Erratum:[Nat Commun. 2024 Oct 10;15(1):8784. doi:
            10.1038/s41467-024-53230-4. PMID: 39389981]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6564)
  AUTHORS   Wang,L., He,X., Hu,G., Liu,J., Kang,X., Yu,L., Dong,K., Zhao,J.,
            Zhang,A., Zhang,W., Brands,M.W., Su,H., Zheng,Z. and Zhou,J.
  TITLE     A novel mouse model carrying a gene trap insertion into the Hmgxb4
            gene locus to examine Hmgxb4 expression in vivo
  JOURNAL   Physiol Rep 12 (8), e16014 (2024)
   PUBMED   38644513
REFERENCE   3  (bases 1 to 6564)
  AUTHORS   Xu,Z., Wang,W., Yang,T., Li,L., Ma,X., Chen,J., Wang,J., Huang,Y.,
            Gould,J., Lu,H., Du,W., Sahu,S.K., Yang,F., Li,Z., Hu,Q., Hua,C.,
            Hu,S., Liu,Y., Cai,J., You,L., Zhang,Y., Li,Y., Zeng,W., Chen,A.,
            Wang,B., Liu,L., Chen,F., Ma,K., Xu,X. and Wei,X.
  TITLE     STOmicsDB: a comprehensive database for spatial transcriptomics
            data sharing, analysis and visualization
  JOURNAL   Nucleic Acids Res 52 (D1), D1053-D1061 (2024)
   PUBMED   37953328
REFERENCE   4  (bases 1 to 6564)
  AUTHORS   Russell,N.X., Burra,K., Shah,R.M., Bottasso-Arias,N.,
            Mohanakrishnan,M., Snowball,J., Ediga,H.H., Madala,S.K. and
            Sinner,D.
  TITLE     Wnt signaling regulates ion channel expression to promote smooth
            muscle and cartilage formation in developing mouse trachea
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 325 (6), L788-L802 (2023)
   PUBMED   37873566
REFERENCE   5  (bases 1 to 6564)
  AUTHORS   Rao,J., Djeffal,Y., Chal,J., Marchiano,F., Wang,C.H., Al
            Tanoury,Z., Gapon,S., Mayeuf-Louchart,A., Glass,I., Sefton,E.M.,
            Habermann,B., Kardon,G., Watt,F.M., Tseng,Y.H. and Pourquie,O.
  TITLE     Reconstructing human brown fat developmental trajectory in vitro
  JOURNAL   Dev Cell 58 (21), 2359-2375 (2023)
   PUBMED   37647896
REFERENCE   6  (bases 1 to 6564)
  AUTHORS   Suzuki,T., Kim,H.S., Kurabayashi,M., Hamada,H., Fujii,H.,
            Aikawa,M., Watanabe,M., Watanabe,N., Sakomura,Y., Yazaki,Y. and
            Nagai,R.
  TITLE     Preferential differentiation of P19 mouse embryonal carcinoma cells
            into smooth muscle cells. Use of retinoic acid and antisense
            against the central nervous system-specific POU transcription
            factor Brn-2
  JOURNAL   Circ Res 78 (3), 395-404 (1996)
   PUBMED   8593698
REFERENCE   7  (bases 1 to 6564)
  AUTHORS   Doggett,N.A. and Callen,D.F.
  TITLE     Report and abstracts of the third international workshop on human
            chromosome 16 mapping 1994. Pittsburgh, Pennsylvania, May 7-9, 1994
  JOURNAL   Cytogenet Cell Genet 68 (3-4), 165-184 (1995)
   PUBMED   7842732
REFERENCE   8  (bases 1 to 6564)
  AUTHORS   Miano,J.M., Cserjesi,P., Ligon,K.L., Periasamy,M. and Olson,E.N.
  TITLE     Smooth muscle myosin heavy chain exclusively marks the smooth
            muscle lineage during mouse embryogenesis
  JOURNAL   Circ Res 75 (5), 803-812 (1994)
   PUBMED   7923625
REFERENCE   9  (bases 1 to 6564)
  AUTHORS   Deng,Z., Liu,P., Marlton,P., Claxton,D.F., Lane,S., Callen,D.F.,
            Collins,F.S. and Siciliano,M.J.
  TITLE     Smooth muscle myosin heavy chain locus (MYH11) maps to
            16p13.13-p13.12 and establishes a new region of conserved synteny
            between human 16p and mouse 16
  JOURNAL   Genomics 18 (1), 156-159 (1993)
   PUBMED   8276405
REFERENCE   10 (bases 1 to 6564)
  AUTHORS   Matsuoka,R., Yoshida,M.C., Furutani,Y., Imamura,S., Kanda,N.,
            Yanagisawa,M., Masaki,T. and Takao,A.
  TITLE     Human smooth muscle myosin heavy chain gene mapped to chromosomal
            region 16q12
  JOURNAL   Am J Med Genet 46 (1), 61-67 (1993)
   PUBMED   7684189
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164291.2.
            
            On Mar 23, 2022 this sequence version replaced XM_006521843.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.18081.1,
                                           SRR10223971.15720.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                AC164291.2         170268-170355       c
            89-449              AC164291.2         156544-156904       c
            450-606             AC164291.2         148101-148257       c
            607-634             AC164291.2         135477-135504       c
            635-737             AC164291.2         129514-129616       c
            738-758             AC164291.2         127572-127592       c
            759-851             AC164291.2         125719-125811       c
            852-915             AC164291.2         124493-124556       c
            916-1014            AC164291.2         123797-123895       c
            1015-1158           AC164291.2         118388-118531       c
            1159-1254           AC164291.2         115361-115456       c
            1255-1373           AC164291.2         113345-113463       c
            1374-1526           AC164291.2         112532-112684       c
            1527-1700           AC164291.2         111517-111690       c
            1701-1874           AC164291.2         109685-109858       c
            1875-1989           AC164291.2         107728-107842       c
            1990-2183           AC164291.2         105451-105644       c
            2184-2305           AC164291.2         102970-103091       c
            2306-2375           AC164291.2         102808-102877       c
            2376-2536           AC164291.2         102488-102648       c
            2537-2645           AC164291.2         100736-100844       c
            2646-2777           AC164291.2         99147-99278         c
            2778-2984           AC164291.2         98852-99058         c
            2985-3122           AC164291.2         97832-97969         c
            3123-3246           AC164291.2         96934-97057         c
            3247-3418           AC164291.2         94728-94899         c
            3419-3631           AC164291.2         91510-91722         c
            3632-3776           AC164291.2         90218-90362         c
            3777-3983           AC164291.2         88503-88709         c
            3984-4088           AC164291.2         87224-87328         c
            4089-4241           AC164291.2         86981-87133         c
            4242-4490           AC164291.2         86532-86780         c
            4491-4703           AC164291.2         84903-85115         c
            4704-4916           AC164291.2         84493-84705         c
            4917-5078           AC164291.2         84099-84260         c
            5079-5207           AC164291.2         83623-83751         c
            5208-5296           AC164291.2         83317-83405         c
            5297-5420           AC164291.2         82105-82228         c
            5421-5629           AC164291.2         81055-81263         c
            5630-5738           AC164291.2         79961-80069         c
            5739-5911           AC164291.2         79687-79859         c
            5912-6564           AC164291.2         73524-74176         c
FEATURES             Location/Qualifiers
     source          1..6564
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 9.71 cM"
     gene            1..6564
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /note="myosin, heavy polypeptide 11, smooth muscle"
                     /db_xref="GeneID:17880"
                     /db_xref="MGI:MGI:102643"
     exon            1..88
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            89..449
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            450..606
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            607..634
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            635..737
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            738..758
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            759..851
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            852..915
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1014
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1158
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1254
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1373
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1526
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1700
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1701..1874
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..1989
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            1990..2183
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2184..2305
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2306..2375
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2376..2536
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2645
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2777
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2778..2984
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3122
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            3123..3246
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            3247..3418
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            3419..3631
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            3632..3776
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            3777..3983
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            3984..4088
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            4089..4241
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            4242..4490
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            4491..4703
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            4704..4916
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            4917..5078
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5079..5207
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5208..5296
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5297..5420
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5421..5629
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5630..5738
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5739..5911
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     exon            5912..6564
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6543..6548
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /note="hexamer: AATAAA"
     polyA_site      6564
                     /gene="Myh11"
                     /gene_synonym="SM1; SM2; smMHC"
                     /note="major polyA site"
ORIGIN      
        1 agatttggac catcccagcc tgggatcagt gccagatccg agctctccat ccggtgtcct
       61 cctgctaatc cacccccgga gtagatctgg gaccaccaga catcatggcg cagaaagggc
      121 agctcagcga tgatgagaag ttcctctttg tggataaaaa cttcatgaac agcccaatgg
      181 ctcaggccga ctgggtagcc aagaagctgg tgtgggtccc ttcagagaag cagggcttcg
      241 aagcagccag catcaaggag gagaagggcg atgaggtggt cgtggagttg gtggaaaatg
      301 gaaagaaggt cacagttggc aaagatgaca tccaaaaaat gaacccaccc aagttctcta
      361 aggtggagga catggcagag ctgacgtgcc tcaatgaggc ctctgtgctg cacaacctga
      421 gggagcgata cttctcaggc ctcatctata cctactctgg cctcttctgt gtggtggtca
      481 acccctacaa gtacctaccc atctactcag aaaagatcgt ggatatgtac aagggcaaga
      541 agaggcatga gatgccgcct cacatctatg ccattgccga cacagcctac agaagcatgc
      601 tacaagatcg tgaagaccag tccattctgt gcacaggtga gtctggagcc ggaaagacag
      661 agaacacaaa gaaagtcata cagtacttgg ctgtggtggc atcctcccac aagggcaaga
      721 aagacagcag catcacgcaa ggtccatctt ttgcctacgg ggagctggaa aagcagcttc
      781 tacaggcaaa cccaatcctg gaggctttcg gcaatgcgaa aaccgtcaag aacgacaact
      841 cctctcgctt tggcaagttc attcgcatca acttcgatgt cactggttac attgtaggtg
      901 ccaatattga aacatatctt ctggaaaagt ctagggctat tcgacaggct agggatgaga
      961 gaacatttca catcttctac tacctgctcg ccggagccaa ggaaaagatg aaaagtgacc
     1021 tgcttttgga gagcttcaac agctacacat ttttatccaa tggctttgtg cccatcccag
     1081 ctgcacaaga tgatgagatg ttccaggaga cactggaagc catgtctatc atgggcttca
     1141 atgaagagga acagctagcc atcttgaagg tagtatcatc tgtccttcag cttggaaaca
     1201 ttgtcttcaa gaaggagcga aacacagacc aggcatccat gcctgataac acagcggctc
     1261 agaaagtttg ccacctcgtg gggattaatg tgacagattt cactagagcc atcctgaccc
     1321 cacgtatcaa agttggacgg gatgtggtgc agaaggctca gaccaaagaa caggctgact
     1381 ttgccatcga ggccttagcc aaggccacct atgagcgcct tttccgatgg attctcagcc
     1441 gtgtaaacaa ggccttggac aagacccatc ggcagggggc ctccttcctg ggcattctgg
     1501 atattgctgg gtttgaaatc tttgaggtaa actccttcga gcagctgtgc atcaactaca
     1561 ccaacgagaa gctgcagcag ctgttcaacc acacgatgtt catcctggag caggaagagt
     1621 accagcgaga gggcatcgag tggaacttca tcgacttcgg cctggacctg cagccttgta
     1681 ttgagctgat tgagcggccg aacaaccctc ccggtgtgct ggccctgctg gatgaagaat
     1741 gctggttccc caaagctaca gacaagtctt ttgtggagaa gctatgctca gagcagggaa
     1801 atcaccccaa atttcagaag cccaagcagc taaaggacaa aacagagttc tccatcatcc
     1861 actatgctgg gaaggtggac tacaatgcaa gtgcctggct gaccaagaac atggacccgc
     1921 taaatgacaa tgtgacatca ctcctcaatg cctcctctga caagtttgtg gctgacctgt
     1981 ggaaggatgt ggaccgcatt gtggggctgg accagatggc caagatgact gagagctcac
     2041 tgcccagtgc ctccaagacc aaaaagggca tgttccgcac cgtgggccag ctctacaaag
     2101 agcagttggg gaaactgatg actacactgc gcaataccac gcctaacttt gtgcgctgca
     2161 tcatccccaa ccatgagaag aggtctggca agctggatgc atttctagtg ctggaacagc
     2221 tgcgctgcaa cggtgtgttg gaaggcatcc gcatctgccg tcagggcttc cccaacagga
     2281 ttgtcttcca agagttccgg caacgctatg agatcctggc agcgaacgcc atccccaaag
     2341 gcttcatgga tggaaagcaa gcctgcattc tcatgatcaa agccctcgaa cttgacccta
     2401 acctgtacag gattgggcag agcaaaatct tcttccgaac gggggtcctg gcccacctag
     2461 aggaggaacg agacctgaaa attactgatg tcatcatggc cttccaggca atgtgtcgtg
     2521 gctaccttgc cagaaaggcc ttcaccaaga ggcagcaaca gctgacagcc atgaaggtga
     2581 tccagaggaa ctgcgctgcc taccttaagc tccgcaactg gcaatggtgg cggctcttca
     2641 ccaaagtaaa gccattgctc caggtgacac ggcaggagga ggagatgcag gccaaggagg
     2701 aggagatgca aaagatcaag gagcggcagc agaaggcaga gactgagttg aaggagctgg
     2761 agcagaagca cactcagctg gctgaggaga agactctgct gcaggagcag ttgcaggcag
     2821 agacagagct gtatgctgag gctgaggaga tgcgggtccg gttggcagcc aagaagcagg
     2881 aactggagga gatcctacat gagatggagg cccgcctgga ggaagaggaa gaccggggcc
     2941 agcaactaca ggctgagagg aagaagatgg ctcagcagat gctagacctg gaggagcaac
     3001 tggaggagga agaggccgcc agacagaaac tacagctaga gaaggtcacg gctgaggcca
     3061 agatcaagaa actggaggat gacatcttgg ttatggatga tcagaacagt aaactttcaa
     3121 aagaacgaaa actccttgaa gagagggtca gcgacttgac aaccaaccta gcagaagagg
     3181 aagaaaaggc taaaaacctc acaaagctga agagcaagca tgagtctatg atctcagagc
     3241 tggaggtgag gctgaagaaa gaggagaaga gccggcagga gctggagaaa ctcaagagga
     3301 aactggaggg tgatgccagt gacttccatg agcagatcgc tgacttgcag gcccagattg
     3361 cagagctcaa gatgcagctg gcaaagaaag aggaagagct acaggcagct ctagccaggc
     3421 ttgatgaaga gatcgcccag aaaaacaatg ccctaaagaa gattcgcgag ctagagggcc
     3481 atatctcaga cctacaagag gacctagact cagagcgggc tgccaggaac aaggccgaga
     3541 agcagaagcg agacctgggg gaggagctgg aggcactcaa gacggagctg gaggatacgc
     3601 tggacagcac agctacccag caggagctca gagccaagag ggaacaggag gtgacagtgc
     3661 tgaagaaggc cctggatgag gagacgcggt cccatgaggc ccaggtccag gagatgaggc
     3721 agaagcacac acaggcagtg gaggaactca cagagcagct ggagcagttc aaaagggcca
     3781 aggcaaacct ggacaaaagc aagcagacac tggagaagga gaacgcggac ctggctgggg
     3841 agctgcgtgt cctgggccag gcgaagcagg aggtggaaca caagaagaag aagctggagg
     3901 tgcagctgca ggatctgcag tccaagtgca gtgatgggga gcgtgcccgg gctgagctca
     3961 gtgacaaggt ccacaagcta cagaatgaag tggagagtgt cactggcatg ctcaatgagg
     4021 cagagggcaa agccatcaaa ctggccaaag atgtggcttc ccttggatcc cagcttcagg
     4081 acacccaaga gctgctccaa gaagaaaccc ggcagaagct caatgtgtct accaagctgc
     4141 gtcagttgga agatgaaagg aacagcctgc aggaccagct ggatgaggag atggaggcta
     4201 agcaaaacct ggagcgccat gtctcaacac tgaacattca gctctcagac tctaagaaga
     4261 agctgcagga ctttgcaagt accatcgagg tcatggagga ggggaagaag aggttacaga
     4321 aagagatgga gggcctcagc cagcagtatg aggagaaggc ggctgcctat gacaaactgg
     4381 agaaaaccaa gaacaggctc cagcaggagc tggatgacct ggtcgtggac ttggacaacc
     4441 agcggcaact ggtatccaat ctggaaaaga agcagaagaa atttgaccag ttgttagctg
     4501 aggagaagaa catctcctcc aagtatgcgg atgagagaga ccgagctgaa gcagaggcca
     4561 gggaaaagga gacaaaggct ttgtctctag cccgggccct ggaggaagcc ctggaagcca
     4621 aagaagagct ggagaggacc aacaagatgc tcaaagctga gatggaagac ctggtcagct
     4681 ccaaggatga tgtaggcaag aacgtgcatg aactggagaa gtccaagcgt gccttggaga
     4741 cccagatgga agagatgaaa acccagctgg aggagttgga ggatgagctg caggccactg
     4801 aggatgccaa gctgcggcta gaggtcaaca tgcaggccct caagggccag tttgaacgcg
     4861 atctccaggc tcgggatgaa cagaatgagg agaagaggag gcagctacag cggcagctgc
     4921 acgagtatga gacagaactg gaagatgaac ggaagcagag agctctggcg gcggcagcta
     4981 agaagaagct ggaaggggac ctaaaagacc tagagctcca ggctgactca gccatcaaag
     5041 ggagggagga agccatcaag cagcttcgaa aactgcaggc tcagatgaag gacttccaaa
     5101 gagagctgga tgatgcccgt gcctccaggg atgagatctt tgccacctca aaagagaatg
     5161 agaagaaagc caagagtctg gaggcagacc tcatgcagct ccaagaggac ctggcagcag
     5221 ctgagagagc tcgcaagcaa gctgacctgg agaaggagga gctggccgag gagctggcta
     5281 gcagcttgtc aggaaggaat acactgcagg atgagaagcg ccgcctggag gcaaggatcg
     5341 cccaactaga ggaggagctg gaggaagagc agggcaacat ggaggccatg agtgatagag
     5401 tacgcaaggc cacactgcag gctgagcaac tgagcaatga gctggccaca gaacgcagca
     5461 cggctcagaa gaatgagagc gcacggcaac agctggagcg ccagaacaag gaactgcgaa
     5521 gcaagttgca ggaggtagaa ggtgctgtca aagccaagct caagtccact gttgcggcgc
     5581 tggaggccaa gattgcacag ctggaggagc aggttgaaca ggaggccaga gagaaacagg
     5641 cggccaccaa gtcgctgaag caaaaggaca agaagctaaa ggaggtcctg ctgcaggtgg
     5701 aggatgagcg caagatggca gagcagtaca aggagcaggc agagaaagga aacaccaagg
     5761 tcaagcagct gaagaggcag ctggaagagg cagaggagga gtcccagcgc atcaacgcca
     5821 accgcaggaa gctgcagcgg gagctagatg aggccacaga gagcaatgag gccatgggcc
     5881 gtgaggtgaa cgccctcaag agcaaactca ggagaggaaa cgaggcttca tttgttcctt
     5941 ccagaagggc tgggggccgt agagttattg aaaacacaga tggttctgaa gaagaaatgg
     6001 acgctcggga ctcagacttc aatggaacca aagccagtga ataaattcag gattggacac
     6061 catgtcaggg aaaacagaac actaaacgac agcagagccc agcagactgc ttagcacttg
     6121 tgtccattcg ttctcaagtc acagaaatca ctccacccct caccaggagt caaccacagc
     6181 cctgcacaaa gggtgtgaat tcaagttctt agatgggcta tcagagaaaa atccaaataa
     6241 gacgtacagg tcaggagcca cagtcaccag caactttgtt tacatgaaat gaggaagtta
     6301 catgaatggg tgccacagcc cccaacccac tcccaacctt tccctgacct gcctgacctt
     6361 ccagtttggg aggaaatccc gtttgaaaat tcccttccct ttcctgcctg ccacacctca
     6421 gacacacagt tcacttcgcc caagtgactt ttttagtcat ctgaattaaa aaaagaaaca
     6481 ctgctcccag agcgagcgga gcagagcaat cacacttatt tgcacccatg gtcactttca
     6541 ctaataaaag gttgtaagtc acga
//
