LOCUS       NM_001303121            3323 bp    mRNA    linear   ROD 18-DEC-2022
DEFINITION  Mus musculus v-myc avian myelocytomatosis viral oncogene lung
            carcinoma derived (Mycl), transcript variant 2, mRNA.
ACCESSION   NM_001303121 XM_006502820
VERSION     NM_001303121.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3323)
  AUTHORS   Anderson DA, Ou F, Kim S, Murphy TL and Murphy KM.
  TITLE     Transition from cMyc to L-Myc during dendritic cell development
            coordinated by rising levels of IRF8
  JOURNAL   J Exp Med 219 (2) (2022)
   PUBMED   34958351
REFERENCE   2  (bases 1 to 3323)
  AUTHORS   Hirano M, So Y, Tsunekawa S, Kabata M, Ohta S, Sagara H, Sankoda N,
            Taguchi J, Yamada Y, Ukai T, Kato M, Nakamura J, Ozawa M, Yamamoto
            T and Yamada Y.
  TITLE     MYCL-mediated reprogramming expands pancreatic insulin-producing
            cells
  JOURNAL   Nat Metab 4 (2), 254-268 (2022)
   PUBMED   35145326
REFERENCE   3  (bases 1 to 3323)
  AUTHORS   Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner
            S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE,
            Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I,
            Nord AS and Rubenstein JL.
  TITLE     Transcriptional network orchestrating regional patterning of
            cortical progenitors
  JOURNAL   Proc Natl Acad Sci U S A 118 (51) (2021)
   PUBMED   34921112
REFERENCE   4  (bases 1 to 3323)
  AUTHORS   Lowenstein ED, Rusanova A, Stelzer J, Hernaiz-Llorens M, Schroer
            AE, Epifanova E, Bladt F, Isik EG, Buchert S, Jia S, Tarabykin V
            and Hernandez-Miranda LR.
  TITLE     Olig3 regulates early cerebellar development
  JOURNAL   Elife 10, e64684 (2021)
   PUBMED   33591268
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3323)
  AUTHORS   Williams JW, Zaitsev K, Kim KW, Ivanov S, Saunders BT, Schrank PR,
            Kim K, Elvington A, Kim SH, Tucker CG, Wohltmann M, Fife BT,
            Epelman S, Artyomov MN, Lavine KJ, Zinselmeyer BH, Choi JH and
            Randolph GJ.
  TITLE     Limited proliferation capacity of aortic intima resident
            macrophages requires monocyte recruitment for atherosclerotic
            plaque progression
  JOURNAL   Nat Immunol 21 (10), 1194-1204 (2020)
   PUBMED   32895539
REFERENCE   6  (bases 1 to 3323)
  AUTHORS   Haefliger JA, Bruzzone R, Jenkins NA, Gilbert DJ, Copeland NG and
            Paul DL.
  TITLE     Four novel members of the connexin family of gap junction proteins.
            Molecular cloning, expression, and chromosome mapping
  JOURNAL   J Biol Chem 267 (3), 2057-2064 (1992)
   PUBMED   1370487
REFERENCE   7  (bases 1 to 3323)
  AUTHORS   Christy BA, Sanders LK, Lau LF, Copeland NG, Jenkins NA and Nathans
            D.
  TITLE     An Id-related helix-loop-helix protein encoded by a growth
            factor-inducible gene
  JOURNAL   Proc Natl Acad Sci U S A 88 (5), 1815-1819 (1991)
   PUBMED   2000388
REFERENCE   8  (bases 1 to 3323)
  AUTHORS   Semsei I, Ma SY and Cutler RG.
  TITLE     Tissue and age specific expression of the myc proto-oncogene family
            throughout the life span of the C57BL/6J mouse strain
  JOURNAL   Oncogene 4 (4), 465-471 (1989)
   PUBMED   2470008
REFERENCE   9  (bases 1 to 3323)
  AUTHORS   Ingvarsson S, Sundaresan S, Jin P, Francke U, Asker C, Sumegi J,
            Klein G and Sejersen T.
  TITLE     Chromosome localization and expression pattern of Lmyc and Bmyc in
            murine embryonal carcinoma cells
  JOURNAL   Oncogene 3 (6), 679-685 (1988)
   PUBMED   2577870
REFERENCE   10 (bases 1 to 3323)
  AUTHORS   Zimmerman,K.A., Yancopoulos,G.D., Collum,R.G., Smith,R.K.,
            Kohl,N.E., Denis,K.A., Nau,M.M., Witte,O.N., Toran-Allerand,D.,
            Gee,C.E. et al.
  TITLE     Differential expression of myc family genes during murine
            development
  JOURNAL   Nature 319 (6056), 780-783 (1986)
   PUBMED   2419762
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CJ164908.1, AL606906.18 and
            BC053059.1.
            
            [WARNING] On May 11, 2023 this sequence was replaced by
            NM_001303121.2.
            
            On Dec 19, 2014 this sequence version replaced XM_006502820.1.
            
            Summary: This gene encodes a basic helix-loop-helix leucine zipper
            (bHLHZip) protein that heterodimerizes with another bHLHZip protein
            to drive transcription of targets important for proliferation,
            apoptosis and differentiation. Mice lacking this gene product show
            marked decrease in T-cell priming during bacterial and viral
            infections. In humans, this gene was found to be amplified in
            small-cell lung cancers. Alternate splicing of this gene results in
            multiple variants. [provided by RefSeq, Dec 2014].
            
            Transcript Variant: This variant (2) uses an alternate splice site
            in the 5' region and initiates translation at an alternate start
            codon, compared to variant 1. The encoded isoform (2) has a
            distinct N-terminus and is longer than isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089346.1, AK146959.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               CJ164908.1         1-145
            146-220             AL606906.18        137758-137832
            221-725             AL606906.18        138196-138700
            726-3299            AL606906.18        141587-144160
            3300-3323           BC053059.1         3495-3518
FEATURES             Location/Qualifiers
     source          1..3323
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 57.36 cM"
     gene            1..3323
                     /gene="Mycl"
                     /gene_synonym="bHLHe38; L-myc; Lmyc-1; Lmyc1; Mycl1"
                     /note="v-myc avian myelocytomatosis viral oncogene lung
                     carcinoma derived"
                     /db_xref="GeneID:16918"
                     /db_xref="MGI:MGI:96799"
     exon            1..220
                     /gene="Mycl"
                     /gene_synonym="bHLHe38; L-myc; Lmyc-1; Lmyc1; Mycl1"
                     /inference="alignment:Splign:2.1.0"
     exon            221..725
                     /gene="Mycl"
                     /gene_synonym="bHLHe38; L-myc; Lmyc-1; Lmyc1; Mycl1"
                     /inference="alignment:Splign:2.1.0"
     exon            726..3306
                     /gene="Mycl"
                     /gene_synonym="bHLHe38; L-myc; Lmyc-1; Lmyc1; Mycl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcgggaaa caatgcgcct gcagatcgcg ctcccgcgtc gatcccggga gcgtcctggc
       61 tgccgtgtgc gagcgaggcg gggggcgcgc gcacgggggg cgcgctcgtg agtgcggggc
      121 cgcgcgctcg gtggcgcgca tgtgtgtgtg tgcgggctgc cgggcttccc cgagccggcg
      181 gggagccgct ccgctccagg tggcgggcgg cgggagcgag ggagcggaca tggacttcga
      241 ctcgtatcag cactatttct acgactatga ctgcggagag gatttctacc gctccacggc
      301 gcccagcgag gacatctgga agaaattcga gctggtgccg tcgcccccca cgtcgccgcc
      361 ctggggctcc ggtcccggcg ccgtggaccc agcctctggg attaatcccg gggagccgtg
      421 gcctggaggg ggtgccgggg acgaggcgga atctcggggc cattcgaaag cctggggcag
      481 gaattatgct tccatcattc gccgtgactg catgtggagc ggcttctccg cccgagaacg
      541 gctggagaga gtggtgagcg acaggctggc cccaggcgcg ccccggggga acccgcccaa
      601 agcgcccgct accccggacg gcactcctag tctggaagcc agtaacccgg cgcccgccac
      661 ccaatgtcag ctgggcgagc ccaagactca ggcctgctcc gggtccgaga gccccagcga
      721 ttctgaaggt gaagagattg acgtggtgac cgtggagaag aggcgatctc tggacatccg
      781 aaagccagtc accatcacgg tgcgagcaga ccccctggac ccctgcatga agcacttcca
      841 tatctctatc caccaacagc agcataacta tgctgcccgt tttcctccag aaagttgctc
      901 tcaagagggg gatcctgagc caggtcccca ggaagaggct ccggagatag aagctcccaa
      961 ggagaaagag gaggaggaag aggaagagga ggaagaagag attgtgagcc ccccacctgt
     1021 cggaagtgag gctccccagt cctgccaccc caaacctgtc agttctgaca ctgaggacgt
     1081 gaccaagagg aagaaccata acttcttgga acgaaaaagg aggaatgacc tccgctcccg
     1141 gttcctagcc ctgcgggacc aggttcccac cctggccagc tgctctaagg cccccaaagt
     1201 cgtgatcctc agcaaggcgt tagaatactt gcaggctttg gtgggggctg aaaagaaaat
     1261 ggctacagag aaaaggcagc tccggtgtcg gcaacagcaa ctgcaaaaga gaatcgcgta
     1321 cctcagtggc tactaaccga ccagaacgcc tgacttcttg gtctcacaga cacaagctta
     1381 ttgtttaacc tctctctccc ttttagtaat ttgcacattt tggttacagc ggggggggca
     1441 gtctggacag tagatcccag aatgcattgc agccggtgtg cgcacacaat aagggcttgc
     1501 attcttggta acctcgaaac ccaattctcc ctcttccccg accgactcat gggaatgctg
     1561 tccttctctg gcgcctttgg cttctcagca ggcagctact gaggagattt ggggtctgct
     1621 tagctcacta gctcctgacg aaaggctgac agatgctatg caacaggtgg tggacgttgt
     1681 tggggctgca gcctacgtga aatctcacac tgtgctgggg cttcaggcta ggaaaggatg
     1741 ctgctctcac tgctgtctct ggggatgatc tgaggacagc tgggcctgga tactgtcccc
     1801 caggctccgt tttccaggag gcaagcgagc tgtcccgggc gaagacaagc tcgcagactt
     1861 gatcagcatg gagcattacc tcaccgtcag acactttaca gtagctgtgg agtggaaacc
     1921 tttaagatag atttggatgg taggccacac ccttccctgc acgctcaatg ctatgacttt
     1981 gagaaagggc ttggcctcta tgtagagtct ttgtctcaga gttctctggg ccttctcaga
     2041 gagggacctt tctatcctca caagggacct ttttgtttct tcctgccttt gttatgcaat
     2101 ggccaccaca gcaccctttc acaccgacca gaaatatttc cccaggacat agggaaatgg
     2161 gtcacagccc aggacctggg gaagccttgg catccccact catgaccaac ggtccttgcc
     2221 caggttttct gcagggctat ttgaggccca gcttggaacc ttttctcgag gcagatagtt
     2281 acaaggtgcc tctgaaggac aagccctatc gcttcctctt tcccacctgc ctctctgtca
     2341 gatcttgact ctgtctacaa tctgctggaa cagtgcaaac ctgtccttct cgagcaactt
     2401 tgctggctct gcagccacca tcctgattct ctgccggcct gagtcacatc ctttcccctg
     2461 gaatctgggc cttacagaga gattcagagg ggcaccgctt gcattcacct gatgccccca
     2521 gaaggtaaac ttacttcctg gtgggttgtc agtgtacctc taggaacgct actcagccaa
     2581 caaggagagt ttgctccagc tgtgttctgc aactccctgt ggaatcaaag tacagccctc
     2641 tatcctggga aagtcaccaa gctagcagcc gtcacgtgag catctttcag gagatcctaa
     2701 gctttgcctg aaagaagagc cagcctttcc agaactctac ccaggaaagc agatctgttc
     2761 ctgctggccc tgggcttgga agtaggggta cagtgtgggg gacagacagt aagtaacaac
     2821 atgtggctct caaaaaccag ctaccacttc caaattggct cccaactgtg atggcctcca
     2881 attacttcct ggcctcaagt cctagaggaa gcttcggaag ttgctgttgt acctgttggg
     2941 gcaggacttc taggcaccaa gggactcctg gaactatctt gggaggacaa gtggtgaaca
     3001 ggctaaagtc tcatctgaat ggcttgtgtt ttataagctg ctgcggggtt gtatgctgtg
     3061 ggcgtctttt gtttttgttt ttgctttttt ttttaatact gtatttttgt atgctttttt
     3121 gcaaagtggt gttaactgtt tttgtataag aaaaacaaaa aacaaaaacc ctcctgttgc
     3181 aagggtctgg tttattttga aaggtgcatt tacctgaaat tttgtattta gttgtaatca
     3241 ttaattgctt gattttaaac tgttgccttc tgggacatct tctaataaaa agatttctca
     3301 aaaaaaaaaa aaaaaaaaaa aaa
//
