LOCUS       NM_001162417            7635 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus myelin basic protein expression factor 2, repressor
            (Myef2), transcript variant 1, mRNA.
ACCESSION   NM_001162417
VERSION     NM_001162417.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7635)
  AUTHORS   van Riel,B., Pakozdi,T., Brouwer,R., Monteiro,R., Tuladhar,K.,
            Franke,V., Bryne,J.C., Jorna,R., Rijkers,E.J., van Ijcken,W.,
            Andrieu-Soler,C., Demmers,J., Patient,R., Soler,E., Lenhard,B. and
            Grosveld,F.
  TITLE     A novel complex, RUNX1-MYEF2, represses hematopoietic genes in
            erythroid cells
  JOURNAL   Mol Cell Biol 32 (19), 3814-3822 (2012)
   PUBMED   22801375
  REMARK    GeneRIF: RUNX1 interacts with two novel protein partners, LSD1 and
            MYEF2, in erythroid cells.
REFERENCE   2  (bases 1 to 7635)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 7635)
  AUTHORS   Muralidharan,V., Tretiakova,A., Steplewski,A., Haas,S., Amini,S.,
            Johnson,E. and Khalili,K.
  TITLE     Evidence for inhibition of MyEF-2 binding to MBP promoter by
            MEF-1/Pur alpha
  JOURNAL   J Cell Biochem 66 (4), 524-531 (1997)
   PUBMED   9282330
REFERENCE   4  (bases 1 to 7635)
  AUTHORS   Haas,S., Steplewski,A., Siracusa,L.D., Amini,S. and Khalili,K.
  TITLE     Identification of a sequence-specific single-stranded DNA binding
            protein that suppresses transcription of the mouse myelin basic
            protein gene
  JOURNAL   J Biol Chem 270 (21), 12503-12510 (1995)
   PUBMED   7539003
REFERENCE   5  (bases 1 to 7635)
  AUTHORS   Steplewski,A., Haas,S., Amini,S. and Khalili,K.
  TITLE     Regulation of mouse myelin basic protein gene transcription by a
            sequence-specific single-stranded DNA-binding protein in vitro
  JOURNAL   Gene 154 (2), 215-218 (1995)
   PUBMED   7534248
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929451.8 and AL928902.16.
            
            On Feb 28, 2022 this sequence version replaced NM_001162417.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK048404.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               AL929451.8         30029-30240         c
            213-421             AL929451.8         23309-23517         c
            422-474             AL929451.8         22082-22134         c
            475-482             AL929451.8         20687-20694         c
            483-576             AL929451.8         20493-20586         c
            577-768             AL929451.8         17124-17315         c
            769-922             AL929451.8         16314-16467         c
            923-972             AL929451.8         15798-15847         c
            973-1036            AL929451.8         15600-15663         c
            1037-1138           AL929451.8         6963-7064           c
            1139-1189           AL929451.8         5441-5491           c
            1190-1258           AL929451.8         5094-5162           c
            1259-1357           AL929451.8         4621-4719           c
            1358-1429           AL929451.8         4207-4278           c
            1430-1638           AL929451.8         2556-2764           c
            1639-1690           AL929451.8         2352-2403           c
            1691-1865           AL928902.16        161080-161254       c
            1866-1892           AL928902.16        159894-159920       c
            1893-7635           AL928902.16        153191-158933       c
FEATURES             Location/Qualifiers
     source          1..7635
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 61.16 cM"
     gene            1..7635
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="myelin basic protein expression factor 2,
                     repressor"
                     /db_xref="GeneID:17876"
                     /db_xref="MGI:MGI:104592"
     exon            1..212
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            213..421
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            422..474
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            475..482
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            483..576
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            577..768
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            769..922
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            923..972
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1036
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1138
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1189
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1258
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1357
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1429
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1638
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1690
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1865
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1892
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..7635
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1982..1987
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="hexamer: AATAAA"
     polyA_site      2006
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="major polyA site"
     regulatory      2654..2659
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="hexamer: AATATA"
     polyA_site      2680
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
     regulatory      3987..3992
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="hexamer: AATAAA"
     polyA_site      4016
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
     regulatory      6217..6222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="hexamer: AATAAA"
     polyA_site      6242
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
     regulatory      7614..7619
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
                     /note="hexamer: ATTAAA"
     polyA_site      7635
                     /gene="Myef2"
                     /gene_synonym="9430071B01; mKIAA1341"
ORIGIN      
        1 atccgttacc gcttctccgg ccgccgccat tgtagcgctc ggagccctca tcgcggccga
       61 ggcggagccc gcggcgggat ggccgatgcc gacaagtccg aggcggccgc gggtgacgac
      121 ggctcgcagc agcaaccggc tgagccgcgg cgagacacgc accccggcga gcccgagaaa
      181 ccgccgcgca gcagcgccaa cggcgttaaa atggagaatg atgagtcagt gaaggaagaa
      241 aaatctgatt taaaagaaaa gtctacagga aataagaagg ccaatcggtt ccatccttat
      301 tcaaaagata agaattcggg cactggagaa aagaaaggtc caaatcggaa cagagtgttc
      361 attagcaaca taccctatga catgaagtgg caggctatta aagatttgat gagagaaaaa
      421 gttggtgagg ttacatacgt ggagctcttt aaggatgcgg aaggaaaatc aaggggttgt
      481 ggcgtggttg aattcaaaga tgaagaattt gtaaagaaag cattagaaac tatgaacaaa
      541 tatgacctta gtggaaggcc tttgaatatt aaagaggatc cggatggaga aaatgctcgc
      601 cgggcactgc agcgaacagg aacatcattt caaggatcac atgcctccga tgtgggatct
      661 gggttggtga atttaccacc ttccattctc aataatccaa acattcctcc tgaggttatc
      721 agcaatttgc aggctggtag acttggttcc acaatttttg ttgctaatct tgacttcaaa
      781 gttggttgga agaaattaaa ggaagtgttc agcatagctg gaactgtgaa gcgagctgat
      841 attaaagaag acaaggatgg caagagcaga ggcatgggca ctgtcacttt tgagcaggca
      901 attgaagcag tccaagcaat ttccatgttc aatgggcagt ttttatttga tagacctatg
      961 catgtgaaaa tggatgacaa atctgtccct catgaagact accgttcaca tgatagtaag
     1021 acatcacagt taccacgtgg tcttggaggc attggaatgg gacttggtcc aggtggacag
     1081 cctattagtg ccagccagct gaacataact ggtgtaatgg gaaatttggg tccaagtggt
     1141 atgggaatgg atggtccggg ttttggagga gtgaatagaa ttggaggagg agttgggttt
     1201 ggtggtctgg aagcaatgaa tagcatggca ggctttggtg gagttggccg aatgggagag
     1261 ctataccgtg gtgcaatgac tagtagcatg gagcgagatt tcggacgtgg tgatattgga
     1321 ttaagtcgag gctttggcga ttcctttggt agacttggca gtgcaatgat tggagggttt
     1381 gcaggaagaa taggagcttc taacatgggt ccagtaggaa ctggaataag cggcagcatg
     1441 agcggcatga gcactgtgac tggaggcatg ggcatgggac tggaccgcat gagctccagc
     1501 ttcgacagga tggggccagg cattggagcc atactggaaa ggagcatcga tgtagaccga
     1561 gggtttttat caggtcccat gggaagcgga atgagagaca gattaggctc caaaggcaac
     1621 cagatatttg ttagaaatct tccttttgac ttgacttggc agaaattaaa agagaaattc
     1681 agccaatgtg gtcatgtaat gtttgcagag ataaagatgg agaatggcaa gtcaaaaggc
     1741 tgtgggacag tcaggtttga atctgcagag tcagcggaaa aggcctgcag gatcatgaat
     1801 ggcatcaaga tcagcggcag ggaaatcgat gtgcgcttgg accgcaatgc gtaatttcaa
     1861 gcatgtgaat taccatctaa ttcacatttc agtttgcctg atgtcaaata tgttcttatt
     1921 gggaaaaatt ggatacggca aatatgcaag ctacctggac attcttatct tcttcatgaa
     1981 aaataaaact attttgtttt tgtttatttg ttagcataca gttacaataa agttagttat
     2041 ctgggagaag tcagaccagc cagtttggag agggttccag gtagtagtta ttccaactct
     2101 acagtgtttg aatttgtgtt gtaattcttt agccccagca gtgtgaggac agcagtgtgt
     2161 acatgttagt aggtgtctgg gcccagctgt ggtcagtgaa gcttcactgg tacaatctgg
     2221 ttgcatgatt taggcatgga ggaaagagta ttcacttcta atgggtatat tacaactaag
     2281 tgataaaatg tactctggaa gatgctagaa acctaaaaac aaaactttga ttctcattat
     2341 tcatttgcat tgtatttgtg atacatattt aaagcaaaag aaaataccat ctactcaaac
     2401 agagagcacc tactgctttc tgttgacccc agtcatctct actttctact atggattaga
     2461 attcactttt atgaagaatt ctcatgaaac ctgtgtaatt ataaacatat ccaatgaatt
     2521 atacccctga ctgtgtcata gcatacatag gaaatgcttt tgatatgtaa ctcacaaaaa
     2581 catgaatgag cttgctggtt ttgctgttaa agctttcata ttttgtaaat agtttttagt
     2641 cttgctgaaa aaaaatatat gctcccaaga ttactttaaa tgaatacttc caatttgttt
     2701 ttacatggaa taattttctt gtgctattat acttaaattc catacctgtt actgtgacca
     2761 tccaaactag gatgtatgtg aatgcagata tccatagtgc agacatgaaa aaggttatca
     2821 caaagtaatt tttccaaaac tttctcctgc agtctggtgt tgtcagagca agtaatgtaa
     2881 taataggaag agagagaacc caaaaaattc ttcttaagtc tgcttctggc atgctgaaaa
     2941 cacttggtgg atctgtggtg ggaaagttca acattttgag ttttctcaaa tgtgcaatta
     3001 tgttagaaag gcccatttag aaggctgttt tgaagtaagt tactgtatgc atcttttaaa
     3061 gaccgtctag aacagtagtc tcaacctgtg ggacttgacc cctttggtgt tgaacaacca
     3121 ttttacaagg gccacctaag accctgagaa gtctcagata cttacattac aatttataac
     3181 agcaaaatta cagttctatg tagtgtcaat gaaaataatt ttatgggtga aagttaccac
     3241 aataagaggg actgtgtcaa acggtctcag cattaggaaa attgagaagc actggtctag
     3301 aacattggaa tactcattac tattactgct ggtcagaaga aatgtaacta aaactaggca
     3361 gacagtataa gctgtgctct acatccctta accgactgct cgaatcaaat atcttgaact
     3421 gtttgctgaa tgtgctggtg acagtgttca cggagttgaa agtaggattt gcttgcttta
     3481 ctgtagtatg ggttcattag agacgtgatg ctttctctcc cagctctttc actcctcatc
     3541 tcttttccaa aacggacgct gcttatgctt tgttgcacac tgatgcacgc ttagggagtg
     3601 ttccctctaa ctctcactgt gccgcatcgt ttactgaacg caggcttccc gggtgctaga
     3661 aggaatctag agaaggttgg gcctagcatc cttggtatag ttccggggtg tgctctagaa
     3721 tggtgaggag attggataaa agtgggacga ggctgtacac taatgaatat gttaagtatg
     3781 tgaaggttgg atcaaatcac aaatattatt ataactcata aaagctcacc aagactcaga
     3841 cagtgcacca ttaatttaga cacagattct agcatgaaca tttttgacta gttctttgga
     3901 gtctttgttg ttttaaatct cctcagtctt aaagactaca aagtatggtt tgtaaaaata
     3961 aatgtctcgt gtcaaaattt taaagtaata aattagaagc ttgcttctca attacctaac
     4021 tgaagttgga accactttta taaaagcttt tctagtctgg aatgctattg ctatatcgag
     4081 cataccaagc tcatgtgctg cttcacacgg catgtttaag ttacacctgc gttcttttcc
     4141 ccattctgtt cccctgaatc atcccctttc cttttattga cagttgttac aaagatgttc
     4201 tttctttctt agtgaaaatc caagctccag cgttgtctct gctccctctc tggctcggca
     4261 ttgctgccat agtttggtgc tgctgcttct actgtgtctc ataattcatc cccctgcctt
     4321 ttctgttttg ttcctgtcct ttcatcttag ctcagtcttc tgtgaacatt gggtgagaga
     4381 aaagagccta acatgcatct ctgactctgt cttaggaatg ctgcctgctc agtggggtat
     4441 cttgcacgac ctcctgcact tccttcctgt cagcctgctc ctctgctgct tgctgcactt
     4501 gcatgtgttg gctctgtgtg caagcatgtg agcaggcctt tgctagtgtt cccaggcctc
     4561 agtccagagc atacttatac ccctgaatca tgtatgcaat aaaagtgtca gctgttgctt
     4621 cctgactaca catactatta gattattgag ttaaagcctc tcttatccca tggggcccaa
     4681 accaattcaa atgctccttt ctccatgtgc atctcccatc tgagtgtcat caaagtttat
     4741 tcagtctgcc tgtatgaacc atggtattag cagtttatgt ttgcttatgg tgttcacact
     4801 ttgaaattct agctgatttc attctgtgtc tgggaaatgg ctcagtgggt aaagcgcttg
     4861 gtgcacgggc atgagagtct gagatcagat tctcaacacc acataaaaaa gcatggcagc
     4921 ccacatgtat actctcagtg ctatggaagt cagagacaga cagatcccta aagttcactg
     4981 gccagctagt ctagcctaat cagtgagcta caggttcatt gaatgactgt ggtctcaaaa
     5041 aatgatgtga agtctcaaag aattgagggc tagcatccat gactgactct ggcctccatg
     5101 tctgtgtgtt ctcccttccc ccacactttt agctgattaa aaaaaaaatt attgtgagtt
     5161 ccttaaaggc caggacttac ttgcagttca tcatctctgg ctccatagtg tgttgtgtaa
     5221 ccatgtacta attactaact ctcaatgaga actcaggtct tttagagtgt tagatggcag
     5281 ggtgtagttg ttaccttcag aaacctgact aagaccatgc aagcttagag aaagttggga
     5341 gtaaccggaa tcttcctgaa atattccact gtctgtcctt gactggcgac gaatgaagag
     5401 ctggctctca tcctcccatc ccaacagtgt ctgctgttca attctctcct ccatagctct
     5461 ggcaaggcag ggacaacagg gactgcatgt tttcatgaca tgccggctga tcgtggtgtc
     5521 aaaacacagc agcagaacat agagcccata tatcagtagc agccctgctc cttcgtacct
     5581 agacgtggag gaaagggctg tgcagttatc cagtcatttt aaacaatatt ctctaacaaa
     5641 agcaacagtg gaaaattcaa ggaaccactc ctaaatgctt ttatttaccc agttttggtt
     5701 atagtatggt tacaaattca ttgattaaaa aatctgcctc tttaaaaagt aatataaaat
     5761 ccattgtctg actttataga ttcctttcaa gtaataggca caaaatagtc ggagagttaa
     5821 aactaattaa tagatatttt ttcagttcat ttatttagca tactacattt ctcaaatatt
     5881 taataattag aaaataaaat actatctctt agattttctg atacagaaac atggtgtaga
     5941 atacttagac tgtgctaggt ttttgctgga gctttgcagt ttgttttaca gagattcaga
     6001 ggaaagccgg aggtggtggg gtgttgttgg ctttgaggtc tcattgtaaa agcccagact
     6061 ggccttgaac actgcaccct agattggcct cagacactca gattattatc ctcctacctc
     6121 ttccacttga gttttggggg ttttatatct gtactactat gcttggtccc tttttgatga
     6181 attgattgta gcttaattgg gtttatattc ataagaaata aagaatattc tcaaaaatga
     6241 aattctggca tacagcacca agaattgtct atgctttggt ttcccatttt actgtgtatt
     6301 aggctaattt ttatcacatt aatattgtta ttttatttca tagcagagaa tcacttctct
     6361 gcttcaacta aaaaaaaaaa agaaagaaag agaaaaaaaa gagttcctga tttccttggt
     6421 tcctgtcatt tacaagtgac agctgaattc cagtgttttt gctatactag caacctgact
     6481 tttatcttgc tttctccctg tttggattct gtggacacac acacatgtgg tggccatatg
     6541 ttttatatca cttttttatg gtatccagca tagaacacct aggacaattg ttctcacagc
     6601 cctttggggc ttgaatggcc ctatgacagg ggtcacttaa gaccatctgc atgtcagata
     6661 acttacacaa tgatcataac agcagcaaca ttacagttat gaaatagcaa caaaaataat
     6721 ggttgtgggt ccaccatgag gaactgttag gggctcagag cagcaggatg cctgggaaca
     6781 ctggcagaac cgctgtgtgt gcctgtttgg caagttcacg tctttccacc aaattagctg
     6841 ccttttccag ttttcttgga cctgttaggt acagagatta tggaaaagca gcaagccttt
     6901 ttgatggtga cacataattc tgggttgtta aagaaggcag cagttcttcc catccttctc
     6961 ttctgggagg atgggaggag tgcaagggct tctgctggcc tccaggcttt tattactatg
     7021 accctttctt tttaaccaag gccaggtaag caacagcagc cggggaaggt gtgaacatgg
     7081 agaccaagga aaaggaagaa tggctgtctt cagtgactag gacaggagag aaaagcagcc
     7141 accagcagtt ttgaaggagt cagctgagac tgcaatagct gttgaagtga aggttttgag
     7201 aaactatact actaagccat cagacttcaa aaattctgta attatgtttt atgttaagag
     7261 tgacacttat ttaaagctta ccagtaaatt cggttgtcaa atattatgcc aaaaactgct
     7321 cctacactaa ctgcatacac tgcacagtct cggaagaggg gccagcagga gagtgttgaa
     7381 acctggaaaa tgatggtttg atttactgtg tgcattacag tgtaaggcat tcaagaacag
     7441 tgtataatac tgaaatcacg tatatttgtg gtaaactatt gttaagtttg catattacgt
     7501 agagaaaaac aattttaaag taaaattgta tataaacctg tactgacttt tataaatttc
     7561 attaagagat gcttatggat tatgtcaatt gagtaaatgt ttttctagtg gttattaaat
     7621 ttgactgaat gcaat
//
