LOCUS       NM_008657               1254 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus myogenic factor 6 (Myf6), mRNA.
ACCESSION   NM_008657
VERSION     NM_008657.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1254)
  AUTHORS   Dias,A.P., Rehmani,T., Salih,M. and Tuana,B.
  TITLE     Tail-anchored membrane protein SLMAP3 is essential for targeting
            centrosomal proteins to the nuclear envelope in skeletal myogenesis
  JOURNAL   Open Biol 14 (10), 240094 (2024)
   PUBMED   39378988
REFERENCE   2  (bases 1 to 1254)
  AUTHORS   Tekko,T., Lozovska,A., Novoa,A. and Mallo,M.
  TITLE     Assessing Myf5 and Lbx1 contribution to carapace development by
            reproducing their turtle-specific signatures in mouse embryos
  JOURNAL   Dev Dyn 251 (10), 1698-1710 (2022)
   PUBMED   35618666
REFERENCE   3  (bases 1 to 1254)
  AUTHORS   Ghnaimawi,S., Zhang,S., Baum,J.I. and Huang,Y.
  TITLE     The Effects of Maternal Intake of EPA and DHA Enriched Diet During
            Pregnancy and Lactation on Offspring's Muscle Development and
            Energy Homeostasis
  JOURNAL   Front Physiol 13, 881624 (2022)
   PUBMED   35733999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1254)
  AUTHORS   Zhu,Q., Liang,F., Cai,S., Luo,X., Duo,T., Liang,Z., He,Z., Chen,Y.
            and Mo,D.
  TITLE     KDM4A regulates myogenesis by demethylating H3K9me3 of myogenic
            regulatory factors
  JOURNAL   Cell Death Dis 12 (6), 514 (2021)
   PUBMED   34011940
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1254)
  AUTHORS   Ojima,K., Muroya,S., Wada,H., Ogawa,K., Oe,M., Takimoto,K. and
            Nishimura,T.
  TITLE     Immature adipocyte-derived exosomes inhibit expression of muscle
            differentiation markers
  JOURNAL   FEBS Open Bio 11 (3), 768-781 (2021)
   PUBMED   33527775
REFERENCE   6  (bases 1 to 1254)
  AUTHORS   Braun,T., Rudnicki,M.A., Arnold,H.H. and Jaenisch,R.
  TITLE     Targeted inactivation of the muscle regulatory gene Myf-5 results
            in abnormal rib development and perinatal death
  JOURNAL   Cell 71 (3), 369-382 (1992)
   PUBMED   1423602
REFERENCE   7  (bases 1 to 1254)
  AUTHORS   Block,N.E. and Miller,J.B.
  TITLE     Expression of MRF4, a myogenic helix-loop-helix protein, produces
            multiple changes in the myogenic program of BC3H-1 cells
  JOURNAL   Mol Cell Biol 12 (6), 2484-2492 (1992)
   PUBMED   1588952
REFERENCE   8  (bases 1 to 1254)
  AUTHORS   Hannon,K., Smith,C.K. 2nd, Bales,K.R. and Santerre,R.F.
  TITLE     Temporal and quantitative analysis of myogenic regulatory and
            growth factor gene expression in the developing mouse embryo
  JOURNAL   Dev Biol 151 (1), 137-144 (1992)
   PUBMED   1374351
REFERENCE   9  (bases 1 to 1254)
  AUTHORS   Hinterberger,T.J., Sassoon,D.A., Rhodes,S.J. and Konieczny,S.F.
  TITLE     Expression of the muscle regulatory factor MRF4 during somite and
            skeletal myofiber development
  JOURNAL   Dev Biol 147 (1), 144-156 (1991)
   PUBMED   1715299
REFERENCE   10 (bases 1 to 1254)
  AUTHORS   Weintraub,H., Davis,R., Tapscott,S., Thayer,M., Krause,M.,
            Benezra,R., Blackwell,T.K., Turner,D., Rupp,R., Hollenberg,S. et
            al.
  TITLE     The myoD gene family: nodal point during specification of the
            muscle cell lineage
  JOURNAL   Science 251 (4995), 761-766 (1991)
   PUBMED   1846704
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155168.3.
            
            On Jun 23, 2018 this sequence version replaced NM_008657.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X59060.1, AK029370.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-538               AC155168.3         148782-149319       c
            539-629             AC155168.3         148407-148497       c
            630-1254            AC155168.3         147444-148068       c
FEATURES             Location/Qualifiers
     source          1..1254
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 55.96 cM"
     gene            1..1254
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /note="myogenic factor 6"
                     /db_xref="GeneID:17878"
                     /db_xref="MGI:MGI:97253"
     exon            1..538
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..748
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /note="muscle-specific regulatory factor 4"
                     /codon_start=1
                     /product="myogenic factor 6"
                     /protein_id="NP_032683.1"
                     /db_xref="CCDS:CCDS24162.1"
                     /db_xref="GeneID:17878"
                     /db_xref="MGI:MGI:97253"
                     /translation="MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPC
                     QDQMPQEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRE
                     RRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQEL
                     GVDPYSYKPKQEILEGADFLRTCSPQWPSVSDHSRGLVITAKEGGANVDASASSSLQR
                     LSSIVDSISSEERKLPSVEEVVEK"
     exon            539..629
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /inference="alignment:Splign:2.1.0"
     exon            630..1254
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1222..1227
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /note="hexamer: ATTAAA"
     polyA_site      1250
                     /gene="Myf6"
                     /gene_synonym="bHLHc4; herculin; MRF4"
                     /note="major polyA site"
ORIGIN      
        1 agaggccaag gaggagaaca tgatgatgga cctttttgaa actggctcct atttcttcta
       61 cttagatgga gaaaatgtga ctcttcagcc attagaagtg gcagagggct ctcctttgta
      121 tccagggagt gatggtaccc tatccccttg ccaggaccaa atgccccagg aagccgggag
      181 cgacagcagt ggagaggaac acgttctggc tcccccaggc ctgcagcctc cccactgccc
      241 tggccagtgt ctgatctggg cttgcaagac ttgcaagaga aaatctgccc ccacagatcg
      301 tcggaaagca gctaccctgc gcgaaaggag gagactaaag aaaatcaacg aagcctttga
      361 ggccctgaag cgtcggactg tggccaaccc caaccagaga ctgcccaagg tggagattct
      421 gcggagtgcc atcagctaca ttgagcgtct acaggacctg ctgcaccggc tggatcagca
      481 agagaagatg caggagctgg gcgtggaccc ctacagctac aaacccaagc aagaaattct
      541 tgagggtgcg gatttcctgc gcacctgcag cccccagtgg ccaagtgttt cggatcattc
      601 caggggcctc gtgataactg ctaaggaagg aggagcaaac gtggatgcct cagcctccag
      661 cagtcttcag cgcctttctt ccatcgtgga cagtatttct tcagaggaac gcaaactccc
      721 cagcgtggag gaggtggtgg agaagtaact cagccagcat ttggaacatt cttcacccag
      781 caggaagacc cccctttcca cctaatcatt tagattaggg ctcacagatg ccagctttta
      841 tgaaaggcga gagatttagt atttaaaaag aaacttctca ccacctcaag tgaaagtcct
      901 tcgccttggg gcttttatta tgatacttat tattatatcg gaacggctag tagcttagct
      961 ctagaaccct gattttgttt ttagtttggt tggttttaat aacatattaa cttttactat
     1021 gatcacgtga cccttttttg tcagttgcaa acgaagttca ttcctgtcta aatcaaagag
     1081 agaacgttta atcctaatag tatataatgt actttttgta aatagtctta gaactttcgt
     1141 ttctatgtaa acctaaagaa tatattttaa acgtggattt aacattgtat ataaaatgtg
     1201 tgaagatcct gatattgtaa tattaaaata ttaatacgtt tctacatgta caaa
//
